JP2019162329A - Medicine administration device - Google Patents

Abstract

To provide a medicine administration device which is easy for a user to use and can administrate a large amount of medicine in a relatively short time.SOLUTION: A medicine administration device 10 is provided with a plurality of needle members 16 arranged at a predetermined distance from each other, on the skin-facing surface 12a of an elongated base member 12 installed along the longitudinal direction of an elongated part of a user. The device subcutaneously administers a medicine supplied from a medicine container via a plurality of needle members 16, thereby reducing a burden on the skin and administering a large amount of medicine in a comparatively short time.SELECTED DRAWING: Figure 2

Description

  The present invention relates to a drug administration device for administering a liquid or gel-like drug subcutaneously in a living body.

  Biopharmaceuticals including antibody drugs contain high molecular weight components such as cells, antibodies, nucleic acids, proteins, and the like, and they are decomposed in the digestive tract when administered by taking tablets and the like, so that subcutaneous administration is required. Also, some small molecule drugs require subcutaneous administration. In order for a user who performs home treatment to use such a pharmaceutical that requires subcutaneous administration, means for allowing the user himself to perform subcutaneous administration is required.

  As an apparatus for performing subcutaneous administration of such a drug, a vaccine drug administration device as in Patent Document 1 has been proposed. In this medicine administration device, a syringe filled with a medicine is mounted on an administration section having a needle tube that punctures the user's skin, and the user himself pushes the syringe to inject the medicine. It has become.

  Patent Document 2 proposes a drug administration device that continuously administers a drug using a pump unit.

JP-A-2006-104312 JP-A-2006-198412

  In recent years, in the treatment using biopharmaceuticals, in order to obtain a certain effect, the dose of a single drug tends to increase. Therefore, there is a need for a drug administration device that can subcutaneously administer a high volume of antibody drug at a time.

  However, in the drug administration device of Patent Document 1, if an attempt is made to increase the volume of a drug administered subcutaneously at once, troubles such as swelling occur in the user's skin, and a high volume drug is administered subcutaneously. Is difficult.

  Further, in the drug administration device of Patent Document 2, a high-capacity drug can be administered by continuously and slowly administering using a pump unit or by administering multiple times. However, long-time administration and frequent administration tend to increase pain, which may cause the user to feel resistance to administration.

  Accordingly, an object of the present invention is to provide a drug administration device that can be easily used by a user and can administer a large volume of drug in a relatively short time.

  In order to achieve the above object, a drug administration device according to the present invention is provided in a long base member installed along a longitudinal direction of a long part of a user, the base member, and the base member A plurality of needle members that are spaced apart from each other by a predetermined distance along the longitudinal direction, a housing portion that houses a medicine container filled with a medicine inside, and formed in the base member, the housing portion, A drug flow path communicating with the plurality of needle members, and an extruding means for pushing out the drug filled in the drug container are provided.

  According to the above-described drug administration device, a drug can be administered subcutaneously through a plurality of needle members that are spaced apart from each other by a predetermined distance. The amount of drug that can be administered at one time with a single needle member is limited to about 2 mL. However, by separating a plurality of needle members from each other by a predetermined distance, a high-capacity drug exceeding the limit can be shortened. Can be administered subcutaneously over time.

  In the above-mentioned drug administration device, the needle member can be pierced into the skin while extending from the protrusion, a flat flange, a protrusion having a contact surface protruding from the flange and the tip contacting the skin You may have a needle tube which has a needle tip, and an annular wall part which projected and formed from the flange part so that the circumference of the projection part may be surrounded. According to this drug administration device, the needle tube can be punctured substantially perpendicularly to the skin by tensioning the skin with the annular wall portion, and the protrusion can restrict the intrusion of the needle tube, thereby reducing the needle tube to a certain depth. Can puncture. Therefore, even a user who is unfamiliar with the operation of the syringe can puncture the needle tube to an appropriate depth and easily administer the drug subcutaneously.

  In the above-described drug administration device, a plurality of needle members may be arranged in a row in the longitudinal direction of the base member. As a result, the needle members are arranged in a line along the longitudinal direction of the arm, and the angle of each needle member with respect to the skin surface is constant, so that each needle member can be punctured under substantially the same conditions, and a high-volume drug can be administered subcutaneously Becomes easier. In this case, even if the said several flange part is formed on the same plane along the longitudinal direction of the said base member, the angle with respect to the skin surface of each needle member can be made constant. In the drug administration device, the needle tube may have a protruding length that reaches the skin of the user. Thereby, subcutaneous administration can be performed easily.

