JP2019500436A5 - - Google Patents
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- JP2019500436A5 JP2019500436A5 JP2018518979A JP2018518979A JP2019500436A5 JP 2019500436 A5 JP2019500436 A5 JP 2019500436A5 JP 2018518979 A JP2018518979 A JP 2018518979A JP 2018518979 A JP2018518979 A JP 2018518979A JP 2019500436 A5 JP2019500436 A5 JP 2019500436A5
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- JP
- Japan
- Prior art keywords
- monomer
- additive
- item
- polymer
- polymer composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 239000000178 monomer Substances 0.000 claims description 82
- 239000000203 mixture Substances 0.000 claims description 74
- 229920000642 polymer Polymers 0.000 claims description 69
- 239000000654 additive Substances 0.000 claims description 56
- 230000000996 additive effect Effects 0.000 claims description 52
- 230000003115 biocidal effect Effects 0.000 claims description 28
- 229920001296 polysiloxane Polymers 0.000 claims description 26
- 229920005601 base polymer Polymers 0.000 claims description 21
- NBVXSUQYWXRMNV-UHFFFAOYSA-N fluoromethane Chemical compound FC NBVXSUQYWXRMNV-UHFFFAOYSA-N 0.000 claims description 21
- -1 hydrogen compound Chemical class 0.000 claims description 17
- NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 claims description 15
- CERQOIWHTDAKMF-UHFFFAOYSA-M Methacrylate Chemical compound CC(=C)C([O-])=O CERQOIWHTDAKMF-UHFFFAOYSA-M 0.000 claims description 15
- 230000001737 promoting effect Effects 0.000 claims description 15
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 claims description 14
- 229920002554 vinyl polymer Polymers 0.000 claims description 14
- 238000000034 method Methods 0.000 claims description 12
- 229910052739 hydrogen Inorganic materials 0.000 claims description 10
- 239000001257 hydrogen Substances 0.000 claims description 10
- HRPVXLWXLXDGHG-UHFFFAOYSA-N Acrylamide Chemical compound NC(=O)C=C HRPVXLWXLXDGHG-UHFFFAOYSA-N 0.000 claims description 9
- 230000000844 anti-bacterial effect Effects 0.000 claims description 9
- VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 claims description 9
- 229920001228 polyisocyanate Polymers 0.000 claims description 8
- 239000005056 polyisocyanate Substances 0.000 claims description 8
- 125000003903 2-propenyl group Chemical group [H]C([*])([H])C([H])=C([H])[H] 0.000 claims description 6
- 125000000217 alkyl group Chemical group 0.000 claims description 6
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims description 6
- JFNLZVQOOSMTJK-KNVOCYPGSA-N norbornene Chemical compound C1[C@@H]2CC[C@H]1C=C2 JFNLZVQOOSMTJK-KNVOCYPGSA-N 0.000 claims description 6
- 229920000747 poly(lactic acid) Polymers 0.000 claims description 6
- 238000004519 manufacturing process Methods 0.000 claims description 5
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims description 4
- 238000000137 annealing Methods 0.000 claims description 4
- VAZJLPXFVQHDFB-UHFFFAOYSA-N 1-(diaminomethylidene)-2-hexylguanidine Polymers CCCCCCN=C(N)N=C(N)N VAZJLPXFVQHDFB-UHFFFAOYSA-N 0.000 claims description 3
- ZILVNHNSYBNLSZ-UHFFFAOYSA-N 2-(diaminomethylideneamino)guanidine Chemical group NC(N)=NNC(N)=N ZILVNHNSYBNLSZ-UHFFFAOYSA-N 0.000 claims description 3
- PKNYOSSVCITOFL-UHFFFAOYSA-N 2-[1-(4-chlorophenyl)-1-hydroxyethyl]guanidine Chemical compound ClC1=CC=C(C=C1)C(C)(O)NC(=N)N PKNYOSSVCITOFL-UHFFFAOYSA-N 0.000 claims description 3
