JP2018512973A - 自動注射器の駆動機構 - Google Patents
自動注射器の駆動機構 Download PDFInfo
- Publication number
- JP2018512973A JP2018512973A JP2017555544A JP2017555544A JP2018512973A JP 2018512973 A JP2018512973 A JP 2018512973A JP 2017555544 A JP2017555544 A JP 2017555544A JP 2017555544 A JP2017555544 A JP 2017555544A JP 2018512973 A JP2018512973 A JP 2018512973A
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- JP
- Japan
- Prior art keywords
- rotor
- actuator
- plunger rod
- drive mechanism
- drug delivery
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000007246 mechanism Effects 0.000 title claims abstract description 28
- 238000012377 drug delivery Methods 0.000 claims abstract description 63
- 239000012190 activator Substances 0.000 claims abstract description 24
- 239000003814 drug Substances 0.000 description 23
- 229940079593 drug Drugs 0.000 description 20
- 230000001681 protective effect Effects 0.000 description 5
- 239000000243 solution Substances 0.000 description 5
- 238000002347 injection Methods 0.000 description 4
- 239000007924 injection Substances 0.000 description 4
- 230000035515 penetration Effects 0.000 description 4
- 239000006199 nebulizer Substances 0.000 description 2
- 230000002093 peripheral effect Effects 0.000 description 2
- 230000004913 activation Effects 0.000 description 1
- 239000006071 cream Substances 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 230000037452 priming Effects 0.000 description 1
- 230000001960 triggered effect Effects 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
- A61M5/2033—Spring-loaded one-shot injectors with or without automatic needle insertion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/3148—Means for causing or aiding aspiration or plunger retraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
- A61M2005/2006—Having specific accessories
- A61M2005/2013—Having specific accessories triggering of discharging means by contact of injector with patient body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
- A61M2005/31588—Constructional features or modes of drive mechanisms for piston rods electrically driven
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
- A61M5/321—Means for protection against accidental injuries by used needles
- A61M5/3243—Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel
- A61M5/326—Fully automatic sleeve extension, i.e. in which triggering of the sleeve does not require a deliberate action by the user
Landscapes
- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
Description
本発明は、薬剤送達装置の駆動機構に関し、特に、高度な自動機能を備えた薬剤送達装置に関する。
看護師や医師ではないユーザによって使用されたり取り扱われたりする、すなわち、患者自身によって取り扱われる用途に設計された薬剤送達装置が絶えず開発されている。本発明の出願人は、薬の混合、プライミング、貫入、注入・充填、および/または薬剤送達部材ガードの伸長を含む高度な自動機能を示す薬剤送達装置を大量に開発してきた。
本発明の目的は、従来の駆動機構の欠点を改善することである。この目的は、独立請求項の特徴を有する、薬剤送達装置の駆動機構によって達成される。好適な実施形態は、独立請求項に記載されている。