  In the medicine administration device, the base member is provided with a foot portion extending in a direction orthogonal to the longitudinal direction of the base member, and the foot portion is inclined toward the needle member side with respect to the main surface of the base member. May be. As a result, the foot contacts the surface of the arm so as to capture the curvature of the arm, and the drug administration device can be stably fixed to the arm without wobbling.

  In the above-described drug administration device, the container includes a container provided on the side of the base member opposite to the needle member placement surface, and a drug container detachably attached to the container. May be. Thus, the drug administration device can be used a plurality of times by exchanging the drug container.

  In the medicine administration device, the push-out means includes a pusher that pushes out the medicine in the housing portion, and the medicine in the housing portion is pushed out as the pusher moves in the longitudinal direction of the base member. You may do it. By comprising in this way, an extrusion means can be arrange | positioned without being bulky substantially parallel to the longitudinal direction of a user's elongate site | part. Accordingly, it is possible to act while wearing the drug administration device, and it is possible to eliminate the disadvantage that the user's behavior is restricted during subcutaneous administration.

  In the above-described drug administration device, the push-out means may be a screw mechanism. Thereby, the user can perform an operation of pushing out the medicine from the medicine container only by turning the screw mechanism. By adopting such a simple device structure, the user can easily use it, and the user's resistance to administration by subcutaneous administration can be reduced.

  The drug administration device may include a ratchet mechanism that prevents backflow caused by movement of the push-out means in the reverse direction. Thereby, the backflow of the bodily fluid from a biological body to the chemical | medical agent container side can be prevented in the case of subcutaneous administration.

  In the above-described drug administration device, the drug flow path has a through-hole penetrating the base member in the longitudinal direction, a branch portion branched from the through-hole toward the needle tube, and communicated with the needle tube of the needle member, and the through-hole And a closing member that closes the end of each. As a result, the shape of the drug channel can be configured only in a straight portion that does not bend inside the base member, and a channel that is difficult to block against a highly viscous drug can be formed. Can be formed.

  According to another aspect of the present invention, a subcutaneous administration device includes a long base member installed along a longitudinal direction of a long part of a user, and a base member provided on the base member, and mutually extending along the longitudinal direction of the base member. Formed on the base member, a plurality of needle members that are spaced apart from each other by a predetermined distance, a housing part that detachably accommodates the medicine container, a push-out means that pushes out the medicine in the medicine container housed in the housing part, and And a drug flow path for guiding the drug in the drug container to the plurality of needle members.

  The drug administration device according to the present invention can be easily used by a user and can administer a large volume of drug in a relatively short time.

It is a figure showing an example of wearing of a medicine administration device concerning a 1st embodiment of the present invention. 1 is a perspective view of a drug administration device according to a first embodiment of the present invention. FIG. 3 is a bottom view of the drug administration device of FIG. 2. FIG. 3 is an exploded perspective view of the drug administration device of FIG. 2. It is sectional drawing of the chemical | medical agent administration device of FIG. It is a perspective view of the medicine administration device concerning a 2nd embodiment of the present invention. It is sectional drawing of the chemical | medical agent administration device of FIG. It is a perspective view of the medicine administration device concerning a 3rd embodiment of the present invention. It is sectional drawing of the chemical | medical agent administration device of FIG.

  Hereinafter, preferred embodiments of the present invention will be described in detail with reference to the accompanying drawings.

(First embodiment)
As shown in FIG. 2, the drug administration device 10 according to the present embodiment includes an elongated base member 12 that is formed in an elongated shape, and the base member 12 is provided with a plurality of needle members 16. Further, on the side opposite to the surface 12a (hereinafter referred to as “skin-opposing surface”) on which the needle member 16 of the base member 12 is provided, the accommodating portion 28 that accommodates a drug container 56 (see FIG. 4) filled with the drug. (See FIG. 4). The accommodating portion 28 is covered with the cover body 14.

  As shown in FIG. 1, such a drug administration device 10 has a longitudinal direction of the base member 12 (Y direction in the figure) aligned with the longitudinal direction of the user's arm, and a plurality of needle members 16 are placed on the user's skin. Are used at the same time. Then, by simultaneously administering the drug subcutaneously from the plurality of needle members 16, it is possible to administer a high volume of drug. Details of the drug administration device 10 will be described below.

  The base member 12 has a skin facing surface 12a that faces the user's skin when the drug administration device 10 is used, and a plurality of needle members 16 are arranged on the skin facing surface 12a. Each needle member 16 includes a flange portion 26 formed in a flat disk shape, a protruding portion 22 protruding from the center of the flange portion 26, a needle tube 20 protruding from the protruding portion 22, and the protruding portion 22 and the needle tube 20. An annular wall portion 24 protruding from the flange portion 26 so as to surround the periphery is provided. The needle tubes 20 provided on each needle member 16 are parallel to each other.