- GRJRKPMIRMSBNK-UHFFFAOYSA-N 3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctan-1-ol Chemical compound OCCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F GRJRKPMIRMSBNK-UHFFFAOYSA-N 0.000 claims description 3
- CDXFIRXEAJABAZ-UHFFFAOYSA-N 3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl 2-methylprop-2-enoate Chemical group CC(=C)C(=O)OCCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F CDXFIRXEAJABAZ-UHFFFAOYSA-N 0.000 claims description 3
- QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 claims description 3
- 229920002413 Polyhexanide Polymers 0.000 claims description 3
- 239000004433 Thermoplastic polyurethane Substances 0.000 claims description 3
- 229920002118 antimicrobial polymer Polymers 0.000 claims description 3
- 125000003118 aryl group Chemical group 0.000 claims description 3
- ZRALSGWEFCBTJO-UHFFFAOYSA-N guanidine group Chemical group NC(=N)N ZRALSGWEFCBTJO-UHFFFAOYSA-N 0.000 claims description 3
- 125000005496 phosphonium group Chemical group 0.000 claims description 3
- RWSOTUBLDIXVET-UHFFFAOYSA-O sulfonium Chemical compound [SH3+] RWSOTUBLDIXVET-UHFFFAOYSA-O 0.000 claims description 3
- 229920002803 thermoplastic polyurethane Polymers 0.000 claims description 3
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 claims description 2
- VVQNEPGJFQJSBK-UHFFFAOYSA-N Methyl methacrylate Chemical compound COC(=O)C(C)=C VVQNEPGJFQJSBK-UHFFFAOYSA-N 0.000 claims description 2
- 239000004677 Nylon Substances 0.000 claims description 2
- 239000004696 Poly ether ether ketone Substances 0.000 claims description 2
- 239000004695 Polyether sulfone Substances 0.000 claims description 2
- 239000004698 Polyethylene Substances 0.000 claims description 2
- 229920000954 Polyglycolide Polymers 0.000 claims description 2
- 239000004743 Polypropylene Substances 0.000 claims description 2
- 230000015572 biosynthetic process Effects 0.000 claims description 2
- 238000005266 casting Methods 0.000 claims description 2
- 230000001112 coagulating effect Effects 0.000 claims description 2
- 229920001577 copolymer Polymers 0.000 claims description 2
- 238000001523 electrospinning Methods 0.000 claims description 2
- 150000002431 hydrogen Chemical class 0.000 claims description 2
- 238000002156 mixing Methods 0.000 claims description 2
- 229920001778 nylon Polymers 0.000 claims description 2
- 229920002492 poly(sulfone) Polymers 0.000 claims description 2
- 229920000058 polyacrylate Polymers 0.000 claims description 2
- 229920001610 polycaprolactone Polymers 0.000 claims description 2
- 229920000515 polycarbonate Polymers 0.000 claims description 2
- 239000004417 polycarbonate Substances 0.000 claims description 2
- 229920000728 polyester Polymers 0.000 claims description 2
- 229920006393 polyether sulfone Polymers 0.000 claims description 2
- 229920002530 polyetherether ketone Polymers 0.000 claims description 2
- 229920000573 polyethylene Polymers 0.000 claims description 2
- 239000004633 polyglycolic acid Substances 0.000 claims description 2
- 239000004626 polylactic acid Substances 0.000 claims description 2
- 229920000193 polymethacrylate Polymers 0.000 claims description 2
- 229920001155 polypropylene Polymers 0.000 claims description 2
- 108010033949 polytyrosine Proteins 0.000 claims description 2
