JP2019090754A - Specimen sediment container for clinical testing and sample sediment method using the same - Google Patents

Abstract

To provide means that allows a specimen sediment to be accurately smeared on a slide glass with a simple operation by easily removing a cervical rubbing material from an operating rod to ensure that the specimen sediment is stored in a container, without fear of falling out or contaminating a collected gynecological specimen, in the case of using a gynecological release device fitted with the cervical rubbing material at a tip of the operation rod.MEANS FOR SOLVING THE PROBLEM: The instrument includes a cylindrical container body 1 whose both ends are open, a specimen sediment smearing stopper 2 detachably fitted to one end opening 1a, and a cap 3 mounted on another end opening 1b, and is equipped with a sediment deposition plate part 21 for depositing the specimen sediment in the container body 1 at an inner end of the specimen sediment smearing stopper 2. The container body 1 is made of flexibly elastic and transparent polymeric material of which a peripheral wall part 10 is depressibly deformable by pressing with fingers.SELECTED DRAWING: Figure 1

Description

  The present invention relates to a sample sediment container used for clinical examination, in particular, a container suitable for sediment of collected cells by a gynecological peeling tool used for cervical cancer screening, and a sample sediment method using the container.

  In clinical examinations such as cervical cancer examinations, as liquefaction sample cytology, examination cells are prepared by smearing sample cells sedimented from a storage solution by centrifugation on a slide glass, and examination by microscopic observation is performed. In the old days, as a means for depositing sample cells, a tubular container called a centrifuge tube (for example, Patent Document 1) is used, and the sample cells are dispersed in the storage solution contained therein and centrifuged. It is common to deposit sample cells in the bottom of the container.

  However, when using the above-mentioned centrifuge tube, sample sediment on the inner bottom of the container is collected by sucking it up with a droper, and this is dropped onto a slide glass, and the troublesome work of spreading the sediment thinly with another slide glass etc. is necessary. In particular, when the amount of sediment is small, very careful operation is required to be inefficient, and there is also a problem that mutual contamination is likely to occur in a series of operation processes.

  Therefore, the present applicant first uses a cylindrical container main body with both ends opened as a sample sediment container replacing the conventional centrifuge tube, a sample sediment smearing cover to be fitted to the one end side opening portion, and others. It is proposed to be equipped with a sediment deposition tray at the inner end of the plug part which is made up of a cap attached to the end side opening and which the sample sediment smearing cover is pressed into within the container body (Patent Document 2) ). In this sample sediment container, the storage liquid in which the sample is dispersed is contained in the container main body in which the one end side opening is sealed with the sample sediment smearing lid, and the other end side opening is attached with a cap. The sample is centrifuged as in the case of the centrifuge tube, but the centrifuged sample sediment is deposited on the sediment deposit portion of the sample sediment smearing lid. Therefore, the test sediments can be placed on the slide glass by a simple operation of detaching the sample sediment smearing cover from the container body after centrifugation and pressing the sediment deposition plate portion of the sample sediment smearing cover onto the slide glass. The sample sediment can be smeared accurately with a fluid as in the case of using a traditional centrifuge tube, and it is not necessary to do the troublesome work of spreading it further on a slide glass by dripping it on a slide glass, and the entire amount is small even with a small amount of sediment. There is also an advantage that the smearing operation can be performed efficiently in order to surely deposit on the sediment deposit tray, and since the operation is simple and completed in a short time, mutual contamination is less likely to occur.

  On the other hand, in recent years, as shown in Patent Document 2 as a gynecological peeling tool used for cervical cancer screening, a uterine cervix consisting of a soft synthetic resin brush and an alveolar body at the tip of a handle (handle). It is becoming more and more used that the rubbing material is detachably fitted. When such a gynecological peeling tool is used, after the cervix is abraded with the cervix rubbing material to collect a gynecological specimen (cells), the cervical scraping material is removed from the operating rod and the old one is removed The gynecological sample adhering to the cervical scraping material is placed in the preservation solution by placing it in a centrifuge tube of the above-mentioned sample sediment container and immersing it in the preservation solution and wearing the cap as it is and subjecting it to centrifugation. It will be released, and it will be made to deposit by a specific gravity difference with preservation solution.

