JP2019154982A - Medicine administration device - Google Patents

Abstract

To provide a medicine administration device which is simple, easy to use, and able to prevent increase in pain and leakage of medicine when high viscosity medicine is infused.SOLUTION: A medicine administration device 10 includes: a body 12 having a medicine filling part 38 in which medicine is filled inside; an operation part 16 which is displaced by the operation of a user; and an extruder 30 which extrudes medicine inside the medicine filling part 38 into a needle tube 21 by traveling in the medicine filling part 38 based on the displacement of the operation part 16. Between the body 12 and the operation part 16, there is provided a restriction part (elastic member 35) which restricts displacement of the extruder 30 by the operation part 16, thereby restraining the travel speed of the extruder 30 and preventing increase in an internal pressure of the medicine filling part 38.SELECTED DRAWING: Figure 4

Description

  The present invention relates to a drug administration device for administering a liquid or gel-like drug subcutaneously in a living body.

  Biopharmaceuticals including antibody pharmaceuticals contain high molecular weight components such as cells, antibodies, nucleic acids, proteins, and the like, and they are decomposed in the digestive tract when administered by taking tablets, etc., and therefore, subcutaneous administration is required. Some small molecule drugs require subcutaneous administration. In order for a user who performs home treatment to use such a pharmaceutical that requires subcutaneous administration, means for allowing the user himself to perform subcutaneous administration is required.

  As a device for performing subcutaneous administration of such a drug, a drug injection device as in Patent Document 1 has been proposed. In this drug injection device, it is disclosed that a drug provided percutaneously is injected by puncturing the skin with a needle provided at an end of a container filled with the drug solution.

  In Patent Document 2, a syringe filled with a medicine is mounted on an administration portion having a needle tube that punctures the user's skin, and the user himself pushes the pusher of the syringe to administer the medicine. It is disclosed.

JP-A-2005-87521 JP-A-2006-104312

  In recent years, in the treatment using a biopharmaceutical, the dose of a single drug is increasing in order to obtain a certain effect. For this reason, there exists a tendency for the density | concentration of a chemical | medical agent to become high and the viscosity of a chemical | medical solution to become high.

  However, when a high-viscosity drug solution is administered subcutaneously, the resistance pressure increases at the start of injection through the needle tube, pain increases at the time of injection, and drug leakage tends to occur.

  In addition, when a patient administers subcutaneously, the drug administration device is required to be simple and easy to use, and the complicated structure may cause a patient to feel repelled.

  An object of the present invention is to provide a drug administration device that is simple and easy to use and can prevent an increase in pain and leakage of a drug solution during injection of a high-viscosity drug solution.

  In order to achieve the above object, a drug administration device according to the present invention has a main body having a drug filling portion filled with a drug inside, a hollow needle tube communicating with the drug filling portion, and can puncture the skin. A needle member having a needle tip formed thereon, an operation part that is displaced by a user's operation, and a medicine filled in the medicine filling part by moving in the medicine filling part based on the displacement of the operation part. A pusher that is pushed out to a needle tube; and a suppression unit that is provided between the main body and the operation unit and suppresses the displacement of the pusher by the operation unit to suppress the movement speed of the pusher. It is characterized by.

  According to the above-described drug administration device, the drug can be injected with the operation force of the user's hand, so that the user can easily use it. In addition, by providing a suppression unit that suppresses the movement speed by suppressing the displacement of the pusher by the operation unit between the main body and the operation unit, the user accidentally applies excessive operation force. Even if it is, the moving speed of the pusher can be suppressed. Thereby, an increase in the internal pressure of the medicine filling portion can be prevented, and pain can be suppressed by reducing the momentum of the medicine discharge from the needle tube, and leakage of the medicine from the injection site can be prevented.

