JP2018203635A - Oil-in-water type emulsion cosmetic - Google Patents

Abstract

To provide an oil-in-water type emulsion cosmetic having good skin compatibility and excellent penetration feeling to the skin by suppressing superficial feeling during application.SOLUTION: There is provided an oil-in-water type emulsion cosmetic which comprises: (A) 0.10 to 2.0 mass% of glycosyl trehalose; (B) acetylglucosamine represented by the following formula (1) or a derivative thereof; (C) a carboxyvinyl polymer and/or an alkyl-modified carboxyvinyl polymer; and (D) 3 to 20 mass% of a trivalent and/or tetravalent polyhydric alcohol, wherein the mass ratio (B)/(C) of the component (B) to the component (C) is 0.05 to 0.8. (Rrepresents H or an alkyl group having 2 to 18 carbon atoms; R, Rand Rare the same or different and represent H or an acyl group having 2 to 18 carbon atoms; the three-dimensional structure at the 1-position may be either α or β.)SELECTED DRAWING: None

Description

  The present invention relates to an oil-in-water emulsified cosmetic.

In recent years, glycosyl trehalose has been studied for its application to cosmetics because it improves the water retention function, cell activation effect, and cell protection effect of the skin, and can feel a moist but non-sticky film feeling after application ( Non-patent document 1).
For example, by using a mixture of glycosyl trehalose / hydrogenated starch degradation product and highly polymerized polyethylene glycol, a topical skin preparation has been proposed that does not cause sliminess or stickiness, gives the skin firmness, and improves skin sagging. (Patent Document 1).

Fragrance Journal Vol.31 No.11 Page.106-113

JP 2010-241743 A

  When the present inventors use a carboxyvinyl polymer or an alkyl-modified carboxyvinyl pyrimer in an oil-in-water emulsified cosmetic containing glycosyl trehalose and a trivalent or tetravalent polyhydric alcohol, a feeling of slipping occurs when applied. The problem of poor skin fit and impaired penetration into the skin was observed.

  Therefore, as a result of intensive studies, the present inventor has formulated an oil-in-water emulsified cosmetic containing a trivalent and / or a tetravalent polyhydric alcohol in glycosyl trehalose and containing a carboxyvinyl polymer or an alkyl-modified carboxyvinyl pyrmer. In addition, by containing acetylglucosamine in a specific ratio, oil-in-water emulsified makeup that suppresses the feeling of slipping at the time of application, has good skin fit, excellent skin penetration, and excellent stability over time. It was found that a fee can be obtained.

The present invention includes the following components (A) to (D):
(A) Glycosyl trehalose 0.10 to 2.0% by mass,
(B) General formula (1)

(Wherein R ¹ represents a hydrogen atom or an alkyl group having 2 to 18 carbon atoms, R ² , R ³ and R ⁴ are the same or different and represent a hydrogen atom or an acyl group having 2 to 18 carbon atoms; (The three-dimensional structure at the 1-position may be either α or β)
Acetylglucosamine or a derivative thereof represented by
(C) carboxyvinyl polymer and / or alkyl-modified carboxyvinyl polymer,
(D) 3-20 mass% of trivalent and / or tetravalent polyhydric alcohol
And the mass ratio (B) / (C) of the component (B) to the component (C) is 0.05 to 0.8.

  The oil-in-water emulsified cosmetic of the present invention suppresses the feeling of upslip at the time of application, has good skin fit, and is excellent in feeling of penetration into the skin and moist feeling. Also, the stability over time is good.

  In the glycosyl trehalose of component (A) used in the present invention, the glycosyl group directly linked to trehalose can be obtained by losing the hemiacetal hydroxyl group from the sugar molecule, regardless of whether it is a monosaccharide or a polysaccharide, a glucosyl group, fructosyl group, galactosyl Group, maltosyl group, maltotriosyl group, maltotetraosyl group and the like. The glycosyl trehalose is preferably one or more selected from glucosyl trehalose, maltosyl trehalose, maltotriosyl trehalose and maltotetraosyl trehalose, and one selected from glucosyl trehalose, maltosyl trehalose and maltotriosyl trehalose. Or 2 or more types are more preferable.