Unexamined-Japanese-Patent No. 2004-271309 Patent No. 6025514

  However, with the above-mentioned gynecological peeling tool, when removing the cervical scraper from the operation rod after collection of a gynecological sample, a part of the gynecological sample attached by the movement tends to fall off very carefully. Although the operation is required, there is also concern that contamination from the surrounding atmosphere may occur during the operation, or cross contamination may be caused by picking the cervical scraper. In addition, in order to prevent the fallout and contamination of the above-mentioned gynecological specimens, insert the cervical abrasive side into the container, and clamp the base of the cervical abrasive with the container opening edge using a cap In this state, the method of pulling out the operating rod is also introduced, but in addition to being difficult in operation, it takes time and effort and often fails in operation.

  In the present invention, in view of the above-mentioned circumstances, when using a gynecological peeling tool in which a cervix-abrasive material is fitted to the tip of the operating rod, dropout of the collected gynecological sample after collection of the gynecological sample The cervical scraping material can be easily removed from the operating rod and contained securely in the container without concern that contamination may occur so that sample sediment can be performed, and the test sediment can be accurately smeared on the slide glass by a simple operation. It is an object of the present invention to provide a sample sediment container for clinical examination which makes it possible, and a sample sediment method using the same.

  In order to achieve the above object, the specimen sediment container for clinical examination according to the invention of claim 1 is shown by attaching the reference numeral of the drawing, and the cylindrical container body 1 opened at both ends, and one end side opening thereof The sample sediment smearing plug 2 detachably fitted to the portion 1a and the cap 3 attached to the other end side opening 1b, and the container main body at the inner end of the sample sediment smearing plug 2 The container body 1 is characterized in that the peripheral wall 10 is made of a flexible, elastic and transparent polymer material which can be dented and deformed by finger pressure. .

  According to the invention of claim 2, in the sample sediment container for clinical examination of the above-mentioned claim 1, the stopper body 2 for smearing a sample sediment is made of rubber, and the sediment deposition tray portion 21 has a bowl shape and A plurality of ribs 21a along the inclination direction is formed on the circumferential surface.

  According to the invention of claim 3, in the sample sediment container for clinical examination according to claim 1 or 2, the stopper for smearing a sample sediment is integrally formed with the sleeve 22 at the outer end side, and one end side opening of the container main body 1 In a state of being fitted to 11, the sleeve 22 is configured to be folded outward so as to be in close contact with the outer peripheral surface of the container main body 1.

  The invention according to claim 4 relates to the sample sediment container for clinical examination according to any one of claims 1 to 3, wherein the container body 1 has a constriction portion 11 near one end side, and the one end side opening portion from the constriction portion 11 A thick-walled cylindrical portion 12 is formed up to 1a, and the stopper for smearing sample deposits is inserted into the thick-walled cylindrical portion 12, and the outer periphery of the sediment deposition tray 21 closely contacts the inner circumference of the thick-walled cylindrical portion 12. It is configured to

