JP2019533148A5 - - Google Patents
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- JP2019533148A5 JP2019533148A5 JP2019515484A JP2019515484A JP2019533148A5 JP 2019533148 A5 JP2019533148 A5 JP 2019533148A5 JP 2019515484 A JP2019515484 A JP 2019515484A JP 2019515484 A JP2019515484 A JP 2019515484A JP 2019533148 A5 JP2019533148 A5 JP 2019533148A5
- Authority
- JP
- Japan
- Prior art keywords
- item
- article
- janus
- janus droplets
- specimen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 description 21
- 239000012071 phase Substances 0.000 description 21
- 239000000126 substance Substances 0.000 description 18
- 239000000523 sample Substances 0.000 description 9
- 150000001875 compounds Chemical class 0.000 description 6
- 230000005670 electromagnetic radiation Effects 0.000 description 5
- 239000012472 biological sample Substances 0.000 description 4
- 230000005540 biological transmission Effects 0.000 description 4
- 150000001720 carbohydrates Chemical class 0.000 description 3
- 229920000642 polymer Polymers 0.000 description 3
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 2
- 108090000790 Enzymes Proteins 0.000 description 2
- 102000004190 Enzymes Human genes 0.000 description 2
- 239000002253 acid Substances 0.000 description 2
- 150000007513 acids Chemical class 0.000 description 2
- 235000014633 carbohydrates Nutrition 0.000 description 2
- 229930195733 hydrocarbon Natural products 0.000 description 2
- 150000002430 hydrocarbons Chemical class 0.000 description 2
- 239000002608 ionic liquid Substances 0.000 description 2
- 239000004973 liquid crystal related substance Substances 0.000 description 2
- 229920001296 polysiloxane Polymers 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- 229910019142 PO4 Inorganic materials 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 230000004523 agglutinating effect Effects 0.000 description 1
- 239000008346 aqueous phase Substances 0.000 description 1
- 229910002092 carbon dioxide Inorganic materials 0.000 description 1
- 239000001569 carbon dioxide Substances 0.000 description 1
- 239000003638 chemical reducing agent Substances 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 239000002131 composite material Substances 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003792 electrolyte Substances 0.000 description 1
- 239000002360 explosive Substances 0.000 description 1
- 229910021389 graphene Inorganic materials 0.000 description 1
- 239000002563 ionic surfactant Substances 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 229920002521 macromolecule Polymers 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 239000002736 nonionic surfactant Substances 0.000 description 1
- 102000039446 nucleic acids Human genes 0.000 description 1
- 108020004707 nucleic acids Proteins 0.000 description 1
- 150000007523 nucleic acids Chemical class 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 239000007800 oxidant agent Substances 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 235000021317 phosphate Nutrition 0.000 description 1
- 150000003013 phosphoric acid derivatives Chemical class 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 150000003871 sulfonates Chemical class 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
- 108700012359 toxins Proteins 0.000 description 1
- 239000002888 zwitterionic surfactant Substances 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15/269,543 US10060913B2 (en) | 2016-09-19 | 2016-09-19 | Systems including janus droplets capable of binding an analyte and changing orientation to provide a detectable change |
| US15/269,543 | 2016-09-19 | ||
| PCT/US2017/052209 WO2018053481A1 (en) | 2016-09-19 | 2017-09-19 | Detection of analytes with janus droplets |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019533148A JP2019533148A (ja) | 2019-11-14 |
| JP2019533148A5 true JP2019533148A5 (https=) | 2020-11-12 |
| JP7193147B2 JP7193147B2 (ja) | 2022-12-20 |
Family
ID=60084060
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019515484A Active JP7193147B2 (ja) | 2016-09-19 | 2017-09-19 | ヤヌス液滴を用いた検体の検出 |
Country Status (4)
| Country | Link |
|---|---|
| US (2) | US10060913B2 (https=) |
| EP (1) | EP3516393B1 (https=) |
| JP (1) | JP7193147B2 (https=) |
| WO (1) | WO2018053481A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20210041425A1 (en) * | 2014-10-31 | 2021-02-11 | Massachusetts Institute Of Technology | Complex liquid crystal droplets |
| US11119098B2 (en) | 2014-10-31 | 2021-09-14 | Massachusetts Institute Of Technology | Systems including Janus droplets |
| JP6914192B2 (ja) | 2014-10-31 | 2021-08-04 | マサチューセッツ インスティテュート オブ テクノロジー | 乳剤形成のための組成および方法 |
| US20190170737A1 (en) | 2016-09-19 | 2019-06-06 | Massachusetts Institute Of Technology | Systems including janus droplets |
| US11899013B2 (en) * | 2019-06-25 | 2024-02-13 | Canon Medical Systems Corporation | Method of detecting or quantifying detection target in specimen, composite particle, and reagent |
| US12274993B2 (en) | 2019-09-18 | 2025-04-15 | Massachusetts Institute Of Technology | Systems and methods for affecting interactions of electromagnetic radiation with janus droplets for sensitive detection of species |
