JP2019116460A - Tablet-shaped artificial tooth cleaning agent - Google Patents

Abstract

To provide a tablet-shaped artificial tooth cleaning agent in which a range of a compression condition in which, no compression failure occurs, is wide.SOLUTION: There is provided a tablet-shaped artificial tooth cleaning agent in which, alkyl glycoside is blended with a foam agent (carbonate compound and acid) in which, a range of a compression condition (pressure condition) in which no compression failure occurs, is wide.SELECTED DRAWING: None

Description

  The present invention relates to a tablet-like denture cleaner having a wide range of tableting conditions in which tableting problems do not occur.

  Dentures are susceptible to adhesion of bacteria, biofilms and other deposits regardless of whether they are complete dentures or partial dentures, and if left uncleaned, they cause bad breath and also cause periodontal disease. It may contribute to the induction of intraoral diseases such as Therefore, it is essential to clean and keep the denture as part of oral care. Cleaning with denture cleanser is important because bacteria and dirt adhering to the denture can not be removed sufficiently by brush cleaning.

  In general, cleaning of a denture with a denture cleaner is performed by a method of immersing and holding a denture in denture cleaning water prepared by introducing the denture cleaner into water. Conventionally, a denture detergent contains a surfactant and a foaming agent, and when it is added to water, it exerts a chemical detergency by its surface activation action and a physical detergency by its foam action to enhance the cleansing effect. It is designed as.

  Also, denture cleansers have conventionally been formulated and provided in various forms such as tablets, granules, powders and the like, and among these forms of formulations, tablets are easy to handle and allow consumers It is widely accepted. So far, various tablet preparation techniques have been reported for formulation techniques for improving detergency and disintegrability (for example, see Patent Documents 1 and 2).

JP 2001-505195 gazette Japanese Patent Application Laid-Open No. 2005-112640

  Tablet-like denture cleaners are characterized by inferior tableting moldability because they are compounded with a foaming agent (carbonic acid compound and acid), and capping (event in which the top and bottom of the tablet peel off), lamination (middle part of tablet) Is prone to tableting failure such as sticking in layers, sticking (in which part of the raw material adheres to a die or die and part of the tablet peels off). Therefore, in the production of a tablet-like denture cleaner, tableting conditions such as preload and pressure are set according to the composition so as not to cause tableting problems. However, if the range of tableting conditions where no tableting failure occurs is narrow, strict control of tableting conditions is required during industrial manufacture, and even if the tableting conditions are controlled more strictly, the temperature fluctuation Tableting failure may inevitably occur due to the influence of the condition of the raw material. Therefore, development of a tablet-like denture cleaner having a wide range of tableting conditions in which tableting problems do not occur is desired.

  Therefore, an object of the present invention is to provide a tablet-like denture cleaner having a wide range of tableting conditions in which tableting problems do not occur.

  The inventors of the present invention have conducted intensive studies to solve the above problems, and it has been found that tablet denture cleaners containing an alkyl glycoside together with a foaming agent (carbonic acid compound and acid) have tableting conditions that do not cause tableting problems ( It was found that the range of pressure conditions was broadened. The present invention has been completed by repeating studies based on such findings.

That is, the present invention provides the invention of the aspects listed below.
Item 1. A tablet comprising (A) at least one carbonic acid compound selected from the group consisting of (A) carbonates, hydrogencarbonates, and double salts of hydrogencarbonates and carbonates, (B) acid, and (C) alkyl glycosides. Denture Cleaner.
Item 2. Item 5. The tablet-like denture cleaner according to Item 1, wherein the alkyl glycoside is an alkyl glucoside having a hydrocarbon moiety of 8 to 22 carbon atoms.
Item 3. Item 3. The tablet denture cleaner according to item 1 or 2, wherein 0.1 to 3% by weight of the alkyl glycoside is contained.
Item 4. The tablet-like denture cleaner according to any one of Items 1 to 3, further comprising (D) a polyalkylene glycol.
Item 5. Item 5. The tablet-like denture cleaner according to Item 4, wherein the polyalkylene glycol is polyethylene glycol.
Item 6. Item 6. The tablet denture cleaner according to item 4 or 5, wherein 0.1 to 3% by weight of the polyalkylene glycol is contained.
Item 7. The tablet-like denture cleaner according to any one of Items 1 to 6, further comprising (E) a bleaching agent.
Item 8. Item 8. The tablet denture cleaner according to any one of Items 1 to 7, further comprising (F) a sugar alcohol.
Item 9. A raw material mixture containing (A) at least one carbonate compound selected from the group consisting of (A) carbonate, hydrogen carbonate, and a double salt of hydrogen carbonate and carbonate, (B) an acid, and (C) an alkyl glycoside. A method for producing a denture cleaner in the form of a tablet, which comprises

