JP2019075046A - Hospital information system and medicine proposition selection program - Google Patents

Abstract

To allow a doctor to provide information about a better new treatment for a patient to the patient when the doctor examines the patient.SOLUTION: The hospital information system includes a processor and a terminal device. The processor selects an investigational new drug and/or an unapproved medicine that are/is desirable for a patient based on individual information and patient medical information of a patient stored in a first database and information on the investigational new drugs and unapproved medicines stored in the second database. The terminal device is connected by the processor and the in-hospital network, and displays the investigational new drug and/or the unapproved medicine selected by the processor to a doctor for introducing it to the patient when the doctor examines the patient.SELECTED DRAWING: Figure 1

Description

  Embodiments of the present invention relate to a hospital information system and a drug proposal selection program.

  There has been proposed a technique for referring to examination results such as receipts and electronic medical records, and searching for information on disease names and corresponding medicines input from a doctor. This type of technology can help physicians prescribe appropriate medications. However, the information provided is a standard drug for the patient's disease and is likely to be already used in therapy. It is assumed that the phase in which the physician and the patient seek new treatment information is when there is no improvement even after continuing standard treatment. As such, the information provided by the prior art may not be sufficient.

  In addition, when patients are going to receive treatment with investigational drugs or domestic unapproved drugs, it is common for patients to search for investigation / unapproved drug disclosure information of independent administrative corporation jurisdiction themselves or to receive referrals from medical institutions. It is. Therefore, the ability of patients to receive treatment with investigational drugs or domestic non-approved drugs according to their own needs largely depends on the information gathering ability of patients and medical institutions.

JP, 2010-128718, A

  Therefore, the purpose is to enable the doctor to provide the patient with new treatment information suitable for the patient at the time of medical treatment.

  According to an embodiment, the hospital information system comprises a processing device and a terminal device. The processing device matches the patient-suitable investigational drug and the patient-suitable investigational drug based on the personal information and patient medical information on the patient stored in the first database and the information on the investigational drug and the non-approved drug stored in the second database. And / or select an unapproved drug. The terminal device is connected to the processing device by an in-hospital network, and when a doctor examines a patient, the investigational drug and / or an unapproved drug selected by the processing device is introduced for the introduction to the patient. Display to doctor.

FIG. 1 is a block diagram showing an environment in which a hospital information system according to the first embodiment is used. FIG. 2 is a block diagram showing a functional configuration of a processing server of the electronic medical record system shown in FIG. FIG. 3 is a flowchart showing an operation when the processing circuit of the processing server shown in FIG. 2 creates proposal information. FIG. 4 is a flow chart showing a subroutine of the determination of body condition matching shown in FIG. FIG. 5 is a flowchart showing a subroutine of social condition conformity determination shown in FIG. FIG. 6 is a view showing a display example of a terminal device of the electronic medical chart system shown in FIG. FIG. 7 is a diagram showing summary information about an investigational drug displayed on the terminal device of the electronic medical chart system shown in FIG. FIG. 8 is a diagram showing detailed information about a study drug displayed on the terminal device of the electronic medical chart system shown in FIG. FIG. 9 is a diagram showing a form for entering a reason for non-introduction, displayed on the terminal device of the electronic medical record system shown in FIG. FIG. 10 is a diagram showing an example of utilization of introduction history information. FIG. 11 is a diagram showing another example of utilization of introduction history information. FIG. 12 is a block diagram showing another configuration example of the hospital information system shown in FIG.

  Embodiments will be described below with reference to the drawings.

First Embodiment
FIG. 1 is a block diagram showing an example of an environment where the hospital information system 10 according to the first embodiment is used. In FIG. 1, a hospital information system 10, an investigational drug / non-approved drug information management server 20, a domestic health institution 30, a pharmaceutical enterprise 40, an overseas health institution 50, a medical institution 60, and an overseas pharmaceutical enterprise 70 are connected by an IP network. There is.

  The hospital information system 10 shown in FIG. 1 is, for example, a system built on an in-hospital network. The hospital information system 10 includes, for example, an electronic medical record system 11, a medical information management server 12, a medical accounting system 13, a radiation department system 14, a clinical examination department system 15, a medical image management system 16, and an image examination apparatus 17. . The hospital information system 10, the electronic medical record system 11, the medical information management server 12, the medical accounting system 13, the radiation department system 14, the clinical examination department system 15, the medical image management system 16, and the image examination apparatus 17 are LAN (Local Area Network). Data communication is possible via an in-hospital network such as

  The connection to the hospital network may be either a wired connection or a wireless connection. Also, as long as security is ensured, the connected line is not limited to the in-hospital network. For example, connection may be made to a public communication line such as the Internet via a VPN (Virtual Private Network) or the like. Also, the system connected to the in-hospital network is not limited to the above. The in-hospital network may include systems other than the above.

  The electronic medical record system 11 is a system that manages information related to the electronic medical record. The information on the electronic medical record includes, for example, patient information, medical care information, and nursing information. The patient information includes, for example, patient ID, patient name, address, age, gender, height, weight, contraindication information, hospital use transportation, and economic situation. The medical care information includes, for example, first recorded information, second recorded information, and the like. In the present embodiment, the first recorded information records information generated at the time of medical care, such as, for example, diseases, symptoms, medical history, findings, diagnoses, and plans. Further, in the present embodiment, the second record information records information generated in conjunction with an order, such as prescription, examination, injection, and treatment. The nursing information includes, for example, nursing implementation record information and the like.

  The medical accounting system 13 is a system that manages information related to a medical treatment fee request. The information related to the medical treatment fee request includes, for example, the medical expenses unpaid situation at the medical institution.

  The radiation department system 14 is a system that manages information such as examination orders and examination reservations in the radiation department which is one of medical care departments.

  The clinical examination department system 15 is a system that manages order information for examining a sample collected by various methods, information on a report created based on a diagnosis result, and the like.

  The medical image management system 16 is, for example, a so-called PACS (Picture Archiving and Communication System) that manages medical images such as radiological examination images, ultrasound images, MRI (Magnetic Resonance Imaging) images, and endoscopy images. . In the medical image management system 16, medical image data is managed, for example, in accordance with the DICOM (Digital Imaging and Communication Medicine) standard. The medical image management system 16 also manages an image diagnostic report created based on a medical image.