  In the above-described drug administration device, the suppression unit may be configured by an elastic member disposed between the pusher and the operation unit. In this case, the elastic member can be a leaf spring or a coil spring. In this medicine administration device, since the elastic member is disposed as a suppressing portion between the pusher and the operation portion, the displacement of the operation portion is transmitted to the pusher via the elastic member. Therefore, even when excessive pressing by the user is applied to the operation unit, the displacement of the operation unit can be absorbed by elastic compression of the elastic member. Thereby, the moving speed of the pusher can be suppressed to prevent an increase in the pressure in the medicine filling portion, and pain can be suppressed and medicine leakage can be prevented.

  In the medicine administration device, the pusher includes a partition wall formed to have a diameter substantially equal to that of the medicine filling part, and a column part extending from the partition wall to the operation part side, and the elastic member includes the elastic member, It may be attached to the pillar. In the above-mentioned medicine administration device, the upper end of the column part may be separated from the operation part, and the upper end part of the suppression part may contact the operation part.

  In the above-described drug administration device, the suppression unit may be a damper mechanism installed in parallel with the pusher between the operation unit and the main body. Here, the damper mechanism is a mechanism that generates a greater resistance force as the displacement speed of the operation unit increases using the viscous resistance of the fluid. By disposing the damper mechanism in parallel with the pusher, the damper mechanism generates a large resistance force against excessive pressing of the operation unit, and suppresses the displacement speed of the operation unit. Thereby, the pushing speed of the pusher is suppressed, and an increase in pressure in the medicine filling portion can be suppressed.

  In the above-described drug administration device, the operation unit includes an upper wall part and an outer wall extending downward from a peripheral part of the upper wall part, and the operation is performed when the outer wall contacts a side wall of the main body. The displacement direction of the part may be guided. In this way, the displacement direction of the operation portion is guided by the outer wall and the side wall of the main body, so that the pressing operation of the pusher can be performed smoothly.

  In the medicine administration device, a ratchet mechanism may be provided at a contact portion between the outer wall of the operation unit and the side wall of the main body to prevent the operation unit from moving in a direction away from the main body. Thereby, the displacement to the reverse direction of a pusher can be prevented, and the backflow toward a chemical | medical agent administration device from a user's body can be prevented.

  In the above-described drug administration device, the drug filling unit includes a container for storing a drug, a connection unit that detachably fixes the container to the main body, and the needle tube when the container is fixed to the main body. And a connecting portion that communicates. Thereby, a chemical | medical agent administration device can be used in multiple times by replacing | exchanging a chemical | medical agent filling part.

  The drug administration device according to the present invention is simple and easy to use, and can prevent an increase in pain and leakage of a drug when a high viscosity drug is injected.

FIG. 1A is a graph showing the transition of the pushing amount of the pusher when the high-viscosity drug solution is administered subcutaneously with a syringe, and FIG. 1B is a graph showing the change in the internal pressure of the drug filling portion with respect to the pushing amount of FIG. 1A. is there. It is a perspective view shown in the state where a medicine administration device concerning a 1st embodiment of the present invention was equipped on an arm. FIG. 3 is a perspective view of the lower surface (skin facing surface) side of the drug administration device of FIG. 2. FIG. 3 is an exploded perspective view of the drug administration device of FIG. 2. It is sectional drawing of the part along the VV line of FIG. It is sectional drawing of the chemical | medical agent administration device which concerns on the 2nd Embodiment of this invention. It is sectional drawing of the chemical | medical agent administration device which concerns on the 3rd Embodiment of this invention. It is a disassembled perspective view of the chemical | medical agent administration device which concerns on the 4th Embodiment of this invention. It is sectional drawing of the chemical | medical agent administration device of FIG.

  Hereinafter, preferred embodiments of the present invention will be described in detail with reference to the accompanying drawings.

When a high-viscosity drug is administered subcutaneously with a syringe, the needle tube or drug channel is not filled with the high-viscosity chemical solution for a while after the pressing of the pusher, and the resistance of the pusher is reduced. It is getting smaller. Therefore, even if the user intends to push the pusher with a constant force, as shown in FIG. 1A, the pusher tends to be pushed quickly. That is, during the period from the start of administration to T ₁ , the user pushes the pusher with a sense of pushing speed when the resistance is low.

