JP2018514576A5 - - Google Patents
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- Publication number
- JP2018514576A5 JP2018514576A5 JP2017557405A JP2017557405A JP2018514576A5 JP 2018514576 A5 JP2018514576 A5 JP 2018514576A5 JP 2017557405 A JP2017557405 A JP 2017557405A JP 2017557405 A JP2017557405 A JP 2017557405A JP 2018514576 A5 JP2018514576 A5 JP 2018514576A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- combination according
- cd16a
- combination
- multifunctional
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15166303.6 | 2015-05-04 | ||
| EP15166303.6A EP3091031A1 (en) | 2015-05-04 | 2015-05-04 | Combination of a bispecific antibody with an immune modulating molecule for the treatment of a tumor |
| EP16152650.4 | 2016-01-25 | ||
| EP16152650 | 2016-01-25 | ||
| PCT/EP2016/060113 WO2016177846A1 (en) | 2015-05-04 | 2016-05-04 | Combination of a cd30xcd16 antibody with a pd-1 antagonist for therapy |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018514576A JP2018514576A (ja) | 2018-06-07 |
| JP2018514576A5 true JP2018514576A5 (https=) | 2019-06-13 |
| JP6609784B2 JP6609784B2 (ja) | 2019-11-27 |
Family
ID=56026814
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017557405A Active JP6609784B2 (ja) | 2015-05-04 | 2016-05-04 | 治療のためのｃｄ３０×ｃｄ１６抗体とｐｄ−１アンタゴニストとの組み合わせ |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US11167029B2 (https=) |
| EP (1) | EP3292153B1 (https=) |
| JP (1) | JP6609784B2 (https=) |
| CN (1) | CN107847587B (https=) |
| AU (1) | AU2016257334B2 (https=) |
| BR (1) | BR112017023579A2 (https=) |
| CA (2) | CA3219372A1 (https=) |
| CY (1) | CY1122283T1 (https=) |
| DK (1) | DK3292153T3 (https=) |
| ES (1) | ES2754557T3 (https=) |
| HR (1) | HRP20191933T1 (https=) |
| HU (1) | HUE045866T2 (https=) |
| LT (1) | LT3292153T (https=) |
| PL (1) | PL3292153T3 (https=) |
| PT (1) | PT3292153T (https=) |
| RS (1) | RS59489B1 (https=) |
| RU (1) | RU2761352C2 (https=) |
| SI (1) | SI3292153T1 (https=) |
| SM (1) | SMT201900598T1 (https=) |
| WO (1) | WO2016177846A1 (https=) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2018226526B2 (en) | 2017-02-28 | 2025-03-13 | Affimed Gmbh | Combination of an anti-CD16A antibody with a cytokine |
| WO2018158349A1 (en) | 2017-02-28 | 2018-09-07 | Affimed Gmbh | Tandem diabody for cd16a-directed nk-cell engagement |
| CN109706164A (zh) * | 2017-10-26 | 2019-05-03 | 深圳新诺微环生物科技有限公司 | 微环dna表达连接人和猴cd20与效应细胞抗原的桥接分子及其应用 |
| CN109706163A (zh) * | 2017-10-26 | 2019-05-03 | 深圳新诺微环生物科技有限公司 | 微环dna表达连接人与动物靶细胞与效应细胞的桥接分子及其应用 |
| BR112020018492A2 (pt) | 2018-03-14 | 2020-12-29 | Affimed Gmbh | Proteína de ligação ao antígeno egfr/cd16 biespecífica |
| CA3095373A1 (en) * | 2018-04-13 | 2019-10-17 | Affimed Gmbh | Nk cell engaging antibody fusion constructs |
| HRP20240821T1 (hr) * | 2018-08-27 | 2024-09-27 | Affimed Gmbh | Stanice nk čuvane zamrzavanjem, koje su prethodno ubačene uz protutijelni konstrukt |
| CN109402168A (zh) * | 2018-10-30 | 2019-03-01 | 深圳新诺微环生物科技有限公司 | 微环dna表达连接her2阳性细胞与效应细胞的桥接分子及其应用 |
| JP2022536684A (ja) * | 2019-06-11 | 2022-08-18 | マイエロイド・セラピューティクス，インコーポレーテッド | マクロファージ特異的エンゲージャー組成物およびその使用方法 |