  The image inspection apparatus 17 is an apparatus for generating medical image data on a patient. The image inspection apparatus 17 is, for example, an X-ray diagnostic apparatus, an X-ray CT (Computed Tomography) apparatus, an ultrasonic diagnostic apparatus, an MRI apparatus, a SPECT (Single Photon Emission Computed Tomography) apparatus, or a PET (Positron Emission computed Tomography) apparatus It is. The image inspection apparatus 17 performs an inspection based on an inspection order managed by the radiation department system 14, for example, and generates medical image data.

  Medical information management server 12 acquires predetermined information from electronic medical record system 11, medical accounting system 13, radiation department system 14, clinical examination department system 15, medical image management system 16, and image examination device 17, and acquired information Act as a database to accumulate

  Specifically, for example, the medical information management server 12 periodically sends the electronic medical record system 11, the medical accounting system 13, the radiation department system 14, the clinical examination department system 15, the medical image management system 16, and the image examination apparatus 17 to one another. to access. The medical information management server 12 may use, for example, personal information (sex, height, weight, contraindication information, age, address, used transportation when visiting hospital, and economic situation (medical expenses not paid) from the accessed system and device, for example, And the like) and patient medical information (such as disease name, symptom description etc., nursing record, medical history, medicine history, test results, diagnostic imaging report etc.). The medical information management server 12 stores the acquired patient information and patient medical information in a built-in storage circuit. At this time, the medical information management server 12 associates and stores, for example, the acquired patient information and patient medical information on a patient-by-patient basis.

  The investigational drug / unapproved drug information management server 20 plays a role of a database that accumulates information on clinical trials and information on unapproved drugs. The information on the clinical trial is collected from the information on the clinical trial protocol 31, the clinical trial recruitment information 41, the investigational drug information 42 and the like.

  The clinical trial protocol 31 is delivered to the Ministry of Health, Labor and Welfare to obtain approval for the clinical trial, and in performing the clinical trial, matters that the medical institution performing the clinical trial and the pharmaceutical company requesting the clinical trial must comply with. Is described. The trial protocol 31 includes, for example, the purpose of the trial, the trial subject such as disease and symptoms, selection criteria for the subject, exclusion criteria for the subject, name of the study drug, dose and administration method, administration period, side effects, The cost burden, the clinical trial schedule, and the test results in the first and second phases are described. Information on the clinical trial execution plan 31 is made public by public institutions such as the national health care institution 30 and the like.

  The clinical trial recruitment information 41 is information for recruiting subjects involved in the clinical trial. The trial recruitment information 41 includes, for example, planned usage / dose of the investigational drug, target disease name and symptom name, subject selection criteria, clinical trial purpose, clinical trial content, name of trial medical institution, and recruitment period, etc. included. The investigational drug information 42 is pharmaceutical information on the investigational drug used in the clinical trial. The clinical trial recruitment information 41 and the investigational drug information 42 are published by the pharmaceutical company 40 requesting a clinical trial.

  Information on unapproved drugs is collected from new drug approval information 32, 51, administration information 61, drug information 71 and the like. The new drug approval information 32 is information on a new drug newly approved in the country, and is disclosed by a public organization such as the national health organization 30. The new drug approval information 51 is information on a new drug newly approved overseas, and is disclosed by a public organization such as the overseas health institution 50. The new drug approval information 32, 51 includes, for example, an active ingredient name, a company name, an effect / efficacy, an approval date, and a research date. In the present embodiment, based on the new drug approval information 32, 51, for example, a drug that is approved overseas and not approved in the country is treated as an unapproved drug. Also, for example, drugs approved for a given disease but not approved for a disease other than the target disease are treated as unapproved drugs. Specifically, for example, it is a drug that has been approved for gastric cancer but not for lung cancer. The administration information 61 is information on a drug administered by the medical institution 60. The administration information 61 includes a drug name, a dose and an administration method, a medical facility name, an administration period, and the like. The drug information 71 is published by the overseas pharmaceutical company 70. The drug information 71 includes pharmaceutical information on an unapproved drug according to the present embodiment.

  The investigational drug / unapproved drug information management server 20 accesses the domestic health institution 30, the pharmaceutical company 40, the foreign health institution 50, and the medical institution 60. The investigational drug / unapproved drug information management server 20, for example, basic drug information on a drug basis for the investigation drug and the unapproved drug (composition, disease, symptom, contraindication, usage, etc.) Read clinical trial recruitment information (target criteria, name of clinical trial performing medical institution, recruitment period, presence / frequency of visit to hospital, cost sharing / total amount, etc.), administration information of unapproved drugs (medical care facilities, drug costs, etc.). The investigational drug / unapproved drug information management server 20 stores the read information. The investigational drug / unapproved drug information management server 20 transmits the stored information in response to the request. The investigational drug / unapproved drug information management server 20 may transmit a notification signal indicating that the information has been updated, when new information is accumulated.

  The electronic medical chart system 11 shown in FIG. 1 includes a processing server 111 and a terminal device 112. The processing server 111 and the terminal device 112 are connected so as to be capable of data communication via, for example, an in-hospital network. Although FIG. 1 shows an example in which one processing server 111 and one terminal device 112 are provided in the electronic medical record system 11, the present invention is not limited to this. A plurality of processing servers 111 and terminal devices 112 may be provided as necessary.

  The terminal device 112 is a terminal for displaying information required by a doctor or the like and for the doctor or the like to input an instruction to the processing server 111. Specifically, for example, the terminal device 112 includes a display and an input interface. When the doctor examines the patient, the terminal device 112 reads out the information on the electronic medical chart from the processing server 111, and displays the electronic medical chart based on the read out information on the display. In addition, when the doctor examines the patient, the terminal device 112 reads out proposal information on the investigational drug and the non-approved drug selected as a target to be suggested to the patient from the processing server 111, and displays the readout proposal information on the display. . The doctor refers to the electronic medical chart displayed on the terminal device 112 and examines the patient. The doctor uses the input interface of the terminal device 112, inputs findings and the like to the electronic medical chart based on the diagnosis result, and inputs an update instruction of the electronic medical chart. The information related to the updated electronic medical record is transmitted to the processing server 111 and stored in the processing server 111. The doctor also uses the input interface of the terminal device 112 to input order information and the like from the electronic medical record.

  The processing server 111 is an example of a processing device, and is a server that manages information related to electronic medical records, proposal information related to investigational drugs and unapproved drugs, and the like. The processing server 111 outputs necessary information to the terminal device 112 in response to an input from a doctor via the terminal device 112. Further, in response to the update instruction input from the terminal device 112, the processing server 111 adds the information added by the doctor to the information regarding the electronic medical record.

