JP2019520061A - Ｔ細胞の増殖 - Google Patents

Ｔ細胞の増殖 Download PDF

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JP2019520061A
JP2019520061A JP2018562017A JP2018562017A JP2019520061A JP 2019520061 A JP2019520061 A JP 2019520061A JP 2018562017 A JP2018562017 A JP 2018562017A JP 2018562017 A JP2018562017 A JP 2018562017A JP 2019520061 A JP2019520061 A JP 2019520061A
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cells
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culture
population
virus
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JP2019520061A5 (cg-RX-API-DMAC10.html
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ワン，ピーター
ウー，チュンシャオ
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テッサ・セラピューティクス・プライベート・リミテッド
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
    • C12N5/0638—Cytotoxic T lymphocytes [CTL] or lymphokine activated killer cells [LAK]
    • A—HUMAN NECESSITIES
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    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
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    • A61K40/00—Cellular immunotherapy
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    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
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    • A61K40/46—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515—Animal cells
    • A61K2039/5154—Antigen presenting cells [APCs], e.g. dendritic cells or macrophages
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515—Animal cells
    • A61K2039/5158—Antigen-pulsed cells, e.g. T-cells
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    • C12N2500/00—Specific components of cell culture medium
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/23—Interleukins [IL]
    • C12N2501/2302—Interleukin-2 (IL-2)
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    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/11—Coculture with; Conditioned medium produced by blood or immune system cells
    • C12N2502/1107—B cells
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    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/99—Coculture with; Conditioned medium produced by genetically modified cells
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    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

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  • Health & Medical Sciences (AREA)
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  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
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  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
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  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Virology (AREA)
  • Cell Biology (AREA)
  • Mycology (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Developmental Biology & Embryology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
JP2018562017A 2016-05-24 2016-10-25 Ｔ細胞の増殖 Pending JP2019520061A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662340605P 2016-05-24 2016-05-24
US62/340,605 2016-05-24
US15/290,230 2016-10-11
US15/290,230 US10052372B2 (en) 2016-05-24 2016-10-11 T cell expansion
PCT/EP2016/075644 WO2017202478A1 (en) 2016-05-24 2016-10-25 T cell expansion

Publications (2)

Publication Number Publication Date
JP2019520061A true JP2019520061A (ja) 2019-07-18
JP2019520061A5 JP2019520061A5 (cg-RX-API-DMAC10.html) 2019-11-14

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JP2018562017A Pending JP2019520061A (ja) 2016-05-24 2016-10-25 Ｔ細胞の増殖

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US (2) US10052372B2 (cg-RX-API-DMAC10.html)
EP (1) EP3265555B1 (cg-RX-API-DMAC10.html)
JP (1) JP2019520061A (cg-RX-API-DMAC10.html)
KR (1) KR20190013831A (cg-RX-API-DMAC10.html)
CN (1) CN109563483A (cg-RX-API-DMAC10.html)
DK (1) DK3265555T3 (cg-RX-API-DMAC10.html)
ES (1) ES2742215T3 (cg-RX-API-DMAC10.html)
HK (1) HK1250378B (cg-RX-API-DMAC10.html)
PT (1) PT3265555T (cg-RX-API-DMAC10.html)
SG (1) SG11201810471YA (cg-RX-API-DMAC10.html)
TW (1) TWI660970B (cg-RX-API-DMAC10.html)
WO (1) WO2017202478A1 (cg-RX-API-DMAC10.html)

