JP2019501687A5 - - Google Patents
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- Publication number
- JP2019501687A5 JP2019501687A5 JP2018525783A JP2018525783A JP2019501687A5 JP 2019501687 A5 JP2019501687 A5 JP 2019501687A5 JP 2018525783 A JP2018525783 A JP 2018525783A JP 2018525783 A JP2018525783 A JP 2018525783A JP 2019501687 A5 JP2019501687 A5 JP 2019501687A5
- Authority
- JP
- Japan
- Prior art keywords
- syringe
- prefilled syringe
- prefilled
- vegf
- silicone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 229940071643 prefilled syringe Drugs 0.000 claims 16
- 239000005557 antagonist Substances 0.000 claims 6
- 102000005789 Vascular Endothelial Growth Factors Human genes 0.000 claims 4
- 108010019530 Vascular Endothelial Growth Factors Proteins 0.000 claims 4
- 239000007788 liquid Substances 0.000 claims 4
- 238000002360 preparation method Methods 0.000 claims 4
- 206010012688 Diabetic retinal oedema Diseases 0.000 claims 3
- 206010047571 Visual impairment Diseases 0.000 claims 3
- 201000011190 diabetic macular edema Diseases 0.000 claims 3
- 239000012669 liquid formulation Substances 0.000 claims 3
- 208000029257 vision disease Diseases 0.000 claims 3
- 230000004393 visual impairment Effects 0.000 claims 3
- 208000005590 Choroidal Neovascularization Diseases 0.000 claims 2
- 206010060823 Choroidal neovascularisation Diseases 0.000 claims 2
- 229920000089 Cyclic olefin copolymer Polymers 0.000 claims 2
- 206010064930 age-related macular degeneration Diseases 0.000 claims 2
- 229920001577 copolymer Polymers 0.000 claims 2
- 208000030533 eye disease Diseases 0.000 claims 2
- 208000002780 macular degeneration Diseases 0.000 claims 2
- 239000002245 particle Substances 0.000 claims 2
- 208000004644 retinal vein occlusion Diseases 0.000 claims 2
- 206010012689 Diabetic retinopathy Diseases 0.000 claims 1
- 208000001344 Macular Edema Diseases 0.000 claims 1
- 206010025415 Macular oedema Diseases 0.000 claims 1
- 206010073286 Pathologic myopia Diseases 0.000 claims 1
- 108091008605 VEGF receptors Proteins 0.000 claims 1
- 102000009484 Vascular Endothelial Growth Factor Receptors Human genes 0.000 claims 1
- 229960002833 aflibercept Drugs 0.000 claims 1
- 108010081667 aflibercept Proteins 0.000 claims 1
- 239000000427 antigen Substances 0.000 claims 1
- 102000036639 antigens Human genes 0.000 claims 1
- 108091007433 antigens Proteins 0.000 claims 1
- 201000005667 central retinal vein occlusion Diseases 0.000 claims 1
- 239000011248 coating agent Substances 0.000 claims 1
- 238000000576 coating method Methods 0.000 claims 1
- 239000012634 fragment Substances 0.000 claims 1
- 108020001507 fusion proteins Proteins 0.000 claims 1
- 102000037865 fusion proteins Human genes 0.000 claims 1
- 201000010230 macular retinal edema Diseases 0.000 claims 1
- 229920001296 polysiloxane Polymers 0.000 claims 1
- 229960003876 ranibizumab Drugs 0.000 claims 1
- 230000002207 retinal effect Effects 0.000 claims 1
- 210000001957 retinal vein Anatomy 0.000 claims 1