  If such a high push-in speed is maintained, the needle tube and the drug flow path will eventually be filled with a high-viscosity drug solution, and the flow rate will decrease, and as shown in FIG. 1B, the internal pressure of the drug filling portion will increase. Resulting in. As a result, the internal pressure causing pain is exceeded during the injection of the chemical solution, and a high discharge pressure chemical solution is injected subcutaneously from the needle tip. This causes the user to feel sharp pain early in the injection. If the user feels pain, then the pressure of the pusher is loosened, the pushing speed becomes slower, the internal pressure of the drug filling part decreases, and the pain is reduced, but there is a feeling of discomfort due to the initial pain at the injection site. become.

  In order to suppress the increase in the internal pressure of the medicine filling part as described above, it is necessary to suppress the pushing speed of the pusher. Therefore, in the following embodiments of the present invention, a drug administration device capable of suppressing the pushing speed of the pusher will be described.

(First embodiment)
As shown in FIG. 2, the drug administration device 10 according to the present embodiment has a structure in which a cup-shaped operation unit 16 is placed on a cylindrical main body 12. A pair of attachment rings 14 are provided so as to face each other with the main body 12 interposed therebetween. A removable band 18 such as a Velcro tape is passed through the attachment ring 14, and the band 18 is wound around the user's arm to fix the drug administration device 10 to the arm. The attachment position of the drug administration device 10 is not limited to the arm, and can be attached to any part of the body such as a foot or a chest.

  The inside of the main body 12 is filled with a medicine, and is provided on the skin facing surface of the main body 12 (surface facing the skin, hereinafter referred to as the lower surface 12a) by the user manually operating the operation unit 16. It is comprised so that a chemical | medical agent may be inject | poured from the formed needle tube 21 (refer FIG. 3). Hereinafter, each part of the medicine administration device 10 will be further described. In the following description, the direction from the operation unit 16 toward the main body 12 is referred to as “downward”, and the direction from the main body 12 toward the operation unit 16 is referred to as “upward”.

  As shown in FIG. 3, a needle member 20 is provided at the center of the lower surface 12 a of the drug administration device 10. The needle member 20 includes a needle tube 21, a projecting portion 22 that supports the needle tube 21, and an annular wall portion 24 formed around the needle tube 21 and the projecting portion 22.

  The needle tube 21 is formed as a hard hollow tube having a needle hole in the axial center. A needle tip 21 a having a sharp blade surface is formed at the tip of the needle tube 21. Although the thickness of the needle tube 21 is not specifically limited, For example, it is a size (0.2 mm-0.45 mm) of 26-33 gauge. Examples of the material constituting the needle tube 21 include stainless steel, aluminum, aluminum alloy, titanium, titanium alloy, other metals, and hard resin. The needle tube 21 is fixed to the protrusion 22.

  The protrusion 22 is formed in a substantially cylindrical shape. As shown in FIG. 5, an attachment hole 22b for accommodating and fixing the needle tube 21 is formed in the axial center portion. The needle tube 21 is fixed to the main body 12 with an adhesive or the like while being accommodated in the mounting hole 22b. The tip of the protruding portion 22 slightly protrudes in the tip direction from the annular wall portion 24, and the tip surface 22a contacts the surface of the user's skin.

  The needle tube 21 protrudes by a length (protrusion length) that allows puncture from the distal end surface 22a to the user's skin. The distal end surface 22a defines the depth of puncture of the needle tube 21 by contacting the surface of the skin when the needle tube 21 is punctured subcutaneously. That is, the depth at which the needle tube 21 is punctured is determined by the protruding length of the needle tube 21 with respect to the distal end surface 22a. Here, the protruding length of the needle tube 21 can be, for example, about 1 mm to 8 mm.