  As shown in FIG. 5, the needle tube 20 is composed of a hard hollow tube having a needle hole 21 in the axial center portion. A needle tip 20 a having a sharp blade surface is formed at the tip of the needle tube 20. The thickness of the needle tube 20 is not particularly limited, but is 26 to 33 gauge size (0.2 mm to 0.45 mm). Examples of the material constituting the needle tube 20 include stainless steel, aluminum alloy, titanium, titanium alloy, other metals, and hard resin. The needle tube 20 is fixed to the protrusion 22.

  The protruding portion 22 is formed in a substantially cylindrical shape, and an attachment hole 22b for accommodating and fixing the needle tube 20 is formed in the axial center portion. The needle tube 20 is fixed to the needle member 16 and the base member 12 with an adhesive or the like while being accommodated in the mounting hole 22b. The tip of the protruding portion 22 slightly protrudes in the tip direction from the annular wall portion 24, and comes into contact with the surface of the user's skin at the tip surface 22a. The needle tube 20 protrudes from the distal end surface 22a by a length (protrusion length) that can be punctured under the user's skin. The distal end surface 22a defines the depth of puncture of the needle tube 20 by contacting the surface of the skin when the needle tube 20 is punctured subcutaneously. That is, the depth at which the needle tube 20 is punctured is determined by the protruding length of the needle tube 20 with respect to the distal end surface 22a. Here, the protruding length of the needle tube 20 can be, for example, about 1 mm to 8 mm.

  The size of the distal end surface 22a is determined in consideration of the distal end surface 22a pressing the skin around the needle tube 20 and applying an appropriate pressure to the bulge formed in the subcutaneous tissue by the injection of the drug. That is, the size of the distal end surface 22a is set so that the distal end surface 22a can press the skin around the needle tube 20 to prevent the administered medicine from leaking. The diameter of the front end surface 22a can be set to about 4 mm, for example.

  The annular wall portion 24 is a wall-shaped portion formed in a cylindrical shape so as to go around a portion away from the protruding portion 22 by a predetermined distance, and protrudes short from the flange portion 26 toward the distal end side. When the drug administration device 10 is used, the entire end surface 24a of the annular wall 24 contacts the user's skin. Thereby, the skin around the needle tube 20 is tensioned and plays a role of adjusting the direction of the skin so that the needle tube 20 is substantially perpendicular to the skin. Thereby, the blurring of the angle of the needle tube 20 can be prevented, and the puncture length of the needle tube 20 with respect to the skin can be made constant.

  As shown in FIG. 2, the diameter D of the annular wall 24 is preferably set to a value equal to or greater than the diameter of the bulge formed in the skin by the injection of the drug. Specifically, the diameter D is determined to be in a range of 8 mm or more. More preferably, the diameter D is set in a range of 11 mm or more. Thereby, it can prevent that injection | pouring of a chemical | medical agent is inhibited by a pressure being applied to the swelling of skin by the annular wall part 24. FIG.

  In addition, when the diameter D of the annular wall portion 24 increases, the number of needle members 16 that can be installed on the base member 12 decreases, and a desired amount of medicine cannot be administered subcutaneously at a time. Therefore, it is preferable to make the diameter D of the annular wall portion 24 as small as possible within a range where the injection of the medicine is not hindered.

  The flange portion 26 is a portion that flatly extends in a disc shape outward from the protrusion 22 in the radial direction. The vicinity of the outer periphery of the distal end surface 26 a of the flange portion 26 is a portion that comes into contact with the skin when the drug administration device 10 is used. By pushing the drug administration device 10 until the distal end surface 26a comes into contact, it can be shown to the user that the annular wall 24 is pressing the skin with an appropriate pressure. In addition, it replaces with the flange part 26, the base member 12 is formed in the width | variety equivalent to the flange part 26, and it is comprised so that a suitable pressure may be notified to a user when the side surface of the base member 12 contacted skin. May be.

  The height from the distal end surface 26a of the flange portion 26 to the distal end surface 24a of the annular wall portion 24 is set so that the needle tube 20 and the annular wall portion 24 can puncture the skin with an appropriate pressing force. The specific height of the annular wall portion 24 can be appropriately set according to the diameter D of the annular wall portion 24.

