JP2017535546A5 - - Google Patents
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- JP2017535546A5 JP2017535546A5 JP2017525839A JP2017525839A JP2017535546A5 JP 2017535546 A5 JP2017535546 A5 JP 2017535546A5 JP 2017525839 A JP2017525839 A JP 2017525839A JP 2017525839 A JP2017525839 A JP 2017525839A JP 2017535546 A5 JP2017535546 A5 JP 2017535546A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutically acceptable
- acceptable salt
- prodrug
- formula
- trifluoromethyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 125000001246 bromo group Chemical group Br* 0.000 claims description 46
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| WO2002049632A1 (en) * | 2000-12-18 | 2002-06-27 | Institute Of Medicinal Molecular Design. Inc. | Inhibitors against the production and release of inflammatory cytokines |
| WO2003103658A1 (ja) * | 2002-06-05 | 2003-12-18 | 株式会社医薬分子設計研究所 | 免疫関連プロテインキナーゼ阻害剤 |
| US7626042B2 (en) * | 2002-06-06 | 2009-12-01 | Institute Of Medicinal Molecular Design, Inc. | O-substituted hydroxyaryl derivatives |
| EP2543249B1 (en) * | 2007-02-17 | 2018-05-23 | President and Fellows of Harvard College | Compositions and method for tissue preservation |
| WO2009054439A1 (ja) * | 2007-10-23 | 2009-04-30 | Institute Of Medicinal Molecular Design, Inc. | Pai-1産生抑制剤 |
| EP2685972A4 (en) * | 2011-03-14 | 2014-08-13 | Io Therapeutics Inc | TREATMENT OF INFLAMMATORY AND AUTOIMMUNE DISEASES WITH RAR ALPHA SELECTIVE AGONISTS |
| CN104602682B (zh) * | 2012-05-08 | 2018-12-14 | 埃罗米克斯公司 | 用于治疗水通道蛋白介导的疾病的化合物 |
-
2015
- 2015-11-13 AU AU2015346076A patent/AU2015346076A1/en not_active Abandoned
- 2015-11-13 WO PCT/US2015/060731 patent/WO2016077787A1/en not_active Ceased
- 2015-11-13 CN CN201580073130.0A patent/CN107207417A/zh active Pending
- 2015-11-13 SG SG11201703801SA patent/SG11201703801SA/en unknown
- 2015-11-13 US US15/526,706 patent/US20180042873A1/en not_active Abandoned
- 2015-11-13 EP EP15859827.6A patent/EP3218354A4/en not_active Withdrawn
- 2015-11-13 CA CA2966950A patent/CA2966950A1/en not_active Abandoned
- 2015-11-13 JP JP2017525839A patent/JP2017535546A/ja not_active Withdrawn
-
2016
- 2016-05-18 TW TW105115290A patent/TW201716059A/zh unknown
-
2017
- 2017-05-03 IL IL252086A patent/IL252086A0/en unknown
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