  A commercial item can be used for these, and specifically Tornere (registered trademark) (glycosyl trehalose / hydrogenated starch decomposition product mixed solution, Hayashibara Co., Ltd.) can be mentioned. Tornale® is a glycosyl trehalose containing glucosyl trehalose, maltosyl trehalose and maltotriosyl trehalose, and a hydrogenated starch degradation product containing sorbitol, maltitol, maltotriitol, maltotetritol, maltopentitol and It is an aqueous solution comprising 47% by mass of glycosyl trehalose, 27% by mass of hydrogenated starch degradation product and 26% by mass of water.

  The content of the component (A) is 0.10% by mass or more, preferably 0.15% by mass or more, and preferably 0.20% by mass in the oil-in-water emulsion cosmetic from the viewpoint of improving moist feeling and film feeling. % Or more is more preferable, 2.0 mass% or less, 1.5 mass% or less is preferable, and 1.0 mass% or less is more preferable. Moreover, content of a component (A) is 0.10-2.0 mass% in an oil-in-water type emulsion cosmetic, 0.15-1.5 mass% is preferable, 0.20-1.0 The mass% is more preferable.

  The component (B) is acetylglucosamine represented by the general formula (1) or a derivative thereof.

(Wherein R ¹ represents a hydrogen atom or an alkyl group having 2 to 18 carbon atoms, R ² , R ³ and R ⁴ are the same or different and represent a hydrogen atom or an acyl group having 2 to 18 carbon atoms; (The three-dimensional structure at the 1-position may be either α or β)

As the component (B), acetylglucosamine, in which R ¹ , R ² , R ³ and R ⁴ are all hydrogen atoms in the general formula (1), is preferable from the viewpoint of market availability.

A component (B) can be used 1 type or in combination of 2 or more types.
The content of the component (B) is preferably 0.005% by mass or more in the oil-in-water emulsified cosmetic from the viewpoint of suppressing the feeling of slipping and improving the penetration feeling and the stability over time, and 0.01% by mass. The above is more preferable, 0.03% by mass or more is further preferable, 0.12% by mass or less is preferable, 0.09% by mass or less is more preferable, and 0.08% by mass or less is more preferable. Moreover, 0.005-0.12 mass% is preferable in oil-in-water type emulsion cosmetics, and, as for content of a component (B), 0.01-0.09 mass% is more preferable, 0.03-0. More preferred is 08% by mass.

Component (C) is a carboxyvinyl polymer and / or an alkyl-modified carboxyvinyl polymer.
The carboxyvinyl polymer is a water-soluble vinyl polymer having a carboxyl group, and structurally includes acrylic acid as a main chain and allyl sucrose, pentaerythritol, and the like as a crosslinking agent.
Specifically, carbopol 940, carbopol 941, carbopol 980, carbopol 981 (above, manufactured by Lubrizol Advanced Materials), Shintalen L (manufactured by 3V SIGMA), AQPEC HV-501E (manufactured by Sumitomo Seika Co., Ltd.) Commercial products such as can be used.

The alkyl-modified carboxyvinyl polymer is preferably a copolymer of acrylic acid and alkyl (meth) acrylate, and a copolymer of acrylic acid and alkyl (meth) acrylate having an alkyl group having 8 to 30 carbon atoms. Is more preferable, and an acrylic acid / alkyl methacrylate copolymer is more preferable.
Specifically, commercially available products such as Pemlen TR-1, Pemlen TR-2, Carbopol EDT2020, Carbopol 1382 (manufactured by Lubrizol Advanced Materials) can be used.

  These polymers are preferably present as salts by neutralization with a base. Examples of the base include alkali metal hydroxides such as sodium and potassium; ammonium; ammonium derived from alkanolamines such as monoethanolamine, diethanolamine, triethanolamine and tromethamine; and basic amino acids such as arginine and lysine. Alkali metal hydroxides such as potassium are preferred, and potassium hydroxide and sodium hydroxide are more preferred.