以下の説明において、薬剤送達装置という表現が使用される。これに関して、薬剤送達装置は、たとえば、注射針付きのまたは注射針なしの注射装置、パウダー、噴霧式、ガスなどのあらゆる種類の吸入器、マウスピースまたはノーズピースを有するネブライザ、錠剤の形態の薬剤のディスペンサ、点眼用ディスペンサ、クリーム/ジェルディスペンサなど、特定の投与量の薬剤をユーザに送達可能な複数の装置を含み得る。薬剤送達装置は、使い捨てタイプであっても再利用可能タイプであってもよく、特別な形状の特別な薬に適するように用意された薬剤容器が備えられてもよい。
Claims (10)
- 薬剤送達装置に使用される駆動機構であって、
プランジャーロッド(68)と、
前記プランジャーロッドに対して操作可能に構成された駆動用ばね(72)と、
伸長状態の前記駆動用ばね(72)を装填した前記プランジャーロッド(68)を保持するために前記プランジャーロッド(68)と解放可能に係合された保持部材(60)を備えるアクチュエータ(52)と、
前記アクチュエータ(52)に操作可能に接続され、前記アクチュエータ(52)に対して可動であり、前記保持部材を前記プランジャーロッドと係合した状態に保持するために、前記保持部材と相互に作用し合うように構成された回転子(38)と、
前記回転子(38)に操作可能に接続されるアクティベータ(30)とを備え、前記回転子(38)を回転させ、その後、前記保持部材(60)が前記プランジャーロッド(68)から解放されるように、前記回転子(38)を前記アクチュエータ(52)に対して線形に転置するように前記アクティベータ(30)が構成されることを特徴とする、駆動機構。 - 前記アクチュエータ(52)は、前記回転子(38)が回転されたときに前記回転子(38)が載る案内面(58)とともに構成されている、請求項1に記載の駆動機構。
- 前記回転子(38)は、前記回転子(38)を回転させた後に前記回転子(38)を前記アクチュエータ(52)に対して線形に転置することを可能にするための、前記案内面(58)を差し込むことができる切欠き(48)とともに構成されている、請求項2に記載の駆動機構。
- 前記回転子(38)は、長手方向に対して傾斜した第1案内隆起部(42i)を備え、前記アクティベータ(30)は、前記回転子(38)を回転させるために、前記第1案内隆起部(42i)に対して作用する、請求項1〜3のいずれかに記載の駆動機構。
- 前記回転子(38)は、前記第1案内隆起部(42i)と相互に連結された第2案内隆起部(42r)を備え、前記第2案内隆起部(42r)は、前記長手方向(L)を概ね横断しており、前記アクティベータ(30)は、前記回転子(38)を動かすために、前記第2案内隆起部(42i)に対して作用する、請求項4に記載の駆動機構。
- 前記回転子(38)は、前記アクチュエータ(52)上の第2方向付け要素(71)と相互に作用し合うために操作可能に構成され、前記回転子(38)に前記アクチュエータ(52)が組み合される際の方向付けの助けを提供するための第1方向付け要素(51)を備える、請求項1〜5のいずれかに記載の駆動機構。
- 前記第1方向付け要素(51)は、縦溝を備え、前記第2方向付け要素(71)は、前記縦溝に嵌め込まれるように構成された凸部を備える、請求項6に記載の駆動機構。
- 前記回転子(38)を前記アクチュエータ(52)に取り付けるときに前記凸部(71)が嵌め込まれることになる停止凹部(53)を前記回転子(38)上にさらに備える、請求項7に記載の駆動機構。
- 前記アクティベータ(30)は、薬剤送達部材ガードである、請求項1〜8のいずれかに記載の駆動機構。
- 請求項1〜9のいずれかに記載の駆動機構を備える、薬剤送達装置。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE1550496 | 2015-04-24 | ||
SE1550496-2 | 2015-04-24 | ||
PCT/EP2016/057342 WO2016169756A1 (en) | 2015-04-24 | 2016-04-04 | Drive mechanism for an autoinjector |
Publications (3)
Publication Number | Publication Date |
---|---|
JP2018512973A true JP2018512973A (ja) | 2018-05-24 |
JP2018512973A5 JP2018512973A5 (ja) | 2018-07-05 |
JP6567687B2 JP6567687B2 (ja) | 2019-08-28 |
Family
ID=55802341
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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JP2017555544A Active JP6567687B2 (ja) | 2015-04-24 | 2016-04-04 | 自動注射器の駆動機構 |
Country Status (7)
Country | Link |
---|---|
US (1) | US10881797B2 (ja) |
EP (1) | EP3285832A1 (ja) |
JP (1) | JP6567687B2 (ja) |
KR (1) | KR102016829B1 (ja) |
CN (1) | CN107635603B (ja) |
TW (1) | TWI630936B (ja) |
WO (1) | WO2016169756A1 (ja) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2399635A1 (en) | 2010-06-28 | 2011-12-28 | Sanofi-Aventis Deutschland GmbH | Auto-injector |
MX2022003700A (es) * | 2019-09-30 | 2022-04-26 | Amgen Inc | Dispositivo de administracion de farmacos. |
WO2021110344A1 (en) * | 2019-12-05 | 2021-06-10 | Shl Medical Ag | Feedback mechanisms |
US20230270942A1 (en) * | 2020-08-07 | 2023-08-31 | Sanofi | Arrangement for a drug delivery device |
WO2023104512A1 (en) * | 2021-12-07 | 2023-06-15 | Shl Medical Ag | A subassembly of a medicament delivery device |