  The projecting portion 22, the annular wall portion 24, and the flange portion 26 may be formed integrally with the base member 12, and the material thereof may be a resin material such as polycarbonate, polypropylene, or polyethylene. it can.

  As shown in FIG. 3, the needle tubes 20 of adjacent needle members 16 are spaced apart from each other by a distance L. This distance L is set to such a distance that bulges generated subcutaneously by the drug administered subcutaneously to the adjacent needle tube 20 do not overlap. This distance L is set to at least 1 mm or more, more preferably 5 mm or more. This makes it possible to administer a high volume of drug subcutaneously while preventing troubles such as swelling of the skin.

  In the illustrated example, the distances L are the same. In the illustrated example, three needle members 16 are provided, but the drug administration device 10 is not limited to this, and 2 to 100 needle members 16 may be provided. More preferably, 2 to 10 can be provided. When three or more needle members 16 are provided, the interval between the needle tubes 20 is sufficient if the minimum distance L can be secured, and the distance L between the needle tubes 20 may not be constant.

  The plurality of needle members 16 are preferably arranged in a line along a straight line extending in the longitudinal direction of the base member 12. In this case, the plurality of needle tips 20a are arranged on the same straight line. Thereby, the needle members 16 are arranged in a line along the longitudinal direction of the arm, and the angle of each needle member 16 with respect to the skin surface is constant. As a result, each needle member 16 can be punctured under substantially the same conditions, and the drug can be administered subcutaneously. In this case, the flange portion 26 of each needle member 16 may be formed on the same plane.

  As shown in FIG. 2, a pair of feet 18 extends from the side of the base member 12 toward the outside in the width direction of the base member 12. When the base member 12 is attached to the user's arm, the foot portion 18 is inclined and extended toward the distal end side with respect to the skin facing surface 12a of the base member 12 so as to come into contact with the curvature of the arm. . When the longitudinal direction of the base member 12 is fitted with the longitudinal direction of the user's arm by such a foot portion 18, the foot portion 18 captures the curvature of the user's arm and contacts the skin surface. The base member 12 can be fixed to the arm without wobbling.

  Further, the foot 18 is provided with an opening 18a. As shown in FIG. 1, a belt-like fixing member 11 such as an adhesive tape, a Velcro tape, or a belt can be attached to the opening 18a. If the fixing member 11 is wound around the user's arm, it is preferable that the drug administration device 10 can be fixed more firmly with a constant pressing force without wobbling the user's arm.

  As shown in FIG. 4, a container 28 and a medicine container 56 are provided on the surface of the base member 12 opposite to the skin facing surface 12 a. The medicine container 56 filled with the medicine is accommodated in the accommodating portion 28. The accommodating portion 28 accommodates the long drug container 56 while being laid along the longitudinal direction (Y direction) of the base member 12. The housing portion 28 is provided with a frame portion 30, a first wall portion 34, and a second wall portion 36.

  The frame portion 30 is formed to rise from the vicinity of the center of the base member 12 toward the opposite side of the skin facing surface 12a, and a circular opening 30a is formed. The inner diameter of the opening 30 a is formed to be slightly larger than the diameter of the cylindrical barrel 48 of the drug container 56, and the barrel 48 of the drug container 56 is held in the opening 30 a and fixed to the base member 12.

  The first wall portion 34 is a wall-shaped member that is formed to rise from one end portion in the longitudinal direction (Y1 direction in the drawing) of the base member 12 toward the side opposite to the skin facing surface 12a. On the surface of the first wall portion 34 on the frame portion 30 side, a nozzle receiving portion 32 extends toward the frame portion 30. The nozzle receiving part 32 receives the nozzle 46 of the medicine container 56 held by the frame part 30 and connects the medicine container 56 to the base member 12.

  The second wall portion 36 is a wall-shaped member that is formed to rise from the other end (Y2 direction) in the longitudinal direction of the base member 12 toward the opposite side of the skin facing surface 12a. A screw hole 38 is formed. A screw member 40 is attached to the screw hole 38. The screw member 40 has a shaft portion 42 and a knob 44. A screw groove is formed in the shaft portion 42, and the screw groove of the shaft portion 42 engages with the screw hole 38. When the knob 44 of the screw member 40 is rotated in a predetermined direction, the shaft portion 42 moves forward in the Y1 direction, and the pusher 52 of the medicine container 56 accommodated in the accommodating portion 28 is driven. That is, the screw mechanism including the screw member 40 and the screw hole 38 constitutes an extruding unit that pushes out the pusher 52 of the medicine container 56.