  As the component (C), it is preferable to use a carboxyvinyl polymer and an alkyl-modified carboxyvinyl polymer in combination from the viewpoint of storage stability and good skin familiarity. The mass ratio between the carboxyvinyl polymer and the alkyl-modified carboxyvinyl polymer is preferably 1: 1 to 1:10, and more preferably 1: 5 to 1: 9.

A component (C) can be used 1 type or in combination of 2 or more types.
The content of the component (C) is preferably 0.05% by mass or more, and preferably 0.10% by mass or more in the oil-in-water emulsified cosmetic from the viewpoint of suppressing slipping and improving the penetrating feeling and the stability over time. Is more preferable, 0.15 mass% or more is further preferable, 0.8 mass% or less is preferable, 0.6 mass% or less is more preferable, and 0.4 mass% or less is more preferable. Moreover, 0.05-0.8 mass% is preferable in oil-in-water type emulsion cosmetics, and, as for content of a component (C), 0.10-0.6 mass% is more preferable, 0.15-0. More preferably, 4% by mass.

  In the present invention, the mass ratio (B) / (C) of the component (B) to the component (C) improves the stability over time, suppresses the feeling of slipping, and improves the permeability. It is 05 or more, 0.10 or more is preferable, 0.20 or more is more preferable, it is 0.8 or less, 0.6 or less is preferable, and 0.5 or less is more preferable. Moreover, mass ratio (B) / (C) of the component (B) with respect to the component (C) is 0.05 to 0.8, preferably 0.10 to 0.6, and 0.20 to 0.5. Is more preferable.

  Component (D) is a trivalent and / or tetravalent polyhydric alcohol, and specific examples of the trihydric alcohol include glycerin and trimethylolpropane. Examples of the tetrahydric alcohol include diglycerin and pentaerythritol.

A component (D) can be used 1 type or in combination of 2 or more types.
The content of the component (D) is 3% by mass or more in the oil-in-water emulsified cosmetic from the viewpoint of suppressing stickiness and improving moist feeling, penetration, and stability over time, and 4% by mass or more. Preferably, 5 mass% or more is more preferable, it is 20 mass% or less, 15 mass% or less is preferable, and 10 mass% or less is more preferable. Moreover, content of a component (D) is 3-20 mass% in an oil-in-water type emulsion cosmetic, 4-15 mass% is preferable, and 5-10 mass% is more preferable.

  The oil-in-water emulsified cosmetic of the present invention can further contain (E) polysaccharide, and can improve the stability over time. The polysaccharide of component (E) is not limited as long as it is used in ordinary cosmetics, and may be derived from natural products or obtained by chemical synthesis. Polysaccharides derived from natural products are further roughly divided into plant systems, microbial systems, and animal systems.

  In addition, a part of the sugar of the polysaccharide, a polyalkylene oxide group such as an alkyl group, a hydroxyalkyl group, a polyethylene oxide group or a polypropylene oxide group, a saccharide such as glucose, lactose or sucrose, or a polymer comprising these saccharides as a constituent unit Derivatives of polysaccharides obtained by binding can also be included in the polysaccharide of component (E) as equivalent to polysaccharides.

Specifically, examples of plant-based polysaccharides include locust bean gum, guar gum, tamarind gum, quince seed-derived gum, gum arabic, tragacanth gum, caraya gum, carrageenan, alginic acid, pectin, hydroxypropyl guar gum, methylcellulose, hydroxyethylcellulose, Examples thereof include hydroxypropyl cellulose and carboxymethyl cellulose. Examples of microbial polysaccharides include xanthan gum, alkaline genus lats producing polysaccharide, gellan gum, dextran, pullulan and the like. Examples of animal polysaccharides include mucopolysaccharides such as hyaluronic acid, chondroitin sulfate, dermatan sulfate, chitin, and chitosan.
Of these, carrageenan and xanthan gum are preferable, and xanthan gum is more preferable from the viewpoint of suppressing stickiness and improving stability over time.

