JP2019537108A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2019537108A5 JP2019537108A5 JP2019518269A JP2019518269A JP2019537108A5 JP 2019537108 A5 JP2019537108 A5 JP 2019537108A5 JP 2019518269 A JP2019518269 A JP 2019518269A JP 2019518269 A JP2019518269 A JP 2019518269A JP 2019537108 A5 JP2019537108 A5 JP 2019537108A5
- Authority
- JP
- Japan
- Prior art keywords
- genes
- expression
- patient
- status
- listed
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 108090000623 proteins and genes Proteins 0.000 claims description 149
- 230000014509 gene expression Effects 0.000 claims description 139
- 238000000034 method Methods 0.000 claims description 114
- 206010028980 Neoplasm Diseases 0.000 claims description 90
- 201000011510 cancer Diseases 0.000 claims description 78
- 239000000523 sample Substances 0.000 claims description 43
- 239000000090 biomarker Substances 0.000 claims description 24
- 238000004458 analytical method Methods 0.000 claims description 20
- 206010060862 Prostate cancer Diseases 0.000 claims description 17
- 208000000236 Prostatic Neoplasms Diseases 0.000 claims description 13
- 238000007619 statistical method Methods 0.000 claims description 13
- 238000004422 calculation algorithm Methods 0.000 claims description 8
- 238000010801 machine learning Methods 0.000 claims description 8
- 239000013610 patient sample Substances 0.000 claims description 7
- 238000002493 microarray Methods 0.000 claims description 6
- 210000002307 prostate Anatomy 0.000 claims description 6
- 108700039887 Essential Genes Proteins 0.000 claims description 4
- 238000001574 biopsy Methods 0.000 claims description 4
- 238000007637 random forest analysis Methods 0.000 claims description 4
- 239000008280 blood Substances 0.000 claims description 2
- 210000004369 blood Anatomy 0.000 claims description 2
- 210000000416 exudates and transudate Anatomy 0.000 claims description 2
- 238000011471 prostatectomy Methods 0.000 claims description 2
- 210000003296 saliva Anatomy 0.000 claims description 2
- 210000000582 semen Anatomy 0.000 claims description 2
- 238000012360 testing method Methods 0.000 claims description 2
- 210000002700 urine Anatomy 0.000 claims description 2
- 238000010837 poor prognosis Methods 0.000 claims 10
- 241000269627 Amphiuma means Species 0.000 claims 1
- 238000000354 decomposition reaction Methods 0.000 claims 1
- 238000001727 in vivo Methods 0.000 claims 1
- 229920000642 polymer Polymers 0.000 claims 1
- 239000003814 drug Substances 0.000 description 2
- 229940124597 therapeutic agent Drugs 0.000 description 2
- 208000014061 Extranodal Extension Diseases 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 238000007477 logistic regression Methods 0.000 description 1
- 229920002521 macromolecule Polymers 0.000 description 1
- 238000004393 prognosis Methods 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022147254A JP7539443B2 (ja) | 2016-10-05 | 2022-09-15 | 癌の分類および予後 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1616912.0 | 2016-10-05 | ||
| GBGB1616912.0A GB201616912D0 (en) | 2016-10-05 | 2016-10-05 | Classification of cancer |
| PCT/EP2017/075368 WO2018065525A1 (en) | 2016-10-05 | 2017-10-05 | Classification and prognosis of cancer |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022147254A Division JP7539443B2 (ja) | 2016-10-05 | 2022-09-15 | 癌の分類および予後 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019537108A JP2019537108A (ja) | 2019-12-19 |
| JP2019537108A5 true JP2019537108A5 (enExample) | 2020-11-19 |
| JP7365899B2 JP7365899B2 (ja) | 2023-10-20 |
Family
ID=57571107
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019518269A Active JP7365899B2 (ja) | 2016-10-05 | 2017-10-05 | 癌の分類および予後 |
| JP2022147254A Active JP7539443B2 (ja) | 2016-10-05 | 2022-09-15 | 癌の分類および予後 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022147254A Active JP7539443B2 (ja) | 2016-10-05 | 2022-09-15 | 癌の分類および予後 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US11746380B2 (enExample) |
