JP2018511339A5 - - Google Patents

Info

Publication number

JP2018511339A5

JP2018511339A5 JP2017553984A JP2017553984A JP2018511339A5 JP 2018511339 A5 JP2018511339 A5 JP 2018511339A5 JP 2017553984 A JP2017553984 A JP 2017553984A JP 2017553984 A JP2017553984 A JP 2017553984A JP 2018511339 A5 JP2018511339 A5 JP 2018511339A5

Authority

JP

Japan

Prior art keywords

irobeti

gene

mitochondrial

rna

lee

Prior art date

2016-04-15

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Links

• Espacenet
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• 108020005196 Mitochondrial DNA Proteins 0.000 claims 43
• 108091032973 (ribonucleotides)n+m Proteins 0.000 claims 38
• 108090000623 proteins and genes Proteins 0.000 claims 33
• 238000000034 method Methods 0.000 claims 23
• 238000011002 quantification Methods 0.000 claims 22
• 208000005384 Pneumocystis Pneumonia Diseases 0.000 claims 16
• 206010073755 Pneumocystis jirovecii pneumonia Diseases 0.000 claims 16
• 239000002299 complementary DNA Substances 0.000 claims 16
• 230000002438 mitochondrial effect Effects 0.000 claims 16
• 201000000317 pneumocystosis Diseases 0.000 claims 16
• 239000000523 sample Substances 0.000 claims 14
• 101150001086 COB gene Proteins 0.000 claims 10
• 101150053771 MT-CYB gene Proteins 0.000 claims 10
• 101150006264 ctb-1 gene Proteins 0.000 claims 10
• 101150088166 mt:Cyt-b gene Proteins 0.000 claims 10
• 108020004418 ribosomal RNA Proteins 0.000 claims 10
• 108091093088 Amplicon Proteins 0.000 claims 6
• 241000142787 Pneumocystis jirovecii Species 0.000 claims 6
• 230000000295 complement effect Effects 0.000 claims 6
• 239000003814 drug Substances 0.000 claims 5
• 229940079593 drug Drugs 0.000 claims 5
• FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 4
• 108091034117 Oligonucleotide Proteins 0.000 claims 4
• 238000012408 PCR amplification Methods 0.000 claims 4
• 238000010839 reverse transcription Methods 0.000 claims 4
• 102100034343 Integrase Human genes 0.000 claims 3
• 108091028043 Nucleic acid sequence Proteins 0.000 claims 3
• 108010092799 RNA-directed DNA polymerase Proteins 0.000 claims 3
• 239000013060 biological fluid Substances 0.000 claims 3
• 238000000338 in vitro Methods 0.000 claims 3
• 239000000463 material Substances 0.000 claims 3
• 239000002773 nucleotide Substances 0.000 claims 3
• 125000003729 nucleotide group Chemical group 0.000 claims 3
• 238000004364 calculation method Methods 0.000 claims 2
• 239000000969 carrier Substances 0.000 claims 2
• 238000003753 real-time PCR Methods 0.000 claims 2
• 102100025287 Cytochrome b Human genes 0.000 claims 1
• 108020004414 DNA Proteins 0.000 claims 1
• 235000010469 Glycine max Nutrition 0.000 claims 1
• 244000068988 Glycine max Species 0.000 claims 1
• 101000858267 Homo sapiens Cytochrome b Proteins 0.000 claims 1
• 238000002123 RNA extraction Methods 0.000 claims 1
• 238000004590 computer program Methods 0.000 claims 1
• 238000000605 extraction Methods 0.000 claims 1
• 210000003470 mitochondria Anatomy 0.000 claims 1
• 108020004707 nucleic acids Proteins 0.000 claims 1
• 102000039446 nucleic acids Human genes 0.000 claims 1
• 150000007523 nucleic acids Chemical class 0.000 claims 1
• 238000000746 purification Methods 0.000 claims 1