A component (E) can be used 1 type or in combination of 2 or more types.
The content of the component (E) is preferably 0.005% by mass or more in the oil-in-water emulsified cosmetic from the viewpoint of suppressing the feeling of slipping and improving the penetrating feeling and stability over time, and 0.010% by mass. The above is more preferable, 0.015 mass% or more is further preferable, 0.15 mass% or less is preferable, 0.11 mass% or less is more preferable, and 0.08 mass% or less is further preferable. Moreover, 0.005-0.15 mass% is preferable in oil-in-water type emulsion cosmetics, as for content of a component (E), 0.010-0.11 mass% is more preferable, 0.015-0.1. More preferred is 08% by mass.

  In the present invention, the mass ratio (E) / (C) of the component (E) to the component (C) improves the stability over time, suppresses the feeling of slipping, and improves the permeation. 10 or more is preferable, 0.15 or more is more preferable, 0.20 or more is further preferable, 0.8 or less is preferable, 0.6 or less is more preferable, and 0.4 or less is more preferable. The mass ratio (E) / (C) of the component (E) to the component (C) is preferably 0.10 to 0.8, more preferably 0.15 to 0.6, and 0.20 to 0.0. 4 is more preferable.

The oil-in-water emulsified cosmetic of the present invention can further contain (F) a dihydric alcohol, and can improve moist feeling and penetration while suppressing stickiness.
Examples of the dihydric alcohol include ethylene glycol, 1,3-butylene glycol, propylene glycol, 1,3-propanediol, 1,2-propanediol, dipropylene glycol, polyethylene glycol (weight molecular weight 1500 or less), polypropylene glycol. (Weight molecular weight 1500 or less). Among these, it is preferable to include one or two selected from 1,3-butylene glycol, propylene glycol and dipropylene glycol, and one or two selected from 1,3-butylene glycol and dipropylene glycol. More preferably, it contains seeds, and more preferably contains 1,3-butylene glycol and dipropylene glycol.

The dihydric alcohol of a component (F) can be used 1 type or in combination of 2 or more types.
The content of the dihydric alcohol of component (F) is preferably 1% by mass or more, preferably 3% by mass or more in the oil-in-water emulsified cosmetic from the viewpoint of improving moist feeling and penetration while suppressing stickiness. More preferably, 5 mass% or more is further preferable, 20 mass% or less is preferable, 15 mass% or less is more preferable, and 10 mass% or less is more preferable. Moreover, 1-20 mass% is preferable in oil-in-water type emulsion cosmetics, as for content of a bihydric alcohol, 3-15 mass% is more preferable, and 5-10 mass% is further more preferable.

  In the present invention, the mass ratio (A) / ((D) + (F)) of the component (A) to the total content of the component (D) and the component (F) suppresses the feeling of slipping, moist feeling, film From the viewpoint of improving feeling and penetrability, 0.005 or more is preferable, 0.010 or more is more preferable, 0.015 or more is further preferable, 0.125 or less is preferable, 0.100 or less is more preferable, and 0.10 or less is more preferable. 075 or less is more preferable. Further, the mass ratio (A) / ((D) + (F)) of the component (A) to the total content of the component (D) and the component (F) is preferably 0.005 to 0.125. 010-0.100 is more preferable, and 0.015-0.075 is more preferable.

The oil-in-water emulsified cosmetic of the present invention can further contain (G) a phospholipid, and can improve the stability over time and the moist feeling.
The phospholipid in the present invention is preferably a phospholipid having a phosphatidylcholine content of 60% by mass or more in the phospholipid. A phospholipid having a phosphatidylcholine content of 65% by mass or more, more preferably 70% by mass or more is preferable. Examples of phospholipid components other than phosphatidylcholine include phosphatidic acid, phosphatidylserine, phosphatidylethanolamine, phosphatidylinositol, and phosphatidylglycerol.