  FIG. 2 is a block diagram showing an example of a functional configuration of the processing server 111 shown in FIG. The processing server 111 illustrated in FIG. 2 includes a processing circuit 1111, a communication interface 1112, and a storage circuit 1113. The processing circuit 1111, the communication interface 1112, and the storage circuit 1113 are communicably connected to one another via, for example, a bus.

  The processing circuit 1111 is a processor that functions as the center of the processing server 111. The processing circuit 1111 implements a function corresponding to the program by executing a drug proposal selection program stored in the storage circuit 1113 or the like.

  The communication interface 1112 performs data communication with the medical information management server 12, the medical accounting system 13, the radiation department system 14, the clinical examination department system 15, and the medical image management system 16 connected via the in-hospital network. . Communication with the medical information management server 12, the medical accounting system 13, the radiation department system 14, the clinical examination department system 15, and the medical image management system 16 is performed in accordance with a preset known standard.

  The storage circuit 1113 is a storage device such as a hard disk drive (HDD), a solid state drive (SSD), and an integrated circuit storage device that stores various information. Further, the storage circuit 1113 may be a drive device or the like that reads and writes various information from and to a portable storage medium such as a CD-ROM drive, a DVD drive, and a flash memory. Note that the memory circuit 1113 does not have to be necessarily realized by a single memory device. For example, the memory circuit 1113 may be realized by a plurality of memory devices.

  The memory circuit 1113 stores a drug proposal selection program and the like according to the present embodiment. In addition, the storage circuit 1113 stores information related to the electronic medical record. In addition, the storage circuit 1113 stores proposal information on an investigational drug and an unapproved drug, which is selected by the processing circuit 1111 executing the drug proposal selection program.

  The processing server 111 may have an input interface. The input interface is realized by, for example, a mouse, a keyboard, and a touch panel to which an instruction is input by touching the operation surface. The input interface converts an input instruction from the operator into an electrical signal, and outputs the electrical signal to the processing circuit 1111. The input interface is not limited to one having physical operation parts such as a mouse and a keyboard. For example, a circuit that receives an electrical signal corresponding to an instruction input from an external input device provided separately from the processing server 111 and outputs the electrical signal to the processing circuit 1111 is also included in the example of the input interface.

  Also, the processing server 111 may have an output interface. The output interface is realized by, for example, a display device and a printing device. As a display apparatus, arbitrary displays, such as a CRT display, a liquid crystal display, an organic electroluminescent display, a LED display, and a plasma display, can be utilized suitably, for example. The display device displays image data of a display target. The printing device is, for example, a printer. The printing device prints image data on a print target on a predetermined sheet. The output interface is not limited to one having a display device and physical output components such as a printing device. For example, a circuit for transmitting image data to an external output device provided separately from the processing server 111 is also included in the example of the output interface.

  The processing circuit 1111 shown in FIG. 2 implements the function corresponding to the program by executing the medicine proposal selection program stored in the storage circuit 1113. For example, the processing circuit 1111 implements a drug extraction function 1111a, a compatibility determination function 1111b, a proposal information generation function 1111c, a proposal function 1111d, and an introduction information generation function 1111e by executing a drug proposal selection program. In the present embodiment, although a case where the drug extraction function 1111a, the compatibility determination function 1111b, the proposal information generation function 1111c, the proposal function 1111d, and the introduction information generation function 1111e are realized by a single processor will be described. It is not limited. For example, a plurality of independent processors are combined to form a processing circuit, and each processor executes a drug proposal selection program, whereby the drug extraction function 1111a, the conformity determination function 1111b, the proposal information creation function 1111c, the proposal function 1111d, and the introduction The information creation function 1111 e may be realized.

  The drug extraction function 1111 a is a function of extracting an investigational drug and / or an unapproved drug suitable for a patient whose information is stored in the medical information management server 12 from the investigational drug / unapproved drug information management server 20. Specifically, for example, the processing circuit 1111 executes the medicine extraction function 1111a at a preset timing. When the drug extraction function 1111a is executed, the processing circuit 1111 accesses the medical information management server 12, associates it with a predetermined patient, and is stored in the medical information management server 12. For example, the disease name and / or symptom name read out. The processing circuit 1111 may, for example, use the investigation drug / unapproved drug information management server 20 to display a list of investigational drugs that are expected to be effective for the read-out patient's disease name and / or symptom name and / or unapproved drug. Extract.

  The timing when the processing circuit 1111 executes the drug extraction function 1111 includes, for example, a preset time, a preset cycle, and the like, but is not limited thereto. Further, the processing circuit 1111 may execute the drug extraction function 1111a when receiving the notification signal indicating that the information has been updated, which is transmitted from the investigational drug / unapproved drug information management server 20.

  The compatibility determination function 1111b is a function to determine whether the investigational drug extracted by the drug extraction function 1111a and / or an unapproved drug conforms to the condition and progress of the patient. Specifically, for example, when the medicine list is extracted by the medicine extraction function 1111a, the processing circuit 1111 executes the matching judgment function 1111b. When the conformity determination function 1111 b is executed, the processing circuit 1111 performs the physical condition conformity determination and the social condition conformity determination on each of the medicines included in the medicine list.

  In the physical condition conformity determination, the processing circuit 1111 controls the investigation drug / non-approved drug information management server 20 for the investigation drug and / or the non-approved drug for which the patient's physical information stored in the medical information management server 12 is extracted. It is determined whether the various requirements stored in are satisfied. In the present embodiment, the patient's physical information includes age, sex, height, weight, contraindication information, and the like.

  Further, in the social condition conformity determination, the processing circuit 1111 performs investigational drug / unapproved drug information on the investigational drug and / or the unapproved drug from which the social information of the patient stored in the medical information management server 12 is extracted. It is determined whether the various requirements stored in the management server 20 are satisfied. In the present embodiment, the patient's social information includes an address, a visiting hospital transportation, and an economic situation.

  The processing circuit 1111 selects an investigational drug determined to be compatible with the patient in the physical condition conformity determination and the social condition conformity determination and / or an unapproved drug as a target to be proposed to the patient.

  The proposal information creation function 1111c is a function of creating proposal information based on the selected investigational drug and / or non-approved drug. Specifically, for example, when the investigational drug and / or the non-approved drug is selected, the processing circuit 1111 executes the proposal information generation function 1111c. When the proposal information creation function 1111c is executed, the processing circuit 1111 reads out detailed information on the selected investigational drug and / or non-approved drug from the investigational drug / non-approved drug information management server 20, and based on the read information, the proposed information Create The processing circuit 1111 stores the created proposal information in the memory circuit 1113.

