JP2019512006A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2019512006A5 JP2019512006A5 JP2018541254A JP2018541254A JP2019512006A5 JP 2019512006 A5 JP2019512006 A5 JP 2019512006A5 JP 2018541254 A JP2018541254 A JP 2018541254A JP 2018541254 A JP2018541254 A JP 2018541254A JP 2019512006 A5 JP2019512006 A5 JP 2019512006A5
- Authority
- JP
- Japan
- Prior art keywords
- peg
- pla
- poly
- dbco
- conh2
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662293609P | 2016-02-10 | 2016-02-10 | |
| US62/293,609 | 2016-02-10 | ||
| US201662369590P | 2016-08-01 | 2016-08-01 | |
| US62/369,590 | 2016-08-01 | ||
| PCT/US2016/047807 WO2017138983A1 (en) | 2016-02-10 | 2016-08-19 | Therapeutic nanoparticles having egfr ligands and methods of making and using same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019512006A JP2019512006A (ja) | 2019-05-09 |
| JP2019512006A5 true JP2019512006A5 (https=) | 2019-09-19 |
Family
ID=59496509
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018541254A Pending JP2019512006A (ja) | 2016-02-10 | 2016-08-19 | Ｅｇｆｒリガンドを有する治療用ナノ粒子ならびにその作製および使用方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US10137088B2 (https=) |
| EP (1) | EP3413917A4 (https=) |
| JP (1) | JP2019512006A (https=) |
| CN (1) | CN108697815A (https=) |
| AU (1) | AU2016392719A1 (https=) |
| CA (1) | CA3013896A1 (https=) |
| WO (1) | WO2017138983A1 (https=) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX374963B (es) | 2011-04-29 | 2025-03-06 | Selecta Biosciences Inc | Nanoportadores sintéticos tolerogénicos para reducir las respuestas de anticuerpos. |
| BR122020023215B1 (pt) | 2013-05-03 | 2022-11-22 | Selecta Biosciences, Inc | Composição e kit de nanocarreadores sintéticos tolerogênicos para reduzir ou prevenir anafilaxia em resposta a um antígeno não alergênico |
| JP7242180B2 (ja) | 2014-09-07 | 2023-03-20 | セレクタ バイオサイエンシーズ インコーポレーテッド | 抗ウイルス導入ベクター免疫応答を減弱化するための方法および組成物 |
| CN110366428B (zh) | 2016-12-30 | 2024-05-17 | Vaxcyte公司 | 具有非天然氨基酸的多肽-抗原缀合物 |
| US11951165B2 (en) | 2016-12-30 | 2024-04-09 | Vaxcyte, Inc. | Conjugated vaccine carrier proteins |
| ES3036482T3 (en) | 2017-03-11 | 2025-09-19 | Cartesian Therapeutics Inc | Methods and compositions related to combined treatment with anti-inflammatories and synthetic nanocarriers comprising an immunosuppressant |
| CN109966780B (zh) * | 2019-03-21 | 2021-03-09 | 浙江工商大学 | 一种水生贝类蒸煮汤中功能性纳米颗粒的分离方法 |
| AU2020287627A1 (en) | 2019-06-04 | 2021-11-18 | Selecta Biosciences, Inc. | Formulations and doses of PEGylated uricase |
| MX2022011248A (es) * | 2020-03-11 | 2022-12-15 | Selecta Biosciences Inc | Metodos y composiciones relacionados con nanoportadores sinteticos. |
| WO2022040006A1 (en) * | 2020-08-19 | 2022-02-24 | The Trustees Of The University Of Pennsylvania | Targeting cartilage egfr pathway for osteoarthritis treatment |
| CN114133432B (zh) * | 2021-11-01 | 2023-06-16 | 暨南大学 | 一种抑制肿瘤细胞生长和转移的靶向肽及其应用 |
| WO2023079677A1 (ja) * | 2021-11-05 | 2023-05-11 | 日本電信電話株式会社 | 分子拡散評価方法およびシステム |
| WO2023079142A2 (en) | 2021-11-05 | 2023-05-11 | Targimmune Therapeutics Ag | Targeted linear conjugates comprising polyethyleneimine and polyethylene glycol and polyplexes comprising the same |
| CN114813998B (zh) * | 2022-03-24 | 2023-05-23 | 天津键凯科技有限公司 | 一种聚合物的检测方法 |