- 239000004447 silicone coating Substances 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022144630A JP2022177129A (ja) | 2015-11-18 | 2022-09-12 | Ｖｅｇｆ拮抗薬を収容したプレフィルドプラスチックシリンジ |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15195177.9 | 2015-11-18 | ||
| EP15195177 | 2015-11-18 | ||
| PCT/EP2016/078136 WO2017085253A1 (en) | 2015-11-18 | 2016-11-18 | Pre-filled plastic syringe containing a vegf antagonist |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022144630A Division JP2022177129A (ja) | 2015-11-18 | 2022-09-12 | Ｖｅｇｆ拮抗薬を収容したプレフィルドプラスチックシリンジ |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019501687A JP2019501687A (ja) | 2019-01-24 |
| JP2019501687A5 true JP2019501687A5 (https=) | 2020-01-09 |
Family
ID=54608352
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018525783A Pending JP2019501687A (ja) | 2015-11-18 | 2016-11-18 | Ｖｅｇｆ拮抗薬を収容したプレフィルドプラスチックシリンジ |
| JP2022144630A Pending JP2022177129A (ja) | 2015-11-18 | 2022-09-12 | Ｖｅｇｆ拮抗薬を収容したプレフィルドプラスチックシリンジ |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022144630A Pending JP2022177129A (ja) | 2015-11-18 | 2022-09-12 | Ｖｅｇｆ拮抗薬を収容したプレフィルドプラスチックシリンジ |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US20180326126A1 (https=) |
| EP (1) | EP3377151A1 (https=) |
| JP (2) | JP2019501687A (https=) |
| KR (1) | KR20180083377A (https=) |
| CN (1) | CN108290004A (https=) |
| AU (1) | AU2016356047B2 (https=) |
| BR (1) | BR112018010005A2 (https=) |
| MX (1) | MX2018006171A (https=) |
| RU (1) | RU2018121813A (https=) |
| WO (1) | WO2017085253A1 (https=) |
| ZA (1) | ZA201802922B (https=) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9840553B2 (en) | 2014-06-28 | 2017-12-12 | Kodiak Sciences Inc. | Dual PDGF/VEGF antagonists |
| KR102799807B1 (ko) | 2015-12-30 | 2025-04-24 | 코디악 사이언시스 인코포레이티드 | 항체 및 이의 접합체 |
| AU2017213103B2 (en) | 2016-01-26 | 2022-08-11 | Formycon Ag | Liquid formulation of a VEGF antagonist |
| IL275102B2 (en) | 2017-12-13 | 2024-06-01 | Regeneron Pharma | Devices and methods for precision dose delivery |
| US20200390596A1 (en) | 2018-01-03 | 2020-12-17 | Irenix Medical, Inc. | Therapeutic Agent Delivery Devices Having Integrated Pain Mitigation, and Methods for Using the Same |
| FI3743091T3 (fi) | 2018-01-26 | 2025-01-03 | Univ California | Menetelmät ja koostumukset verisuoniperäisten sairauksien hoitoon käyttämällä anti-vegf vaikuttavia aineita |
| MX2020009152A (es) | 2018-03-02 | 2020-11-09 | Kodiak Sciences Inc | Anticuerpos de il-6 y constructos de fusion y conjugados de los mismos. |
| US11103552B2 (en) | 2018-05-10 | 2021-08-31 | Regeneron Pharmaceuticals, Inc. | High concentration VEGF receptor fusion protein containing formulations |
| EP3873519A1 (en) | 2018-10-29 | 2021-09-08 | F. Hoffmann-La Roche AG | Antibody formulation |
| ES2841807T3 (es) * | 2018-11-30 | 2021-07-09 | Klaus Stegemann | Jeringuilla de aplicación que contiene una solución estéril con un principio activo médico y procedimiento para su facilitación |
| CN118718181A (zh) | 2019-06-05 | 2024-10-01 | 里珍纳龙药品有限公司 | 用于精确剂量递送的装置及方法 |
| MX2022002355A (es) | 2019-09-03 | 2022-04-06 | Amgen Inc | Dispositivo de inyeccion para suministro de farmacos y envase para el dispositivo de inyeccion. |