  The size of the distal end surface 22a is determined by considering that the distal end surface 22a presses the skin around the needle tube 21 and applies an appropriate pressure to the bulge formed in the subcutaneous tissue by the injection of the drug. That is, the size of the distal end surface 22a is determined so that the distal end surface 22a can press the skin around the needle tube 21 and prevent the administered drug solution from leaking. The diameter of the front end surface 22a can be set to about 4 mm, for example.

  As shown in FIG. 3, the annular wall portion 24 is a wall-shaped portion that is formed in a cylindrical shape so as to go around a portion that is a predetermined distance away from the protruding portion 22, and extends from the lower surface 12 a to the tip side (downward). Protrusively short. When the drug administration device 10 is used, the annular wall 24 is in contact with the user's skin over its entire distal end surface 24a. As a result, the skin around the needle tube 21 is tensioned and plays a role of adjusting the direction of the skin so that the needle tube 21 is substantially perpendicular to the skin. As a result, the angle fluctuation of the needle tube 21 can be prevented, and the puncture length of the needle tube 21 with respect to the skin can be made constant.

  The inner diameter of the annular wall 24 is preferably set to a value equal to or greater than the diameter of the bulge formed on the skin by the injection of the drug. For example, the inner diameter can be 8 mm or more. More preferably, the inner diameter can be 11 mm or more. Thereby, it can prevent that injection | pouring of a chemical | medical agent is inhibited by a pressure being applied to the swelling of skin by the annular wall part 24. FIG.

  The protrusion 22 and the annular wall 24 may be formed integrally with the main body 12. The number of needle members 20 provided on the lower surface 12a of the main body 12 is not limited to one, and two or more needle members 20 may be provided as necessary.

  As shown in FIG. 4, the upper portion of the main body 12 is opened, and a drug filling portion 38 for storing the drug is provided therein. The main body 12 has a circular bottom surface 39, and a side wall 37 extends upward from the peripheral edge of the bottom surface 39. In addition, a recess 40 is formed at the center of the bottom surface 39.

  As shown in FIG. 5, a circular hole 31 is formed in the central portion of the lower end of the recess 40 and is formed in the axially downward direction. A needle holding member 36 is inserted inside the recess 40 and the hole 31. The needle holding member 36 is in liquid tight contact with the main body 12 at the hole 31. In addition, a through hole 36 a penetrating in the axial direction is provided at the center of the lower end of the needle holding member 36. The through hole 36 a communicates with a through hole 22 b provided in the protruding portion 22, and the needle tube 21 is held by these through holes 22 b and 36 a. The needle hole of the needle tube 21 communicates with the inside of the medicine filling portion 38.

  As shown in FIG. 4, the pusher 30 includes a partition wall 32 having a diameter substantially equal to the inner diameter of the medicine filling portion 38. A sealing member 34 is provided on the upper surface in the vicinity of the peripheral edge of the partition wall 32 to liquid-tightly close the gap between the partition wall 32 and the inner wall of the drug filling unit 38. The sealing member 34 includes, for example, a packing 34 a made of a material such as rubber or various elastomers, and the outer diameter of the packing 34 a is slightly larger than the inner diameter of the medicine filling portion 38. . The sealing member 34 is formed integrally with the partition wall 32, and can move along with the partition wall 32 while sliding in the drug filling portion 38 in the axial direction of the main body 12.

  A columnar column 33 for attaching the elastic member 35 is formed on the upper surface of the partition wall 32. The diameter of the column portion 33 is formed to be approximately equal to the inner diameter of the coil spring constituting the elastic member 35. Moreover, it is preferable to form the column part 33 short enough not to directly contact the upper wall part 16a of the operation part 16.