  The denture detergent according to the present invention has a wide range of tableting conditions in which no tableting problems occur, so control of the tableting conditions becomes easy, and tableting due to the influence of air temperature fluctuation, raw material condition, etc. Failure can be suppressed. Therefore, the tablet-like denture cleaner of the present invention can suppress the production loss in the tableting process, and can realize high production efficiency in industrial production.

1. Denture cleaner The denture cleaner of the present invention is in the form of a tablet, and is at least one carbonate compound selected from the group consisting of (A) carbonates, bicarbonates, and double salts of bicarbonates and carbonates. And (B) an acid, and (C) an alkyl glycoside. Hereinafter, the denture cleaner of the present invention will be described in detail.

(A) Carbonate Compound The denture cleaner of the present invention contains at least one carbonate compound selected from the group consisting of carbonates, hydrogencarbonates, and double salts of hydrogencarbonates and carbonates. The carbonic acid compound becomes a component of the foaming agent, and reacts with an acid at the time of cleaning of the denture to play a role of generating carbon dioxide gas.

  The carbonate is not particularly limited, and examples thereof include alkali metal salts of carbonic acid such as sodium carbonate and potassium carbonate. Among these, preferably, sodium carbonate is mentioned.

  The hydrogen carbonate is not particularly limited, and examples thereof include alkali metal salts of hydrogen carbonate such as sodium hydrogen carbonate (sodium bicarbonate) and potassium hydrogen carbonate. Among these, preferred is sodium hydrogen carbonate.

The double salt of carbonate and hydrogen carbonate is not particularly limited, and examples thereof include sodium sesquicarbonate and the like.
These carbonic acid compounds may be used alone or in combination of two or more.

  Among these carbonic acid compounds, preferred are sodium carbonate and sodium hydrogen carbonate.

  The content of the carbonated compound in the denture cleanser of the present invention is not particularly limited as long as it can exert a foaming effect when cleaning the denture, but for example, it is 5 to 60% by weight, preferably the total amount of the carbonated compound. 10 to 50 weight%, More preferably, 15 to 50 weight% is mentioned.

(B) Acid The denture cleaner of the present invention contains an acid. The acid becomes a component of the foaming agent, and reacts with the carbonic acid compound when cleaning the denture to generate carbon dioxide gas.

  As the acid, those which are solid at normal temperature are preferably used. The acid may be either an organic acid or an inorganic acid.

  The organic acid is not particularly limited, and examples thereof include citric acid, tartaric acid, fumaric acid, malic acid, maleic acid, gluconic acid, succinic acid, salicylic acid and the like.

  The inorganic acid is not particularly limited, and examples thereof include phosphoric acid and sulfamic acid.

  These acids may be used alone or in combination of two or more. Among these acids, preferred are organic acids, more preferably citric acid and malic acid.

  The content of the acid in the denture detergent of the present invention is not particularly limited as long as it can react with the carbonic acid compound to generate carbon dioxide in water, but for example, the total amount of acid per 100 parts by weight of the total carbonic acid compound 20 to 100 parts by weight, preferably 30 to 90 parts by weight, more preferably 40 to 85 parts by weight.