  The proposed function 1111d is a function for proposing, to the doctor, referral of the selected investigation drug and / or non-approved drug to the patient at the start of examination of the patient. Specifically, for example, the processing circuit 1111 executes the proposal function 1111d when notified of the start of the examination of the patient from the doctor via the terminal device 112. When the proposed function 1111d is executed, the processing circuit 1111 transmits, to the terminal device 112, proposed information on the selected investigational drug and / or the unapproved drug.

  The introductory information creation function 1111 e is a function of creating introductory information including the presence or absence of introduction and the reason for not introducing. Specifically, for example, the processing circuit 1111 executes the introduction information creation function 1111e when the presence or absence of introduction of a drug is input from the doctor via the terminal device 112. When the introduction information creation function 1111e is executed, the processing circuit 1111 includes the presence or absence of introduction and the reason for not introducing based on whether the investigational drug and / or the non-approved medicine included in the proposal information is introduced to the patient. Create introductory information. The processing circuit 1111 transmits the created introduction information to the medical information management server 12. The medical information management server 12 stores the introduction information as introduction history information. The introduction history information includes, for example, presence or absence of introduction to a predetermined patient, introduction date or non-introduction date, non-introduction reason, and the like for each medicine. Further, the processing circuit 1111 transmits the introduction information to the investigational drug / non-approved drug information management server 20 after deleting and anonymizing the information that can specify the patient from the created introduction information. The investigational drug / unapproved drug information management server 20 stores the introduction information as introduction history information.

  Next, the operation when the processing server 111 configured as described above proposes an investigational drug and / or an unapproved drug to a doctor will be described in detail.

  FIG. 3 is a flowchart showing an example of an operation when the processing circuit 1111 of the processing server 111 shown in FIG. 2 creates proposal information.

  First, the processing circuit 1111 reads out the drug proposal selection program from the storage circuit 1113, for example, at a predetermined time of night, and executes the read drug proposal selection program. By the execution of the drug proposal selection program, the drug extraction function 1111a is first executed. When the drug extraction function 1111a is executed, the processing circuit 1111 accesses the medical information management server 12, and selects one patient A out of a plurality of patients examined during the day, for example. This selection may be made in accordance with the order of examination, the order of IDs, etc. Also, it may be selected from patients who have been examined in the past as well as during the day. The processing circuit 1111 reads, for example, the disease name stored in the medical information management server 12 in association with the selected patient A (step S31). If the disease name is not diagnosed, the symptom name may be read out.

  The processing circuit 1111 accesses the investigational drug / unapproved drug information management server 20, and the unapproved drug whose disease name read from the medical information management server 12 is included in the effect / effect is the investigation drug / unapproved drug information management server 20 Extract from The processing circuit 1111 also extracts, from the investigational drug / non-approved drug information management server 20, an investigational drug whose disease name read from the medical information management server 12 is included in the clinical trial target (step S32).

  When the processing circuit 1111 extracts the medicine list including the investigational drug and / or the unapproved medicine from the investigational drug / unapproved medicine information management server 20, the processing circuit 1111 executes the compatibility determination function 1111b (step S33). When the conformity determination function 1111 b is executed, the processing circuit 1111 performs the physical condition conformity determination (step S 34) and the social condition conformity determination (step S 35) for all the drugs included in the drug list. In the following description, for example, in the case where one investigation drug and one non-approved drug are extracted in step S32, first, a determination on the conformity to the investigation drug is made, and then a determination on the non-approved drug is made Will be described by way of example.

  FIG. 4 is a flowchart showing an example of the subroutine of the physical condition fit determination shown in FIG. First, the processing circuit 1111 accesses the investigational drug / non-approved drug information management server 20, and carries out trial recruitment information on the investigation drug listed in the drug list, for example, information on selection criteria of the subject and the test The information on the exclusion criteria of the person is read out (step S41).

  The processing circuit 1111 accesses the medical information management server 12, and from the personal information stored in association with the patient A, physical information such as sex, height, weight, age, contraindication information, etc. From (step S42).

  The processing circuit 1111 determines whether the physical information of the patient A read out from the medical information management server 12 satisfies the selection criteria of the subject read out from the investigational drug / non-approved drug information management server 20 (step S43). When the physical information of the patient A satisfies the selection criteria (Yes in step S43), the processing circuit 1111 reads the physical information of the patient A read from the medical information management server 12 from the investigational drug / non-approved drug information management server 20 It is determined whether there is any violation of the subject exclusion criteria (step S44). If the physical information of the patient A does not satisfy the selection criteria (No in step S43), the processing circuit 1111 determines that the investigational drug is incompatible with the patient A (step S45), and the subroutine for determining physical condition conformity End.

  In step S44, when the physical information of the patient A does not contradict the exclusion criteria (Yes in step S44), the processing circuit 1111 accesses the medical information management server 12, and the medical history from the patient medical information about the patient A (Medical history), various test values (liver function, kidney function, etc.) and the like are read out (step S46). If the physical information of the patient A violates the exclusion criteria (No in step S44), the processing circuit 1111 determines that the investigational drug is incompatible with the patient A (step S45).

  The processing circuit 1111 determines whether the medical history and various test values read out from the medical information management server 12 in step S46 satisfy the selection criteria of the subject read out from the investigational drug / non-approved drug information management server 20. Is determined (step S47). If the medical history of the patient A and the various test values satisfy the selection criteria (Yes in step S47), the processing circuit 1111 causes the medical history and the various test values read from the medical information management server 12 to be investigation drug / unapproved It is determined whether there is any conflict with the exclusion criteria for the subject read out from the medicine information management server 20 (step S48). If the medical history of the patient A and various test values do not satisfy the selection criteria (No in step S47), the processing circuit 1111 determines that the investigational drug is incompatible with the patient A (step S45).

  In step S48, if the medical history of patient A and various test values do not violate the exclusion criteria (Yes in step S48), the processing circuit 1111 determines that the investigational drug conforms to the physical condition of patient A and is physically compatible. End the judgment subroutine. If the medical history of the patient A and various test values conflict with the exclusion criteria (No in step S48), the processing circuit 1111 determines that the investigational drug is incompatible with the patient A (step S45).