  The phospholipid used in the present invention may be a natural product extracted and purified from animals and plants, or may be chemically synthesized, and may be subjected to processing such as hydrogenation or hydroxylation. As a natural product, lecithin, which is an extract / purified product from soybean or egg yolk, is preferable because it is easy to obtain a commercial product. More preferable phospholipids are phospholipids that have been hydrogenated or hydroxylated from the viewpoint of improving the stability over time, and preferably include hydrogenated soybean lecithin and hydrogenated egg yolk lecithin.

  The content of phosphatidylcholine in the phospholipid can be analyzed by a method using thin layer chromatography (TLC), high performance liquid chromatography (HPLC), Iatroscan (manufactured by Yatron) or the like. For example, an organic solvent containing phospholipid described in JP-A-2001-186898 is spotted on TLC, developed with chloroform: methanol: acetic acid = 65: 25: 10, sprayed with 50 wt% ethanol sulfate, and after heating A method of analyzing phospholipids with a densitometer is mentioned. In addition to the above method, any method may be used as long as it can measure and calculate the content and content of phosphatidylcholine contained in the phospholipid.

  Examples of phospholipids containing 60% by mass or more of phosphatidylcholine include coatsome NC-21 (hydrogenated soybean lecithin; manufactured by NOF Corporation), resinol S-10E, and resinol S-10EX (hydrogenated soybean lecithin; Nikko Chemicals). Manufactured).

  A phospholipid may be used independently and may be used in mixture of 2 or more types. The content of the component (G) is preferably 0.01% by mass or more, and 0.05% by mass or more in the oil-in-water emulsion cosmetic from the viewpoint of improving moist feeling and improving stability over time. More preferably, 0.10 mass% or more is further preferable, 1.0 mass% or less is preferable, 0.7 mass% or less is more preferable, and 0.4 mass% or less is further preferable. Moreover, in an oil-in-water type emulsified cosmetic, Preferably it is 0.01-1.0 mass%, More preferably, it is 0.05-0.7 mass%, More preferably, it is 0.10-0.4 mass%. .

  In the present invention, the content of water is preferably 60% by mass or more, more preferably 65% by mass or more, and more preferably 65% by mass or more in the oil-in-water emulsified cosmetic from the viewpoint of improving moist feeling and penetration feeling and suppressing stickiness. % By mass or more is more preferable, 94% by mass or less is preferable, 90% by mass or less is more preferable, and 86% by mass or less is more preferable. The water content is preferably 60 to 94% by mass, more preferably 65 to 90% by mass, and still more preferably 70 to 86% by mass in the oil-in-water emulsion cosmetic.

  The oil-in-water emulsified cosmetic of the present invention is a component other than the above-described components, for example, an oil agent, a surfactant other than the component (G), a polymer compound other than the component (C), and salts. , Chelating agents, pH adjusters, antioxidants, antiseptics, bactericides, antiperspirants, cooling agents, UV absorbers, chemicals, fragrances, various extracts, etc. Can be contained. Each of these agents is not limited to the use as each agent. Depending on the purpose, for example, an antiperspirant may be used as a fragrance, or as a combination with other uses, for example, an antiperspirant. And can be used as an effect as a fragrance.

  The oil-in-water emulsified cosmetic of the present invention can further contain an oil from the viewpoint of improving moist feeling and film feeling. The content of the oil agent is preferably 5% by mass or less, more preferably 3% by mass or less, and more preferably 1.0% by mass in the oil-in-water emulsion cosmetic from the viewpoint of suppressing stickiness and improving the stability over time. The following is more preferable, and 0.6% by mass or less is even more preferable. Here, the oil agent is a hydrophobic substance that is phase-separated from water, and includes oils and fats, hydrocarbon oils, ester oils, higher alcohols, silicone oils, and the like.

  In the oil-in-water emulsified cosmetic of the present invention, a surfactant other than the component (G) can be further contained from the viewpoint of improving aging stability. The content of the surfactant other than the component (G) is preferably 1.0% by mass or less and more preferably 0.6% by mass or less in the oil-in-water emulsion cosmetic from the viewpoint of reducing skin irritation. 0.3 mass% or less is more preferable.