  Note that the drive mechanism may be configured by attaching an elastic member such as a compression coil spring to the second wall portion 36 instead of the screw hole 38 and the screw member 40. Moreover, it is good also as a drive mechanism which replaces the screw hole 38 with a through-hole, attaches the rod-shaped member which penetrates the inside, and can push the pushing element 52 directly by a user's hand.

  As the medicine container 56 accommodated in the accommodating portion 28, a prefilled syringe prefilled with a medicinal solution can be used. The medicine container 56 is detachably attached to the accommodating portion 28. Thereby, the medicine administration device 10 can be used a plurality of times. In addition, not only the medicine container 56 but also an existing syringe or a prefilled syringe can be attached to the storage unit 28.

  A nozzle 46 to be inserted into the nozzle receiving portion 32 of the base member 12 is formed at the distal end portion of the illustrated medicine container 56. The nozzle 46 communicates with a medicine storage space 48 a inside the barrel 48, and when the nozzle 46 is pushed into the nozzle receiving portion 32, the nozzle 46 is in close contact with the nozzle receiving portion 32 and is liquid-tightly connected. A long barrel 48 is formed on the base end side of the nozzle 46.

  In the barrel 48, a gasket 50 inserted so as to be relatively movable in the barrel 48 is inserted in a liquid-tight manner, and a pusher 52 for pressing the gasket 50 is attached to the base end side of the gasket 50. It has been. A storage space 48 a inside the barrel 48 is sealed with a gasket 50. When the proximal end portion 54 of the pusher 52 is pressed toward the distal end side and the gasket 50 is moved toward the distal end side (Y1 direction), the medicine stored in the storage space 48a is pushed out toward the nozzle 46 side. As the medicine container 56, a removable cartridge type container may be used instead of the prefilled syringe. Instead of the removable medicine container 56, the medicine in the base member 12 may be directly filled.

  A cover body 14 that covers the accommodating portion 28 is attached to the base member 12. The cover body 14 has a thin plate-like upper end portion 14 c that comes into contact with the upper ends of the first and second wall portions 34 and 36 and the frame portion 30. A pair of side wall portions 14b covering the side portions of the accommodating portion 28 are formed to extend toward the skin facing surface 12a side from both side portions in the width direction (X direction) of the upper end portion 14c. Furthermore, an abutting surface 14a inclined according to the curvature of the arm is formed at the lower end of the side wall portion 14b. When the contact surface 14a contacts the skin of the user's arm, the drug administration device 10 can be attached to the user's arm in a stable state.

  In the drug administration device 10, by mounting such a cover body 14, when the user wears the drug administration device 10 and uses it, the drug container 56 can be protected and the drug container 56 can be prevented from falling off. . Thereby, the wearability is improved, and the user can perform various actions even when the drug administration device 10 is still worn. In addition, as a material which comprises the cover body 14, the resin member similar to the base member 12 can be used. Moreover, you may enable it to visually recognize the residual amount of the internal chemical | medical agent container 56 by comprising a part or whole of the cover body 14 with a transparent material.

  As shown in FIG. 5, a drug flow path 37 that connects the connection hole 32 a of the nozzle receiving portion 32 of the first wall portion 34 and the needle hole 21 of the needle tube 20 is formed inside the base member 12. ing. One end of the drug channel 37 communicates with the connection hole 32 a of the nozzle receiving portion 32, and extends from the one end toward the base member 12 through the inside of the first wall portion 34. The base member 12 extends linearly toward the second wall 36. The drug channel 37 communicates with the needle hole 21 of each needle tube 20 via a branching portion 37 a branched toward the needle hole 21 of the needle tube 20. Thereby, the medicine pushed out from the medicine container 56 is configured to be discharged from the needle tips 20 a of the plurality of needle tubes 20 through the branched medicine flow path 37.

  In the drug administration device 10 described above, a ratchet mechanism may be provided to prevent the drug flow path 37 from flowing backward. In this case, for example, a plurality of claw pieces that engage with the base end portion 54 of the pusher 52 of the medicine container 56 and prevent the pusher 52 from moving in the reverse direction are provided inside the cover body 14 to ratchet. A mechanism may be configured. In the drug administration device 10, the drug flow path may be formed outside the base member 12. In this case, for example, a tube-shaped or groove-shaped flow path that connects the connection hole portion 32a of the nozzle receiving portion 32 and the needle hole 21 of the needle tube 20 may be used.

  The drug administration device 10 according to the present embodiment is basically configured as described above, and the operation thereof will be described below.