| US12233177B2 (en) | 2019-09-16 | 2025-02-25 | Amgen Inc. | Method for external sterilization of drug delivery device |
| CA3157509A1 (en) | 2019-10-10 | 2021-04-15 | Kodiak Sciences Inc. | Methods of treating an eye disorder |
| WO2021108255A1 (en) | 2019-11-25 | 2021-06-03 | The Regents Of The University Of California | Long-acting vegf inhibitors for intraocular neovascularization |
| US11180540B2 (en) | 2019-12-06 | 2021-11-23 | Regeneron Pharmaceuticals, Inc. | Anti-VEGF protein compositions and methods for producing the same |
| JP2023525034A (ja) | 2020-05-08 | 2023-06-14 | リジェネロン・ファーマシューティカルズ・インコーポレイテッド | Ｖｅｇｆトラップおよびミニトラップならびに眼障害およびがんの治療方法 |
| CA3188860A1 (en) * | 2020-08-12 | 2022-02-17 | Bryan Grygus | Systems and methods for drug delivery to ocular tissue |
| US20230226280A1 (en) * | 2020-09-25 | 2023-07-20 | Ocuject, Llc | Syringe injector with a feedback mechanism |
| KR102720956B1 (ko) * | 2020-12-15 | 2024-10-24 | 삼천당제약주식회사 | 안과용 제형을 포함하는 시린지 |
| WO2022207655A1 (en) * | 2021-03-30 | 2022-10-06 | Schott Schweiz Ag | System for low-temperature storage of a pharmaceutical composition, liquid composition, method and uses |
| USD1120314S1 (en) | 2022-11-30 | 2026-03-24 | Regeneron Pharmaceuticals, Inc. | Dose delivery device |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3380450A (en) * | 1965-05-10 | 1968-04-30 | William H. Adelberger | Sterile disposable plastic prefilled syringe |
| US6124449A (en) | 1990-06-11 | 2000-09-26 | Nexstar Pharmaceuticals, Inc. | High affinity TGFβ nucleic acid ligands and inhibitors |
| US5731144A (en) | 1990-06-11 | 1998-03-24 | Nexstar Pharmaceuticals, Inc. | High affinity TGFβ nucleic acid ligands |
| US5731424A (en) | 1990-06-11 | 1998-03-24 | Nexstar Pharmaceuticals, Inc. | High affinity TGFβ nucleic acid ligands and inhibitors |
| US6582959B2 (en) | 1991-03-29 | 2003-06-24 | Genentech, Inc. | Antibodies to vascular endothelial cell growth factor |
| AU732820B2 (en) | 1995-06-02 | 2001-05-03 | Nexstar Pharmaceuticals, Inc. | High-affinity oligonucleotide ligands to growth factors |
| BR9207175A (pt) | 1992-10-28 | 1995-12-12 | Genentech Inc | Composição contendo antagonista de fator de crescimento de célula endotelial vascular sequência aminoácida de anticorpo monoclonal polipeptídeo e método de tratamento de tumor em mamífero |
| IL117645A (en) | 1995-03-30 | 2005-08-31 | Genentech Inc | Vascular endothelial cell growth factor antagonists for use as medicaments in the treatment of age-related macular degeneration |
| JP3957765B2 (ja) | 1997-04-07 | 2007-08-15 | ジェネンテク・インコーポレイテッド | 抗ｖｅｇｆ抗体 |
| US20020032315A1 (en) | 1997-08-06 | 2002-03-14 | Manuel Baca | Anti-vegf antibodies |
| EP2338915A3 (en) | 1997-04-07 | 2011-10-12 | Genentech, Inc. | Anti-VEGF antibodies |
| US6703020B1 (en) | 1999-04-28 | 2004-03-09 | Board Of Regents, The University Of Texas System | Antibody conjugate methods for selectively inhibiting VEGF |
| CN100523187C (zh) | 1999-06-08 | 2009-08-05 | 里珍纳龙药品有限公司 | 具有改善的药物动力学特性的修饰嵌合多肽 |
| US7431989B2 (en) | 2003-05-06 | 2008-10-07 | Tribofilm Research, Inc. | Article with lubricated surface and method |