  The sample sediment method according to the invention of claim 5 is such that the sample sediment container R for clinical examination according to any one of the above claims 1 to 4 and the cervical abrasion members 41 and 42 can be detached from the tip of the operation rod 40 A gynecological specimen attached to the cervical abrasives 41 and 42 of the gynecological peeling tool 4A, 4B using the gynecological peeling tool 4A, 4B fitted in the In a state where the sample sediment smearing plug 2 is fitted to the one end side opening 1a of the container main body 1, the gynecological remover 4A, 4B is a cervical scraping material from the other end side opening 1b of the container main body 1 After inserting from 41 and 42 sides, the middle part of the container main body 1 is pinched and pressed with both fingers from both sides, and the uterine cervix located inside between the side walls 10 and 10 on both sides of the container main body 1 deformed by recess. The base 01a, 42b of the part rubbing material 41, 42 is pinched, and in this pinching state, the operating rod 0 is pulled out to leave the cervical scraping materials 41 and 42 in the container main body 1, and the cervical scraping materials 41 and 42 are immersed in the specimen preservation solution L injected into the container main body 1, and 3 and liquid-seal the inside of the container R, and subjecting the sample sediment container R for clinical examination to centrifugation, the gynecological specimen adhering to the cervical scraping material 41, 42 is stored as the preservation solution L It is characterized in that it is liberated therein and sedimented to be deposited on the sediment deposition tray portion 21 of the stopper 2 for smearing a sample sediment.

  According to the invention of claim 6, according to the sample sedimentation method of claim 5, the cervix rubbing material 41 of the gynecological remover 4A is made of a soft synthetic resin brush.

  According to the invention of claim 7, according to the sample sedimentation method of claim 5, the cervix-abrasive material 42 of the gynecological remover 4B is made of the asbestos body 42a.

  Next, the effects of the present invention will be described with reference to the drawings. The sample sediment container R for clinical examination according to the invention of claim 1 comprises a cylindrical container body 1 open at both ends, a plug 2 for smearing sample sediment fitted in the one end side opening 1a, and the other end Although the peripheral wall 10 of the container body 1 is made of a flexible, elastic and transparent polymer material which can be dented and deformed by finger pressure, the operation rod 40 is composed of the cap 3 attached to the side opening 1b. When a gynecological sample is collected using the gynecological peeling tool 4A, 4B in which the cervical scraping material 41, 42 is detachably fitted to the tip of the sample, the sample is collected in the one end side opening 1a of the container main body 1 After inserting the gynecological remover 4A, 4B from the other end side opening 1b of the container main body 1 from the cervix-abrasive material 41, 42 in a state where the sediment smear plug 2 is fitted, the container main body Inside the cervix rubbing material 41, 42 through the transparent peripheral wall portion 10 of FIG. By visually pressing the middle portion of the container body 1 with fingers from both sides and pressing it, the cervical scraping material 41 located inside between the side walls 10 and 10 on both sides of the container body 1 deformed by denting The base portions 41a and 42b of 42 can be pinched, and in this pinched state, the operating rod 40 can be easily removed. Therefore, even if a part of the gynecological sample adhering to the cervical scraping material 41, 42 drops off due to the movement at the time of the extraction operation, it only falls within the sample sediment container R, so the amount of the sample sediment decreases It is possible to take in the cervix scraping materials 41 and 42 after sample collection into the sample sediment container R quickly with extremely simple operation. Therefore, there is almost no concern that contamination from the surrounding atmosphere occurs during operation, and there is no risk of cross contamination caused by pinching the cervical surface as in the prior art.

  And, in this specimen sediment container R for clinical examination, since the sediment deposition tray 21 for depositing the specimen sediment in the container main body 1 is provided at the inner end of the specimen sediment smear plug 2, storage fluid injected into the container The gynecological sample adhering to the cervical scraping material 41, 42 is liberated and sedimented in the storage fluid L by centrifuging while immersing the cervical scraping material 41, 42 in the The entire amount is deposited on the sediment deposition tray 21. Therefore, after centrifuging, after removing the cap 3 and discharging the preservation solution L, it is a simple matter of removing the stopper 2 for smearing the sample sediment from the container body 1 and pressing the sediment deposition tray 21 on the slide glass G. It is possible to smear the test sediment precisely on the slide glass G by the operation, suck the sample sediment with a droplet like in the old centrifuge tube, drop it on the slide glass, and spread it further thinly. It is possible to perform the smearing operation efficiently in order to ensure that the entire amount is deposited on the sediment deposition tray even if the amount of sediment is small without requiring the

  According to the invention of claim 2, the stopper for smearing a sample sediment is made of rubber, and the sediment depositing plate portion 21 has a bowl shape, and a plurality of ribs 21a along the inclination direction on the bowl-like inner peripheral surface. The specimen sediment is spread thinly on the slide glass G in such a manner that the diameter of the sediment deposition dish 21 is expanded when the sediment accumulation tray 21 on which the specimen sediment is deposited is pressed onto the slide glass G. When the sediment deposition tray 21 is pulled away from the slide glass G, the plurality of ribs 21a are prevented from sucking in a sucker shape.