  Moreover, in the denture detergent of the present invention, the total amount of the carbonic acid compound and the acid (the sum of the content of the carbonic acid compound and the content of the acid) is, for example, 10 to 85% by weight, preferably 20 to 80%. %, More preferably 30 to 75% by weight.

(C) Alkyl Glycoside The denture cleaner of the present invention contains an alkyl glycoside. The alkyl glycosides serve to improve the tabletability and improve the range of tableting conditions (pressure conditions) in which no tableting problems occur in the denture cleaner in the form of a tablet containing the carbonic acid compound and an acid.

  An alkyl glycoside is a compound in which an alcohol is linked to a sugar through a glycosidic bond, and is a compound having a hydrocarbon moiety and a sugar moiety.

  The hydrocarbon moiety constituting the alkyl glycoside may be either linear or branched, and may be saturated or unsaturated, preferably a linear or branched saturated hydrocarbon It can be mentioned. Moreover, it does not restrict | limit in particular about carbon number of the said hydrocarbon part, For example, 8-22, Preferably 10-16, More preferably, 10-14 are mentioned.

  The sugar moiety constituting the alkyl glycoside may be either a monosaccharide, an oligosaccharide or a polysaccharide. The degree of condensation of the sugar moiety (ie, the number of monosaccharides constituting the sugar moiety) is, for example, 1 to 10, preferably 1 to 5, more preferably 1 to 3, still more preferably 1 or 2, particularly preferably Is 1 (ie, the sugar moiety is monosaccharide). Specific examples of the sugar moiety include monosaccharides such as glucose, galactose, xylose, fructose, mannose, lyxose and apibinose; oligosaccharides such as maltose, xylobiose, isomannose, lactose, sucrose, raffinose and maltotriose It can be mentioned. Among these, preferably monosaccharides or disaccharides, preferably monosaccharides, more preferably glucose.

  Specific examples of the alkyl glycoside include alkyl glucosides such as octyl glucoside, decyl glucoside, lauryl glucoside, mystyryl glucoside, palmityl glucoside, stearyl glucoside, oleyl glucoside and the like; octyl glucoside, decyl glucoside, lauryl glucoside, mystyryl glucoside, Alkyl glucosides such as palmityl glucoside, stearyl glucoside, oleyl glucoside; octyl fructoside, decyl fructoside, lauryl fructoside, mystyryl fructoside, palmityl fructoside, stearyl fructoside, oleyl fluoside Alkyl fructosides such as ctoside; octyl maltoside, decyl maltoside, lauryl maltoside, mystyryl maltoside, palmityl maltoside, ste Rirumarutoshido, alkyl maltoside such oleyl maltoside octyl scan black Sid, Deshirusukuroshido, lauryl scan black Sid, Miss Chile Luz black Sid, palmitate dust Angeles black Sid, stearyl scan black glucoside, alkyl scan black Sid such as oleyl black Sid and the like.

  These acids may be used alone or in combination of two or more. Among these alkyl glycosides, from the viewpoint of further broadening the range of tableting conditions in which tableting problems do not occur, preferably, a sugar comprising a hydrocarbon moiety having 10 to 16 carbon atoms and a monosaccharide or a disaccharide Alkyl glucoside having a moiety; more preferably alkyl glucoside having a hydrocarbon moiety having 10 to 16 carbon atoms; still more preferably alkyl glucoside having a hydrocarbon moiety having 10 to 14 carbon atoms; particularly preferably lauryl glucoside It can be mentioned.

  As content of the alkyl glycoside in the denture detergent of this invention, 0.1-3 weight% is mentioned, for example. The content of the alkyl glycoside is preferably 0.5 to 2% by weight, more preferably 1 to 2% by weight from the viewpoint of further widening the range of tableting conditions in which tableting failure does not occur.

(D) Polyalkylene Glycol The denture cleaner of the present invention may contain a polyalkylene glycol in addition to the above components. Polyalkylene glycols serve as a binder and can further broaden the range of tableting conditions without tableting problems.

