JP2019515886A - 病原体結合を減少させるための局所用組成物 - Google Patents
病原体結合を減少させるための局所用組成物 Download PDFInfo
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Abstract
Description
本願は、全体の開示が参照により本明細書中に組み込まれる、「TOPICAL COMPOSITION FOR REDUCING PATHOGEN BINDING」という題名であり、2016年3月31日提出の、米国仮特許出願第62/315,943号明細書に対する優先権および利益を主張する。
スタフィロコッカス・アウレウス(Staphylococcus aureus)
エシェリキア・コリ(Escherichia coli)
サルモネラ・チフィムリウム(Salmonella Typhimurium)
Claims (31)
- 表面上での病原体結合を減少させるための局所用組成物であって、
有効成分と、
少なくとも1つの担体と、を含み、前記有効成分が、プレバイオティクス物質、プロバイオティクス物質およびシンバイオティクス物質のうちの1つ以上を含み、前記局所用組成物が、表面上の病原体結合を統計学的に有意な量、減少させる、局所用組成物。 - 前記1つ以上のプレバイオティクスが、糖、オリゴフルクトース、ポリデキストロース、糖アルコール、グルカン、マンナンおよびイヌリンのうち少なくとも1つを含む、請求項1に記載の局所用組成物。
- 前記糖が、フルクトオリゴ糖およびガラクトオリゴ糖のうち少なくとも1つである、請求項2に記載の局所用組成物。
- 前記有効成分が、フルクトオリゴ糖とイヌリンとの混合物を含む、請求項1に記載の局所用組成物。
- 前記プロバイオティクス物質が、細菌、細菌由来物、酵母および真菌のうちの1つ以上を含む、請求項1に記載の局所用組成物。
- 前記細菌が、ラクトバチルス、ストレプトコッカス、エシェリキア、コリネバクテリウム、ラクトコッカス、エンテロコッカス、フソバクテリウム、ストレプトミセス、ロイコノストック、ミクロコッカス、ビフィドバクテリウム、プロピオニバクテリウム、ペディオコッカス、スタフィロコッカスおよびバチルスのうち1つ以上を含む、請求項5に記載の局所用組成物。
- 前記有効成分が、α−グルコ−オリゴ糖、フルクト−オリゴ糖および不活性化ラクトバチルスを含む、請求項1に記載の局所用組成物。
- 前記有効成分がバチルス発酵物である、請求項1に記載の局所用組成物。
- 前記担体が、ベース洗浄剤、清浄剤、セラムおよびローションのうち1つ以上を含む、請求項1に記載の局所用組成物。
- 前記表面が皮膚である、請求項1に記載の局所用組成物。
- 前記局所用組成物が0.005〜10重量%の有効成分を含む、請求項1に記載の局所用組成物。
- 前記局所用組成物が約1.0〜5.0重量%の有効成分を含む、請求項1に記載の局所用組成物。
- 前記局所用組成物の適用によって、表面上の病原体結合が少なくとも5%減少する、請求項1に記載の局所用組成物。
- 前記局所用組成物の適用によって、表面上の病原体結合が少なくとも10%減少する、請求項1に記載の局所用組成物。
- 表面上での病原体結合を減少させる方法であって、前記方法は、
洗浄剤および清浄剤のうち少なくとも1つで表面を洗浄することと、
前記表面に局所用組成物を塗布することであって、前記局所用組成物が、有効成分と、少なくとも1つの担体とから構成され、前記有効成分が、プレバイオティクス物質、プロバイオティクス物質およびシンバイオティクス物質のうちの1つ以上を含み、前記局所用組成物の塗布によって、表面上の病原体結合を統計学的に有意な量、減少させて、塗布することと、
のステップを含む方法。 - 前記表面が皮膚である、請求項15に記載の方法。
- 前記プレバイオティクス物質が、糖、オリゴフルクトース、ポリデキストロース、糖アルコール、グルカン、マンナンおよびイヌリンのうち少なくとも1つを含む、請求項15に記載の方法。
- 前記糖が、フルクトオリゴ糖およびガラクトオリゴ糖のうち少なくとも1つである、請求項17に記載の方法。
- 前記局所用組成物が、フルクトオリゴ糖とイヌリンとの混合物を含む、請求項15に記載の方法。
- 前記プロバイオティクス物質が、細菌、細菌由来物、酵母および真菌のうちの1つ以上を含む、請求項15に記載の方法。
- 前記細菌が、ラクトバチルス、ストレプトコッカス、エシェリキア、ラクトコッカス、エンテロコッカス、コリネバクテリウム、フソバクテリウム、ストレプトミセス、ロイコノストック、ミクロコッカス、ビフィドバクテリウム、プロピオニバクテリウム、ペディオコッカス、スタフィロコッカスおよびバチルスのうち1つ以上を含む、請求項20に記載の方法。
- 前記有効成分が、α−グルコ−オリゴ糖、フルクト−オリゴ糖および不活性化ラクトバチルスを含む、請求項15に記載の方法。
- 前記有効成分が、イヌリンとフルクト−オリゴ糖とのブレンド物を含む、請求項15に記載の方法。
- 前記有効成分が、バチルス発酵物である、請求項15に記載の方法。
- 前記担体が、ベース洗浄剤、清浄剤、セラムおよびローションのうち1つ以上を含む、請求項15に記載の方法。
- 前記担体が、清浄剤であり、アルコール含量50〜80重量%である、請求項25に記載の方法。
- 前記局所用組成物のpHが2.5〜9.0である、請求項15に記載の方法。
- 前記局所用組成物が、0.005〜10重量%の有効成分を含む、請求項15に記載の方法。
- 前記局所用組成物が、1.0〜5.0重量%の有効成分を含む、請求項28に記載の方法。
- 前記局所用組成物の適用によって、表面上の病原体結合が少なくとも5%減少する、請求項15に記載の方法。
- 前記局所用組成物の適用によって、表面上の病原体結合が少なくとも10%減少する、請求項15に記載の方法。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
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US201662315943P | 2016-03-31 | 2016-03-31 | |
US62/315,943 | 2016-03-31 | ||
PCT/US2017/025329 WO2017173244A1 (en) | 2016-03-31 | 2017-03-31 | Topical composition for reducing pathogen binding |
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Publication Number | Publication Date |
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JP2019515886A true JP2019515886A (ja) | 2019-06-13 |
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JP2018550595A Pending JP2019515886A (ja) | 2016-03-31 | 2017-03-31 | 病原体結合を減少させるための局所用組成物 |
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US (1) | US20170281660A1 (ja) |
EP (1) | EP3436028A1 (ja) |
JP (1) | JP2019515886A (ja) |
AU (1) | AU2017240656A1 (ja) |
CA (1) | CA3019127A1 (ja) |
WO (1) | WO2017173244A1 (ja) |
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EP3436028A1 (en) | 2019-02-06 |
CA3019127A1 (en) | 2017-10-05 |
WO2017173244A1 (en) | 2017-10-05 |
AU2017240656A1 (en) | 2018-11-15 |
US20170281660A1 (en) | 2017-10-05 |
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