| CN115006390B (zh) * | 2022-06-27 | 2024-04-19 | 国药集团动物保健股份有限公司 | 一种病毒减毒制剂、其制备方法以及应用 |
| CN115317515B (zh) * | 2022-07-19 | 2024-08-20 | 沈阳药科大学 | 氯尼达明/牛血清白蛋白/磷酸铁多效协同仿生矿化纳米制剂及制备方法和应用 |
| US20260000700A1 (en) | 2022-11-07 | 2026-01-01 | Targimmune Therapeutics Ag | Targeted linear conjugates comprising polyethyleneimine and polyethylene glycol and polyplexes comprising the same |
| IL320618A (en) | 2022-11-07 | 2025-07-01 | Targimmune Therapeutics Ag | Polyplexes of nucleic acids and targeted pairs containing polyethyleneimine and polyethylene glycol |
| WO2025238236A1 (en) | 2024-05-16 | 2025-11-20 | Targimmune Therapeutics Ag | Polyplexes of nucleic acids and targeted conjugates comprising polyethyleneimine and polyethylene glycol |
| CN119280422B (zh) * | 2024-10-09 | 2025-09-26 | 浙江大学 | 一种生物相容的双靶向药物递送二聚体纳米颗粒的制备方法 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8834920B2 (en) * | 2006-12-21 | 2014-09-16 | Alza Corporation | Liposome composition for targeting egfr receptor |
| US8278415B2 (en) * | 2006-12-21 | 2012-10-02 | Centocor, Inc. | Dimeric high affinity EGFR constructs and uses thereof |
| AU2009213141A1 (en) | 2008-02-14 | 2009-08-20 | Bristol-Myers Squibb Company | Targeted therapeutics based on engineered proteins that bind EGFR |
| CN102099016A (zh) * | 2008-06-16 | 2011-06-15 | 佰恩德生物科学股份有限公司 | 载药的聚合物纳米微粒及其制备和使用方法 |
| US8318211B2 (en) * | 2008-06-16 | 2012-11-27 | Bind Biosciences, Inc. | Therapeutic polymeric nanoparticles comprising vinca alkaloids and methods of making and using same |
| EA020954B1 (ru) * | 2008-06-16 | 2015-03-31 | Бинд Терапьютикс, Инк. | Загруженные лекарственным средством полимерные наночастицы, фармацевтическая композиция и способ лечения рака |
| WO2010091187A2 (en) * | 2009-02-04 | 2010-08-12 | The Brigham And Women's Hospital, Inc. | Polymeric nanoparticles with enhanced drug-loading and methods of use thereof |
| EP2618846A1 (en) * | 2010-09-24 | 2013-07-31 | Mallinckrodt LLC | Aptamer conjugates for targeting of therapeutic and/or diagnostic nanocarriers |
| US20140308363A1 (en) * | 2011-05-31 | 2014-10-16 | Bind Therapeutics, Inc. | Drug loaded polymeric nanoparticles and methods of making and using same |
| CA2878059A1 (en) * | 2012-07-31 | 2014-02-06 | The University Of Akron | Polymeric structures containing strained cycloalkyne functionality for post-fabrication azidealkyne cycloaddition functionalization |
| US20160039877A1 (en) * | 2013-03-15 | 2016-02-11 | Shenzhen Hightide Biopharmaceutical, Ltd. | Compositions and methods of using islet neogenesis peptides and analogs thereof |
| CN104045699A (zh) * | 2013-03-15 | 2014-09-17 | 深圳君圣泰生物技术有限公司 | 一种多肽、多肽衍生物、多肽的可药用盐及药物组合物 |
| WO2015157213A1 (en) * | 2014-04-08 | 2015-10-15 | California Institute Of Technology | Egfr-targeted nanoparticles |
| CN103893124B (zh) * | 2014-04-24 | 2016-08-24 | 中国药科大学 | 基于协同组装的基因治疗药物递送系统 |
-
2016
- 2016-08-19 CN CN201680081577.7A patent/CN108697815A/zh active Pending
- 2016-08-19 JP JP2018541254A patent/JP2019512006A/ja active Pending
- 2016-08-19 US US15/241,977 patent/US10137088B2/en not_active Expired - Fee Related
- 2016-08-19 AU AU2016392719A patent/AU2016392719A1/en not_active Abandoned
- 2016-08-19 WO PCT/US2016/047807 patent/WO2017138983A1/en not_active Ceased