  The number of carbon atoms of the alkylene group constituting the polyalkylene glycol is not particularly limited, and examples thereof include 2 to 4, preferably 2 or 3, and more preferably 2. The average addition mole number of the alkylene oxide in the polyalkylene glycol is not particularly limited, and for example, 100 to 250, preferably 130 to 230, more preferably 160 to 210 can be mentioned.

  Specific examples of polyalkylene glycols include polyethylene glycol, polypropylene glycol, polybutylene glycol and the like.

  These polyalkylene glycols may be used alone or in combination of two or more. Among these polyalkylene glycols, polyethylene glycol is preferably mentioned from the viewpoint of further widening the range of tableting conditions in which tableting problems do not occur.

  When a polyalkylene glycol is blended to the denture cleaner of the present invention, the content thereof may be, for example, 0.1 to 2% by weight. The content of the polyalkylene glycol is preferably 0.5 to 2% by weight, more preferably 0.5 to 1. In view of widening the range of tableting conditions more effectively free from tableting failure. 5% by weight can be mentioned.

(E) Bleaching agent The cleaning agent of the present invention may optionally contain a bleaching agent. In the denture cleaner of the present invention, when a bleaching agent is contained, it is possible to impart a bleaching action to improve the detergency.

  The type of bleaching agent used in the present invention is not particularly limited as long as it is nontoxic and physiologically acceptable, and those commonly used in denture cleaners can be widely used.

  Examples of the bleaching agent include percarbonate, perborate, persulfate, monohydrogenpersulfate and the like.

  Specific examples of the percarbonate include alkali metal salts of percarbonates such as sodium percarbonate and potassium percarbonate, ammonium percarbonate, and hydrates thereof. Specific examples of the perborate include alkali metal salts of perborate such as sodium perborate and potassium perborate, ammonium perborate, and hydrates thereof. Specific examples of the persulfate include alkali metal salts of persulfate such as sodium persulfate and potassium persulfate, ammonium persulfate, and hydrates thereof. Specific examples of the monohydrogenpersulfate include alkali metal salts of monohydrogenpersulfate such as sodium monohydrogenpersulfate and potassium monohydrogenpersulfate, ammonium monopersulfate, and hydrates thereof. .

  These bleaching agents may be used alone or in combination of two or more. Among these bleaching agents, preferably an alkali metal salt of monohydrogenpersulfate and an alkali metal salt of perborate, more preferably potassium monohydrogensulfate and sodium perborate

  When a bleaching agent is blended into the denture cleaner of the present invention, the content thereof may be appropriately set within a range capable of exhibiting a desired bleaching action, for example, 10 to 40% by weight in total of the bleaching agent, Preferably 10 to 35% by weight, more preferably 13 to 30% by weight can be mentioned.

(F) Sugar alcohol The denture cleaner of the present invention may contain a sugar alcohol in addition to the above components. The sugar alcohol plays a role as a binder, and particularly when used in combination with a polyalkylene glycol, the range of tableting conditions in which tableting failure does not occur can be further broadened.

  The type of sugar alcohol is not particularly limited, and examples thereof include sorbitol, mannitol, xylitol, erythritol and the like.

  These sugar alcohols may be used alone or in combination of two or more. Among these sugar alcohols, preferred is sorbitol.

  When a sugar alcohol is added to the denture cleaner of the present invention, the content thereof is, for example, 1 to 30% by weight, preferably 3 to 20% by weight, more preferably 4 to 15% by weight in total sugar alcohol. Can be mentioned.

(G) Lubricant The denture cleaner of the present invention preferably contains a lubricant in order to facilitate the process of forming into a tablet.

  The type of lubricant is not particularly limited, and examples thereof include magnesium stearate, calcium stearate, sodium stearyl fumarate, sucrose fatty acid ester, sodium lauryl sulfate, talc, light anhydrous silicic acid, hydrous silicon dioxide and the like. .

  These lubricants may be used alone or in combination of two or more. Among these lubricants, preferred are magnesium stearate, calcium stearate, and more preferably magnesium stearate.

  When a lubricant is added to the denture cleaner of the present invention, the content thereof is, for example, 0.01 to 1% by weight, preferably 0.015 to 0.5% by weight, more preferably 0.02 to 0.3 weight% is mentioned.