The oil-in-water emulsified cosmetic of the present invention can be produced by a predetermined procedure. For example, the oil-in-water emulsified cosmetic of the present invention is obtained by a method including a step of mixing components (A) to (D), optionally components (E) to (G), water, a neutralizing agent, and optional components together. Can be manufactured.
For example, the step 1 of heating the oil phase component containing the component (G) and, if necessary, the oil phase containing any other oil component and stirring to obtain a preparation;
A step of heating the aqueous phase containing component (A), component (B), component (D), and optionally component (E), component (F), and other optional aqueous components, and stirring to obtain a preparation. 2,
Step 3 in which the preparation obtained in Step 1 is added to the preparation obtained in Step 2 and uniformly dispersed under heating to obtain an emulsion, and
Cooling the emulsion obtained in step 3, adding component (C) and a base within a temperature range of 30 to 50 ° C., and stirring to obtain a preparation; and
The preparation obtained in step 4 can be produced by a method including step 5 of cooling to room temperature (25 ° C.).

The heating temperature in Step 1, Step 2 and Step 3 is preferably 40 ° C. or higher, more preferably 55 ° C. or higher, and preferably 90 ° C. from the viewpoint of sufficiently dissolving the components in the oil phase or aqueous phase. Below, more preferably 85 ° C. or less.
The temperature at which the component (C) and the base in Step 4 are added is within the range of 30 ° C. or more and 50 ° C. or less from the viewpoint of improving the day-to-day stability of the oil-in-water emulsion cosmetic, and the above Step 1 and Step 2 And it is preferable that it is 5 degreeC or more lower than the heating temperature in the process 3, and it is more preferable that it is 10 degreeC or more lower temperature.

The oil-in-water emulsified cosmetic of the present invention can be suitably used for skin, preferably applied to any skin except the scalp, more preferably applied to any of the face, body, limbs and the like. .
The dosage form of the oil-in-water emulsified cosmetic of the present invention is arbitrary, and can be applied as a lotion, milky lotion, cosmetic liquid, cream, base material and the like.

Examples 1-13, Comparative Examples 1-5
Oil-in-water emulsified cosmetics having the composition shown in Table 1 were produced and evaluated for lack of slipperiness, good penetration, good moistness, no stickiness, good film feeling, and stability over time. The results are also shown in Table 1.

〔Production method〕
Step 1. Ingredients 10-12 are mixed, heated to 80 ° C. and mixed with stirring.
Step 2. Ingredients 1, 2, 5-9, 13, and 15 are mixed, heated to 80 ° C., and mixed with stirring.
Step 3. Add the preparation of step 1 while stirring the preparation of step 2.
Step 4. The preparation of step 3 is dispersed with a homomixer (5000 rpm, 3 minutes) and then cooled.
Step 5. After the preparation of step 4 is cooled to 50 ° C., components 3, 4, and 14 are added and dispersed again with a homomixer (5,000 rpm, 3 minutes).
Step 6. The preparation of Step 5 was cooled to 32 ° C. to obtain an oil-in-water emulsion cosmetic.

〔Evaluation method〕
(1) No slipperiness, good penetration, good moistness, no stickiness, good film feeling:
Ten professional panelists applied 1 mL of each oil-in-water emulsified cosmetic to the inner side of the upper arm, spread it over the application area with the entire hand, and carefully applied it. Questionnaires were conducted on “no slippery feeling”, “good permeation” at the time of application, “good moistness”, “no stickiness”, and “good film feeling” after application. For each questionnaire item, sensory evaluation was performed by a five-step evaluation, with 5 points when the effect was very excellent and 1 point when the effect was very poor. The results are shown as the average score (rounded to the second decimal place) of 10 professional panelists.

(2) Daily stability:
(2-1) High temperature stability:
Each oil-in-water emulsified cosmetic was filled in a transparent glass bottle and stored at 45 ° C. for 3 months. During storage, the presence or absence of visual change after 1 month and 3 months was evaluated according to the following criteria.
○: No change in appearance such as separation or discoloration was observed after storage for 3 months.
Δ: No change in appearance such as separation and discoloration after storage for 1 month, and change in appearance such as separation and discoloration is observed after storage for 3 months.
×: Appearance changes such as separation and discoloration are observed after one month.

