JP2019527547A5 - - Google Patents

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Publication number
JP2019527547A5
JP2019527547A5 JP2019500446A JP2019500446A JP2019527547A5 JP 2019527547 A5 JP2019527547 A5 JP 2019527547A5 JP 2019500446 A JP2019500446 A JP 2019500446A JP 2019500446 A JP2019500446 A JP 2019500446A JP 2019527547 A5 JP2019527547 A5 JP 2019527547A5
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JP
Japan
Prior art keywords
polypeptide
seq
heteropolymer
amino acids
begins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
JP2019500446A
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English (en)
Japanese (ja)
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JP2019527547A (ja
JP7159148B2 (ja
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Priority claimed from PCT/US2017/040849 external-priority patent/WO2018009624A1/en
Publication of JP2019527547A publication Critical patent/JP2019527547A/ja
Priority to JP2022144508A priority Critical patent/JP2022172479A/ja
Publication of JP2019527547A5 publication Critical patent/JP2019527547A5/ja
Application granted granted Critical
Publication of JP7159148B2 publication Critical patent/JP7159148B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2019500446A 2016-07-07 2017-07-06 Ｔｇｆベータスーパーファミリーホモ多量体およびその使用 Active JP7159148B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2022144508A JP2022172479A (ja) 2016-07-07 2022-09-12 Ｔｇｆベータスーパーファミリーホモ多量体およびその使用

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662359614P 2016-07-07 2016-07-07
US62/359,614 2016-07-07
US201662404670P 2016-10-05 2016-10-05
US62/404,670 2016-10-05
PCT/US2017/040849 WO2018009624A1 (en) 2016-07-07 2017-07-06 Tgf-beta superfamily heteromultimers and uses thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2022144508A Division JP2022172479A (ja) 2016-07-07 2022-09-12 Ｔｇｆベータスーパーファミリーホモ多量体およびその使用

Publications (3)

Publication Number Publication Date
JP2019527547A JP2019527547A (ja) 2019-10-03
JP2019527547A5 true JP2019527547A5 (https=) 2022-09-22
JP7159148B2 JP7159148B2 (ja) 2022-10-24

Family

ID=60913181

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2019500446A Active JP7159148B2 (ja) 2016-07-07 2017-07-06 Ｔｇｆベータスーパーファミリーホモ多量体およびその使用
JP2022144508A Pending JP2022172479A (ja) 2016-07-07 2022-09-12 Ｔｇｆベータスーパーファミリーホモ多量体およびその使用

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2022144508A Pending JP2022172479A (ja) 2016-07-07 2022-09-12 Ｔｇｆベータスーパーファミリーホモ多量体およびその使用

Country Status (6)

Country Link
US (1) US20200071382A1 (https=)
EP (1) EP3481860A4 (https=)
JP (2) JP7159148B2 (https=)
AU (2) AU2017293778B2 (https=)
CA (1) CA3029890A1 (https=)
WO (1) WO2018009624A1 (https=)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10358476B2 (en) 2015-04-06 2019-07-23 Acceleron Pharma Inc. Single arm type I and type II receptor fusion proteins and uses thereof
MA41920B1 (fr) 2015-04-06 2021-05-31 Acceleron Pharma Inc Protéines de fusion de récepteur type i et type ii à bras unique et leurs utilisations
MA41919A (fr) 2015-04-06 2018-02-13 Acceleron Pharma Inc Hétéromultimères alk4:actriib et leurs utilisations
CA3039573A1 (en) 2016-10-05 2018-04-12 Acceleron Pharma Inc. Alk4:actriib heteromultimers and uses thereof
CN110036025B (zh) 2016-10-05 2024-03-22 阿塞勒隆制药公司 变体ActRIIB蛋白及其用途
US12103959B2 (en) 2018-05-03 2024-10-01 Acceleron Pharma Inc. Multispecific binders of TGFBeta-superfamily ligands and uses thereof
CA3103427A1 (en) * 2018-06-15 2019-12-19 Acceleron Pharma Inc. Bi-and tri-functional fusion proteins and uses thereof
US20220372135A1 (en) 2019-09-27 2022-11-24 Disc Medicine, Inc. Methods for treating myelofibrosis and related conditions
KR20230012539A (ko) 2020-05-13 2023-01-26 디스크 메디슨, 인크. 골수섬유증을 치료하기 위한 항-헤모주벨린 (hjv) 항체
JP2024540480A (ja) 2021-11-17 2024-10-31 ディスク・メディシン・インコーポレイテッド 腎臓疾患の貧血を処置する方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN2013MN01438A (https=) 2011-03-17 2015-06-12 Univ Ramot
JP6250533B2 (ja) * 2011-04-20 2017-12-20 アクセレロン ファーマ インコーポレイテッドＡｃｃｅｌｅｒｏｎ Ｐｈａｒｍａ，Ｉｎｃ． エンドグリンポリペプチドおよびその使用
US20140193425A1 (en) * 2012-10-05 2014-07-10 Acceleron Pharma, Inc. Treatment of cancer with alk1 antagonists
EP3851118A1 (en) * 2013-10-25 2021-07-21 Acceleron Pharma Inc. Endoglin peptides to treat fibrotic diseases
WO2015147908A1 (en) * 2014-03-28 2015-10-01 Acceleron Pharma, Inc. Use of activin receptor-like kinase 1 (alk-1) antagonists in the treatment of cancer
US20190202908A1 (en) 2014-04-15 2019-07-04 President And Fellows Of Harvard College Bi-specific agents

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