| KR102795597B1 (ko) * | 2021-04-16 | 2025-04-15 | 장지환 | 야누스 입자 정렬을 이용한 진단 방법 및 진단장치 |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4870026A (en) * | 1982-09-16 | 1989-09-26 | The General Hospital Corporation | Non-A, non-B. hepatitis, virus, methods of identification purification, characterization, diagnosis and immunization |
| US4912034A (en) * | 1987-09-21 | 1990-03-27 | Biogenex Laboratories | Immunoassay test device and method |
| WO1992017179A1 (en) | 1991-03-28 | 1992-10-15 | Micro Vesicular Systems, Inc. | Lipid vesicle containing water-in-oil emulsions |
| US5332661A (en) * | 1991-07-31 | 1994-07-26 | Abbott Laboratories | Reagents and methods for the quantification of total doxepins in biological fluids |
| DE69223980T2 (de) * | 1991-10-15 | 1998-05-28 | Multilyte Ltd | Bindungstest unter benutzung eines markierten reagens |
| US5573994A (en) | 1994-05-13 | 1996-11-12 | University Of Cincinnati | Superabsorbent foams, and method for producing the same |
| US6180418B1 (en) * | 1998-01-20 | 2001-01-30 | The United States Of America As Represented By The Secretary Of The Navy | Force discrimination assay |
| DE60116303T2 (de) | 2000-06-05 | 2006-07-06 | Syngenta Ltd., Guildford | Neue emulsionen |
| US7625951B2 (en) | 2000-07-13 | 2009-12-01 | University Of Kentucky Research Foundation | Stimuli-responsive hydrogel microdomes integrated with genetically engineered proteins for high-throughput screening of pharmaceuticals |
| EP2275819B1 (en) * | 2000-10-19 | 2019-11-27 | Mycartis NV | Method for the manipulation of microcarriers for an identification purpose |
| JP3595805B2 (ja) | 2001-08-07 | 2004-12-02 | キヤノン株式会社 | 刺激応答性組成物、並びに該組成物を用いた画像形成方法および装置 |
| US7947772B2 (en) * | 2004-11-10 | 2011-05-24 | The Regents Of The University Of Michigan | Multiphasic nano-components comprising colorants |
| JP4690418B2 (ja) * | 2004-11-10 | 2011-06-01 | ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン | 多相ナノ粒子 |
| WO2007149310A2 (en) * | 2006-06-16 | 2007-12-27 | The Regents Of The University Of Michigan | Multiphasic biofunctional nano-components and methods for use thereof |
| US20090306311A1 (en) | 2008-06-05 | 2009-12-10 | The Administrators Of The Tulane Educational Fund | Methods and instrumentation for during-synthesis monitoring of polymer functional evolution |
| WO2009061372A1 (en) | 2007-11-02 | 2009-05-14 | President And Fellows Of Harvard College | Systems and methods for creating multi-phase entities, including particles and/or fluids |
| FR2927252B1 (fr) | 2008-02-12 | 2010-04-23 | Oreal | Emulsion huile-dans-eau contenant un polyere amphiphile |
| US20100069726A1 (en) * | 2008-06-04 | 2010-03-18 | Seventh Sense Biosystems, Inc. | Compositions and methods for rapid one-step diagnosis |
| US8278040B2 (en) | 2008-07-30 | 2012-10-02 | Wisconsin Alumni Research Foundation | Optically responsive and mechanically tunable colloid-in-liquid crystal gels |
| US20110052633A1 (en) | 2009-09-02 | 2011-03-03 | National Health Research Institutes | Multi-phase emulsions based on amphiphilic block copolymers |
| US20110104777A1 (en) * | 2009-11-03 | 2011-05-05 | Manuel Marquez | Method of making an artificial micro-gland that is anisotropic |
| US20120288852A1 (en) * | 2010-01-15 | 2012-11-15 | Richard Willson | Force Mediated Assays |
| PL219567B1 (pl) | 2010-01-29 | 2015-05-29 | Braster Spółka Z Ograniczoną Odpowiedzialnością | Ciekłokrystaliczna emulsja typu olej w wodzie i sposób wytwarzania ciekłokrystalicznej emulsji |
| WO2012075033A2 (en) | 2010-11-29 | 2012-06-07 | President And Fellows Of Harvard College | Environmentally responsive optical microstructured hybrid actuator assemblies and applications thereof |
| US9387446B2 (en) | 2011-09-22 | 2016-07-12 | Ariel-University Research And Development Company Ltd. | Emulsions and methods of making emulsions |
| WO2013059294A1 (en) * | 2011-10-17 | 2013-04-25 | The Regents Of The University Of Michigan | Methods and devices for detecting and separating target analyte species using anisotropic micro-particles |
| AU2014214682B2 (en) | 2013-02-08 | 2018-07-26 | 10X Genomics, Inc. | Polynucleotide barcode generation |
| US10285940B2 (en) | 2013-10-02 | 2019-05-14 | The Regents Of The University Of California | Multicomponent, internally structured nanoemulsions and methods of production |
| US9642923B2 (en) * | 2014-02-24 | 2017-05-09 | Verily Life Sciences Llc | Engineered particles with polarization contrast and alignment control for enhanced imaging |
| JP6914192B2 (ja) | 2014-10-31 | 2021-08-04 | マサチューセッツ インスティテュート オブ テクノロジー | 乳剤形成のための組成および方法 |
| WO2016070027A1 (en) | 2014-10-31 | 2016-05-06 | Massachusetts Institute Of Technology | Compositions and methods for arranging colloid phases |
-
2016
- 2016-09-19 US US15/269,543 patent/US10060913B2/en active Active
-
2017
- 2017-09-19 EP EP17784444.6A patent/EP3516393B1/en not_active Not-in-force
- 2017-09-19 JP JP2019515484A patent/JP7193147B2/ja active Active
- 2017-09-19 WO PCT/US2017/052209 patent/WO2018053481A1/en not_active Ceased
-
2018
- 2018-08-27 US US16/113,520 patent/US20190212333A1/en not_active Abandoned
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