- 229920000915 polyvinyl chloride Polymers 0.000 claims description 2
- 239000004800 polyvinyl chloride Substances 0.000 claims description 2
- 238000010526 radical polymerization reaction Methods 0.000 claims description 2
- 239000002904 solvent Substances 0.000 claims description 2
- 239000011877 solvent mixture Substances 0.000 claims description 2
- 238000003786 synthesis reaction Methods 0.000 claims description 2
- DISIMYWRLZOXJK-UHFFFAOYSA-N 2-(1-hydroxyethyl)guanidine Chemical compound CC(O)N=C(N)N DISIMYWRLZOXJK-UHFFFAOYSA-N 0.000 claims 1
- 238000010348 incorporation Methods 0.000 claims 1
- 239000007943 implant Substances 0.000 description 7
- 125000005442 diisocyanate group Chemical group 0.000 description 4
- 230000000845 anti-microbial effect Effects 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 210000005036 nerve Anatomy 0.000 description 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- 150000003926 acrylamides Chemical class 0.000 description 2
- 150000001252 acrylic acid derivatives Chemical class 0.000 description 2
- 150000001412 amines Chemical class 0.000 description 2
- 238000000502 dialysis Methods 0.000 description 2
- 150000004985 diamines Chemical class 0.000 description 2
- 150000002009 diols Chemical class 0.000 description 2
- 150000004662 dithiols Chemical class 0.000 description 2
- 150000002734 metacrylic acid derivatives Chemical class 0.000 description 2
- 230000000399 orthopedic effect Effects 0.000 description 2
- 150000003573 thiols Chemical class 0.000 description 2
- PSBDWGZCVUAZQS-UHFFFAOYSA-N (dimethylsulfonio)acetate Chemical compound C[S+](C)CC([O-])=O PSBDWGZCVUAZQS-UHFFFAOYSA-N 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 238000002399 angioplasty Methods 0.000 description 1
- 230000002965 anti-thrombogenic effect Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 210000000481 breast Anatomy 0.000 description 1
- 239000000919 ceramic Substances 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 239000002131 composite material Substances 0.000 description 1
- 239000004053 dental implant Substances 0.000 description 1
- 238000003618 dip coating Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 230000009477 glass transition Effects 0.000 description 1
- 210000003709 heart valve Anatomy 0.000 description 1
- 238000002844 melting Methods 0.000 description 1
- 230000008018 melting Effects 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 239000000825 pharmaceutical preparation Substances 0.000 description 1
- 229940127557 pharmaceutical product Drugs 0.000 description 1
- YHHSONZFOIEMCP-UHFFFAOYSA-O phosphocholine Chemical compound C[N+](C)(C)CCOP(O)(O)=O YHHSONZFOIEMCP-UHFFFAOYSA-O 0.000 description 1
- 229950004354 phosphorylcholine Drugs 0.000 description 1
- 229920001515 polyalkylene glycol Polymers 0.000 description 1
- 229920002959 polymer blend Polymers 0.000 description 1
- 238000007639 printing Methods 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 230000002787 reinforcement Effects 0.000 description 1
- 238000004528 spin coating Methods 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 229940117986 sulfobetaine Drugs 0.000 description 1
- 230000002792 vascular Effects 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562240090P | 2015-10-12 | 2015-10-12 | |