  As shown in FIG. 4, the medicine container 56 is attached to the base member 12 prior to use. The user is provided with a plurality of drug containers 56 from, for example, a medical institution. The user attaches the drug container 56 to the base member 12 when using the drug administration device 10 in accordance with the drug administration rules. Thereby, the medicine storage space 48 a of the medicine container 56 and the needle hole 21 of the needle tube 20 communicate with each other via the connection hole portion 32 a and the medicine flow path 37.

  Next, the screw member 40 is advanced and brought into contact with the pusher 52 of the medicine container 56 in order to prevent backflow to the medicine container 56. Thereafter, the drug administration device 10 is assembled by covering the cover body 14.

  Next, as shown in FIG. 1, the longitudinal direction of the drug administration device 10 is aligned with the longitudinal direction of the user's arm, and the drug administration device 10 is pressed against the user's arm. Further, the fixing member 11 is wound around the foot 18 and the drug administration device 10 is pressed against the user's arm and fixed. Thus, the needle tip 20a of the needle tube 20 is punctured into the user's skin with the annular wall portion 24 of the needle member 16 spreading the skin, and the needle tip 20a reaches the user's skin. In addition, the mounting site | part of the medicine administration device 10 is not limited to a user's arm, You may attach to a user's elongate site | parts, such as a leg | foot.

  Thereafter, the user rotates the knob 44 of the screw member 40 to advance the screw member 40 in the direction of the first wall portion 34 (Y1 direction). Thereby, the medicine filled in the storage space 48a of the medicine container 56 is gradually pushed out. The medicine pushed out of the medicine container 56 is distributed to the plurality of needle tubes 20 through the medicine flow path 37 inside the base member 12. The dispensed medicine is injected into the user's skin through a plurality of needle tubes 20.

  According to the drug administration device 10 as described above, the burden on the user's skin can be reduced by administering the drug from the plurality of needle members 16 that are spaced apart from each other. This makes it possible to administer a high-volume drug subcutaneously in a short time without causing problems such as swelling in the user's skin. Thereby, the pain of the user accompanying administration of a medicine can be reduced.

  Further, according to the drug administration device 10 of the present embodiment, the drive mechanism that pushes out the drug from the drug container 56 is manually operated using the screw member 40, thereby simplifying the structure and reducing the cost. Can do. In addition, the user can perform subcutaneous administration with a simple operation by simply rotating the knob 44. Furthermore, since complicated mechanical parts such as a pump unit do not intervene, it is difficult to break down, and subcutaneous administration can be reliably performed.

  According to the drug administration device 10 of the present embodiment, a plurality of needle members 16 are arranged along the longitudinal direction of the base member 12. With this configuration, when the drug administration device 10 is used with the longitudinal direction aligned with the longitudinal direction of the arm, a plurality of needle members 16 are arranged in the longitudinal direction of the user's arm. . With such an arrangement, each needle member 16 can be at substantially the same angle as the skin of the user's arm, and the needle tip 20a of the needle tube 20 can be punctured into the skin at a uniform depth. Even a user who is unfamiliar with the handling of the injection needle can easily perform subcutaneous administration.

  The drug administration device 10 of the present embodiment can accommodate a long drug container 56 while being laid along the longitudinal direction of the base member 12, so that the drug container 56 can be placed on the user's arm in a non-bulk orientation. Can be installed. As a result, the wearability is improved, and even when the drug administration device 10 is mounted, the user's behavior can be allowed to some extent, so that the user's burden on medication can be reduced.

(Second Embodiment)
As shown in FIG. 6, the drug administration device 80 according to the present embodiment includes a base member 60, a plurality of needle members 70, a nozzle receiving portion 62, and a closing member 64. The base member 60 is formed in an elongated shape, and is used by attaching the longitudinal direction thereof to the longitudinal direction of the user's arm. The lower side of the base member 60 is a flat skin facing surface 60a. A plurality of needle members 70 are arranged on the skin facing surface 60 a with a predetermined distance in the longitudinal direction of the base member 60. In the illustrated example, three needle members 70 are provided. However, the present invention is not limited to this, and more needle members 70 may be provided.

  The needle member 70 includes a columnar base shaft portion 66, a protruding portion 68 protruding from the tip end surface 66 a of the base shaft portion 66, and a needle tube 69 protruding from the tip end of the protruding portion 68. The base shaft portion 66 supports the protruding portion 68 and the needle tube 69, and protrudes from the skin facing surface 60a to the needle tube 69 side.