| WO2005044853A2 (en) | 2003-11-01 | 2005-05-19 | Genentech, Inc. | Anti-vegf antibodies |
| EP2249801A2 (en) | 2008-02-07 | 2010-11-17 | Amgen Inc. | Stabilized protein compositions |
| LT3216803T (lt) | 2008-06-25 | 2020-06-10 | Novartis Ag | Stabilūs ir tirpūs antikūnai, slopinantys vegf |
| EP3785735A1 (en) | 2008-11-03 | 2021-03-03 | Molecular Partners AG | Binding proteins inhibiting the vegf-a receptor interaction |
| US9597458B2 (en) * | 2009-10-29 | 2017-03-21 | W. L. Gore & Associates, Inc. | Fluoropolymer barrier materials for containers |
| WO2011117878A1 (en) | 2010-03-20 | 2011-09-29 | Pawan Trilokchand Agrawal | Plastic pre-filled syringe |
| AU2011235002B2 (en) * | 2010-03-31 | 2016-08-11 | Ocuject, Llc | Device and method for intraocular drug delivery |
| TWI510246B (zh) | 2010-04-30 | 2015-12-01 | Molecular Partners Ag | 抑制ｖｅｇｆ－ａ受體交互作用的經修飾結合性蛋白質 |
| DE102011009057B4 (de) * | 2011-01-20 | 2015-12-10 | Schott Ag | Plasma-Behandlungsvorrichtung zur Herstellung von Beschichtungen und Verfahren zur innenseitigen Plasmabehandlung von Behältern |
| JP6207401B2 (ja) * | 2012-01-31 | 2017-10-04 | テルモ株式会社 | プレフィルドシリンジ用シリンジ |
| LT3679922T (lt) * | 2012-06-01 | 2021-10-25 | Novartis Ag | Švirkštas |
| AU2012101678B4 (en) | 2012-07-03 | 2013-01-24 | Novartis Ag | Use of device |
| DE202013000688U1 (de) * | 2012-07-03 | 2013-03-05 | Novartis Ag | Glas-Spritze |
| EP2890389A1 (en) * | 2012-08-28 | 2015-07-08 | Novartis AG | Use of a vegf antagonist in treating ocular vascular proliferative diseases |
| DE102013103676A1 (de) * | 2013-04-11 | 2014-10-30 | Schott Ag | Behälter mit geringer Partikelemission und reibkontrollierter Trockengleitoberfläche, sowie Verfahren zu dessen Herstellung |
| KR20160029794A (ko) * | 2013-07-11 | 2016-03-15 | 노파르티스 아게 | 소아 환자의 맥락망막 신생혈관성 및 투과성 장애의 치료에 있어서 vegf 길항제의 용도 |
| JP6898734B2 (ja) * | 2013-10-07 | 2021-07-07 | オクジェクト, リミテッド ライアビリティー カンパニーOcuject, Llc | 針アセンブリ |
| EP3202389A4 (en) * | 2014-10-02 | 2018-06-20 | Terumo Kabushiki Kaisha | Medical container for accommodating protein solution preparation therein |
-
2016
- 2016-11-18 CN CN201680067304.7A patent/CN108290004A/zh active Pending
- 2016-11-18 WO PCT/EP2016/078136 patent/WO2017085253A1/en not_active Ceased
- 2016-11-18 US US15/776,418 patent/US20180326126A1/en not_active Abandoned
- 2016-11-18 EP EP16801743.2A patent/EP3377151A1/en active Pending
- 2016-11-18 AU AU2016356047A patent/AU2016356047B2/en active Active
- 2016-11-18 KR KR1020187016631A patent/KR20180083377A/ko not_active Withdrawn
- 2016-11-18 MX MX2018006171A patent/MX2018006171A/es unknown
- 2016-11-18 JP JP2018525783A patent/JP2019501687A/ja active Pending
- 2016-11-18 RU RU2018121813A patent/RU2018121813A/ru unknown
- 2016-11-18 BR BR112018010005A patent/BR112018010005A2/pt not_active IP Right Cessation
-
2018
- 2018-05-04 ZA ZA2018/02922A patent/ZA201802922B/en unknown
-
2022
- 2022-07-18 US US17/867,098 patent/US20220362441A1/en not_active Abandoned
- 2022-09-12 JP JP2022144630A patent/JP2022177129A/ja active Pending
-
2025
- 2025-04-03 US US19/169,549 patent/US20250229010A1/en active Pending
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