| US62/240,090 | 2015-10-12 | ||
| PCT/US2016/056531 WO2017066242A1 (en) | 2015-10-12 | 2016-10-12 | Biocidally active polymer compositions |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019500436A JP2019500436A (ja) | 2019-01-10 |
| JP2019500436A5 true JP2019500436A5 (https=) | 2019-11-07 |
| JP7118000B2 JP7118000B2 (ja) | 2022-08-15 |
Family
ID=57281277
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018518979A Active JP7118000B2 (ja) | 2015-10-12 | 2016-10-12 | 殺生物活性ポリマー組成物 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US10827757B2 (https=) |
| EP (1) | EP3361868B1 (https=) |
| JP (1) | JP7118000B2 (https=) |
| CN (1) | CN108366561B (https=) |
| CA (1) | CA3001913C (https=) |
| ES (1) | ES2902972T3 (https=) |
| TW (1) | TWI756188B (https=) |
| WO (1) | WO2017066242A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MA52209A (fr) * | 2018-04-13 | 2021-02-17 | Bayer Ag | Formulation de mélanges insecticides avec du carbonate de propylène |
| EP3846867B1 (en) | 2018-09-06 | 2025-02-19 | Biomodics APS | A medical tubular device |
| US12559867B2 (en) | 2019-04-30 | 2026-02-24 | Cornell University | Fibers of polymers that have a backbone including a positively charged component of a zwitterionic moiety, and their use in implantable therapeutic delivery systems |
| US11007216B2 (en) | 2019-08-05 | 2021-05-18 | International Business Machines Corporation | Combination therapy to achieve enhanced antimicrobial activity |
| US11028264B2 (en) | 2019-08-05 | 2021-06-08 | International Business Machines Corporation | Polylysine polymers with antimicrobial and/or anticancer activity |
| KR102238313B1 (ko) * | 2019-09-19 | 2021-04-08 | 연세대학교 산학협력단 | 치과용 조성물 및 이를 포함하는 구강 내 장치 제조 방법 |
| KR20220104718A (ko) * | 2019-11-19 | 2022-07-26 | 루브리졸 어드밴스드 머티어리얼스, 인코포레이티드 | 비스비구아니드로 염화되는 폴리우레탄 조성물 |
| TWI876376B (zh) * | 2022-08-26 | 2025-03-11 | 可成科技股份有限公司 | 抗菌電化學織物及其製造方法 |
| TWI842550B (zh) * | 2023-06-02 | 2024-05-11 | 臺灣塑膠工業股份有限公司 | 抗菌矽膠材料、其製造方法及含其之植入式醫療器材 |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1215861A (en) | 1967-02-09 | 1970-12-16 | Minnesota Mining & Mfg | Cleanable stain-resistant fabrics or fibers and polymers therefor |
| US3995085A (en) | 1974-07-11 | 1976-11-30 | Minnesota Mining And Manufacturing Company | Fabrics treated with hybrid tetracopolymers and process |
| US4131731A (en) | 1976-11-08 | 1978-12-26 | Beatrice Foods Company | Process for preparing polycarbonates |
| US4921691A (en) | 1985-08-22 | 1990-05-01 | Stockel Richard F | Spray on wound dressing compositions |
| JP2819417B2 (ja) | 1989-04-17 | 1998-10-30 | 東レ・ダウコーニング・シリコーン株式会社 | 抗菌性シリコーンゴム粒状物の製造方法 |
| US6090901A (en) | 1991-07-05 | 2000-07-18 | Biocompatibles Limited | Polymeric surface coatings |
| FR2686610B1 (fr) * | 1992-01-27 | 1995-06-16 | Grp Int Pub Therapeutique | Polysiloxanes fonctionnels pour la realisation de resines a proprietes biocides permanentes et procede de fabrication de ces composes. |
| CA2103440A1 (en) * | 1993-06-11 | 1994-12-12 | Kimberly-Clark Worldwide, Inc. | Antimicrobial siloxane quaternary ammonium salts |
| GB9521253D0 (en) | 1995-10-17 | 1995-12-20 | Luthra Ajay K | Biocompatible lubricious hydrophilic materials for medical devices |
| JPH11279408A (ja) | 1997-06-02 | 1999-10-12 | Dainippon Ink & Chem Inc | 水性樹脂の製造法、水性硬化性樹脂組成物および水性塗料 |
