JP2017528485A5 - - Google Patents
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- Publication number
- JP2017528485A5 JP2017528485A5 JP2017514665A JP2017514665A JP2017528485A5 JP 2017528485 A5 JP2017528485 A5 JP 2017528485A5 JP 2017514665 A JP2017514665 A JP 2017514665A JP 2017514665 A JP2017514665 A JP 2017514665A JP 2017528485 A5 JP2017528485 A5 JP 2017528485A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- group
- cycloalkyl
- pharmaceutically acceptable
- acceptable salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14185224 | 2014-09-17 | ||
| EP14185224.4 | 2014-09-17 | ||
| PCT/EP2015/070741 WO2016041845A1 (en) | 2014-09-17 | 2015-09-10 | Tetrahydroisoquinoline derivatives and pharmaceutical compositions useful for the treatment of obesity and diabetes |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017528485A JP2017528485A (ja) | 2017-09-28 |
| JP2017528485A5 true JP2017528485A5 (https=) | 2018-10-18 |
| JP6559228B2 JP6559228B2 (ja) | 2019-08-14 |
Family
ID=51564524
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017514665A Expired - Fee Related JP6559228B2 (ja) | 2014-09-17 | 2015-09-10 | 肥満症及び糖尿病の治療に有用なテトラヒドロイソキノリン誘導体及び医薬組成物 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US9340510B2 (https=) |
| EP (1) | EP3194367B1 (https=) |
| JP (1) | JP6559228B2 (https=) |
| WO (1) | WO2016041845A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI3652176T1 (sl) | 2017-07-11 | 2022-04-29 | Boehringer Ingelheim International Gmbh | Substituirani ksantinski derivati |
| US11459324B2 (en) * | 2018-03-14 | 2022-10-04 | Biogen Ma Inc. | O-glycoprotein-2-acetamido-2-deoxy-3-D-glycopyranosidase inhibitors |
| AR122756A1 (es) * | 2020-07-02 | 2022-10-05 | Pfizer | Preparación de un derivado de pirimidinil-3,8-diazabiciclo[3.2.1]octanilmetanona y sal de este |
| EP4434520A4 (en) | 2021-11-19 | 2025-10-29 | Shionogi & Co | PHARMACEUTICAL PRODUCT FOR THE TREATMENT OF HEART DISEASE OR SKELETAL MUSCLE DISEASE |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6455528B1 (en) | 1997-10-14 | 2002-09-24 | Mitsubishi Pharma Corporation | Piperazine compounds and medicinal use thereof |
| BR0010308A (pt) * | 1999-05-06 | 2002-01-08 | Neurogen Corp | Composto, composição farmacêutica, uso de um composto, e, métodos para o tratamento de uma doença ou distúrbio associados com o agonismo patogênico, agonismo inverso ou antagonismo do receptor de gabaa, para localizar receptores de gabaa em uma amostra de tecido, para inibir a ligação de um composto de benzodiazepina a um receptor de gabaa e para alterar a atividade da transdução de sinal dos receptores de gabaa, e, composição farmacêutica embalada |
| JP2004143134A (ja) * | 2002-02-13 | 2004-05-20 | Takeda Chem Ind Ltd | Ｊｎｋ阻害剤 |
| EP1851216A2 (en) * | 2004-11-30 | 2007-11-07 | F.Hoffmann-La Roche Ag | Substituted benzoquinolizines as dpp-iv inhibitors for the treatment of diabetes |
| US7977336B2 (en) | 2006-12-28 | 2011-07-12 | Banyu Pharmaceutical Co. Ltd | Aminopyrimidine derivatives as PLK1 inhibitors |
| US20110009443A1 (en) * | 2008-05-28 | 2011-01-13 | Kevin Daniel Freeman-Cook | Pyrazolospiroketone Acetyl-Coa Carboxylase Inhibitors |
| US20100280067A1 (en) * | 2009-04-30 | 2010-11-04 | Pakala Kumara Savithru Sarma | Inhibitors of acetyl-coa carboxylase |
| US9006450B2 (en) | 2010-07-01 | 2015-04-14 | Boehringer Ingelheim International Gmbh | Compounds, pharmaceutical compositions and uses thereof |
| CN102451178A (zh) | 2010-10-29 | 2012-05-16 | 中国科学院上海药物研究所 | 二氢呋喃-2-酮类化合物在制备抗糖尿病及糖脂代谢药物中的用途 |
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2015
- 2015-09-10 EP EP15760470.3A patent/EP3194367B1/en active Active
- 2015-09-10 JP JP2017514665A patent/JP6559228B2/ja not_active Expired - Fee Related
- 2015-09-10 WO PCT/EP2015/070741 patent/WO2016041845A1/en not_active Ceased
- 2015-09-16 US US14/855,668 patent/US9340510B2/en active Active