  Returning to the explanation of FIG. 3, when the processing circuit 1111 determines that the investigational drug conforms to the patient A in the physical condition adaptation determination shown in step S34, it executes a social condition adaptation determination (step S35). On the other hand, when the processing circuit 1111 determines that the investigational drug is incompatible with the patient A in the physical condition matching determination shown in step S34, it sets the next drug included in the drug list, an unapproved drug in this description ( Step S36) The process for determining the suitability of the non-approved drug set through the determination shown in step S37 is performed.

  FIG. 5 is a flowchart showing an example of the subroutine of the social condition conformance determination shown in FIG. First, the processing circuit 1111 accesses the investigational drug / unapproved drug information management server 20, and the name of the clinical trial medical institution where the clinical trial using the investigation drug listed in the drug list is conducted is the investigation drug / unapproved drug It reads from the information management server 20 (step S51).

  The processing circuit 1111 accesses the medical information management server 12, and reads social information such as an address and a traffic agency used at the time of visiting from the medical information management server 12 from the personal information stored in association with the patient A. (Step S52). The processing circuit 1111 determines whether the social information of the patient A read from the medical information management server 12 conforms to social conditions (step S53). Specifically, the processing circuit 1111 determines that the distance between the address of the patient A read from the medical information management server 12 and the trial site read from the investigational drug / non-approved drug information management server 20 is an allowable distance. It is determined whether or not it is contained. The allowable distance is mainly defined in advance for each transportation system used. The allowable distance for the patient A is calculated on the basis of the visiting transportation system read out from the medical information management server 12.

  If the social information conforms to the social conditions, that is, if the distance between the patient A's address and the trial site is within the allowable distance (Yes in step S53), the processing circuit 1111 will Ends the subroutine of the social condition matching judgment as matching with the social information of the patient A. If the social information does not conform to the social conditions, that is, if the distance between the patient A's address and the trial site is not within the permissible distance (No in step S53), the processing circuit 1111 will It is determined that the medicine is unsuitable for the patient A (step S54), and the subroutine of the physical condition conformity determination is ended.

  Returning to the explanation of FIG. 3, the processing circuit 1111 refers to the introduction history information stored in the medical information management server 12 when determining that the investigational drug conforms to the patient A in the social condition conformance determination shown in step S35. It is determined whether or not there has been no result of this investigational drug being unintroduced to patient A (step S38). On the other hand, when it is determined that the investigational drug is incompatible with patient A in the social condition conformity determination shown in step S35, the processing circuit 1111 sets the next drug included in the drug list, an unapproved drug in this description ( Step S36) The process for determining the suitability of the non-approved drug set through the determination shown in step S37 is performed.

  In step S38, when there is no record that this study drug has not been introduced to patient A (Yes in step S38), the processing circuit 1111 selects this study drug and the next drug included in the medicine list, this explanation In the next step, the compliance judgment process is performed for unapproved drugs. If there is a record that this study drug has not been introduced to patient A (No in step S38), the processing circuit 1111 sets the next drug listed in the drug list, an unapproved drug in this explanation ( Step S36) The process for determining the suitability of the non-approved drug set through the determination shown in step S37 is performed.

  When the compatibility determination process for the investigational drug listed in the drug list is completed, the processing circuit 1111 executes the subroutine of the physical condition suitability determination for the non-approved drug listed in the drug list (step S34).

  First, the processing circuit 1111 accesses the investigational drug / non-approved drug information management server 20, and reads out usage information and non-continence information and the like for the non-approved drug listed in the drug list (step S41). The processing circuit 1111 accesses the medical information management server 12, and from the personal information stored in association with the patient A, physical information such as sex, height, weight, age, contraindication information, etc. From (step S42).

  The processing circuit 1111 determines whether the physical information of the patient A read from the medical information management server 12 satisfies the condition based on the usage information read from the investigational drug / non-approved drug information management server 20 (step S43). ). When the physical information of the patient A satisfies the condition based on the usage information (Yes in step S43), the processing circuit 1111 causes the physical information of the patient A read from the medical information management server 12 to be an investigational drug / non-approved drug information management server It is determined whether the condition based on the contraindication information read out from 20 is violated (step S44). If the physical information of the patient A does not satisfy the condition based on the usage information (No in step S43), the processing circuit 1111 determines that the unapproved drug is incompatible with the patient A (step S45), and the physical condition is met. End the judgment subroutine.

  In step S44, when the physical information of the patient A does not contradict the condition based on the contraindication information (Yes in step S44), the processing circuit 1111 accesses the medical information management server 12, and from the patient medical information about the patient A , Medical history, and various inspection values etc. (step S46). If the physical information of the patient A conflicts with the condition based on the contraindication information (No in step S44), the processing circuit 1111 determines that the investigational drug is incompatible with the patient A (step S45).

  The processing circuit 1111 determines whether the medical history read out from the medical information management server 12 in step S46 and various test values satisfy the conditions based on the usage information read out from the investigational drug / non-approved drug information management server 20. It determines (step S47). When the medical history of the patient A and the various test values satisfy the conditions based on the usage information (Yes in step S47), the processing circuit 1111 causes the medical history and the various test values read from the medical information management server 12 to be the investigational drug. It is determined whether or not the condition based on the contraindication information read out from the unapproved medicine information management server 20 is violated (step S48). If the medical history of the patient A and various test values do not satisfy the condition based on the usage information (No in step S47), the processing circuit 1111 determines that the non-approved drug is incompatible with the patient A (step S45). ).

  In step S48, when the medical history of the patient A and the various test values do not contradict the conditions based on the contraindication information (Yes in step S48), the processing circuit 1111 matches the unapproved drug with the physical condition of the patient A End the subroutine for determining the body condition conformity. If the medical history of the patient A and the various test values conflict with the conditions based on the contraindication information (No in step S48), the processing circuit 1111 determines that the non-approved drug is incompatible with the patient A ( Step S45).

  Returning to the description of FIG. 3, when it is determined that the unapproved drug conforms to the patient A in the physical condition conformance determination shown in step S34, the processing circuit 1111 executes a social condition conformance determination (step S35). On the other hand, when the processing circuit 1111 determines that the unapproved drug is incompatible with the patient A in the determination of the body condition conformity shown in step S34, the processing circuit 1111 sets the next drug included in the drug list (step S36). If the next drug is not present in the drug list (No in step S37), the matching determination on the patient A is ended (step S39).

  The processing circuit 1111 accesses the investigational drug / non-approved drug information management server 20 in the social condition conformity determination shown in FIG. 5 and handles the medical treatment facilities to which the non-approved drug listed in the drug list has been administered. Are read out from the investigational drug / unapproved drug information management server 20 (step S51).

