JP2018508323A - 血行障害測定装置及びその方法 - Google Patents
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- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
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- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/02007—Evaluating blood vessel condition, e.g. elasticity, compliance
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- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
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- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/021—Measuring pressure in heart or blood vessels
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- A61B5/021—Measuring pressure in heart or blood vessels
- A61B5/02108—Measuring pressure in heart or blood vessels from analysis of pulse wave characteristics
- A61B5/02125—Measuring pressure in heart or blood vessels from analysis of pulse wave characteristics of pulse wave propagation time
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- A61B5/024—Detecting, measuring or recording pulse rate or heart rate
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- A61B5/346—Analysis of electrocardiograms
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Abstract
Description
110:測定部
120:検出部
130:演算部
140:診断部
Eff:EKG R peak-femoral pulse wave foot間のPulse transit timeの平均
EBf:EKG R peak-brachial pulse wave foot間のPulse transit timeの平均
Erf:EKG R peak-radial pulse wave foot間のPulse transit timeの平均
CFf:carotid-femoral pulse wave foot間のPulse transit timeの平均
CBf:carotid-brachial pulse wave foot間のPulse transit timeの平均
CRf:carotid-radial pulse wave foot間のPulse transit timeの平均
EFp:EKG R peak-femoral pulse wave peak間のPulse transit timeの平均
EBp:EKG R peak-brachial pulse wave peak間のPulse transit timeの平均
ERp:EKG R peak-radial pulse wave peak間のPulse transit timeの平均
ECp:EKG R peak-carotid pulse wave peak間のPulse transit timeの平均
(A1 * A2)+(A1 * A3)、(A1 * A2)+(A1 * A4)、(A1 * A2)+(A2 * A3)、(A1 * A2)+(A2 * A4)、(A1 * A2)+(A3 * A4)、(A1 * A3)+(A1 * A4)、(A1 * A3)+(A2 * A3)、(A1 * A3) +(A2 * A4)、(A1 * A3)+(A3 * A4)、(A1 * A4)+(A2 * A3)、(A1 * A4)+(A2 * A4)、(A1 * A4)+( A3 * A4)、(A2 * A3)+(A2 * A4)、(A2 * A3)+(A3 * A4)、(A2 * A4)+(A3 * A4)のうちのいずれか一つの値を持つことができる。
正常群:4.36超過
境界領域:4.12〜4.36
疾患群:4.12未満
脳血管疾患:2.17超過
境界領域:1.89〜2.17
心血管疾患:1.89未満
Claims (10)
- 脈波伝達時間を用いた血行障害測定装置において、測定対象者の脈波と心電図を測定する測定部と、前記測定された心電図の最大(peak)値点と脈波の最大(peak)値点と最小(foot)値点の時間情報を検出する検出部、
前記検出された心電図の最大(peak)値点と脈波の最大(peak)値点と最小(foot)値点の時間情報を用いて、脈波伝達時間の平均値を計算し、これを用いて血行障害の判別指標を演算する演算部、
そして前記演算された血行障害の判別指標を用いて、血行障害を診断する診断部
とを含む血行障害測定装置。 - 前記測定部は、頸動脈、上腕、橈骨と大腿部のうちの少なくともいずれか一つの部位の脈波を測定する請求項1に記載の血行障害測定装置。
- 前記演算部は、心電図の最大(peak)値点と脈波の最小(foot)値点の間の脈波伝達時間の平均を用いて、血管疾患かどうかを判別する疾患群/正常群の判別指標を演算する請求項2に記載の血行障害測定装置。