| EP (1) | EP3523443B1 (enExample) |
| JP (2) | JP7365899B2 (enExample) |
| AU (2) | AU2017341084B2 (enExample) |
| CA (1) | CA3038743A1 (enExample) |
| GB (1) | GB201616912D0 (enExample) |
| WO (1) | WO2018065525A1 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2018266632B2 (en) * | 2017-05-12 | 2024-07-25 | The Henry M. Jackson Foundation For The Advancement Of Military Medicine. Inc. | Prostate cancer gene profiles and methods of using the same |
| US11894139B1 (en) * | 2018-12-03 | 2024-02-06 | Patientslikeme Llc | Disease spectrum classification |
| CN109637589B (zh) * | 2018-12-13 | 2022-07-26 | 上海交通大学 | 基于频繁模式和机器学习双推荐制的核定位信号预测方法 |
| GB2612911B (en) * | 2019-02-14 | 2023-11-22 | Mirvie Inc | Methods and systems for determining a pregnancy-related state of a subject |
| CN111796095A (zh) * | 2019-04-09 | 2020-10-20 | 苏州扇贝生物科技有限公司 | 一种蛋白质组质谱数据处理方法及装置 |
| GB201915464D0 (en) * | 2019-10-24 | 2019-12-11 | Uea Enterprises Ltd | Novel biomarkers and diagnostic profiles for prostate cancer |
| EP4204813A4 (en) * | 2020-08-28 | 2024-11-27 | The Johns Hopkins University | Urinary glycoproteins for the early detection and treatment of aggressive prostate cancer |
| JP7774310B2 (ja) * | 2020-09-30 | 2025-11-21 | 国立大学法人 長崎大学 | 腎がん患者の抗がん剤抵抗性および予後予測方法、抗腎がん物質のスクリーニング方法、ならびに、腎がん治療用医薬組成物 |
| CN112365948B (zh) * | 2020-10-27 | 2023-07-18 | 沈阳东软智能医疗科技研究院有限公司 | 癌症分期预测系统 |
| CN116324874A (zh) * | 2020-11-06 | 2023-06-23 | 威里利生命科学有限责任公司 | 对前列腺癌预后的人工智能预测 |
| CN114540492A (zh) * | 2022-01-10 | 2022-05-27 | 中山大学肿瘤防治中心（中山大学附属肿瘤医院、中山大学肿瘤研究所） | 检测SCN4A和SCN7A mRNA表达量的产品在制备肝癌预后预测产品中的应用 |
| US20250290150A1 (en) * | 2022-05-04 | 2025-09-18 | The Regents Of The University Of California | Methods and systems for characterization, diagnosis, and treatment of cancer |
| KR102870357B1 (ko) * | 2022-07-21 | 2025-10-13 | 인제대학교 산학협력단 | 인공지능 기술에 기반한 전립선암 조직의 세포 핵의 클러스터 분석 시스템 및 방법 |
| CN117385041A (zh) * | 2022-09-03 | 2024-01-12 | 昂凯生命科技(苏州)有限公司 | 用于预测肿瘤进展及预后的基因标志物组合、试剂盒及系统 |
| CN120380170A (zh) * | 2022-10-12 | 2025-07-25 | 液体活检研究有限责任公司 | 用于唾液中的前列腺癌检测的方法 |
| CN116298292B (zh) * | 2023-03-20 | 2023-09-08 | 江西省肿瘤医院(江西省第二人民医院、江西省癌症中心) | Gng2蛋白的检测试剂在制备诊断和预后结肠癌的产品中的用途 |
| WO2024206889A2 (en) * | 2023-03-31 | 2024-10-03 | The Board Of Regents Of The University Of Texas System | Microbiome as a biomarker for prostate cancer |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6351666B1 (en) | 1998-02-27 | 2002-02-26 | Biofield Corp. | Method and apparatus for sensing and processing biopotentials |
| US7353215B2 (en) | 2001-05-07 | 2008-04-01 | Health Discovery Corporation | Kernels and methods for selecting kernels for use in learning machines |
| US20050260572A1 (en) | 2001-03-14 | 2005-11-24 | Kikuya Kato | Method of predicting cancer |
| WO2003041562A2 (en) | 2001-11-14 | 2003-05-22 | Whitehead Institute For Biomedical Research | Molecular cancer diagnosis using tumor gene expression signature |
| EP1828917A4 (en) | 2004-11-12 | 2012-04-25 | Health Discovery Corp | BIOMARKERS FOR DETECTING, PREDICTING AND MONITORING PROSTATE DISEASE |
| US7914988B1 (en) | 2006-03-31 | 2011-03-29 | Illumina, Inc. | Gene expression profiles to predict relapse of prostate cancer |
| CN101720358A (zh) | 2007-02-23 | 2010-06-02 | 阿威亚拉德克斯股份有限公司 | 前列腺癌存活和复发 |
| WO2009067655A2 (en) | 2007-11-21 | 2009-05-28 | University Of Florida Research Foundation, Inc. | Methods of feature selection through local learning; breast and prostate cancer prognostic markers |
| CA3256492A1 (en) | 2010-01-11 | 2025-11-29 | Genomic Health Inc | Method to use gene expression to determine likelihood of clinical outcome of renal cancer |
| EP3812469A1 (en) | 2010-07-07 | 2021-04-28 | Myriad Genetics, Inc. | Gene signatures for cancer prognosis |