- 2016-08-19 EP EP16890090.0A patent/EP3413917A4/en not_active Withdrawn
- 2016-08-19 CA CA3013896A patent/CA3013896A1/en not_active Abandoned
-
2018
- 2018-10-12 US US16/158,467 patent/US20190029960A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2019512006A5 (https=) | ||
| Afsharzadeh et al. | Recent advances in co-delivery systems based on polymeric nanoparticle for cancer treatment | |
| JP2014531456A5 (https=) | ||
| Cheng et al. | Tandem synthesis of core− shell brush copolymers and their transformation to peripherally cross-linked and hollowed nanostructures | |
| Baranello et al. | Poly (styrene-alt-maleic anhydride)-based diblock copolymer micelles exhibit versatile hydrophobic drug loading, drug-dependent release, and internalization by multidrug resistant ovarian cancer cells | |
| Yang et al. | Synthesis and physicochemical characterization of amphiphilic triblock copolymer brush containing pH-sensitive linkage for oral drug delivery | |
| Callari et al. | Polymers with platinum drugs and other macromolecular metal complexes for cancer treatment | |
| Kumar et al. | N-desmethyl tamoxifen and quercetin-loaded multiwalled CNTs: A synergistic approach to overcome MDR in cancer cells | |
| Dhanikula et al. | Synthesis and evaluation of novel dendrimers with a hydrophilic interior as nanocarriers for drug delivery | |
| Zhang et al. | Poly (l-histidine) based triblock copolymers: pH induced reassembly of copolymer micelles and mechanism underlying endolysosomal escape for intracellular delivery | |
| Yu et al. | Functional polylactide-g-paclitaxel–poly (ethylene glycol) by azide–alkyne click chemistry | |
| Duong et al. | Acid degradable and biocompatible polymeric nanoparticles for the potential codelivery of therapeutic agents | |
| Hoang et al. | Triblock copolymers for nano-sized drug delivery systems | |
| Seidi et al. | Functional materials generated by allying cyclodextrin-based supramolecular chemistry with living polymerization | |
| JP2011507946A5 (https=) | ||
| JP2015528510A5 (https=) | ||
| Aghajanzadeh et al. | The role of miktoarm star copolymers in drug delivery systems | |
| Jiang et al. | A pH-sensitive nano drug delivery system of doxorubicin-conjugated amphiphilic polyrotaxane-based block copolymers | |
| Li et al. | Series of new β-cyclodextrin-cored starlike carriers for gene delivery | |
| Qiu et al. | Use of pH-active catechol-bearing polymeric nanogels with glutathione-responsive dissociation to codeliver bortezomib and doxorubicin for the synergistic therapy of cancer | |
| Nguyen et al. | Folate‐conjugated chitosan‐pluronic P123 nanogels: synthesis and characterizations towards dual drug delivery | |
| Chen et al. | Poly (2-(diethylamino) ethyl methacrylate)-based, pH-responsive, copolymeric mixed micelles for targeting anticancer drug control release | |
| Burts et al. | Brush‐first and Click: Efficient Synthesis of Nanoparticles that Degrade and Release Doxorubicin in Response to Light | |
| Chen et al. | Amphiphilic poly (ethylene glycol)-b-poly (ethylene brassylate) copolymers: One-pot synthesis, self-assembly, and controlled drug release | |
| Li et al. | Synthesis and characterization of dendritic star-shaped zwitterionic polymers as novel anticancer drug delivery carriers |