- 前記演算部は、EFfをEBfで割った値(EFf/EBf)、EFfをERfで割った値(EFf/ERf)、CFfをCBfで割った値(CFf/CBf)、及びCFfをCRfで割った値(CFf/CRf)のうちの少なくとも一つを用いて前記疾患群/正常群の判別指標を演算し、前記EFfは心電図の最大値点と大腿部から測定された脈波の最小値点との間の脈波伝達時間の平均を表すパラメータであり、前記EBfは心電図の最大値点と上腕から測定された脈波の最小値点との間の脈波伝達時間の平均を表すパラメータであり、前記ERfは心電図の最大値点と橈骨から測定された脈波の最小値点との間の脈波伝達時間の平均を表すパラメータであり、CFfは頸動脈と大腿部から測定された脈波の最小値点との間の脈波伝達時間の平均を表すパラメータであり、前記CBfは頸動脈と上腕から測定された脈波の最小値点との間の脈波伝達時間の平均を表すパラメータであり、前記CRfは頸動脈と橈骨から測定された脈波の最小値点との間の脈波伝達時間の平均を示すパラメータである請求項3に記載の血行障害測定装置。
- 前記演算部は、心電図や脈波の最大(peak)値点の間の脈波伝達時間の平均を用いて、血管疾患の種類を判別する心血管疾患群/脳血管疾患群の判別指標を演算する請求項2に記載の血行障害測定装置。
- 前記演算部は、ECpをパラメータEFpで割った値(ECp/EFp)、パラメータECpをパラメータEBpで割った値(ECp/EBp)及びECpをERpで割った値(ECp/ERp)のうちの少なくとも一つを用いて、前記心血管疾患群/脳血管疾患群の判別指標を演算し、前記EFpは心電図の最大値点と大腿部から測定された脈波の最大値点との間の脈波伝達時間の平均を表すパラメータであり、前記EBpは心電図の最大値点と上腕から測定された脈波の最大値点との間の脈波伝達時間の平均を表すパラメータであり、前記ERpは心電図の最大値点と橈骨から測定された脈波の最大値点との間の脈波伝達時間の平均を表すパラメータであり、前記ECpは心電図の最大値点と頸動脈から測定された脈波の最大値点との間の脈波伝達時間の平均を示すパラメータである請求項5に記載の血行障害測定装置。
- 脈波伝達時間を用いて、血行障害を測定する方法において、測定対象者の脈波と心電図を測定するステップと、
前記測定された心電図の最大(peak)値点及び測定された脈波の最大(peak)値点と最小(foot)値点との時間情報を検出するステップと、
前記検出された最大(peak)値点と最小(foot)値点の時間情報を用いて、脈波伝達時間を計算するステップと、
前記脈波伝達時間を用いて、血行障害の判別指標を演算するステップと、
前記演算された血行障害の判別指標を用いて、血行障害を診断するステップ
とを含む血行障害測定方法。 - 前記脈波と心電図を測定するステップは、頸動脈、上腕、橈骨と大腿部のうちの少なくともいずれか一つの部位の脈波を測定する請求項7に記載の血行障害測定方法。
- 前記検出された最大(peak)値点と最小(foot)値点の時間情報を用いて、脈波伝達時間を計算し、血行障害の判別指標を演算するステップは、心電図の最大(peak )値点と脈波の最小(foot)値点の間の脈波伝達時間の平均を用いて、血管疾患かどうかを判別する疾患群/正常群の指標を演算する請求項7に記載の血行障害測定方法。
- 前記検出された最大(peak)値点と最小(foot)値点の時間情報を用いて、脈波伝達時間を計算し、血行障害の判別指標を演算するステップは、心電図や脈波の最大(peak)値点の間の脈波伝達時間の平均を用いて、血管疾患の種類を判別する心血管疾患群/脳血管疾患群の指標を演算する請求項7に記載の血行障害測定方法。
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KR10-2015-0012097 | 2015-01-26 | ||
PCT/KR2015/008859 WO2016133255A1 (ko) | 2015-01-26 | 2015-08-25 | 혈액순환장애 측정 장치 및 그 방법 |
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JPH053858A (ja) * | 1991-06-28 | 1993-01-14 | Colleen Denshi Kk | 血圧モニタ装置 |
US6331162B1 (en) * | 1999-02-01 | 2001-12-18 | Gary F. Mitchell | Pulse wave velocity measuring device |
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- 2015-08-25 AU AU2015383230A patent/AU2015383230A1/en not_active Abandoned
- 2015-08-25 EP EP15882788.1A patent/EP3251593B1/en active Active
- 2015-08-25 US US15/546,245 patent/US11083385B2/en active Active
- 2015-08-25 JP JP2017558343A patent/JP6725533B2/ja active Active
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EP3251593B1 (en) | 2022-06-29 |
CN107427245A (zh) | 2017-12-01 |
WO2016133255A1 (ko) | 2016-08-25 |
AU2015383230A1 (en) | 2017-08-31 |
KR20160092101A (ko) | 2016-08-04 |
EP3251593A4 (en) | 2018-08-22 |
KR101646439B1 (ko) | 2016-08-08 |
EP3251593A1 (en) | 2017-12-06 |
US20170367595A1 (en) | 2017-12-28 |
US11083385B2 (en) | 2021-08-10 |
JP6725533B2 (ja) | 2020-07-22 |
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