(H) Surfactants other than alkyl glycosides In addition to their role in extending the range of tableting conditions in which tableting problems do not occur, surfactant alkylglycosides have a surface-active action and also exert a cleaning action on dentures, The denture cleaner of the present invention may not contain a surfactant other than an alkyl glycoside, but preferably contains a surfactant other than an alkyl glycoside to enhance the detergency.

  The types of surfactants (other than alkyl glycosides) to be incorporated into the denture cleaner of the present invention are not particularly limited as long as they can be used as components of the cleaner, and they are cationic, anionic and non-ionic. Any of ionic and amphoteric surfactants may be used.

  Specific examples of the cationic surfactant include quaternary ammonium such as alkyl (C 6 to C 20) trimethyl ammonium salt, dialkyl (C 6 to C 20) dimethyl ammonium salt, and alkyl (C 6 to C 20) dimethyl benzyl ammonium salt. And salts thereof, alkyl (C6-C20) amine salts, alkyl (C6-C20) amine ethylene oxide adducts, alkyl pyridinium salts and the like. One of these cationic surfactants may be used alone, or two or more thereof may be used in combination.

  Specifically as the anionic surfactant, a linear alkyl benzene sulfonate having an alkyl group having an average of 10 to 16 carbon atoms, an alkenyl sulfonate having an average of 10 to 20 carbon atoms in one molecule, an average Straight-chain alkyl sulfoacetate having an alkyl group having 10 to 20 carbon atoms, alkyl sulfate having an alkyl group having an average carbon number of 10 to 20, alkane sulfonate having an average of 10 to 20 carbon atoms in one molecule, etc. Can be mentioned. These anionic surfactants may be used alone or in combination of two or more.

  Specific examples of the nonionic surfactant include higher alcohol ethylene oxide adducts, alkylphenol ethylene oxide adducts, fatty acid ethylene oxide adducts, polyhydric alcohol fatty acid ester ethylene oxide adducts, higher alkylamine ethylene oxide adducts Polyethylene glycol type surfactants such as fatty acid amide ethylene oxide adducts, ethylene oxide adducts of fats and oils, polypropylene glycol ethylene oxide adducts, fatty acid esters of glycerol, fatty acid esters of pentaerythritol, fatty acid esters of sorbitol and sorbitan, Examples include polyhydric alcohol type surfactants such as fatty acid esters of sugars, alkyl ethers of polyhydric alcohols, and fatty acid amides of alkanolamines. It is. These non-ionic surfactants may be used alone or in combination of two or more.

  As the amphoteric surfactant, specifically, an amino acid type surfactant such as an alkylamino propionate having an average carbon number of 10 to 16 (for example, sodium lauryl amino propionate), an average carbon number of 10 to 16 And alkyl betaines (e.g., lauryl dimethyl betaine, stearyl dimethyl betaine, etc.) and betaine type surfactants such as lauryl hydroxyethyl betaine. These amphoteric surfactants may be used alone or in combination of two or more.

  Among the various surfactants described above, the form of the salt includes alkali metal salts such as sodium and potassium, alkaline earth metal salts such as magnesium and calcium, acid addition salts such as ammonium salts, amine salts and hydrochlorides, etc. It can be mentioned.

  Among these surfactants, preferred are anionic surfactants. These surfactants may be used alone or in combination of two or more.

  When a surfactant (other than an alkyl glycoside) is contained in the denture cleaner of the present invention, its content may be appropriately set according to the type of surfactant to be used, the cleaning power to be provided, etc. For example, the total amount of the alkyl glycoside and the surfactant other than the alkyl glycoside is 0.1 to 10% by weight, preferably 0.5 to 5% by weight, more preferably 1 to 4% by weight.