  The elastic member 35 is composed of a coil spring, for example, and is attached to the column portion 33 of the pusher 30. The upper end portion of the elastic member 35 is in contact with the upper wall portion 16 a of the operation portion 16, and transmits the force for pushing the operation portion 16 to the column portion 33 and the partition wall 32 constituting the pusher 30. The elastic member 35 can absorb excessive pressing of the operation unit 16 by contracting in the axial direction according to the compressing force from the operation unit 16. That is, in the present embodiment, the elastic member 35 constitutes a suppressing portion. The elastic member 35 is not limited to a coil spring, and may be constituted by a member such as a leaf spring, an elastically deformable sponge or rubber, for example. When the elastic member 35 is made of sponge or the like, the column portion 33 may not be provided.

  The operation portion 16 has a circular upper wall portion 16a, and a cylindrical outer wall 16b extends downward from a peripheral edge portion of the upper wall portion 16a. The inner diameter of the outer wall 16 b is slightly larger than the outer diameter of the main body 12. The operation unit 16 is fitted so that the inner peripheral surface 16d of the outer wall 16b is in contact with the side wall 37 of the main body 12 and overlaps from the outside. Thereby, the opening of the main body 12 is covered by the operation unit 16. When the outer side wall 16b contacts the side wall 37 of the main body 12, the moving direction of the operation unit 16 is guided in the axial direction. As the operation portion 16 moves downward, the upper wall portion 16 a of the operation portion 16 is pushed, and the displacement is transmitted to the pusher 30 via the elastic member 35. As a result, the chemical solution in the drug filling unit 38 is discharged from the needle tip 21 a of the needle tube 21.

  Resin materials such as polycarbonate, polypropylene, and polyethylene can be used for the main parts of the main body 12 and the operation unit 16. Moreover, you may comprise so that the quantity of the chemical | medical solution remaining in the chemical | medical agent filling part 38 can be confirmed by comprising at least one part of the main body 12 and the operation part 16 with a transparent member.

  In the above description, the configuration in which the drug filling portion 38 inside the main body 12 is directly filled with the drug solution is illustrated, but the present embodiment is not limited to this, and the cartridge-type drug filling portion is detachable. You may comprise so that it may attach to.

  The drug administration device 10 according to the present embodiment is basically configured as described above, and the operation thereof will be described below.

  First, as shown in FIG. 2, the drug administration device 10 is overlaid on the user's wearing site (for example, an arm), and the needle member 20 (see FIG. 3) is pressed against the user's skin, thereby the needle tip 21 a of the needle tube 21. Is punctured under the skin of the user. Thereafter, the band 18 is wound and the drug administration device 10 is pressed and fixed with a predetermined pressing force.

  Thereafter, the upper wall 16 a of the operation unit 16 is pressed by hand to push the operation unit 16 in a direction approaching the main body 12. Thereby, the operating force (pressing force) given to the operation part 16 is transmitted to the pusher 30 via the elastic member 35, and the pusher 30 advances toward the needle tip 21a. As a result, the drug solution filled in the drug filling unit 38 is discharged from the needle tip 21 a through the needle tube 21. In this way, the chemical solution is injected.

  In the drug administration device 10 of the present embodiment, since the elastic member 35 is disposed as a suppressing unit between the pusher 30 and the operation unit 16, the displacement of the operation unit 16 is applied to the pusher 30 via the elastic member 35. Reportedly. Therefore, even when excessive pressing by the user is applied to the operation unit 16, excessive displacement of the operation unit 16 can be absorbed by elastic compression of the elastic member 35 constituting the suppressing unit. Thereby, the moving speed of the pusher 30 can be suppressed to prevent an increase in the pressure of the medicine filling portion 38, and an increase in pain and leakage of the liquid medicine can be prevented. Moreover, since the medicine administration device 10 can administer medicine simply by pressing the operation unit 16, the user can easily use it.

(Second Embodiment)
As shown in FIG. 6, the drug administration device 10 </ b> A according to the present embodiment includes a damper mechanism 50 in addition to the main body 12 </ b> A, the pusher 30, the operation unit 16, and the needle member 20. 2 to 5 are different from the drug administration device 10 shown in FIG. In addition, about the structure similar to the chemical | medical agent administration device 10, the same code | symbol is attached | subjected and the detailed description is abbreviate | omitted.

