JP2019527547A5 - - Google Patents

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Publication number
JP2019527547A5
JP2019527547A5 JP2019500446A JP2019500446A JP2019527547A5 JP 2019527547 A5 JP2019527547 A5 JP 2019527547A5 JP 2019500446 A JP2019500446 A JP 2019500446A JP 2019500446 A JP2019500446 A JP 2019500446A JP 2019527547 A5 JP2019527547 A5 JP 2019527547A5
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JP
Japan
Prior art keywords
polypeptide
seq
heteropolymer
amino acids
begins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2019500446A
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English (en)
Japanese (ja)
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JP2019527547A (ja
JP7159148B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2017/040849 external-priority patent/WO2018009624A1/en
Publication of JP2019527547A publication Critical patent/JP2019527547A/ja
Priority to JP2022144508A priority Critical patent/JP2022172479A/ja
Publication of JP2019527547A5 publication Critical patent/JP2019527547A5/ja
Application granted granted Critical
Publication of JP7159148B2 publication Critical patent/JP7159148B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2019500446A 2016-07-07 2017-07-06 Tgfベータスーパーファミリーホモ多量体およびその使用 Expired - Fee Related JP7159148B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2022144508A JP2022172479A (ja) 2016-07-07 2022-09-12 Tgfベータスーパーファミリーホモ多量体およびその使用

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662359614P 2016-07-07 2016-07-07
US62/359,614 2016-07-07
US201662404670P 2016-10-05 2016-10-05
US62/404,670 2016-10-05
PCT/US2017/040849 WO2018009624A1 (en) 2016-07-07 2017-07-06 Tgf-beta superfamily heteromultimers and uses thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2022144508A Division JP2022172479A (ja) 2016-07-07 2022-09-12 Tgfベータスーパーファミリーホモ多量体およびその使用

Publications (3)

Publication Number Publication Date
JP2019527547A JP2019527547A (ja) 2019-10-03
JP2019527547A5 true JP2019527547A5 (enExample) 2022-09-22
JP7159148B2 JP7159148B2 (ja) 2022-10-24

Family

ID=60913181

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2019500446A Expired - Fee Related JP7159148B2 (ja) 2016-07-07 2017-07-06 Tgfベータスーパーファミリーホモ多量体およびその使用
JP2022144508A Pending JP2022172479A (ja) 2016-07-07 2022-09-12 Tgfベータスーパーファミリーホモ多量体およびその使用

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2022144508A Pending JP2022172479A (ja) 2016-07-07 2022-09-12 Tgfベータスーパーファミリーホモ多量体およびその使用

Country Status (6)

Country Link
US (1) US20200071382A1 (enExample)
EP (1) EP3481860A4 (enExample)
JP (2) JP7159148B2 (enExample)
AU (2) AU2017293778B2 (enExample)
CA (1) CA3029890A1 (enExample)
WO (1) WO2018009624A1 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3280435B1 (en) 2015-04-06 2021-06-02 Acceleron Pharma Inc. Tgf-beta superfamily type i and type ii receptor heteromultimers and uses thereof
MA41919A (fr) 2015-04-06 2018-02-13 Acceleron Pharma Inc Hétéromultimères alk4:actriib et leurs utilisations
CN113683708A (zh) 2015-04-06 2021-11-23 阿塞勒隆制药公司 单臂i型和ii型受体融合蛋白和其用途
AU2017338916B2 (en) 2016-10-05 2022-03-24 Acceleron Pharma Inc. Variant ActRIIB proteins and uses thereof
CN110678195A (zh) 2016-10-05 2020-01-10 阿塞勒隆制药公司 ALK4:ActRIIB异多聚体及其用途
AU2019262139A1 (en) * 2018-05-03 2020-11-26 Acceleron Pharma Inc. Multispecific binders of TGFβ-superfamily ligands and uses thereof
US20220089683A1 (en) * 2018-06-15 2022-03-24 Acceleron Pharma Inc. Bi-and tri-functional fusion proteins and uses thereof
CA3156007A1 (en) 2019-09-27 2021-04-01 Disc Medicine, Inc. METHODS OF TREATING MYELOFIBROSE AND ASSOCIATED CONDITIONS
AU2021273014A1 (en) 2020-05-13 2022-11-17 AbbVie Deutschland GmbH & Co. KG Anti-hemojuvelin (HJV) antibodies for treating anemia of chronic disease
ES3075793T3 (en) 2020-05-13 2026-08-07 Disc Medicine Inc Anti-hemojuvelin (hjv) antibodies for treating myelofibrosis
EP4433160A1 (en) 2021-11-17 2024-09-25 Disc Medicine, Inc. Methods for treating anemia of kidney disease
WO2026125668A1 (en) * 2024-12-13 2026-06-18 Institut National de la Santé et de la Recherche Médicale Peptide derived from endoglin for treating bleeding disorders

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2686348B1 (en) 2011-03-17 2015-12-30 Ramot at Tel-Aviv University Ltd. Bi- and monospecific, asymmetric antibodies and methods of generating the same
EP3549952A1 (en) * 2011-04-20 2019-10-09 Acceleron Pharma Inc. Endoglin polypeptides and uses thereof
WO2014055869A1 (en) 2012-10-05 2014-04-10 Acceleron Pharma, Inc. Treatment of cancer with alk1 antagonists
AU2014339898B2 (en) * 2013-10-25 2020-07-23 Acceleron Pharma, Inc. Endoglin peptides to treat fibrotic diseases
AU2014388308A1 (en) * 2014-03-28 2016-10-27 Acceleron Pharma, Inc. Use of activin receptor-like kinase 1 (ALK-1) antagonists in the treatment of cancer
WO2015160940A1 (en) 2014-04-15 2015-10-22 President And Fellows Of Harvard College Bi-specific agents

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