(2-2) Low temperature stability:
Each oil-in-water emulsified cosmetic was filled in a transparent glass bottle and stored at 0 ° C. for 3 months. During storage, the presence or absence of visual change after 1 month and 3 months was evaluated according to the following criteria.
○: No change in appearance such as precipitation and separation after storage for 3 months.
Δ: No change in appearance such as precipitation and separation after storage for 1 month, and change in appearance such as precipitation and separation after storage for 3 months.
X: Appearance changes such as precipitation and separation were observed after storage for 1 month.

Formulation Example 1 (O / W serum)
An emulsion having the composition shown in Table 2 was produced in the same manner as in Examples 1-13.
The obtained emulsion exhibits an effect equivalent to that of the example.

Formulation Example 2 (O / W emulsion)
O / W type creams having the compositions shown in Table 3 were produced in the same manner as in Examples 1-13.
The obtained O / W type cream exhibits an effect as excellent as that of the example.

The annotated components used in the above examples and formulation examples are the following components.
* 1; Tornale (47% by mass of glycosyl trehalose, manufactured by Hayashibara)
* 2: Marine Sweet F (made by Yaizu Suisan)
* 3: Shintalen L (manufactured by 3V SIGMA)
* 4; PEMULEN TR-1 (manufactured by Lubrizol Advanced Materials)
* 5: Echo gum (made by DSP Gokyo Food & Chemical)
* 6; Cotesome NC-21 (manufactured by NOF Corporation)
* 7; Leistrie Knoll (manufactured by Chikuno Rice Fine Chemicals)
* 8: Dipotassium glycyrrhizinate (Maruzen Pharmaceutical Co., Ltd.)
* 9; ALARIAN (Biotech Marine)
* 10: Moon peach extract BG (Maruzen Pharmaceutical Co., Ltd.)
* 11; N-methyl-L-serine T (manufactured by Takasago Chemical)
* 12: Hyaluronic acid FCH-SU (manufactured by Kibun Food Chemifa)
* 13: PLANDOOL-MAS (manufactured by Nippon Seika Co., Ltd.)
* 14; Niacinamide USP PC (manufactured by DSM Nutritional Products)
* 15: Licorice leaf extract BG (Maruzen Pharmaceutical Co., Ltd.)
* 16: Spruce Liquid B (Ichimaru Falcos)
* 17: Falco Rex Honeysuckle FB (Ichimaru Falcos)
* 18; Green tea extract BGW (Maruzen Pharmaceutical Co., Ltd.)

  Moreover, the fragrance | flavor used by the said prescription example is the following floral system mixing | blending fragrance | flavor prescription. In addition, 1% DPG, 5% DPG, and 10% DPG described in the component names are dipropylene glycol solutions having an active ingredient content of 1% by mass, 5% by mass, and 10% by mass, respectively. Show.

