JP2018529346A - 免疫細胞、特に単球の同定のためのエピジェネティックマーカーとしてのｐａｒｋ２ - Google Patents

免疫細胞、特に単球の同定のためのエピジェネティックマーカーとしてのｐａｒｋ２ Download PDF

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JP2018529346A
JP2018529346A JP2018515530A JP2018515530A JP2018529346A JP 2018529346 A JP2018529346 A JP 2018529346A JP 2018515530 A JP2018515530 A JP 2018515530A JP 2018515530 A JP2018515530 A JP 2018515530A JP 2018529346 A JP2018529346 A JP 2018529346A
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monocytes
seq
cells
cpg
region
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JP2018529346A5 (enExample
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オレク，スフェン
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エピオンティス ゲーエムベーハー
エピオンティス ゲーエムベーハー
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Publication of JP2018529346A publication Critical patent/JP2018529346A/ja
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6881—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/154—Methylation markers

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Mechanical Control Devices (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2018515530A 2015-09-25 2016-09-22 免疫細胞、特に単球の同定のためのエピジェネティックマーカーとしてのｐａｒｋ２ Pending JP2018529346A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1516975.8 2015-09-25
GBGB1516975.8A GB201516975D0 (en) 2015-09-25 2015-09-25 PARK2 as epigenetic marker for the identification of immune cells, in particular monocytes
PCT/EP2016/072594 WO2017050925A1 (en) 2015-09-25 2016-09-22 Park2 as epigenetic marker for the identification of immune cells, in particular monocytes

Publications (2)

Publication Number Publication Date
JP2018529346A true JP2018529346A (ja) 2018-10-11
JP2018529346A5 JP2018529346A5 (enExample) 2019-10-31

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JP2018515530A Pending JP2018529346A (ja) 2015-09-25 2016-09-22 免疫細胞、特に単球の同定のためのエピジェネティックマーカーとしてのｐａｒｋ２

Country Status (7)

Country Link
US (1) US11761041B2 (enExample)
EP (1) EP3353319B1 (enExample)
JP (1) JP2018529346A (enExample)
CN (2) CN108026590B (enExample)
CA (1) CA2999614C (enExample)
GB (1) GB201516975D0 (enExample)
WO (1) WO2017050925A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022191293A1 (ja) * 2021-03-12 2022-09-15 エーザイ・アール・アンド・ディー・マネジメント株式会社 全単球及びｃｄ１６陽性単球の割合の測定方法

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102017125013B4 (de) * 2017-10-25 2019-10-17 Epiontis Gmbh MCC als epigenetischer Marker zur Identifizierung von Immunzellen, insbesondere basophiler Granulozyten
DE102017125150B4 (de) * 2017-10-26 2019-10-10 Epiontis Gmbh Endosialin (CD248) als epigenetischer Marker zur Identifizierung von Immunzellen, insbesondere naïver CD8+ T-Zellen
DE102017125335B4 (de) * 2017-10-27 2019-10-17 Epiontis Gmbh Amplikon-Region als epigenetischer Marker zur Identifizierung von Immunzellen, insbesondere nicht-klassischer Monozyten
HK1256212A2 (zh) * 2018-12-27 2019-09-13 汪恩光 拉动式的换挡传动系统及食物料理机

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014170497A2 (en) * 2013-04-19 2014-10-23 Epiontis Gmbh Method for identifying the quantitative cellular composition in a biological sample

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1826279T3 (da) * 2006-02-28 2011-09-05 Charite Universitaetsmedizin Detektering og kvalitetskontrol af regulatoriske t-celler vha. DNA-metyleringsanalyse af FoxP3--genet
CA2671270A1 (en) * 2006-12-29 2008-07-17 Asuragen, Inc. Mir-16 regulated genes and pathways as targets for therapeutic intervention
EP2248913B1 (en) * 2009-04-28 2016-10-05 Epiontis GmbH GNLY as epigenetic marker for the identification of CD56-expressing natural killer cells
EP2558594A2 (en) * 2010-04-16 2013-02-20 Koninklijke Philips Electronics N.V. Methods for the analysis of breast cancer disorders
US20130129668A1 (en) * 2011-09-01 2013-05-23 The Regents Of The University Of California Diagnosis and treatment of arthritis using epigenetics
WO2013067451A2 (en) * 2011-11-04 2013-05-10 Population Diagnostics Inc. Methods and compositions for diagnosing, prognosing, and treating neurological conditions

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014170497A2 (en) * 2013-04-19 2014-10-23 Epiontis Gmbh Method for identifying the quantitative cellular composition in a biological sample

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022191293A1 (ja) * 2021-03-12 2022-09-15 エーザイ・アール・アンド・ディー・マネジメント株式会社 全単球及びｃｄ１６陽性単球の割合の測定方法

Also Published As

Publication number Publication date
GB201516975D0 (en) 2015-11-11
WO2017050925A1 (en) 2017-03-30
CA2999614C (en) 2023-02-28
US11761041B2 (en) 2023-09-19
CN211582764U (zh) 2020-09-29
CN108026590B (zh) 2023-10-31
HK1257582A1 (en) 2019-10-25
CA2999614A1 (en) 2017-03-30
EP3353319B1 (en) 2020-10-21
EP3353319A1 (en) 2018-08-01
US20180216184A1 (en) 2018-08-02
CN108026590A (zh) 2018-05-11

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