JP2018503685A5 - - Google Patents
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- JP2018503685A5 JP2018503685A5 JP2017556784A JP2017556784A JP2018503685A5 JP 2018503685 A5 JP2018503685 A5 JP 2018503685A5 JP 2017556784 A JP2017556784 A JP 2017556784A JP 2017556784 A JP2017556784 A JP 2017556784A JP 2018503685 A5 JP2018503685 A5 JP 2018503685A5
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- JP
- Japan
- Prior art keywords
- pharmaceutical composition
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- net
- inhibitor
- subject
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562105342P | 2015-01-20 | 2015-01-20 | |
| US62/105,342 | 2015-01-20 | ||
| PCT/US2016/013847 WO2016118476A1 (en) | 2015-01-20 | 2016-01-19 | Anti-net compounds for treating and preventing fibrosis and for facilitating wound healing |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2018503685A JP2018503685A (ja) | 2018-02-08 |
| JP2018503685A5 true JP2018503685A5 (enExample) | 2019-02-21 |
Family
ID=56417634
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017556784A Pending JP2018503685A (ja) | 2015-01-20 | 2016-01-19 | 線維化を処置および予防するためのならびに創傷治癒を促進するための抗net化合物 |
Country Status (5)
| Country | Link |
|---|---|
| US (3) | US11400139B2 (enExample) |
| EP (2) | EP3247386A4 (enExample) |
| JP (1) | JP2018503685A (enExample) |
| CA (1) | CA2974369A1 (enExample) |
| WO (1) | WO2016118476A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3351263A1 (en) * | 2017-01-20 | 2018-07-25 | Universitätsklinikum Hamburg-Eppendorf | Pharmaceutical preparation for treating or preventing tissue adhesion |
| AU2018318313B2 (en) | 2017-08-18 | 2025-01-23 | Neutrolis Inc. | Engineered DNase enzymes and use in therapy |
| WO2019173835A1 (en) * | 2018-03-09 | 2019-09-12 | The University Of Memphis Research Foundation | Compositions and methods for inhibiting inflammation |
| WO2020006389A1 (en) * | 2018-06-29 | 2020-01-02 | Viktor Veniaminovich Tets | Compositions for modulating gut microbiota |
| CN114341111B (zh) * | 2019-09-06 | 2024-11-29 | 阿根廷国家科学技术研究委员会 | 用于局部伤口治疗的药物组合物 |
| GB202012326D0 (en) * | 2020-08-07 | 2020-09-23 | Citryll B V | Diagnostic |
| CN113358872B (zh) * | 2021-06-03 | 2022-10-21 | 中山大学肿瘤防治中心(中山大学附属肿瘤医院、中山大学肿瘤研究所) | 用于评估肿瘤免疫治疗疗效的标志物组及系统 |
Family Cites Families (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3270960A (en) | 1964-09-11 | 1966-09-06 | Sperry Rand Corp | Fluid sensor |
| US3773919A (en) | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
| US4534899A (en) | 1981-07-20 | 1985-08-13 | Lipid Specialties, Inc. | Synthetic phospholipid compounds |
| US4426330A (en) | 1981-07-20 | 1984-01-17 | Lipid Specialties, Inc. | Synthetic phospholipid compounds |
| US4837028A (en) | 1986-12-24 | 1989-06-06 | Liposome Technology, Inc. | Liposomes with enhanced circulation time |
| US4920016A (en) | 1986-12-24 | 1990-04-24 | Linear Technology, Inc. | Liposomes with enhanced circulation time |
| US6919320B1 (en) * | 1987-10-28 | 2005-07-19 | Wellstat Therapeutics Corporation | Pharmaceutical compositions containing deoxyribonucleosides for wound healing |
| GB8824593D0 (en) | 1988-10-20 | 1988-11-23 | Royal Free Hosp School Med | Liposomes |
| DE68929551T2 (de) | 1988-12-23 | 2008-03-06 | Genentech, Inc., South San Francisco | Menschliche DNase |
| DE3903672C1 (enExample) | 1989-02-08 | 1990-02-01 | Lohmann Gmbh & Co Kg | |
| US5013556A (en) | 1989-10-20 | 1991-05-07 | Liposome Technology, Inc. | Liposomes with enhanced circulation time |
| US5225212A (en) | 1989-10-20 | 1993-07-06 | Liposome Technology, Inc. | Microreservoir liposome composition and method |
| US5356633A (en) | 1989-10-20 | 1994-10-18 | Liposome Technology, Inc. | Method of treatment of inflamed tissues |
| US5665710A (en) | 1990-04-30 | 1997-09-09 | Georgetown University | Method of making liposomal oligodeoxynucleotide compositions |
| JP3220180B2 (ja) | 1991-05-23 | 2001-10-22 | 三菱化学株式会社 | 薬剤含有タンパク質結合リポソーム |