  The protruding portion 68 is a portion protruding in a cylindrical shape from the distal end surface 66a of the base shaft portion 66, and contacts the skin at the distal end surface 68a. The distal end surface 68a defines the depth at which the needle tube 69 is punctured in contact with the surface of the skin when the skin is punctured with the needle tube 69. The puncture depth of the needle tube 69 is determined by the length of the needle tube 69 protruding from the distal end surface 68a. The protruding length of the needle tube 69 may be a length that reaches the user's skin, and may be, for example, about 1 mm to 8 mm. The diameter of the protruding portion 68 is appropriately set in consideration of the pressure applied by the protruding portion 68 to the bulge formed on the skin by the injection of the drug into the skin.

  The base shaft portion 66 and the projecting portion 68 may be formed integrally with the base member 60, or may be configured by joining those formed as separate members to the base member 60. As shown in FIG. 7, the base shaft portion 66 and the projecting portion 68 are formed with attachment holes 67 a extending linearly toward the base shaft direction of the needle tube 69. The attachment hole 67 a communicates with a branch portion 67 b formed inside the base member 60. The branch portion 67 b extends to the vicinity of the center of the base member 60 and communicates with a through hole 61 that penetrates the base member 60 in the longitudinal direction.

  The needle tube 69 has a needle hole 69a inside, a sharp needle tip 69b is formed at the tip, and can puncture the skin of the user. The needle tube 69 is inserted into an attachment hole 67a formed in the protruding portion 68 and the base shaft portion 66 and a branch portion 67b formed inside the base member 60, and is fixed by an adhesive or the like. A needle hole 69 a of the needle tube 69 communicates with the through hole 61.

  As shown in FIG. 7, a linear through hole 61 is provided inside the base member 60. The through hole 61 is formed so as to penetrate from one end surface 60b in the longitudinal direction of the base member 60 to the other end surface 60c. A nozzle receiving portion 62 into which the nozzle 46 of the medicine container 56 described with reference to FIG. 4 is inserted is formed on one end surface 60 b in the longitudinal direction of the base member 60. One end of the through hole 61 communicates with the connection hole 62 a of the nozzle receiving portion 62. A closing member 64 is provided at the other end of the through hole 61. The closing member 64 has the same structure as the nozzle receiving portion 62, but the connection hole portion 64 a is filled with the filler 72 and closes the end of the through hole 61. By providing the closing member 64, the other end of the through hole 61 is sealed, and the medicine is distributed and guided to the plurality of needle tubes 69.

  The drug administration device 80 of the present embodiment is used with the nozzle 46 of the drug container 56 as shown in FIG. The medicine container 56 is attached to the base member 60 in a state where its longitudinal direction is laid in a direction parallel to the longitudinal direction of the base member 60. Next, the needle tube 69 of the needle member 70 is punctured into the user's skin by attaching the base member 60 to the arm so that the longitudinal direction of the base member 60 matches the longitudinal direction of the user's arm. Thereafter, when the user manually presses the pusher 52 of the medicine container 56, the medicine can be administered subcutaneously to the user.

  In the drug administration device 80 of the present embodiment as described above, the drug flow path is configured by the linear through hole 61 and the branching portion 67b. For this reason, the drug flow path can be produced only by a simple drilling process, can be manufactured more easily than the drug administration device 10 having a structure in which the drug flow path is bent inside the base member 12, and is excellent in mass productivity.

  In the drug administration device 80 of the present embodiment, the foot 18 and the cover body 14 of the drug administration device 10 of FIG. 2 may be provided so that the drug can be stably fixed on the arm. Moreover, you may comprise so that the accommodating part may be provided in the end of the base member 60, and the chemical | medical agent container 56 may be accommodated in it.

(Third embodiment)
The basic configuration of the drug administration device 80A according to the present embodiment is the same as that of the drug administration device 80 of FIG. 6 except that the needle member 16 is provided instead of the needle member 70 and a support member 76 is provided. Different from the drug administration device 80. In addition, the same code | symbol is attached | subjected about the structure similar to the medicine administration device 10 and the medicine administration device 80 which were already demonstrated, and the detailed description is abbreviate | omitted.

  The drug administration device 80 </ b> A of the present embodiment includes an elongated base member 74 that is formed in an elongated shape, and a skin facing surface 74 a is formed below the base member 74. A plurality of needle members 16 are provided on the skin facing surface 74 a so as to be spaced apart from each other in the longitudinal direction of the base member 74. The arrangement and shape of these needle members 16 are the same as those of the needle members 16 described with reference to FIG.