  According to the invention of claim 3, in a state in which the sample sediment smearing plug 2 is fitted to the one end side opening 11 of the container main body 1, the sleeve 22 on the outer end side is folded outward and the outer periphery of the container main body 1 Since it can be brought into close contact with the surface, the one end side opening 11 of the container body 1 is reliably sealed in a liquid tight manner, and no liquid leakage occurs even if a large load is applied at the time of centrifugal separation.

  According to the invention of claim 4, the stopper body 2 for smearing the sample sediment is provided in the thick-walled cylindrical portion 12 from the constricted portion 11 to the one end-side opening portion 1a. Since the outer periphery of the sediment deposition tray 21 is in close contact with the inner periphery of the thick-walled cylindrical portion 12 as it is inserted, the cervical scrapers 41 and 42 are formed at the tip of the operating rod 40 described above. A gynecological specimen is collected using the fitted gynecological dissection device 4A, 4B, and the cervix abrasives 41, 42 are inserted into the container, and the middle portion of the container body 1 is pressed with fingers from both sides When sandwiching the bases 41a and 42b of the cervical scraping materials 41 and 42, the thick-walled cylindrical portion 12 is not easily deformed, so the fitting state of the sample sediment smearing plug 2 is loosened to cause sealing failure. There is no concern, and when the outer periphery of the sediment deposition tray 21 is in close contact with the inner periphery of the constricted portion 11, The amount reliably deposited 該沈 residue deposit pan 21.

  According to the sample sediment method according to the invention of claim 5, the specimen sediment container R for clinical examination according to any one of claims 1 to 4 and the cervical scraping members 41 and 42 at the tip of the operation rod 40 A gynecological sample is attached to the cervical abrasives 41 and 42 of the gynecological peeling tool 4A, 4B using the gynecological peeling tool 4A, 4B detachably fitted, and the sample sediment container for clinical examination In a state where the sample sediment smearing plug 2 is fitted to the one end side opening 1a of the container body 1 of R, the gynecological remover 4A, 4B is inserted into the cervix from the other end side opening 1b of the container body 1 After inserting from the side of the abrasives 41, 42, the middle portion of the container body 1 is pinched and pressed with both fingers from both sides, so that it is inside between the side walls 10, 10 on both sides of the container body 1 deformed by recess. With the bases 41a and 42b of the cervical scraping materials 41 and 42 held in this state, The Sakubo 40 can be withdrawn easily. Therefore, even if a part of the gynecological sample adhering to the cervical scraping material 41, 42 drops off due to the movement at the time of the extraction operation, it only falls within the sample sediment container R, so the amount of the sample sediment decreases It is possible to take in the cervix scraping materials 41 and 42 after sample collection into the sample sediment container R quickly with extremely simple operation. Therefore, there is almost no concern that contamination from the surrounding atmosphere occurs during operation, and there is no risk of cross contamination caused by pinching the cervical surface as in the prior art.