  The processing circuit 1111 accesses the medical information management server 12 and uses the personal information stored in association with the patient A to manage social information, such as an address, a transportation used for visiting hospital, and an economic situation etc. It reads from the server 12 (step S52). The processing circuit 1111 determines whether the social information of the patient A read from the medical information management server 12 conforms to social conditions (step S53). Specifically, the processing circuit 1111 determines that the distance between the address of the patient A read from the medical information management server 12 and the medical treatment facility read from the investigational drug / non-approved drug information management server 20 is an allowable distance. It is determined whether or not it is contained. In addition, the processing circuit 1111 determines whether or not there is an unpaid record of medical expenses in the economic situation read from the medical information management server 12. Patients who have unpaid medical expenses are likely to be unable to bear the heavy burden of unapproved drugs.

  When the social information conforms to social conditions, that is, the distance between the patient A's address and the medical facility to be treated is within the allowable distance, and the financial situation does not have unpaid medical expenses (Yes in step S53), the processing circuit 1111 ends the social condition conformity determination subroutine on the assumption that the investigational drug matches the social information of the patient A. If the social information does not fit the social conditions, ie the distance between the patient A's address and the medical care facility is not within the permissible distance, or the financial situation has not been paid for medical expenses In the case (No in step S53), the processing circuit 1111 determines that the non-approved drug is incompatible with the patient A (step S54), and ends the subroutine of the physical condition conformity determination.

  Returning to the explanation of FIG. 3, the processing circuit 1111 refers to the introduction history information stored in the medical information management server 12 when it determines that the unapproved drug conforms to the patient A in the social condition conformance determination shown in step S35. Then, it is determined whether there is no record of this unapproved drug being unintroduced to patient A (step S38). On the other hand, when it is determined that the unapproved drug is incompatible with patient A in the social condition compliance determination shown in step S35, processing circuit 1111 ends the compatibility determination for patient A through steps S36 and S37 (step S39). ).

  In step S38, when there is no record that the unapproved drug has not been introduced to the patient A (Yes in step S38), the processing circuit 1111 selects the unapproved drug. Then, when there is no next drug included in the drug list, the processing circuit 1111 ends the determination on the suitability of the patient A (step S39).

  The processing circuit 1111 executes the proposal information generation function 1111c when the matching determination processing is completed and the investigational drug and / or the non-approved drug are selected in this processing. When the proposal information creation function 1111 c is executed, the processing circuit 1111 reads out detailed information on the selected investigational drug and / or non-approved drug from the investigational drug / unapproved drug information management server 20. Detailed information on the investigational drug includes, for example, information on investigational drug name, investigational drug generic name, investigational subject, side effects, results of previous phase test, name of investigational medical institution, dosage / dosage, mechanism of action, etc. Is included. Detailed information on unapproved drugs includes, for example, information on active ingredient name, company name, efficacy / effect, approved country, and medical facilities treated. The processing circuit 1111 creates proposal information based on the read information (step S310).

  At this time, the processing circuit 1111 may divide the type of information into a plurality of types in the proposal information. For example, the processing circuit 1111 creates summary information representing a summary of proposal information and detailed information representing detailed information of a drug included in the proposal information. For example, for the investigational drug, the processing circuit 1111 outlines the name of the investigational drug, the subject of the investigation, the phase of the investigation, the name of the investigational medical institution, etc. I assume. In addition, for example, for the investigational drug, the processing circuit 1111 includes the general name of the investigational drug, the action mechanism, the test result in the previous phase, the side effect, etc., and for the unapproved drug, the active ingredient name, manufacturing company name, And approve country etc. as detailed information. The proposal information created is stored in the storage circuit 1113.

  The processing circuit 1111 performs the processing shown in FIGS. 3 to 5 on the patient stored in the medical information management server 12. The processing circuit 1111 may perform the process on all the patients stored in the medical information management server 12 or perform the process on a predetermined one of the patients stored in the medical information management server 12. May be

  The processing circuit 1111 proposes the created proposal information to the doctor, for example, as follows. A doctor accesses the processing server 111 via the terminal device 112 when examining a patient. The doctor obtains from the processing server 111 a patient list in which the patient's name, patient ID, etc. are aligned. The doctor specifies the patient to be examined next from the patient list, and inputs a request signal of information on the electronic medical record. When the processing circuit 1111 of the processing server 111 receives the request signal, the processing circuit 1111 reads out the information on the electronic medical chart for the designated patient from the storage circuit 1113 or the medical information management server 12.

  When the processing circuit 1111 receives the request signal, the processing circuit 1111 executes the proposal function 1111d. When the proposing function 1111 d is executed, the processing circuit 1111 determines whether the proposing information about the designated patient is stored in the storage circuit 1113. When the proposal information about the designated patient is stored in the storage circuit 1113, the processing circuit 1111 includes the proposal information in the information on the electronic medical record. The processing circuit 1111 transmits the electronic medical record information including the proposal information to the terminal device 112.

  When the terminal device 112 receives the electronic medical record information from the processing server 111, the terminal device 112 displays, on the medical care platform screen, patient information, medical care information, and information indicating that the proposal information exists. FIG. 6 is a schematic view showing a display example of the terminal device 112. As shown in FIG. According to FIG. 6, when the proposal information exists, the notification button F21 for notifying that the proposal information exists blinks on the patient information display unit F2 in the medical care platform screen F1 of the electronic medical record system. This enables the doctor to recognize that new information has been proposed.

  For example, when the display of the proposal information is requested by pressing the notification button F21, the terminal device 112 displays the summary information included in the proposal information. Further, the terminal device 112 displays summary information and also displays an icon for accepting whether to introduce the proposed medicine to the patient. In addition, the terminal device 112 displays an icon for receiving a request for detailed information of the proposed medicine.

  FIG. 7 is a schematic view showing an example of summary information on a study drug displayed by the terminal device 112. As shown in FIG. According to FIG. 7, on the summary display screen F3, the name of the investigational drug, which is outline information of the investigational drug: "AAAA drug", the subject of the clinical trial: "XX disease", the phase of the clinical trial: "during phase 3 clinical trial" Bearer: "Company cost burden", and name of trial medical institution performing the trial: "Please go to ○ hospital △ hospital 要 hospital". Also, on the summary display screen F3, an icon F31 for displaying detailed information of AAAA drug, an icon F32 pressed when introducing the AAAA drug to the patient, and an icon F33 pressed when not introducing the AAAA drug to the patient Is displayed.