  The main body 12A and the operation unit 16 of the drug administration device 10A are formed in a cylindrical shape, and the appearance thereof is the same as that of the drug administration device 10. In the main body 12 </ b> A of the present embodiment, the inside thereof is partitioned into a damper housing portion 52 and a medicine filling portion 38 by a partition wall 51.

  The medicine filling portion 38 is formed near the center axis of the main body 12A, and is configured so that the medicine can be filled therein. The bottom surface 39 of the medicine filling portion 38 is formed in a circular shape, and a concave portion 40 is formed at the center thereof. A needle holding member 36 is provided in the recess 40, and the needle tube 21 is held by the needle holding member 36. The needle hole of the needle tube 21 communicates with the drug filling portion 38. Moreover, the upper end side of the medicine filling portion 38 is opened, and a partition wall 32, a sealing member 34, and a column portion 33 constituting the pusher 30 are provided in the opening portion.

  The partition wall 32 and the sealing member 34 move in the direction of the needle tip 21 a while sliding in the drug filling portion 38, thereby pushing out the drug solution inside the drug filling portion 38 to the needle tube 21. The column part 33 formed on the partition wall 32 and the sealing member 34 is in contact with the upper wall part 16a of the operation part 16, and is pressed by the operation part 16 and integrated with the operation part 16 when the chemical solution is injected. Operate. That is, the displacement of the operation unit 16 is directly transmitted to the pusher 30.

  In the above description, the medicine filling portion 38 that directly fills the main body 12A with the medicine has been described as an example, but the present embodiment is not limited to this, and may be a cartridge-type medicine filling portion.

  The damper accommodating portion 52 is formed near the outer periphery of the main body 12A, and the damper mechanism 50 is accommodated therein. A shaft 46 extends from the damper mechanism 50, and the upper end of the shaft 46 is in contact with the upper wall portion 16 a of the operation portion 16. That is, the damper mechanism 50 is arranged in parallel with the partition wall 32 and the column portion 33 that constitute the pusher 30. The damper mechanism 50 has a highly viscous working fluid such as oil sealed in a sealed case 42, and the inside thereof is separated by a piston 44 into a first region 42 a and a second region 42 b. The piston 44 is formed with a pore 45 communicating the first region 42a and the second region 42b. A shaft 46 is connected to the piston 44, and an end of the shaft 46 is in contact with the upper wall portion 16 a of the operation unit 16.

  The drug administration device 10A of the present embodiment is configured as described above, and the operation thereof will be described below.

  10 A of chemical | medical agent administration devices start injection | pouring of a chemical | medical agent by pressing the operation part 16, after fixing to attachment parts, such as an arm. When the operation unit 16 is pressed, the operation unit 16 is pushed toward the main body 12A. As the operation unit 16 is displaced, the working fluid in the first region 42a inside the damper mechanism 50 passes through the pore 45 and moves to the second region 42b. At this time, due to the flow resistance when the working fluid passes through the pore 45, the damper mechanism 50 generates a repulsive force in a direction that hinders the displacement of the operation portion 16, and the repulsive force is transmitted to the operation portion 16 via the shaft 46. . Thereby, the moving speed of the operation part 16 is suppressed.

  The repulsive force generated by the damper mechanism 50 increases as the displacement speed of the operation unit 16 increases. Therefore, when the user accidentally presses the operation unit 16 with an excessive force, the repulsive force of the damper mechanism 50 is increased accordingly. That is, the suppression unit is configured by the damper mechanism 50, and an excessive pressing force (operation force) of the operation unit 16 by the user is suppressed by the damper mechanism 50, and the pushing speed of the pusher 30 can be suppressed. As a result, it is possible to prevent an increase in the internal pressure of the medicine filling portion 38. In this way, according to the drug administration device 10A, it is possible to prevent an increase in pain and a leak of the drug solution when the drug solution is injected.