  Thus, the cervix abrasives 41 and 42 remain in the container main body 1 from which the operation rod 40 has been removed, so that the specimen storage fluid L is injected into the container main body 1 to immerse the cervix abrasives 41 and 42 Above, the cap 3 is attached, the inside of the container R is sealed in a fluid-tight manner, and the sample sediment container R for clinical examination is subjected to centrifugation to adhere to the cervix abrasives 41, 42 Can be liberated and sedimented in the stock solution L and deposited on the sediment deposition tray 21 of the stopper 2 for smearing sample sediment. Therefore, after centrifuging, after removing the cap 3 and discharging the preservation solution L, it is a simple matter of removing the stopper 2 for smearing the sample sediment from the container body 1 and pressing the sediment deposition tray 21 on the slide glass G. It is possible to smear the test sediment precisely on the slide glass G by the operation, suck the sample sediment with a droplet like in the old centrifuge tube, drop it on the slide glass, and spread it further thinly. It is possible to perform the smearing operation efficiently in order to ensure that the entire amount is deposited on the sediment deposition tray even if the amount of sediment is small without requiring the

  In addition, as a gynecological peeling tool, the cervical scraping material 41 defined in claim 7 is made of a soft synthetic resin brush, and the cervical scraping material 42 defined in claim 8 is a cotton swab 42a. Preferred are those comprising

It is a semi-longitudinal front view of a sample sediment container for clinical examinations concerning one embodiment of the present invention. It is a longitudinal cross-sectional front view of the principal part which shows fitting operation of the stopper body for smear sample deposits with respect to the container main body of the sample sediment container for the same clinical test. It is a perspective view of the stopper body for smear deposits of the same sample. It is a perspective view which shows the front end side of the brush type gynecological remover applied to the sample sediment container for the clinical examinations. It is a perspective view which shows the front end side of the cotton swab type gynecological remover applied to the sample sediment container for clinical examinations. It is a principal part longitudinal front view which shows the operation stick extraction operation of the brush type gynecological remover in the sample sediment container for the clinical examinations. The state which stored the cervix abrasion material of the exfoliation tool for gynecology in the sample sediment container for the same clinical examination is shown, (a) is a longitudinal cross-sectional front view in case the cervix abrasion material is a soft synthetic resin brush, b) is a longitudinal front view in the case where the cervix-abrasive material is asbestos; Fig. 6 shows an operation of smearing on a slide glass a gynecological sample deposited on a sediment deposition plate portion of the same sample sediment smearing plug, wherein (a) is a longitudinal front view before pressing, (b) is a longitudinal front view at pressing It is.

  Hereinafter, embodiments of a specimen sediment container for clinical examination and a specimen sediment method using the same according to the present invention will be specifically described with reference to the drawings.

  As shown in FIG. 1, the specimen sediment container R for clinical examination has a substantially cylindrical container main body 1 opened at both ends, and a stopper 2 for smearing a specimen sediment detachably fitted to the one end side opening 1a. And a cap 3 attached to the other end side opening 1b.

  The container body 1 is made of a flexible, elastic and transparent polymer material whose peripheral wall portion 10 can be recessed and deformed by finger pressure, and has a constricted portion 11 near one end side, and the one end side opening portion from the constricted portion 11 While forming a thick cylindrical portion 12 expanded in diameter toward 1a, a flange portion 13 is formed on the outer periphery from the other end side, and a male screw 14 is formed on the outer periphery from the flange portion 13 to the other end side opening 1b. It is set up. Then, as shown in an enlarged view in FIG. 2, an annular flange 11 a is formed on the inner periphery of the constricted portion 11, and a locking step 12 a continuous in the circumferential direction is formed on the outer periphery on the tip end side of the thick cylindrical portion 12. It is provided.

  The sample sediment smearing plug 2 is made of flexible rubber, and as shown in FIG. 3, the plug body 20 having a substantially short cylindrical shape and a trumpet-shaped protrusion provided on the inner end side of the plug body 20. The sediment deposition tray 21 and the thin cylindrical sleeve 22 extending axially outward from the outer periphery of the plug portion 20 are formed. The plug body portion 20 has a space portion 20a opened to the outer end side, and an annular step portion 20b is formed on the outer periphery of the axially intermediate portion. In addition, the sediment deposition plate portion 21 has a bowl shape, and on the bowl-like inner peripheral surface, a plurality of thin ribs 21a along the inclination direction and a plurality of low and thin annular convex members arranged at equal intervals in the depth direction. Article 21b is formed. Furthermore, an engaging flange 22 a is formed at the peripheral edge of the sleeve 22.