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ES2972227T3 (es) * 2012-03-20 2024-06-11 Eagle Pharmaceuticals Inc Formulaciones de bendamustina
JP6987080B2 (ja) 2016-05-05 2021-12-22 サウスウェスト リサーチ インスティテュート 細胞増殖のための三次元バイオリアクター及び関連用途
US10052372B2 (en) * 2016-05-24 2018-08-21 Tessa Therapeutics Pte Ltd T cell expansion
KR102150371B1 (ko) * 2017-05-06 2020-09-01 엘지전자 주식회사 무선 통신 시스템에서 단말의 d2d 동작 방법 및 상기 방법을 이용하는 단말
EP3723774A4 (en) * 2017-12-15 2021-09-08 The Board of Trustees of the Leland Stanford Junior University COMPOSITIONS AND METHODS OF INHIBITION OF T-CELL EXHAUSTATION
US11149244B2 (en) 2018-04-04 2021-10-19 Southwest Research Institute Three-dimensional bioreactor for T-cell activation and expansion for immunotherapy
US11447731B2 (en) 2018-09-24 2022-09-20 Southwest Research Institute Three-dimensional bioreactors
WO2021221927A1 (en) 2020-04-27 2021-11-04 Parsons Corporation Narrowband iq signal obfuscation
WO2022197933A1 (en) 2021-03-18 2022-09-22 The Broad Institute, Inc. Compositions and methods for characterizing lymphoma and related conditions
JP2024515803A (ja) 2021-04-27 2024-04-10 ベイラー カレッジ オブ メディスン キメラ抗原受容体を発現するウイルス特異的免疫細胞
EP4422787A1 (en) 2021-10-28 2024-09-04 Southwest Research Institute Devices for cell separation
TW202346576A (zh) 2022-04-13 2023-12-01 新加坡商泰莎治療有限公司 治療性t細胞產品

Citations (1)

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WO2013133297A1 (ja) * 2012-03-07 2013-09-12 国立大学法人富山大学 T細胞の刺激方法およびその利用

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US5962318A (en) * 1996-11-15 1999-10-05 St. Jude Children's Research Hospital Cytotoxic T lymphocyte-mediated immunotherapy
AU1220599A (en) 1997-11-14 1999-06-07 Hemosol Inc. Method for the production and use of dendritic cells
WO2003012085A1 (en) * 2001-07-30 2003-02-13 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Antigen presenting cells, method for their preparation and their use for cancer vaccines
US7651855B2 (en) * 2003-04-17 2010-01-26 The Trustees Of The University Of Pennsylvania Regulatory T cells and their use in immunotherapy and suppression of autoimmune responses
WO2011072088A2 (en) * 2009-12-08 2011-06-16 Wilson Wolf Manufacturing Corporation Improved methods of cell culture for adoptive cell therapy
BR112014014591A8 (pt) * 2011-12-12 2017-07-04 Baylor College Medicine processo para a expansão in vitro de células t específicas de antígeno, produto de células t autólogas ou alogênicas expandidas, composição farmacêutica, e, método de tratamento de um paciente, e, usos de uma linhagem de células engenheirada, de células dendríticas pulsadas com misturas de antígeno-peptídeo, de t-apcs pulsadas com misturas de antígeno-peptídeo/peptídeo, e de misturas de antígeno-peptídeo com pbmcs
US10052372B2 (en) * 2016-05-24 2018-08-21 Tessa Therapeutics Pte Ltd T cell expansion

Patent Citations (2)

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Publication number Priority date Publication date Assignee Title
WO2013133297A1 (ja) * 2012-03-07 2013-09-12 国立大学法人富山大学 T細胞の刺激方法およびその利用
EP2824182A1 (en) * 2012-03-07 2015-01-14 National University Corporation University Of Toyama Method for stimulating t cell and use thereof

Non-Patent Citations (1)

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Publication number Publication date
KR20190013831A (ko) 2019-02-11
DK3265555T3 (da) 2019-08-12
US20170028042A1 (en) 2017-02-02
US10052372B2 (en) 2018-08-21
CN109563483A (zh) 2019-04-02
EP3265555A1 (en) 2018-01-10
HK1250378B (en) 2020-05-08
TW201741330A (zh) 2017-12-01
PT3265555T (pt) 2019-09-04
SG11201810471YA (en) 2018-12-28
EP3265555B1 (en) 2019-05-22
US20190269768A1 (en) 2019-09-05
TWI660970B (zh) 2019-06-01
WO2017202478A1 (en) 2017-11-30
ES2742215T3 (es) 2020-02-13

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