  For example, when the display of the detailed information of the medicine is requested by pressing the icon F31, the terminal device 112 displays the detailed information included in the proposal information. FIG. 8 is a schematic view showing an example of detailed information on a study drug displayed on the terminal device 112. As shown in FIG. According to FIG. 8, the detailed display screen F4 displays the general name which is the detailed information of the investigational drug, the action mechanism, the results of the first phase and the second phase test, and the information on the side effect. The physician refers to the summary information and the detailed information to determine whether to introduce the proposed drug, eg, investigational drug: AAAA drug, to the patient.

  When introducing the proposed medicine to the patient, the doctor presses an icon F32 displayed on the summary display screen F3. When the icon F32 is pressed, the terminal device 112 transmits, to the processing server 111, a notification signal notifying that a displayed drug, for example, an investigational drug: AAAA drug, has been introduced to the patient.

  When the processing circuit 1111 of the processing server 111 receives the notification signal from the terminal device 112, the processing circuit 1111 executes the introduction information creation function 1111e. When the introduction information creation function 1111 e is executed, the processing circuit 1111 creates introduction information indicating that the AAAA drug was introduced to the patient on the date when the patient was examined. The processing circuit 1111 transmits the created introduction information to the medical information management server 12 and the investigational drug / non-approved drug information management server 20.

  If the proposed medicine is not introduced to the patient, the doctor presses an icon F33 displayed on the summary display screen F3. When the icon F33 is pressed, the terminal device 112 displays an input form for inputting the reason why the drug was not introduced. The reason for not introducing a drug may be to select at least one of a plurality of reasons provided in advance, or to input an arbitrary character. FIG. 9 is a schematic view showing an example of a form F5 displayed on the terminal device 112 for inputting a reason for non-introduction. In Fig. 9, the investigational drug: The reason for not introducing the AAAA drug is "patient cost burden is large", "investigation is impossible due to remote location", "I can not agree to participate in clinical trial", and "treatment with prescription drug" You can choose from In FIG. 9, “investigation impossible due to remote location” is selected among these. Note that examples of selectable reasons are not limited to these.

  When the reason why the drug was not introduced is input, the terminal device 112 notifies that the drug being displayed, for example, investigational drug: AAAA drug was not introduced to the patient, and the reason why it was not introduced. A signal is sent to the processing server 111.

  When the processing circuit 1111 of the processing server 111 receives the notification signal from the terminal device 112, the processing circuit 1111 executes the introduction information creation function 1111e. When the introduction information creation function 1111 e is executed, the processing circuit 1111 creates introduction information indicating that the AAAA drug was not introduced to the patient for the notified reason on the date when the patient was examined. The processing circuit 1111 transmits the created introduction information to the medical information management server 12. The medical information management server 12 stores the introduction information as introduction history information.

  The processing circuit 1111 deletes the information that can specify the patient from the created introduction information and anonymizes it. The processing circuit 1111 transmits the anonymized introduction information to the investigational drug / non-approved drug information management server 20. The investigational drug / unapproved drug information management server 20 stores the introduction information as introduction history information.

  The anonymized introduction history information stored in the investigational drug / unapproved drug information management server 20 can be used, for example, for new drug development in a pharmaceutical company. FIG. 10 is a diagram showing an example of utilization of introduction history information. In FIG. 10, the positional relationship between the trial site, public transportation, and the residence of the patient is schematically represented. The figures for each area represent the number of patients who have not been referred to and the number of patients who have not been referred to due to the location of the trial site. According to FIG. 10, it is possible to grasp the regional uneven distribution of the clinical trial needs of the drug and to help improve the clinical trial plan.

  FIG. 11 is a diagram showing another example of utilization of introduction history information. FIG. 11 plots in two dimensions the correlation between the economic situation of cases not introduced due to economic circumstances and the cost burden scale of unapproved drugs and investigational drugs. According to FIG. 11, it becomes possible to formulate an appropriate selling price plan for the drug.

  As described above, in the present embodiment, the processing circuit 1111 of the processing server 111 stores the patient's personal information and patient medical information stored in the medical information management server 12 and the investigational drug / non-approved drug information management server 20. Based on the information on the investigation drug and the non-approved drug stored, the investigation drug and / or the non-approved drug suitable for the patient are selected. The terminal device 112 connected to the processing circuit 1111 displays the selected investigational drug and / or the non-approved drug when the doctor examines the patient. As a result, the attending physician can automatically propose information on investigational drugs and unapproved drugs that match the patient, simply by inputting daily medical care to the processing server 111 of the electronic medical record system 11.

  Therefore, according to the hospital information system according to the present embodiment, the doctor can provide the patient with new treatment information suitable for the patient at the time of medical treatment. In addition, patients will have the opportunity to receive the most up-to-date treatment, as they will be informed by the attending physician of the latest information on new drugs.

  Further, the processing circuit 1111 of the processing server 111 transmits the information on the selected investigational drug and / or the non-approved drug to the terminal device 112 together with the data on the electronic medical chart when the examination for the patient is started. Then, the terminal device 112 displays an electronic medical chart for the patient and displays on the electronic medical chart that the selected investigational drug and / or the non-approved drug exist. This enables the doctor to examine the patient while recognizing the presence of the selected investigational drug and / or the unapproved drug from the start of the examination.

  In addition, the processing circuit 1111 of the processing server 111 determines whether the physical information of the patient satisfies the physical condition for administering the extracted investigational drug and / or the non-approved drug. In addition, the processing circuit 1111 determines whether the social information of the patient satisfies the social condition for continuing the administration of the extracted investigational drug and / or the non-approved drug. This makes it possible to select investigational drugs that can be continuously administered to patients and / or unapproved drugs.

  In addition, the processing circuit 1111 of the processing server 111 transmits to the medical information management server 12 whether or not the selected investigational drug and / or the non-approved drug is actually introduced. Thereby, the medical information management server 12 can accumulate information on the investigational drug introduced to the patient and / or the unapproved drug.

  Further, the processing circuit 1111 of the processing server 111 determines whether or not there is a history in which the selected investigational drug and / or the non-approved drug have been unintroduced in the past by referring to the medical information management server 12 Do. Then, the processing circuit 1111 excludes a drug having a history of being unintroduced to the same patient from being referred to this patient. In this way, the introductory information becomes feedback for the subsequent introductions. That is, as the electronic medical record system 11 is used, more appropriate information can be obtained.

