JP2019526792A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2019526792A5 JP2019526792A5 JP2019508836A JP2019508836A JP2019526792A5 JP 2019526792 A5 JP2019526792 A5 JP 2019526792A5 JP 2019508836 A JP2019508836 A JP 2019508836A JP 2019508836 A JP2019508836 A JP 2019508836A JP 2019526792 A5 JP2019526792 A5 JP 2019526792A5
- Authority
- JP
- Japan
- Prior art keywords
- thiol
- ligand
- target molecule
- reaction mixture
- reaction
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1614152.5A GB201614152D0 (en) | 2016-08-18 | 2016-08-18 | Assay |
| GB1614152.5 | 2016-08-18 | ||
| PCT/GB2017/052456 WO2018033753A2 (en) | 2016-08-18 | 2017-08-18 | Assay |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019526792A JP2019526792A (ja) | 2019-09-19 |
| JP2019526792A5 true JP2019526792A5 (enExample) | 2020-09-24 |
| JP7008688B2 JP7008688B2 (ja) | 2022-02-10 |
Family
ID=57045465
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019508836A Active JP7008688B2 (ja) | 2016-08-18 | 2017-08-18 | アッセイ |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US11415579B2 (enExample) |
| EP (1) | EP3500858B1 (enExample) |
| JP (1) | JP7008688B2 (enExample) |
| ES (1) | ES2972584T3 (enExample) |
| GB (1) | GB201614152D0 (enExample) |
| WO (1) | WO2018033753A2 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112121052B (zh) * | 2019-06-25 | 2024-10-22 | 复旦大学 | 丙烯酰基苯并氮杂䓬类化合物在制备防治血液肿瘤药物中的用途 |
| CN113387831A (zh) * | 2020-03-11 | 2021-09-14 | 苏州大学 | 酰胺类化合物及其在制备神经炎症抑制剂中的应用 |
| JP2023548079A (ja) * | 2020-10-28 | 2023-11-15 | ジェネンテック， インコーポレイテッド | 遊離チオール検出のための蛍光エルマンアッセイ |
| JP7667684B2 (ja) * | 2021-04-06 | 2025-04-23 | 株式会社日立製作所 | 検体の分析前処理方法および検体前処理装置 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6335155B1 (en) | 1998-06-26 | 2002-01-01 | Sunesis Pharmaceuticals, Inc. | Methods for rapidly identifying small organic molecule ligands for binding to biological target molecules |
| JP3836791B2 (ja) | 2000-11-21 | 2006-10-25 | サネシス ファーマシューティカルズ， インコーポレイテッド | リガンドの迅速な同定のための拡張されたテザー化アプローチ |
| US6887667B2 (en) * | 2000-12-28 | 2005-05-03 | Alfred E. Mann Institute For Biomedical Engineering At The University Of Southern California | Method and apparatus to identify small variations of biomolecules |
| US7672786B2 (en) * | 2003-07-02 | 2010-03-02 | Sergey Krylov | Non-equilibrium capillary electrophoresis of equilibrium mixtures (NECEEM)—based methods for drug and diagnostic development |
| WO2005034840A2 (en) | 2003-09-17 | 2005-04-21 | Sunesis Pharmaceuticals, Inc. | Identification of kinase inhibitors |
-
2016
- 2016-08-18 GB GBGB1614152.5A patent/GB201614152D0/en not_active Ceased
-
2017
- 2017-08-18 WO PCT/GB2017/052456 patent/WO2018033753A2/en not_active Ceased
- 2017-08-18 EP EP17758261.6A patent/EP3500858B1/en active Active
- 2017-08-18 US US16/326,298 patent/US11415579B2/en active Active
- 2017-08-18 ES ES17758261T patent/ES2972584T3/es active Active
- 2017-08-18 JP JP2019508836A patent/JP7008688B2/ja active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2019526792A5 (enExample) | ||
| Pettinger et al. | Lysine‐targeting covalent inhibitors | |
| Mah et al. | Drug discovery considerations in the development of covalent inhibitors | |
| Goodwin et al. | In silico predictions of blood-brain barrier penetration: considerations to “keep in mind” | |
| Khamis et al. | Comparative assessment of machine-learning scoring functions on PDBbind 2013 | |
| Ballester | Selecting machine-learning scoring functions for structure-based virtual screening | |
| Chojnacki et al. | Polyubiquitin-photoactivatable crosslinking reagents for mapping ubiquitin interactome identify Rpn1 as a proteasome ubiquitin-associating subunit | |
| JP2016527486A5 (enExample) | ||
| Troelsen et al. | Library design strategies to accelerate fragment‐based drug discovery | |
| JP2009521215A5 (enExample) | ||
| Cascales et al. | Binding of glutamate to the umami receptor | |
| Fornes et al. | On the use of knowledge-based potentials for the evaluation of models of protein–protein, protein–DNA, and protein–RNA interactions | |
| CN109313184A (zh) | 用于治疗性抗体表征的基于阵列的肽文库 | |
| JP7008688B2 (ja) | アッセイ | |
| Knight et al. | Impacting drug discovery projects with large-scale enumerations, machine learning strategies, and free-energy predictions | |
| Liu et al. | Advances in mass spectrometry-based epitope mapping of protein therapeutics | |
| Reese et al. | How far does a receptor influence vibrational properties of an odorant? | |
| Yao et al. | Parameter estimation and uncertainty quantification of rainfall-runoff models using data assimilation methods based on deep learning and local ensemble updates | |
| Linnankoski et al. | Passive oral drug absorption can be predicted more reliably by experimental than computational models—fact or myth | |
| EP2795498B1 (en) | Method of binding site and binding energy determination by mixed explicit solvent simulations | |
| Arrad et al. | Modeling the binary system Mn (NO3) 2–H2O with the extended universal quasichemical (UNIQUAC) model | |
| US20190034580A1 (en) | Methods for improved arrays or libraries using normalization strategies based on molecular structure | |
| Wolter et al. | Ligand photo-isomerization triggers conformational changes in iGluR2 ligand binding domain | |
| JP2006030037A5 (enExample) | ||
| Habicht et al. | Fitting error vs parameter performance─ how to choose reliable PC-SAFT pure-component parameters by physics-informed machine learning |