Floral-based blended fragrance formulation (component) Content (mass%)
Bergamot oil (natural fragrance) 2.0
Linarel Acetate 1.5
Methyl anthranilate 0.2
Pettigrain oil (natural flavor) 0.5
Auranthiol 10% DPG (Schiff base of hydroxycitronellal and methylanthranilate) 1.0
Amyl allyl glycolate 1% DPG 0.5
Galvanum oil 1% DPG (natural fragrance) 0.1
Blackcurrant Buzz Absolute 10% DPG (natural fragrance) 1.5
Tadget oil 10% DPG (natural fragrance) 0.8
Ylang Ylang Oil Extra (natural fragrance) 2.0
Benzyl acetate 5.0
Methyl dihydrojasmonate 13.0
Sis Jasmon 10% DPG 1.0
Jasmine absolute (natural fragrance) 0.5
Indole 5% DPG 0.5
Alphahexyl cinnamic aldehyde 1.5
L-citronellol 0.5
Rose oil (natural fragrance) 0.5
Rose Absolute (natural fragrance) 0.5
Damasenone 1% DPG 0.5
L-rose oxide 1% DPG 0.5
Dimethylbenzyl carbonyl acetate 1.0
Hydroxycitronellal 3.0
Liral (compound name: 4- (4-hydroxy-4-methylpentyl) -3-cyclohexene-1-carboxaldehyde) 3.5
Cyclamenaldehyde (Compound name: 2-methyl-3- (4-isopropylphenyl) -propanol) 0.5
Alpha isomethyl ionone (compound name: 5- (2,2,6-trimethyl-2-cyclohexenyl) -3-methyl-3-buten-2-one) 4.0
Oris concrete 10% DPG (natural fragrance) 0.8
Methyl eugenol 0.5
Iso-E super (compound name: 7-acetyl-1,2,3,4,5,6,7,8-octahydro-1,1,6,7-tetramethylnaphthalene) 2.5
Belt Fix Cool (compound name: 4-acetyl-trimethyl-6,8α-ethano-1,2,3,5,6,7,8,8α-octahydronaphthalenone) 4.0
Vetiver Acetate 2.0
Sandalwood oil (natural fragrance) 1.5
Bagdanol 10% DPG (Compound name: 2-ethyl-4- (2,2,3-trimethyl-3-cyclopenten-1-yl) -2-buten-1-ol) 1.0
Patchouli oil 10% DPG (natural fragrance) 0.2
Evernil 10% DPG (Compound name: Methyl-2,4-dihydroxy-3,6-dimethylbenzoate) 1.5
Galac Solid 50% Benzylbenzoate (Compound name: 4,6,6,7,8,8-hexamethyl-1,3,4,6,7,8-hexahydrocyclopentabenzopyran) 10.0
Cyclopentadecanolide 4.0
Heliotropin 0.5
Coumarin 0.5
Vanillin 10% DPG 0.5
Ethyl vanillin 10% DPG 2.5
Raspberry ketone 10% DPG (compound name: 4- (4-hydrophenyl) -2-butanone) 0.5
Gamma undecalactone 10% DPG 1.5
Gamma Decalactone 10% DPG 1.5
Love Danum Absolute 10% DPG (natural fragrance) 0.5
Dipropylene glycol

Claims (7)

The following components (A) to (D):
(A) Glycosyl trehalose 0.10 to 2.0% by mass,
(B) General formula (1)

(Wherein R ¹ represents a hydrogen atom or an alkyl group having 2 to 18 carbon atoms, R ² , R ³ and R ⁴ are the same or different and represent a hydrogen atom or an acyl group having 2 to 18 carbon atoms; (The three-dimensional structure at the 1-position may be either α or β)
Acetylglucosamine or a derivative thereof represented by
(C) carboxyvinyl polymer and / or alkyl-modified carboxyvinyl polymer,
(D) 3-20 mass% of trivalent and / or tetravalent polyhydric alcohol
An oil-in-water emulsion cosmetic in which the mass ratio (B) / (C) of the component (B) to the component (C) is 0.05 to 0.8.   The oil-in-water emulsified cosmetic according to claim 1, wherein the component (C) contains a carboxyvinyl polymer and an alkyl-modified carboxyvinyl polymer.   The oil-in-water emulsified cosmetic according to claim 1 or 2, further comprising (E) a polysaccharide.   The oil-in-water emulsion cosmetic according to claim 3, wherein the mass ratio (E) / (C) of the component (E) to the component (C) is 0.10 to 0.8.   Furthermore, the oil-in-water type emulsified cosmetics of any one of Claims 1-4 which contain 1-20 mass% of (F) dihydric alcohol.   The water ratio of the component (A) to the total content of the component (D) and the component (F) ((A) / (D) + (F)) is 0.005 to 0.125. Oil emulsified cosmetic.   The oil-in-water emulsified cosmetic according to any one of claims 1 to 6, wherein the cosmetic is applied to the skin.