(Third embodiment)
As shown in FIG. 7, the drug administration device 10 </ b> B according to this embodiment has the drug administration described with reference to FIGS. 2 to 5 in that the pusher 30 is pressed by the operation unit 16 via the elastic member 35. Similar to the device 10. The same components as those of the drug administration device 10 are denoted by the same reference numerals, and detailed description thereof is omitted.

  The drug administration device 10B is provided with a ratchet mechanism 56 at a contact portion between the operation unit 16 and the main body 12B so that backflow can be prevented even when the operation unit 16 is stopped in the middle. It has become. The ratchet mechanism 56 includes a plurality of tooth portions 55 formed on the side wall of the main body 12 </ b> B and a claw portion 57 that is formed on the operation portion 16 side and engages with the tooth portions 55.

  The tooth portion 55 has an upper surface 55a that protrudes gently inclined with respect to the side wall of the main body 12B, and a lower surface 55b that stands substantially perpendicular to the side wall. Are arranged side by side in the moving direction. On the other hand, the claw portion 57 is formed in the operation portion 16 corresponding to the tooth portion 55, and a claw 57 a that engages with the lower surface 55 b of the tooth portion 55 is formed on the distal end side of the claw portion 57. Yes. By engaging the claw portion 57 and the tooth portion 55, it is possible to prevent the operation portion 16 from going backward in a direction away from the main body 12B. That is, the operation unit 16 is displaced only in the direction in which it is pushed into the main body 12B. For this reason, the pusher 30 also moves only downward, which is the direction in which the pusher 30 is pushed into the main body 12B, and can prevent backflow from the needle tip 64a to the medicine filling portion 38.

  A plurality of needle tubes 64 are provided on the lower surface 12a of the main body 12B of the drug administration device 10B. The needle tube 64 has a needle tip 64a that can puncture the skin, and a needle hole 64b is formed therein. The needle tube 64 is held by the needle holding unit 60. A plurality of needle tubes 64 are attached to one needle holding portion 60, and a plurality of drug flow paths 62 a communicating with the needle holes 64 b of the needle tube 64 are formed inside the needle holding portion 60. These drug flow paths 62a merge with a thicker drug flow path 62b. The drug flow path 62b penetrates the main body 12B and communicates with the drug filling portion 38 inside the main body 12B.

  A plurality of needle holding portions 60 are provided on the lower surface 12a of the main body 12B, and each needle holding portion 60 is provided with drug flow paths 62a and 62b, respectively. In this way, the drug administration device 10B can inject a drug solution using the plurality of needle tubes 64 by distributing the drug through the plurality of drug flow paths 62a and 62b. Thereby, even a highly viscous drug solution can be rapidly administered subcutaneously.

(Fourth embodiment)
In the present embodiment, an example will be described in which a cartridge containing a medicine is replaceably attached instead of directly containing the medicine in the main body 12. As shown in FIG. 8, the drug administration device 10 </ b> C of the present embodiment includes a circular accommodating portion 38 a that can accommodate the cartridge 70 inside the main body 12 </ b> C. The cartridge 70 includes a cylindrical container 72 having a diameter slightly smaller than the inner diameter of the accommodating portion 38a. An upper end of the container 72 is opened, and a disc-shaped plate 82 having a diameter substantially the same as the inner diameter of the container 72 is inserted through the opening. As shown in FIG. 9, a seal member 86 such as an O-ring is attached to the outer peripheral portion of the plate 82.

  The seal member 86 is in liquid-tight contact with the inner peripheral surface of the container 72, and a space surrounded by the plate 82 and the inner wall of the container 72 is filled with a chemical solution containing a predetermined concentration of drug. A column portion 84 is formed at the center of the upper surface of the plate 82. The upper end surface 84 a of the column part 84 is separated from the upper wall part 16 a of the operation part 16. The displacement of the operation unit 16 is transmitted to the plate 82 via the elastic member 35. The plate 82 is slid along the inner wall of the container 72 by being pressed from the operation unit 16, and pushes the chemical solution filled in the container 72 to the needle tube 21. That is, the plate 82 and the column portion 84 constitute the pusher 80 of the drug administration device 10C.