WO2023151952A1 (en) * | 2022-02-08 | 2023-08-17 | Shl Medical Ag | A subassembly of a medicament delivery device |
WO2024008491A1 (en) * | 2022-07-07 | 2024-01-11 | Shl Medical Ag | A sub-assembly of a medicament delivery device |
WO2024022643A1 (en) * | 2022-07-26 | 2024-02-01 | Shl Medical Ag | Cap for medicament delivery device |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2013016832A1 (de) * | 2011-08-04 | 2013-02-07 | Tecpharma Licensing Ag | Sicherheitseinrichtung für injektionsvorrichtungen |
JP2013526904A (ja) * | 2010-03-31 | 2013-06-27 | エス・ホー・エル・グループ・アクチボラゲット | フィードバック信号伝達手段を備えた薬剤送達装置 |
JP2018513751A (ja) * | 2015-04-24 | 2018-05-31 | ケアベイ・ヨーロッパ・リミテッドCarebay Europe Limited | 薬剤送達装置のサブアセンブリおよび薬剤送達装置 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2414402B (en) * | 2004-05-28 | 2009-04-22 | Cilag Ag Int | Injection device |
US8740854B2 (en) * | 2007-06-04 | 2014-06-03 | Becton, Dickinson And Company | Stopper and plunger rod for a pre-filled syringe |
CA2804156A1 (en) * | 2010-07-02 | 2012-01-05 | Itero Biopharmaceuticals, Inc. | Preservative-free follicle stimulating hormone solution delivery device |
GB201020472D0 (en) * | 2010-12-02 | 2011-01-19 | Oval Medical Technologies Ltd | A drive assembly for an autoinjector |
TWI471151B (zh) * | 2011-01-11 | 2015-02-01 | Shl Group Ab | 藥物輸送裝置 |
WO2012138285A1 (en) * | 2011-04-05 | 2012-10-11 | Shl Group Ab | Medicament delivery device comprising a locking mechanism having a lever |
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2016
- 2016-04-04 EP EP16717582.7A patent/EP3285832A1/en active Pending
- 2016-04-04 KR KR1020177033851A patent/KR102016829B1/ko active IP Right Grant
- 2016-04-04 WO PCT/EP2016/057342 patent/WO2016169756A1/en active Application Filing
- 2016-04-04 US US15/568,816 patent/US10881797B2/en active Active
- 2016-04-04 CN CN201680028458.5A patent/CN107635603B/zh active Active
- 2016-04-04 JP JP2017555544A patent/JP6567687B2/ja active Active
- 2016-04-12 TW TW105111382A patent/TWI630936B/zh active
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2013526904A (ja) * | 2010-03-31 | 2013-06-27 | エス・ホー・エル・グループ・アクチボラゲット | フィードバック信号伝達手段を備えた薬剤送達装置 |
WO2013016832A1 (de) * | 2011-08-04 | 2013-02-07 | Tecpharma Licensing Ag | Sicherheitseinrichtung für injektionsvorrichtungen |
JP2018513751A (ja) * | 2015-04-24 | 2018-05-31 | ケアベイ・ヨーロッパ・リミテッドCarebay Europe Limited | 薬剤送達装置のサブアセンブリおよび薬剤送達装置 |
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Publication number | Publication date |
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US20180104415A1 (en) | 2018-04-19 |
JP6567687B2 (ja) | 2019-08-28 |
KR20170139636A (ko) | 2017-12-19 |
EP3285832A1 (en) | 2018-02-28 |
KR102016829B1 (ko) | 2019-08-30 |
TWI630936B (zh) | 2018-08-01 |
CN107635603B (zh) | 2020-09-01 |
TW201707739A (zh) | 2017-03-01 |
WO2016169756A1 (en) | 2016-10-27 |
US10881797B2 (en) | 2021-01-05 |
CN107635603A (zh) | 2018-01-26 |
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