JP2019520560A - マイクロ流体装置 - Google Patents
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Abstract
Description
Claims (15)
- マイクロ流体装置であって、
チャンネルと、
前記チャンネルと流体連絡するホワイエであって、前記チャンネルは、該ホワイエよりも幅が狭いことからなる、ホワイエと、
前記チャンネルを通る流体の特性を検出するためのセンサーと、
前記ホワイエと流体連絡するノズルと、
前記ノズルに沿って配置されたアクチュエータと、
前記流体の前記検出された特性が所定の条件を満たすか否かを判定し、及び前記流体の前記検出された特性が前記所定の条件を満たすことに応答して、所定のアクションを実行するためのコントローラ
を備えるマイクロ流体装置。 - 前記所定のアクションが、
前記ホワイエ内に含まれている前記流体の供給場所を変えることと、
前記ホワイエ内に含まれている前記流体と別のホワイエ内に含まれている別の流体を供給する順番を変えることと、
井戸内に供給される流体の量を変えることと、
前記流体が供給された井戸に第2の流体を供給することと、
前記流体の前記検出された特性が前記所定の条件を満たすと判定した後の特定の時点で前記第2の流体を供給すること
とのうちの少なくとも1つを含むことからなる、請求項1のマイクロ流体装置。 - 前記コントローラは、前記ホワイエ内に含まれている前記流体に適用される供給プロトコルを変更することによって、前記所定のアクションを実行することができる、請求項1のマイクロ流体装置。
- 前記流体の前記特性は、前記流体の導電率である、請求項1のマイクロ流体装置。
- 前記流体の前記特性は、該流体に含まれている所定のタイプの粒子である、請求項1のマイクロ流体装置。
- 第2の流体を含む第2のホワイエと、
第2のノズルと、
第2のアクチュエータ
をさらに備え、
前記コントローラは、前記流体の前記検出された特性が前記所定の条件を満たすことに応答して、前記第2のホワイエ内の第2の流体を前記第2のノズルを通して供給させるように前記第2のアクチュエータを作動させることができる、請求項1のマイクロ流体装置。 - 複数の井戸を含む基板をさらに備え、
前記コントローラは、前記流体の前記検出された特性が前記所定の条件を満たすことに応答して、前記ホワイエ内の流体を、前記ノズルを通して、前記複数の井戸のうちの第1の井戸に供給させるように前記アクチュエータを制御することができ、及び、前記流体の前記検出された特性が前記所定の条件を満たさないことに応答して、前記ホワイエ内の流体を、前記ノズルを通して、前記複数の井戸のうちの第2の井戸に供給させるように前記アクチュエータを制御することができることからなる、請求項1のマイクロ流体装置。 - マイクロ流体デバイスのチャンネルにおいて、該マイクロ流体デバイスのホワイエ内へと該チャンネルを通過する流体の特性を検出するステップと、
前記流体の前記検出された特性が、所定の条件を満たすか否かを判定するステップと、
前記流体の前記検出された特性が前記所定の条件を満たすという判定に応答して、前記ホワイエ内に含まれている前記流体に対して所定のアクションを実行するステップ
を含む方法。 - 前記ホワイエ内に含まれている前記流体に対して所定のアクションを実行する前記ステップがさらに、
前記ホワイエ内に含まれている前記流体の供給場所を変えることと、
前記ホワイエ内に含まれている前記流体と別のホワイエ内に含まれている別の流体を供給する順番を変えることと、
井戸内に供給される流体の量を変えることと、
前記流体が供給された井戸に第2の流体を供給することと、
前記流体の前記検出された特性が前記所定の条件を満たすと判定した後の特定の時点で前記第2の流体を供給すること
とのうちの少なくとも1つを含むことからなる、請求項8の方法。 - 前記ホワイエ内へと前記チャンネルを通過する前記流体の前記特性を検出する前記ステップがさらに、前記チャンネルを通過する前記流体の導電率を検出することを含む、請求項8の方法。
- 前記ホワイエ内へと前記チャンネルを通過する前記流体の前記特性を検出する前記ステップがさらに、前記チャンネルを通過する前記流体中の粒子の電気信号を検出することを含む、請求項8の方法。
- 前記流体の前記検出された特性が前記所定の条件を満たすとの判定に応答して第2のアクチュエータを作動させるステップをさらに含み、該第2のアクチュエータの作動によって、第2のホワイエ内に含まれている第2の流体が第2のノズルを通して供給されることからなる、請求項8の方法。
- 複数のマイクロ流体デバイスと、
コントローラ
を備えるマイクロ流体システムであって、
前記複数のマイクロ流体デバイスの各々は、
ホワイエであって、該ホワイエよりも断面積が小さいチャンネルと流体連絡するホワイエと、
前記ホワイエ内へと前記チャンネルを通過する流体の特性を検出するためのセンサーと、
前記ホワイエと流体連絡するノズルと、
前記ノズルに沿って配置されたアクチュエータ
を備え、
前記コントローラは、前記チャンネルを通過する前記流体の前記検出された特性に基づいて、前記複数のマイクロ流体デバイスに適用される供給プロトコルを変更することからなる、マイクロ流体システム。 - 前記コントローラは、
前記ホワイエ内に含まれている前記流体の供給場所を変えることと、
前記ホワイエ内に含まれている前記流体と別のホワイエ内に含まれている別の流体を供給する順番を変えることと、
井戸内に供給される流体の量を変えることと、
前記流体が供給された井戸に第2の流体を供給することと、
前記流体の前記検出された特性が前記所定の条件を満たすと判定した後の特定の時点で前記第2の流体を供給すること
とのうちの少なくとも1つによって前記供給プロトコルを変更することができることからなる、請求項13の流体供給システム。 - 前記コントローラはさらに、前記複数のマイクロ流体デバイスのうちの第2のマイクロ流体デバイスのチャンネルを通過する流体の前記検出された特性が所定の条件を満たすとの判定に応答して、前記複数のマイクロ流体デバイスのうちの第1のマイクロ流体デバイスの前記アクチュエータを作動させることができる、請求項13の流体供給システム。
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PCT/US2016/044097 WO2018022025A1 (en) | 2016-07-26 | 2016-07-26 | Microfluidic apparatuses |
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US (1) | US11203017B2 (ja) |
EP (1) | EP3427035B1 (ja) |
JP (1) | JP2019520560A (ja) |
CN (1) | CN109313117B (ja) |
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WO (1) | WO2018022025A1 (ja) |
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US11680957B2 (en) * | 2018-02-12 | 2023-06-20 | Hewlett-Packard Development Company, L.P. | Microfluidic flow sensor |
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WO2018022025A1 (en) | 2018-02-01 |
CN109313117B (zh) | 2022-01-14 |
US11203017B2 (en) | 2021-12-21 |
EP3427035A4 (en) | 2019-05-08 |
EP3427035A1 (en) | 2019-01-16 |
EP3427035B1 (en) | 2023-08-30 |
BR112018074178A2 (pt) | 2019-03-06 |
CN109313117A (zh) | 2019-02-05 |
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