| AU2020414409A1 (en) * | 2019-12-27 | 2022-06-16 | Affimed Gmbh | Method for the production of bispecific FcyRIIl x CD30 antibody construct |
| JP2024503933A (ja) * | 2021-01-27 | 2024-01-29 | イノベント バイオロジクス（スーチョウ）カンパニー，リミティド | Ｃｄ１６ａに対する単一ドメイン抗体およびその使用 |
| WO2023274183A1 (zh) | 2021-06-29 | 2023-01-05 | 江苏先声药业有限公司 | Cd16抗体及其应用 |
| EP4413039A1 (en) | 2021-10-08 | 2024-08-14 | Genmab A/S | Antibodies binding to cd30 and cd3 |
| CN118613271A (zh) * | 2021-11-04 | 2024-09-06 | 埃迪瓦生物治疗公司 | 用nk细胞和多特异性接合子治疗癌症 |
| WO2023080895A1 (en) * | 2021-11-04 | 2023-05-11 | Artiva Biotherapeutics, Inc. | Treatment of cancer with nk cells and multispecific engagers |
| CN116059348A (zh) * | 2022-09-16 | 2023-05-05 | 四川大学华西医院 | 基于nkg2d的细胞接合器分子在清除衰老细胞中的应用 |
| WO2024114676A1 (zh) | 2022-11-29 | 2024-06-06 | 江苏恒瑞医药股份有限公司 | Cldn18.2/4-1bb结合蛋白及其医药用途 |
| AR132290A1 (es) | 2023-04-05 | 2025-06-11 | Genmab As | Composiciones farmacéuticas que comprenden anticuerpos que se unen a cd30 y cd3 |
| CN117442721B (zh) * | 2023-12-20 | 2024-03-15 | 苏州艾凯利元生物科技有限公司 | 一种包括nk细胞和nk细胞接合器分子的组合物 |
| CN118791616A (zh) * | 2024-09-14 | 2024-10-18 | 苏州为度生物技术有限公司天津分公司 | 一种抗人cd16工程抗体及应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0510790D0 (en) * | 2005-05-26 | 2005-06-29 | Syngenta Crop Protection Ag | Anti-CD16 binding molecules |
| CA2611861C (en) * | 2005-06-08 | 2017-11-28 | The Brigham And Women's Hospital, Inc. | Methods and compositions for the treatment of persistent infections |
| US9682143B2 (en) * | 2012-08-14 | 2017-06-20 | Ibc Pharmaceuticals, Inc. | Combination therapy for inducing immune response to disease |
| EP3183269A2 (en) * | 2014-08-22 | 2017-06-28 | Bristol-Myers Squibb Company | Treatment of cancer using a combination of an anti-pd-1 antibody and an anti-cd137 antibody |
-
2016
- 2016-05-04 LT LT16723968T patent/LT3292153T/lt unknown
- 2016-05-04 PT PT167239680T patent/PT3292153T/pt unknown
- 2016-05-04 JP JP2017557405A patent/JP6609784B2/ja active Active
- 2016-05-04 WO PCT/EP2016/060113 patent/WO2016177846A1/en not_active Ceased
- 2016-05-04 BR BR112017023579A patent/BR112017023579A2/pt active Search and Examination
- 2016-05-04 DK DK16723968.0T patent/DK3292153T3/da active
- 2016-05-04 RU RU2017137251A patent/RU2761352C2/ru active
- 2016-05-04 HR HRP20191933TT patent/HRP20191933T1/hr unknown
- 2016-05-04 SM SM20190598T patent/SMT201900598T1/it unknown
- 2016-05-04 RS RS20191372A patent/RS59489B1/sr unknown
- 2016-05-04 CA CA3219372A patent/CA3219372A1/en active Pending
- 2016-05-04 CN CN201680026411.5A patent/CN107847587B/zh active Active
- 2016-05-04 EP EP16723968.0A patent/EP3292153B1/en active Active
- 2016-05-04 HU HUE16723968A patent/HUE045866T2/hu unknown
- 2016-05-04 CA CA2983706A patent/CA2983706C/en active Active
- 2016-05-04 SI SI201630463T patent/SI3292153T1/sl unknown
- 2016-05-04 PL PL16723968T patent/PL3292153T3/pl unknown
- 2016-05-04 AU AU2016257334A patent/AU2016257334B2/en active Active
- 2016-05-04 ES ES16723968T patent/ES2754557T3/es active Active
-
2017
- 2017-10-19 US US15/788,177 patent/US11167029B2/en active Active
-
2019
- 2019-10-25 CY CY20191101115T patent/CY1122283T1/el unknown
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