  In addition, the processing circuit 1111 of the processing server 111 transmits to the medical information management server 12 whether or not the selected investigational drug and / or the non-approved drug were actually introduced, and if not introduced, the reason for non-introduction. I am sending it. As a result, the medical information management server 12 can analyze the reason why the investigational drug and / or the unapproved drug has not been introduced.

  In addition, the processing circuit 1111 of the processing server 111 anonymizes the investigation drug and / or the unapproved drug if the investigation drug and / or the unapproved drug were actually introduced or not, It is made to transmit to the non-approved drug information management server 20. Thereby, the investigational drug / unapproved drug information management server 20 can analyze the reason why the investigation drug and / or the unapproved drug is not introduced. That is, it is possible to contribute to the efficient development of a clinical trial plan in a pharmaceutical company or the like.

  Further, in the present embodiment, the medical information management server 12 periodically sends the electronic medical record system 11, the medical accounting system 13, the radiation department system 14, the clinical examination department system 15, the medical image management system 16, and the image examination apparatus 17 to one another. Access and obtain personal information about the patient and patient medical information from the accessed system and device. Then, the medical information management server 12 links and stores the acquired information for each patient. As a result, the medical information management server 12 accumulates various information about the patient.

  Further, in the present embodiment, the investigational drug / unapproved drug information management server 20 accesses the domestic health institution 30, the pharmaceutical company 40, the foreign health institution 50, and the medical institution 60, and from the accessed institution and company. Obtain information on investigational drugs and unapproved drugs. Then, the investigational drug / unapproved drug information management server 20 stores the obtained information in association with each drug. As a result, the investigational drug / unapproved drug information management server 20 accumulates various information on the trial and the unapproved drug.

  In the above embodiment, the case where the investigational drug / unapproved drug information management server 20 is provided outside the hospital information system 10 has been described as an example. However, it is not limited to this. The investigational drug / unapproved drug information management server 20 may be included in the hospital information system 10a as shown in FIG.

  The word “processor” used in the description of the embodiment is, for example, a central processing unit (CPU), a graphics processing unit (GPU), or an application specific integrated circuit (ASIC)), a programmable logic device It means circuits such as (for example, Simple Programmable Logic Device (SPLD), Complex Programmable Logic Device (CPLD), and Field Programmable Gate Array (FPGA)). The processor implements the function by reading out and executing the drug proposal selection program stored in the memory circuit 1113. Note that instead of storing the drug proposal selection program in the memory circuit 1113, the drug proposal selection program may be directly incorporated in the circuit of the processor. In this case, the processor realizes the function by reading out and executing a drug proposal selection program incorporated in the circuit. Note that the processor described in the above embodiment is not limited to being configured as a single circuit, and a plurality of independent circuits may be combined to be configured as one processor to realize its function.

  Although the embodiments of the present invention have been described, this embodiment is presented as an example and is not intended to limit the scope of the invention. This embodiment can be implemented in other various forms, and various omissions, replacements, and changes can be made without departing from the scope of the invention. These embodiments and modifications thereof are included in the invention described in the claims and the equivalents thereof as well as included in the scope and the gist of the invention.

  10, 10a ... hospital information system, 11 ... electronic medical record system, 111 ... processing server, 1111 ... processing circuit, 1111a ... drug extraction function, 1111b ... conformity judging function, 1111c ... proposal information creation function, 1111d ... proposal function, 1111e ... Introduction information creation function, 1112 ... communication interface, 1113 ... memory circuit, 112 ... terminal device, 12 ... medical information management server, 13 ... medical accounting system, 14 ... radiation department system, 15 ... clinical examination department system, 16 ... medical image Management system, 17 ... image inspection equipment, 20 ... unapproved drug information management server, 30 ... domestic health institution, 31 ... trial implementation plan, 32 ... new drug approval information, 40 ... pharmaceutical company, 41 ... trial recruitment information, 42 ... Investigational drug information, 50: Overseas health institutions, 51: New drug approval information, 60: Medical institutions, 61: Administration information , 70 ... overseas pharmaceutical companies, 71 ... drug information.

Claims (9)

Patient-suitable investigational drug and / or non-approved based on personal information and patient medical information about the patient stored in the first database and information on investigational drug and non-approved drug stored in the second database A processor for selecting a drug,
Connected to the processor by an in-hospital network, and when a doctor examines a patient, the investigational drug and / or the non-approved drug selected by the processor is displayed to the doctor for referral to the patient A hospital information system comprising a terminal device.   When the terminal device starts the medical examination, the terminal device indicates that the selected investigational drug and / or the non-approved drug is present, and requests display of the selected investigation drug and / or the non-approved drug. The hospital information system according to claim 1, wherein the selected investigational drug and / or the non-approved drug is displayed according to. The processing unit
An extraction unit for extracting an investigation drug and / or an unapproved drug corresponding to a disease name or a symptom name of a patient from the investigation drug and the unapproved drug stored in the second database;
By determining whether the patient meets the conditions for administering the extracted investigational drug and / or the non-approved drug, and whether the patient meets the conditions for continuing the administration, The hospital information system according to claim 1 or 2, further comprising: a determination unit that selects an investigational drug and / or an unapproved drug suitable for the patient. The processing apparatus receives an introduction information creation unit that receives whether or not the selected investigational drug and / or unapproved drug has been actually introduced to the patient, and transmits the presence or absence of the introduction as introduction information to the first database. In addition,
The determination unit refers to the first database, and selects an investigation drug and / or an unapproved drug without a history of having not been referred to as an investigation drug and / or an unapproved drug compatible with the patient The hospital information system according to Item 3.   When the referral information creation unit does not introduce the selected investigational drug and / or the non-approved drug to the patient, it accepts the reason and transmits the presence or absence of the referral and the reason to the first database. The hospital information system according to claim 4.   The hospital information system according to claim 5, wherein the introduction information creation unit anonymizes the presence or absence of the introduction and the reason and transmits the anonymized information to the second database. Further comprising the first database;
The hospital information system according to any one of claims 1 to 6, wherein the first database collects the personal information and the patient medical information from a plurality of systems in a hospital. Further comprising the second database;
The hospital information system according to any one of claims 1 to 7, wherein the second database collects information on the investigational drug and the unapproved drug from a pharmaceutical company, a domestic health institution, and an overseas health institution. Patient-suitable investigational drug and / or non-approved based on personal information and patient medical information about the patient stored in the first database and information on investigational drug and non-approved drug stored in the second database The process of selecting a drug,
A drug proposal selection program which causes a processor to execute a process of displaying the selected investigational drug and / or non-approved drug to the doctor for referral to the patient when the doctor examines the patient.