| US20140045915A1 (en) | 2010-08-31 | 2014-02-13 | The General Hospital Corporation | Cancer-related biological materials in microvesicles |
| US20150218646A1 (en) | 2012-07-20 | 2015-08-06 | Diagnocure Inc | Methods, kits and compositions for providing a clinical assessment of prostate cancer |
| ES2945036T3 (es) | 2012-08-16 | 2023-06-28 | Veracyte Sd Inc | Pronóstico del cáncer de próstata mediante biomarcadores |
| US20150329911A1 (en) | 2012-10-10 | 2015-11-19 | Institute Of Cancer Research: Royal Cancer Hospital | Nucleic acid biomarkers for prostate cancer |
| WO2014159443A1 (en) | 2013-03-14 | 2014-10-02 | Genomedx Biosciences, Inc. | Cancer biomarkers and classifiers and uses thereof |
| HK1219763A1 (zh) | 2013-03-15 | 2017-04-13 | Metamark Genetics, Inc. | 用於癌症预後的组合物和方法 |
| GB201320061D0 (en) * | 2013-11-13 | 2013-12-25 | Electrophoretics Ltd | Materials nad methods for diagnosis and prognosis of liver cancer |
| WO2017062505A1 (en) | 2015-10-05 | 2017-04-13 | Cedars-Sinai Medical Center | Method of classifying and diagnosing cancer |
-
2016
- 2016-10-05 GB GBGB1616912.0A patent/GB201616912D0/en not_active Ceased
-
2017
- 2017-10-05 US US16/339,463 patent/US11746380B2/en active Active
- 2017-10-05 EP EP17780101.6A patent/EP3523443B1/en active Active
- 2017-10-05 WO PCT/EP2017/075368 patent/WO2018065525A1/en not_active Ceased
- 2017-10-05 JP JP2019518269A patent/JP7365899B2/ja active Active
- 2017-10-05 AU AU2017341084A patent/AU2017341084B2/en active Active
- 2017-10-05 CA CA3038743A patent/CA3038743A1/en active Pending
-
2022
- 2022-09-15 JP JP2022147254A patent/JP7539443B2/ja active Active
-
2023
- 2023-07-05 US US18/347,074 patent/US20230349000A1/en active Pending
-
2024
- 2024-01-10 AU AU2024200150A patent/AU2024200150A1/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2019537108A5 (enExample) | ||
| US20240379190A1 (en) | Anomalous Fragment Detection and Classification | |
| US20210310075A1 (en) | Cancer Classification with Synthetic Training Samples | |
| EP2438187A1 (en) | miRNA FINGERPRINT IN THE DIAGNOSIS OF MULTIPLE SCLEROSIS | |
| EP3899952A1 (en) | Anomalous fragment detection and classification | |
| AU2025202052A1 (en) | Cancer classification with tissue of origin thresholding | |
| JP2012525818A (ja) | 腫瘍特性及びマーカーセットの同定のための方法、腫瘍分類、並びに癌のマーカーセット | |
| JP2020523991A (ja) | Ｐｒａｅｇｎａｎｔ転移性乳癌コホートにおける不良アウトカムの予後指標因子 | |
| CN116417143A (zh) | 肝细胞癌预后评估以及分子分型的方法、标志物及其应用 | |
| US20170233828A1 (en) | Glycosyltransferase gene expression profile to identify multiple cancer types and subtypes | |
| US20200294622A1 (en) | Subtyping of TNBC And Methods | |
| Malta et al. | Advances in central nervous system tumor classification | |
| Henry et al. | Use of gene-expression profiling to recommend adjuvant chemotherapy for breast cancer | |
| CN117413071A (zh) | 制备用于癌症诊断的多分析预测模型的方法 | |
| Anderson et al. | Predictive modeling of lung cancer recurrence using alternative splicing events versus differential expression data | |
| Gerashchenko et al. | Development of gene expression panels to determine prostate cancer | |
| Geetanjali et al. | Identifying Biomarkers for Papillary Thyroid Carcinoma Using Machine Learning | |
| Jordan | Are expression profiles meaningless for cancer studies? | |
| Tang et al. | Immune Cell as a Promising Biomarker in the Diagnosis and Prognosis of Cutaneous Melanoma by Using Machine Learning | |
| Choi et al. | Leveraging AI for facioscapulohumeral muscular dystrophy prediction and omics biomarker identification | |
| CN118043909A (zh) | 使用并行处理和整合随时间的未来拦截发病率对多癌症早期检测效果进行微观模拟 | |
| Arslan et al. | Gene arrays, prognosis, and therapeutic interventions | |
| CN116825367A (zh) | 一种组织硬度预测模型的建立、组织硬度预测方法及装置 | |
| Whipple et al. | A log likelihood predictor for genomic classification of oral cancer using principle component analysis for feature selection | |
| Yan | Selected topics in statistical methods for DNA microarray analysis |