JP2019512006A5 - - Google Patents
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- JP2019512006A5 JP2019512006A5 JP2018541254A JP2018541254A JP2019512006A5 JP 2019512006 A5 JP2019512006 A5 JP 2019512006A5 JP 2018541254 A JP2018541254 A JP 2018541254A JP 2018541254 A JP2018541254 A JP 2018541254A JP 2019512006 A5 JP2019512006 A5 JP 2019512006A5
- Authority
- JP
- Japan
- Prior art keywords
- peg
- pla
- poly
- dbco
- conh2
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662293609P | 2016-02-10 | 2016-02-10 | |
| US62/293,609 | 2016-02-10 | ||
| US201662369590P | 2016-08-01 | 2016-08-01 | |
| US62/369,590 | 2016-08-01 | ||
| PCT/US2016/047807 WO2017138983A1 (en) | 2016-02-10 | 2016-08-19 | Therapeutic nanoparticles having egfr ligands and methods of making and using same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019512006A JP2019512006A (ja) | 2019-05-09 |
| JP2019512006A5 true JP2019512006A5 (https=) | 2019-09-19 |
Family
ID=59496509
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018541254A Pending JP2019512006A (ja) | 2016-02-10 | 2016-08-19 | Ｅｇｆｒリガンドを有する治療用ナノ粒子ならびにその作製および使用方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US10137088B2 (https=) |
| EP (1) | EP3413917A4 (https=) |
| JP (1) | JP2019512006A (https=) |
| CN (1) | CN108697815A (https=) |
| AU (1) | AU2016392719A1 (https=) |
| CA (1) | CA3013896A1 (https=) |
| WO (1) | WO2017138983A1 (https=) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20140041505A (ko) | 2011-04-29 | 2014-04-04 | 셀렉타 바이오사이언시즈, 인크. | 조절 b 세포 유도를 위한 관용원성 합성 나노운반체 |
| HUE052599T2 (hu) | 2013-05-03 | 2021-05-28 | Selecta Biosciences Inc | CD4+ szabályozó T-sejtek fokozására szolgáló eljárások és készítmények |
| AU2015311704B2 (en) | 2014-09-07 | 2021-12-09 | Selecta Biosciences, Inc. | Methods and compositions for attenuating gene editing anti-viral transfer vector immune responses |
| US11951165B2 (en) | 2016-12-30 | 2024-04-09 | Vaxcyte, Inc. | Conjugated vaccine carrier proteins |
| ES3024474T3 (en) | 2016-12-30 | 2025-06-04 | Vaxcyte Inc | Polypeptide-antigen conjugates with non-natural amino acids |
| WO2018169811A1 (en) | 2017-03-11 | 2018-09-20 | Selecta Biosciences, Inc. | Methods and compositions related to combined treatment with anti-inflammatories and synthetic nanocarriers comprising an immunosuppressant |
| CN109966780B (zh) * | 2019-03-21 | 2021-03-09 | 浙江工商大学 | 一种水生贝类蒸煮汤中功能性纳米颗粒的分离方法 |
| CN114207440A (zh) | 2019-06-04 | 2022-03-18 | 西莱克塔生物科技公司 | 聚乙二醇化尿酸酶的制剂和剂量 |
| AU2021236234A1 (en) * | 2020-03-11 | 2022-10-06 | Selecta Biosciences, Inc. | Methods and compositions related to synthetic nanocarriers |
| US20230310647A1 (en) * | 2020-08-19 | 2023-10-05 | The Trustees Of The University Of Pennsylvania | Targeting cartilage egfr pathway for osteoarthritis treatment |
| CN114133432B (zh) * | 2021-11-01 | 2023-06-16 | 暨南大学 | 一种抑制肿瘤细胞生长和转移的靶向肽及其应用 |
| WO2023079677A1 (ja) * | 2021-11-05 | 2023-05-11 | 日本電信電話株式会社 | 分子拡散評価方法およびシステム |
| CA3237153A1 (en) | 2021-11-05 | 2023-05-11 | Targimmune Therapeutics Ag | Targeted linear conjugates comprising polyethyleneimine and polyethylene glycol and polyplexes comprising the same |
| CN114813998B (zh) * | 2022-03-24 | 2023-05-23 | 天津键凯科技有限公司 | 一种聚合物的检测方法 |
| CN115006390B (zh) * | 2022-06-27 | 2024-04-19 | 国药集团动物保健股份有限公司 | 一种病毒减毒制剂、其制备方法以及应用 |