Other Components In addition to the above-described components, the denture cleaner of the present invention may contain other additives as necessary for the purpose of enhancing the detergency, imparting disintegrability, imparting of moldability, etc. It may be

  Other additives that can be incorporated into the denture cleaner of the present invention include rust inhibitors, chelating agents, pH adjusters, enzymes, colorants, sweeteners, foam stabilizers, preservatives, antibacterial and bactericidal agents, preservatives Agents, binders (other than alkylene glycol and sugar alcohol), extenders, excipients, disintegrants and the like.

Formulation form The denture cleaner of the present invention is in the form of a tablet. Formulation to a tablet form can be carried out by a generally employed tableting method. For example, a raw material mixture of a carbonic acid compound, an acid, an alkyl glycoside and other additives optionally mixed may be subjected to a tableting step. Also, prior to the tableting step, the mixture may be granulated in the form of granules, if necessary. In the present invention, since the range of tableting conditions (battering pressure conditions) in which tableting failure does not occur is broadened, control of the tableting conditions becomes easy, and furthermore, the impact due to the influence of temperature fluctuation, raw material condition, etc. Locking problems can be suppressed.

  In the denture cleaner of the present invention, the weight per tablet is not particularly limited and may be appropriately set based on the convenience of use, but the weight per tablet is necessary for one denture wash. It is desirable to set it to a reasonable amount. Specifically, as a weight per denture cleaner of the present invention, 1 to 4 g, preferably 2 to 3 g can be mentioned.

Method of Use The denture cleanser of the present invention can wash dentures by coexistence with a denture to be cleaned in a state of being added to water. In addition, when the denture cleaner of the present invention contains a foaming agent (carbonic acid compound and acid), the foaming agent causes foaming in water to physically stimulate the denture, alkyl glucoside, and as necessary. The denture can be effectively cleaned by the surfactant action by the other surfactant added.

  The water used to wash the denture with the denture cleaner of the present invention is not particularly limited, and examples thereof include tap water, purified water, physiological saline and the like.

  When the denture is cleaned using the denture cleaner of the present invention, the denture cleaner of the present invention may be added after the denture is immersed in water, or after the denture cleaner of the present invention is added to water. May be immersed.

  In denture cleaning, the ratio of denture cleaner to water of the present invention is appropriately set according to the composition of denture cleaner of the present invention, the degree of soiling of dentures to be cleaned, etc. The denture cleaner may be generally used in an amount of about 1 to 10 parts by weight, preferably about 1 to 5 parts by weight, per 100 parts by weight of water. More specifically, in one denture cleaning, 100 to 200 ml of water may be prepared, and 1 to 20 g, preferably 1 to 10 g of the denture cleaner of the present invention may be added thereto.

  The water temperature at the time of denture cleaning may be about 5 to 40 ° C. In addition, the time for immersing the denture in water to which the denture cleaner of the present invention is added is generally about 5 minutes to 12 hours, preferably about 30 minutes to 8 hours.

2. Denture Cleaning Method The denture cleaning method of the present invention is a method of cleaning a denture using the above denture cleaner. That is, the denture cleaning method of the present invention is a method of immersing a denture in water containing the denture cleaner to clean the denture. The specific embodiment of the denture cleaning method of the present invention is as described in the above-mentioned "1. Denture cleaning agent" column.

  EXAMPLES Hereinafter, the present invention will be specifically described by way of examples, but the present invention is not limited to these examples.

In addition, the brand names, the composition, the acquisition source, etc. of the main components used in the following test examples and formulation examples are as follows.
Lauryl glucoside: trade name "Glucopon 50G" (manufactured by BASF Japan Ltd.)
A mixture of potassium sulfate, potassium hydrogen sulfate, and potassium monopersulfate (containing about 43% by weight of potassium monopersulfate) : trade name "OXONE" (Lanxess Co., Ltd.)
Sodium perborate : Brand name "SODIUM PERBORATE MONOHYDRAT" (made by BELINKA)
Polyethylene glycol : trade name "PEG6000P" (manufactured by Daiichi Kogyo Co., Ltd.)
Sodium α-olefin sulfonate : trade name "ASCO-90" (manufactured by Aekyung Specialty Chemicals Co. Ltd.)
Sodium lauryl sulfate : Brand name "Emar 10 PHD" (made by Kao Corporation)