  As shown in FIGS. 1 and 2, the stopper 2 for smearing a sample sediment is inserted into the thick-walled cylindrical portion 12 from the one end side opening 1 a of the container main body 1 so that the stepped portion 20 b is formed. And the peripheral edge of the sediment deposition tray 21 abuts on the annular flange 11a on the inner periphery of the container body 1, and the outer periphery of the sediment deposition tray 21 is thick. Close to the inner circumference of the meat cylinder 12. Then, in this inserted state, the sleeve 22 is folded outward as shown by the arrow in FIG. 2 so that the sleeve 22 is in close contact with the outer peripheral surface of the container main body 1 as shown by the imaginary line in FIG. The hook portion 22a engages with the locking step portion 12a of the container body 1, so that the sample sediment smearing plug 2 is engaged with the container body 1 so as not to be withdrawn.

  The cap 3 is made of a hard synthetic resin molded product, and as shown in FIG. 1, the other end of the container body 1 is screwed and tightened to the external thread 14 of the container body 1 by screwing the female screw 3 a The side opening 1b is closed. Although packing is not inserted in the inner part of the cap 3, since the container main body 1 is made of a flexible elastic polymer material, the other end side opening 1b is reliably sealed by mounting the cap 3 It is stopped.

  Here, the polymer material constituting the container body 1 is not particularly limited as long as it is flexible, elastic and transparent, and is generally selected from butadiene rubber, isoprene rubber, chloroprene rubber, fluororubber, silicone rubber, etc. In addition to various rubber materials, various thermoplastic elastomers (TPE) are also included, but those excellent in impact resilience and water resistance are recommended.

  In cervical cancer screening, for example, a brush-type gynecological peeling tool 4A as shown in FIG. 4 is generally used for collection of gynecological samples, but a cotton-rod-type gynecological department as shown in FIG. 5 The peeling tool 4B is also used. The former brush-type gynecological remover 4A is composed of two members, an operating rod 40 made of a hard synthetic resin and a cervical abrasive 41 made of a soft synthetic resin brush, provided at the tip of the operating rod 40 The small-diameter projecting shaft portion 40 a is press-fitted and integrated with the tubular base portion 41 a of the cervical scraping material 41. The cervical scraping material 41 has a structure in which a plurality of brush portions 41c made of soft wire bodies are provided on the front surface of the blade-like substrate portion 41b integral with the proximal end cylindrical portion 41a. On the other hand, the latter cotton swab type gynecological dissection device 4B is composed of two members of a similar operating rod 40 and a cervical abrasion material 42 consisting of an asbestos body 42a. The tip of the operation rod 40 is press-fitted and integrated with a cylindrical base portion 42b made of a soft synthetic resin to which the body 42a is fixed.

  When the sample sediment container R for clinical examination of the present invention described above is used for clinical examination of cervical cancer screening, for example, in a brush-type gynecological dissection device 4A, the gynecological specimen is attached to the cervical scraping material 41 Then, with the sample sediment smearing plug 2 fitted in the one end side opening 1a of the container body 1 of the sample sediment container R, with the other end side opening 1b up with the cap 3 removed, the left hand And the gynecological dissection device 4A held by the right side from the other end side opening 1b are inserted from the cervix rubbing material 41 side. Then, as shown in FIG. 6, the middle portion of the container body 1 is pinched and pressed from both sides by the thumb FL1 of the left hand and the forefinger FL2 and the middle finger FL3 so that the side walls of both sides of the container body 1 deformed by dents The base 41a of the cervix rubbing material 41 is held between 10 and 10, and in this holding state, the operation rod 40 gripped with the thumb FR1 of the right hand, the index finger FR2 and the middle finger FR3 is pulled upward as shown by the arrow. The operating rod 40 is pulled out of the cervix abrasive 41. In addition, although illustration is abbreviate | omitted, also in the case of the cotton-tack type gynecological remover 4B, the operating rod 40 should just be extracted from the cervix abrasion material 42 by the same operation.