  From the central part of the bottom 74 of the container 72, a cylindrical connecting part 76 having a diameter substantially the same as the inner diameter of the recess 40 protrudes in the axial direction (downward) of the container 72. The connecting portion 76 is a member penetrating in a cylindrical shape, and the base end side thereof communicates with a medicine storage space inside the container 72. A thin sheet-like seal member 78 is attached to the opening on the distal end side of the connecting portion 76 to seal the chemical solution inside the container 72. A thread 77 is formed on the outer surface of the connection portion 76, and the connection portion 76 can be screwed into the recess 40 by engaging the thread 77 with the thread groove 40 a on the inner wall of the recess 40. When the connection portion 76 is completely tightened into the recess 40, the connection portion 76 and the recess 40 are in close contact with each other. At the same time, the proximal end portion 21c of the needle tube 21 projecting upward from the main body 12C breaks through the seal member 78, whereby the needle hole of the needle tube 21 and the storage space of the container 72 communicate with each other.

  In the drug administration device 10C as described above, since the cartridge 70 (drug filling unit) that can be attached to and detached from the main body 12C is used, the drug administration device 10C can be repeatedly used simply by replacing the cartridge 70.

  In the above description, the present invention has been described with reference to preferred embodiments. However, the present invention is not limited to the above-described embodiments, and various modifications can be made without departing from the spirit of the present invention. Yes.

10, 10A, 10B, 10C ... Drug administration device 12, 12A, 12B, 12C ... Main body 16 ... Operation unit 18 ... Band 20 ... Needle member 21, 64 ... Needle tube 21a, 64a ... Needle tip 30, 80 ... Pusher 32 ... Partition 35 ... Elastic member 38 ... Drug filling part 50 ... Damper mechanism 56 ... Ratchet mechanism

Claims (9)

A main body having a medicine filling portion filled with medicine inside;
A needle member having a hollow needle tube communicating with the drug filling portion and having a needle tip that can be punctured into the skin;
An operation unit that is displaced by a user's operation;
A pusher that pushes the medicine filled in the medicine filling part to the needle tube by moving in the medicine filling part based on the displacement of the operation part;
A suppressing unit that is provided between the main body and the operation unit, and suppresses the movement speed of the pusher by suppressing displacement of the pusher by the operation unit;
A drug administration device comprising:   2. The drug administration device according to claim 1, wherein the suppressing portion is formed of an elastic member disposed between the pusher and the operation portion.   3. The drug administration device according to claim 2, wherein the elastic member is a leaf spring or a coil spring. The drug administration device according to claim 2 or 3, wherein the pusher includes a partition wall having a diameter substantially equal to that of the drug filling portion, and a column portion extending from the partition wall to the operation portion side. ,
The drug administration device, wherein the elastic member is attached to the column portion.   5. The drug administration device according to claim 4, wherein an upper end of the column part is separated from the operation part, and an upper end part of the suppression part is in contact with the operation part. device.   2. The drug administration device according to claim 1, wherein the suppression unit includes a damper mechanism disposed in parallel with the pusher between the operation unit and the main body. 3.   The drug administration device according to any one of claims 1 to 6, wherein the operation portion includes an upper wall portion and an outer wall extending downward from a peripheral edge portion of the upper wall portion. A drug administration device characterized in that a displacement direction of the operation portion is guided by a wall coming into contact with a side wall of the main body.   8. The drug administration device according to claim 7, wherein a ratchet mechanism is provided at a contact portion between the outer wall of the operation portion and the side wall of the main body to prevent the operation portion from being displaced in a direction away from the main body. A drug administration device.   9. The drug administration device according to claim 1, wherein the drug filling unit includes a container that stores a drug, a connection unit that detachably fixes the container to the main body, and the container. And a connecting portion that communicates with the needle tube when fixed to the main body.

Images