| CN115317515B (zh) * | 2022-07-19 | 2024-08-20 | 沈阳药科大学 | 氯尼达明/牛血清白蛋白/磷酸铁多效协同仿生矿化纳米制剂及制备方法和应用 |
| KR20250105420A (ko) | 2022-11-07 | 2025-07-08 | 타르그이뮨 테라퓨틱스 아게 | 핵산 및 폴리에틸렌이민 및 폴리에틸렌 글리콜을 포함하는 표적화된 컨쥬게이트의 다중복합체 |
| EP4615511A1 (en) | 2022-11-07 | 2025-09-17 | TargImmune Therapeutics AG | Targeted linear conjugates comprising polyethyleneimine and polyethylene glycol and polyplexes comprising the same |
| WO2025238236A1 (en) | 2024-05-16 | 2025-11-20 | Targimmune Therapeutics Ag | Polyplexes of nucleic acids and targeted conjugates comprising polyethyleneimine and polyethylene glycol |
| CN119280422B (zh) * | 2024-10-09 | 2025-09-26 | 浙江大学 | 一种生物相容的双靶向药物递送二聚体纳米颗粒的制备方法 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8834920B2 (en) * | 2006-12-21 | 2014-09-16 | Alza Corporation | Liposome composition for targeting egfr receptor |
| US8278415B2 (en) | 2006-12-21 | 2012-10-02 | Centocor, Inc. | Dimeric high affinity EGFR constructs and uses thereof |
| CN102007145A (zh) * | 2008-02-14 | 2011-04-06 | 百时美施贵宝公司 | 基于结合egfr的工程化蛋白质的靶向治疗剂 |
| ES2721850T3 (es) * | 2008-06-16 | 2019-08-05 | Pfizer | Nanopartículas poliméricas terapéuticas que comprenden alcaloides vinca y procedimientos de fabricación y uso de las mismas |
| JP2012501965A (ja) * | 2008-06-16 | 2012-01-26 | バインド バイオサイエンシズ インコーポレイテッド | 薬剤を装填したポリマーナノ粒子及びその製造方法と使用方法 |
| CN102099016A (zh) * | 2008-06-16 | 2011-06-15 | 佰恩德生物科学股份有限公司 | 载药的聚合物纳米微粒及其制备和使用方法 |
| US20120052041A1 (en) * | 2009-02-04 | 2012-03-01 | The Brigham And Women's Hospital, Inc. | Polymeric nanoparticles with enhanced drug-loading and methods of use thereof |
| EP2618846A1 (en) * | 2010-09-24 | 2013-07-31 | Mallinckrodt LLC | Aptamer conjugates for targeting of therapeutic and/or diagnostic nanocarriers |
| WO2012166923A2 (en) * | 2011-05-31 | 2012-12-06 | Bind Biosciences | Drug loaded polymeric nanoparticles and methods of making and using same |
| WO2014022535A1 (en) | 2012-07-31 | 2014-02-06 | The University Of Akron | Polymeric structures containing strained cycloalkyne functionality for post-fabrication azidealkyne cycloaddition functionalization |
| WO2014139182A1 (en) | 2013-03-15 | 2014-09-18 | Shenzhen Hightide Biopharmaceutical, Ltd. | Compositions and methods of using islet neogenesis peptides and analogs thereof |
| CN104045699A (zh) * | 2013-03-15 | 2014-09-17 | 深圳君圣泰生物技术有限公司 | 一种多肽、多肽衍生物、多肽的可药用盐及药物组合物 |
| WO2015157213A1 (en) * | 2014-04-08 | 2015-10-15 | California Institute Of Technology | Egfr-targeted nanoparticles |
| CN103893124B (zh) * | 2014-04-24 | 2016-08-24 | 中国药科大学 | 基于协同组装的基因治疗药物递送系统 |
-
2016
- 2016-08-19 CN CN201680081577.7A patent/CN108697815A/zh active Pending
- 2016-08-19 AU AU2016392719A patent/AU2016392719A1/en not_active Abandoned
- 2016-08-19 CA CA3013896A patent/CA3013896A1/en not_active Abandoned
- 2016-08-19 JP JP2018541254A patent/JP2019512006A/ja active Pending
- 2016-08-19 EP EP16890090.0A patent/EP3413917A4/en not_active Withdrawn
- 2016-08-19 WO PCT/US2016/047807 patent/WO2017138983A1/en not_active Ceased
- 2016-08-19 US US15/241,977 patent/US10137088B2/en not_active Expired - Fee Related
-
2018
- 2018-10-12 US US16/158,467 patent/US20190029960A1/en not_active Abandoned
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