  As described above, when the specimen sediment container R for clinical examination of the present invention is used, even if a part of the gynecological specimen adhering to the cervix abrasives 41 and 42 falls off due to the movement at the time of the extraction operation of the operation rod 40, Since it falls into the sample sediment container R, it does not lead to a reduction in the amount of sample sediment, and contamination of the periphery due to dropped out samples is avoided, and the cervical scraping materials 41 and 42 after sample collection is extremely simple. Since the sample sediment container R can be quickly taken into operation by any operation, there is little concern that contamination from the surrounding atmosphere will occur during operation, and it is caused by picking up the cervical scraping material 41, 42 as in the prior art. There is no risk of cross contamination. The thick-walled cylindrical portion 12 of the container main body 1 is a thick, short, small-diameter cylindrical shape and is hard to be deformed. Therefore, as described above, the middle part of the container main body 1 is pressed with a finger to scratch the cervix When sandwiching the base portions 41a and 42b of the members 41 and 42, there is no concern that the fitting state of the sample sediment smearing plug 2 is loosened to cause sealing failure.

  Thus, the cervix rubbing members 41 and 42 remain in the container main body 1 from which the operation rod 40 has been removed, and therefore, as shown in FIGS. 7A and 7B, the specimen storage fluid L is injected into the container main body 1 Then, the cervix abrasives 41 and 42 are immersed, the cap 3 is attached, the inside of the sample sediment container R is fluid-tight sealed, and the specimen sediment container R is centrifuged to separate the cervix. The gynecological sample adhering to the abrasives 41 and 42 can be liberated and sedimented in the storage fluid L and deposited on the sediment deposition tray 21 of the stopper 2 for smearing a sample sediment.

  After this centrifugation, after removing the cap 3 and discharging the preservation solution L, the stopper 2 for smearing sample sediment is removed from the container main body 1. In the removal, the engagement sleeve 22a of the sample sediment sticking plug 2 is pulled away from the outer periphery of the container main body 1 and inverted so that the engagement step 22a of the container main body 1 is stopped. Then, the stopper 20 can be easily removed from the thick-walled cylindrical portion 12 of the container body 1 and it is extremely easy to operate.

  The specimen sediment smearing plug 2 removed from the container main body 1 is brought into contact with the slide glass G with the sediment deposition tray 21 facing downward as shown in FIG. 8A, and then shown in FIG. 8B. The sample sediment (gynecological specimen = collected cells) deposited on the sediment deposition tray 21 can be accurately smeared on the slide glass G by a simple operation such as pressing as described above. Therefore, it is not necessary to take the troublesome work of sucking up the sample sediment with a fluid and dripping it on a slide glass and spreading it thinner as in the case of using a conventional centrifuge tube, and the entire amount is reliably deposited on the sediment deposition plate even with a small amount of sediment. It can be smeared efficiently to deposit.

  Although the sediment deposition plate portion 21 has a bowl shape, when it is pressed onto the slide glass G as shown in FIG. 8 (b), ventilation between the inside and the outside is secured by the ribs 21a along the inclination direction, so like a suction cup. It can be easily detached from the slide glass G without sticking to the slide glass G. In addition, since a plurality of low thin annular ridges 21b are provided on the bowl-shaped inner surface of the sediment deposition tray 21, deposition is performed even when the sediment deposition tray 21 is directed downward for smearing on the slide glass G. Flowing down of the sample sediment is avoided.