  A nozzle receiving portion 62 that receives the nozzle 46 (see FIG. 4) of the medicine container 56 is formed on one end surface 74 b in the longitudinal direction of the base member 74. As shown in FIG. 9, a linear through hole 75 constituting a part of the drug flow path is formed inside the base member 74. The through hole 75 communicates with the needle hole via a branching portion 75b branched toward the attachment hole 75a for fixing the needle tube 20. Further, the through hole 75 penetrates to the other end surface 74c in the longitudinal direction of the base member 74, and the through hole 75 is closed by the closing member 64 on the other end surface 74c. Thereby, the medicine from the medicine container 56 connected to the nozzle receiving portion 62 is distributed and supplied to the needle member 16.

  In the drug administration device 80 </ b> A of the present embodiment, a pair of support members 76 extending from both side portions of the nozzle receiving portion 62 are provided on the end surface 74 b of the base member 74. The support member 76 is formed with a gap slightly wider than the width of the medicine container 56 to be mounted. The drug container 56 is held by the support member 76.

  According to the drug administration device 80A of the present embodiment, since the drug flow channel inside the base member 74 can be configured as the linear through hole 75, the drug flow channel can be formed by simple drilling, and mass productivity is achieved. Excellent. Further, by providing the needle member 16, even a user who is unfamiliar with the operation of the syringe can always puncture the needle tip 20a at a certain angle with respect to the skin and can easily perform subcutaneous administration.

  Further, in the medicine administration device 80A, the support member 76 is provided on both sides of the nozzle receiving portion 62 so as to support the medicine container 56, so that the medicine container 56 can be prevented from falling off during subcutaneous administration. The user can safely administer subcutaneously.

  In the above description, the present invention has been described with reference to preferred embodiments. However, the present invention is not limited to the above-described embodiments, and various modifications can be made without departing from the spirit of the present invention. Yes.

DESCRIPTION OF SYMBOLS 10, 80, 80A ... Drug administration device 12, 60, 74 ... Base member 14 ... Cover body 16, 70 ... Needle member 18 ... Foot part 20, 69 ... Needle tube 20a, 69b ... Needle tip 30 ... Frame part 40 ... Screw member 56 ... Drug container

Claims (12)

A long base member installed along the longitudinal direction of the long part of the user;
A plurality of needle members provided on the base member and arranged apart from each other by a predetermined distance along the longitudinal direction of the base member;
An accommodating portion for accommodating a drug container filled with a drug inside;
A drug flow path formed on the base member and connecting the accommodating portion and the plurality of needle members;
An extruding means for extruding the medicine filled in the medicine container;
A drug administration device comprising:   The drug administration device according to claim 1, wherein the plurality of needle members are arranged in a line in a longitudinal direction of the base member.   3. The drug administration device according to claim 1, wherein the needle member extends from the protruding portion, a flat flange portion, a protruding portion that protrudes from the flange portion and has an abutting surface that abuts against the skin. And a needle tube having a needle tip that can be punctured into the skin, and an annular wall formed to protrude from the flange so as to surround the periphery of the protrusion.   4. The drug administration device according to claim 3, wherein the plurality of flange portions are formed on the same plane along a longitudinal direction of the base member.   4. The drug administration device according to claim 3, wherein the needle tube has a protruding length that reaches the skin of the user.   2. The drug administration device according to claim 1, wherein the base member is provided with a foot portion extending in a direction orthogonal to a longitudinal direction of the base member, and the foot portion is more than the main surface of the base member. A drug administration device which is inclined toward the member side.   2. The drug administration device according to claim 1, wherein the storage part includes a storage part provided on an opposite side of the surface of the needle member of the base member, and a drug container removably attached to the storage part. And a drug administration device comprising:   2. The drug administration device according to claim 1, wherein the push-out means includes a pusher that pushes out the medicine in the housing portion, and the housing portion is moved as the pusher moves in a longitudinal direction of the base member. A drug administration device, wherein the drug is extruded.   9. The drug administration device according to claim 8, wherein the push-out means includes a screw mechanism.   9. The drug administration device according to claim 8, further comprising a ratchet mechanism that prevents backflow caused by movement of the push-out means in the reverse direction.   2. The drug administration device according to claim 1, wherein the drug flow path has a through-hole penetrating the base member in a longitudinal direction, and a branch portion that branches from the through-hole toward the needle tube and communicates with the needle tube of the needle member. And a closing member that closes the end of the through hole. A long base member installed along the longitudinal direction of the long part of the user;
A plurality of needle members provided on the base member and arranged apart from each other by a predetermined distance along the longitudinal direction of the base member;
An accommodating portion for detachably accommodating the drug container;
An extruding means for extruding the medicine in the medicine container housed in the housing portion;
A drug flow path formed in the base member for guiding the drug in the drug container to the plurality of needle members;
A drug administration device comprising:

Images