Test Example Using a tableting apparatus (CLEANPRESS Correct Model No. 1518SS7JY, manufactured by Kikusui Seisakusho Co., Ltd.), the raw material mixture having the composition shown in Table 1 was used to change the pressure conditions at the time of pre-compression and at the time of main pressure, respectively 2.65 g). Each tablet obtained was measured for hardness (measured with a Schloin gel hardness tester (tablet hardness tester 6D: made by DR. SCHLEUNIGER PHARMATRON)) and thickness, and the presence or absence of tableting failure (capping, lamination, sticking) Observed. Based on the following judgment criteria, the breadth of the tableting conditions was obtained in which tablets having a hardness of 8 sc or more and a thickness of less than 3.90 mm and neither capping nor lamination was observed (acceptable tablets) were obtained. .
<Criteria for judging tableting conditions to obtain acceptable tablets>
A: As a range of tableting conditions in which a passable tablet can be obtained, the range of filling depth of precompression was 1.5 mm or more, and the range of this pressure was more than 1.5 t.
B: As a range of tableting conditions at which a passable tablet is obtained, the range of filling depth of preload is 1 mm or more and less than 1.25 mm, and the range of main pressure is more than 1.5 t.
C: As a range of tableting conditions under which acceptable tablets can be obtained, the range of filling depth of preload is less than 1 mm, and the range of main pressure is 1.5 t or less.

  The results are shown in Table 1. The tablet containing the effervescent agent (carbonic acid compound and acid) and containing no lauryl glycoside (Comparative Example 1) had a judgment result of C, and the tableting conditions for obtaining an acceptable tablet were narrowed. Moreover, the tableting conditions in which an acceptable tablet is obtained were narrow also with the tablet (comparative example 2 and 3) containing only one of a carbonic acid compound or an acid, and lauryl glycoside. On the other hand, in the tablet (Examples 1 to 6) containing lauryl glycoside together with the foaming agent (carbonic acid compound and acid), the judgment result is A or B, and the tableting conditions for obtaining a passable tablet were broadened. In particular, tablets containing 1% by weight or more of lauryl glycoside and 1% by weight or more of polyethylene glycol together with a foaming agent (carbonic acid compound and acid) (Examples 1 to 3 and 6) have particularly wide tableting conditions for obtaining acceptable tablets. It had become.

Formulation Example The raw material mixture of the composition shown in Table 2 was tableted and molded to obtain a tablet denture cleaner (2.65 g per tablet). All of these denture cleansers had a wide range of tableting conditions without causing tableting problems and were good.

Claims (9)

  A tablet comprising (A) at least one carbonic acid compound selected from the group consisting of (A) carbonates, hydrogencarbonates, and double salts of hydrogencarbonates and carbonates, (B) acid, and (C) alkyl glycosides. Denture Cleaner.   The tablet-like denture cleaner of Claim 1 whose said alkyl glycoside is an alkyl glucoside which has a C8-C22 hydrocarbon part.   The tablet-form denture cleaner of Claim 1 or 2 which contains 0.1 to 3 weight% of said alkyl glycosides.   The tablet denture cleaner according to any one of claims 1 to 3, further comprising (D) a polyalkylene glycol.   The tablet-like denture cleaner according to claim 4, wherein the polyalkylene glycol is polyethylene glycol.   The tablet-form denture cleaner of Claim 4 or 5 which contains 0.1 to 3 weight% of said polyalkylene glycol.   The tablet denture cleaner according to any one of claims 1 to 6, further comprising (E) a bleaching agent.   The tablet denture cleaner according to any one of claims 1 to 7, further comprising (F) a sugar alcohol.   A raw material mixture containing (A) at least one carbonate compound selected from the group consisting of (A) carbonate, hydrogen carbonate, and a double salt of hydrogen carbonate and carbonate, (B) an acid, and (C) an alkyl glycoside. A method for producing a denture cleaner in the form of a tablet, which is subjected to a tableting step.