| JP3351476B2 (ja) | 1993-01-22 | 2002-11-25 | 三菱化学株式会社 | リン脂質誘導体及びそれを含有するリポソーム |
| US5395619A (en) | 1993-03-03 | 1995-03-07 | Liposome Technology, Inc. | Lipid-polymer conjugates and liposomes |
| US6191105B1 (en) | 1993-05-10 | 2001-02-20 | Protein Delivery, Inc. | Hydrophilic and lipophilic balanced microemulsion formulations of free-form and/or conjugation-stabilized therapeutic agents such as insulin |
| CA2137297C (en) | 1993-12-06 | 2000-04-18 | Tsuyoshi Miyazaki | Reactive vesicle and functional substance-fixed vesicle |
| US5543152A (en) | 1994-06-20 | 1996-08-06 | Inex Pharmaceuticals Corporation | Sphingosomes for enhanced drug delivery |
| US5820873A (en) | 1994-09-30 | 1998-10-13 | The University Of British Columbia | Polyethylene glycol modified ceramide lipids and liposome uses thereof |
| US5756122A (en) | 1995-06-07 | 1998-05-26 | Georgetown University | Liposomally encapsulated nucleic acids having high entrapment efficiencies, method of manufacturer and use thereof for transfection of targeted cells |
| US5539878A (en) | 1995-06-16 | 1996-07-23 | Elonex Technologies, Inc. | Parallel testing of CPU cache and instruction units |
| US5858397A (en) | 1995-10-11 | 1999-01-12 | University Of British Columbia | Liposomal formulations of mitoxantrone |
| US5858401A (en) | 1996-01-22 | 1999-01-12 | Sidmak Laboratories, Inc. | Pharmaceutical composition for cyclosporines |
| JP3756313B2 (ja) | 1997-03-07 | 2006-03-15 | 武 今西 | 新規ビシクロヌクレオシド及びオリゴヌクレオチド類縁体 |
| EP1012331B1 (en) | 1997-07-01 | 2006-03-29 | Isis Pharmaceuticals, Inc. | Compositions and methods for the delivery of oligonucleotides via the alimentary canal |
| JP2002537343A (ja) | 1999-02-23 | 2002-11-05 | アイシス・ファーマシューティカルス・インコーポレーテッド | 多重粒子製剤 |
| IT1318539B1 (it) | 2000-05-26 | 2003-08-27 | Italfarmaco Spa | Composizioni farmaceutiche a rilascio prolungato per lasomministrazione parenterale di sostanze idrofile biologicamente |
| WO2003015698A2 (en) | 2001-08-13 | 2003-02-27 | University Of Pittsburgh | Application of lipid vehicles and use for drug delivery |
| JPWO2005075414A1 (ja) | 2004-02-04 | 2007-10-11 | 公立大学法人横浜市立大学 | ペプチジルアルギニンデイミナーゼ4阻害剤 |
| US20070213292A1 (en) | 2005-08-10 | 2007-09-13 | The Rockefeller University | Chemically modified oligonucleotides for use in modulating micro RNA and uses thereof |
| WO2007056389A2 (en) | 2005-11-07 | 2007-05-18 | University Of South Carolina | Synthesis and use of novel inhibitors and inactivators of protein arginine deiminases |
| US8617542B2 (en) | 2008-04-03 | 2013-12-31 | Kane Biotech Inc. | DispersinB™, 5-fluorouracil, deoxyribonuclease I and proteinase K-based antibiofilm compositions and uses thereof |
| EP2288616B1 (en) | 2008-06-16 | 2012-11-21 | Chiralix B.V. | Peptidylarginine deiminase (pad) inhibitors |
| US9642822B2 (en) * | 2011-05-27 | 2017-05-09 | Children's Medical Center Corporation | Methods for treating and preventing neutrophil-derived net toxicity and thrombosis |
| EP2775304A1 (en) * | 2013-03-07 | 2014-09-10 | Universitätsspital Basel | Methods for detecting inflammatory disorder |
| JP6327626B2 (ja) * | 2013-04-09 | 2018-05-23 | 国立大学法人 東京大学 | 白血球の細胞外トラップ形成の阻害剤 |
| GB201309180D0 (en) | 2013-05-21 | 2013-07-03 | Ucl Business Plc | Compounds and Their Uses |
| CN105358187B (zh) * | 2013-06-24 | 2018-06-22 | 登士伯Ih有限公司 | 包含胶原-vi的医疗装置 |
-
2016
- 2016-01-19 EP EP16740569.5A patent/EP3247386A4/en not_active Withdrawn
- 2016-01-19 JP JP2017556784A patent/JP2018503685A/ja active Pending
- 2016-01-19 US US15/544,618 patent/US11400139B2/en active Active
- 2016-01-19 WO PCT/US2016/013847 patent/WO2016118476A1/en not_active Ceased
- 2016-01-19 EP EP20187049.0A patent/EP3797789B1/en active Active
- 2016-01-19 CA CA2974369A patent/CA2974369A1/en not_active Abandoned
-
2022
- 2022-06-24 US US17/848,998 patent/US20230190886A1/en not_active Abandoned
-
2025
- 2025-03-26 US US19/091,081 patent/US20250242000A1/en active Pending
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