  The stopper 2 for smearing a sample sediment in the specimen sediment container R for clinical examination of the present invention is illustrated in the above embodiment as having the sleeve 22 which is folded outward and engaged with the container main body 1. What is held by the container body 1 by the friction force of the plug portion 20 by press fitting and the elastic force of the rubber material, or the uneven fit between the inner periphery of the container body 1 and the outer periphery of the plug portion 20 It is also possible to use one that is held by the container body 1 by a mating portion (e.g., fitting of a circumferential ridge and groove, etc.). In the present invention, the detailed configuration of the container body 1, the stopper 2 for smearing a sample sediment, the detailed shape of the cap 3 and the like can be variously changed in design except for the embodiment. On the other hand, the gynecological dissection device to be applied to the present invention is not limited to the illustrated brush type and cotton swab type, and any structure may be used as long as the operation rod and the cervix abrasion material are detachably connected. Further, as the brush-type gynecological peeling tool, ones having variously different brush shapes can be applied.

DESCRIPTION OF SYMBOLS 1 container main body 1a one end side opening 1b other end side opening 10 peripheral wall 11 constriction 12 thick-walled cylinder 2 stopper for smearing sample sediment 20 plug body 21 sediment sedimentation tray 21a rib 22 sleeve 3 cap 4A brush type Gynecological Peeling Tools 4B Cotton swab-type Gynecological Peeling Tools 40 Operating rod 41, 42 Cervical scraping material 42a Abrasives G Slides L Storage fluid R Sample sediment container for clinical examination

Claims (7)

The sample sediment is constituted of a cylindrical container main body opened at both ends, a stopper for smearing a sample sediment detachably fitted to the one end side opening, and a cap attached to the other end side opening, The inner end of the smear plug is provided with a sediment depositing tray for depositing sample sediment in the container body,
The sample sediment container for clinical examination characterized in that the container body is made of a flexible, elastic, and transparent polymer material whose peripheral wall portion is dented and deformable by finger pressure.   The stopper for smearing a sample sediment is made of rubber, and the sediment depositing plate portion has a bowl shape, and a plurality of ribs along the inclination direction are formed on the bowl-like inner peripheral surface. Sample sediment container for clinical examination as described.   In the sample sediment smearing plug, a sleeve is integrally formed on the outer end side, and in a state of being fitted to an opening at one end side of the container body, the sleeve is folded outward and closely attached to the outer peripheral surface of the container body The specimen sediment container for clinical examination according to claim 1 or 2, which is configured to obtain.   The container body has a constriction near one end, the thick part from the constriction to the one end opening forms a thick cylindrical part, and the sample sediment smearing plug is inserted into the thick cylindrical part. The specimen sediment container for clinical examination according to any one of claims 1 to 3, wherein an outer periphery of the sediment depositing tray portion is in close contact with an inner periphery of the thick-walled cylindrical portion. A sample sediment container for clinical examination according to any one of claims 1 to 4 and a gynecological peeling tool in which a cervical abrasive is releasably fitted to the tip of a control rod,
Attach a gynecological sample to the cervical scraping material of a gynecological remover,
In a state in which the stopper for smearing sample sediment is fitted to one end side opening portion of the container body of the specimen sediment container for clinical examination, the gynecological peeling tool is a cervical scraping material from the other end side opening portion of the container body After inserting from the side,
By pinching and pressing the middle part of the container body from both sides with fingers, the base of the cervical abrasive material located inside between the recessed and deformed side walls of the container body is clamped, and in this clamping state Withdrawing the operating rod to leave a cervical scraper in the container body,
After immersing the cervical scraping material in the sample storage solution injected into the container body, the cap is attached and the inside of the container is sealed in a liquid-tight manner.
By subjecting the sample sediment container for clinical examination to centrifugation, the gynecological sample adhering to the cervical scraping material is released into the storage solution and sedimented, and the sediment of the plug for smearing the sample sediment is deposited. A method for depositing a sample, characterized in that it is deposited on a part.   The method according to claim 5, wherein the cervical scraping material of the gynecological remover comprises a soft synthetic resin brush.   The method according to claim 5, wherein the cervical scraping material of the gynecological remover comprises an alveolar body.

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