| JPH11279527A (ja) | 1997-06-30 | 1999-10-12 | Asahi Glass Co Ltd | 防汚加工剤組成物、その製造方法およびそれを用いた被処理物 |
| US6146688A (en) | 1997-12-23 | 2000-11-14 | Morgan; Harry C. | Method of creating a biostatic agent using interpenetrating network polymers |
| GB2349644A (en) | 1999-05-01 | 2000-11-08 | Biointeractions Ltd | Infection resistant polymers, methods for their preparation, and their uses |
| JP2001294810A (ja) | 2000-04-12 | 2001-10-23 | Shin Etsu Chem Co Ltd | 水中防汚塗料組成物 |
| CA2349989A1 (en) | 2001-06-07 | 2002-12-07 | Paul J. Santerre | Bioactive surface modifiers for polymers and articles made therefrom |
| UA92479C2 (ru) * | 2005-01-27 | 2010-11-10 | Налко Компани | Композиция для личной гигиены, которая содержит гидрофобно модифицированные полимеры |
| MX2007011771A (es) | 2005-03-22 | 2008-03-14 | Biosafe Inc | Metodo para crear un agente antimicrobiano polimerico de amonio cuaternario que contiene silicio libre de solventes, el cual tiene propiedades antimicrobianas superiores sostenidas. |
| EP1976694A4 (en) | 2006-01-17 | 2010-06-30 | Interface Biologics Inc | ALCOHOL AND WATER RESISTANT NONWOVENS |
| EP2160193A4 (en) | 2007-05-14 | 2010-12-01 | Tyco Healthcare | COPOLYMERS OF FURANONE |
| US9533006B2 (en) | 2007-11-19 | 2017-01-03 | University Of Washington | Marine coatings |
| US9039748B2 (en) | 2008-04-07 | 2015-05-26 | Abbott Cardiovascular Systems Inc. | Method of securing a medical device onto a balloon and system thereof |
| EP2309851A2 (en) * | 2008-05-29 | 2011-04-20 | DSM IP Assets B.V. | Antimicrobial polymers and their uses |
| CA2735442C (en) | 2008-08-28 | 2018-09-11 | Evonik Canada Inc. | Thermally stable biuret and isocyanurate based surface modifying macromolecules and uses thereof |
| JP5519684B2 (ja) | 2008-10-28 | 2014-06-11 | アーケマ・インコーポレイテッド | 水分流動性ポリマー膜 |
| JP2012530052A (ja) | 2009-06-15 | 2012-11-29 | ディーエスエム アイピー アセッツ ビー．ブイ． | ホスロリルコリンをベースにする医療用両親媒性シリコーン |
| US20110200655A1 (en) | 2010-02-16 | 2011-08-18 | Michael Darryl Black | Systems and methods that kill infectious agents (bacteria) without the use of a systemic anti-biotic |
| US20110233810A1 (en) * | 2010-03-25 | 2011-09-29 | W. M. Barr & Company | Antimicrobial plastic compositions and methods for preparing same |
| US20130183262A1 (en) | 2011-10-27 | 2013-07-18 | Kenneth J. Wynne | Antimicrobial polymeric compositions |
| JP2014009306A (ja) * | 2012-06-29 | 2014-01-20 | Neos Co Ltd | 抗菌性組成物 |
| JP2014231056A (ja) * | 2013-04-30 | 2014-12-11 | 国立大学法人京都大学 | 親水性星型ポリマーを含有するポリフルオロ化合物の捕捉材及び当該捕捉材を用いた捕捉方法 |
| WO2015042020A1 (en) * | 2013-09-18 | 2015-03-26 | Lubrizol Advanced Materials, Inc. | Stable cross-linked polymers |
| ES2832456T3 (es) * | 2015-04-24 | 2021-06-10 | Lubrizol Advanced Mat Inc | Composiciones poliméricas de superficie modificada |
-
2016
- 2016-10-12 WO PCT/US2016/056531 patent/WO2017066242A1/en not_active Ceased
- 2016-10-12 CN CN201680072533.8A patent/CN108366561B/zh active Active
- 2016-10-12 US US15/767,771 patent/US10827757B2/en active Active
- 2016-10-12 ES ES16794455T patent/ES2902972T3/es active Active
- 2016-10-12 TW TW105132882A patent/TWI756188B/zh active
- 2016-10-12 JP JP2018518979A patent/JP7118000B2/ja active Active
- 2016-10-12 EP EP16794455.2A patent/EP3361868B1/en active Active
- 2016-10-12 CA CA3001913A patent/CA3001913C/en active Active
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