JP2017513648A5 - - Google Patents
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- Publication number
- JP2017513648A5 JP2017513648A5 JP2016565018A JP2016565018A JP2017513648A5 JP 2017513648 A5 JP2017513648 A5 JP 2017513648A5 JP 2016565018 A JP2016565018 A JP 2016565018A JP 2016565018 A JP2016565018 A JP 2016565018A JP 2017513648 A5 JP2017513648 A5 JP 2017513648A5
- Authority
- JP
- Japan
- Prior art keywords
- nicotine
- air flow
- nicotine powder
- powder inhaler
- flow channel
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- SNICXCGAKADSCV-JTQLQIEISA-N (-)-Nicotine Chemical compound CN1CCC[C@H]1C1=CC=CN=C1 SNICXCGAKADSCV-JTQLQIEISA-N 0.000 claims 31
- 229960002715 nicotine Drugs 0.000 claims 30
- SNICXCGAKADSCV-UHFFFAOYSA-N nicotine Natural products CN1CCCC1C1=CC=CN=C1 SNICXCGAKADSCV-UHFFFAOYSA-N 0.000 claims 30
- 239000000843 powder Substances 0.000 claims 28
- 210000004072 lung Anatomy 0.000 claims 4
- 238000000034 method Methods 0.000 claims 3
- VZCYOOQTPOCHFL-OWOJBTEDSA-N Fumaric acid Chemical compound OC(=O)\C=C\C(O)=O VZCYOOQTPOCHFL-OWOJBTEDSA-N 0.000 claims 2
- 239000013543 active substance Substances 0.000 claims 2
- 239000002775 capsule Substances 0.000 claims 2
- 239000012530 fluid Substances 0.000 claims 2
- AIBWPBUAKCMKNS-UHFFFAOYSA-N 2-carboxyphenolate;3-(1-methylpyrrolidin-2-yl)pyridin-1-ium Chemical compound OC(=O)C1=CC=CC=C1O.CN1CCCC1C1=CC=CN=C1 AIBWPBUAKCMKNS-UHFFFAOYSA-N 0.000 claims 1
- MMOPGICOOYBFJU-UHFFFAOYSA-N 3-(1-methylpyrrolidin-2-yl)pyridine;2-oxopropanoic acid Chemical compound CC(=O)C(O)=O.CN1CCCC1C1=CC=CN=C1 MMOPGICOOYBFJU-UHFFFAOYSA-N 0.000 claims 1
- HDJBTCAJIMNXEW-PPHPATTJSA-N 3-[(2s)-1-methylpyrrolidin-2-yl]pyridine;hydrochloride Chemical compound Cl.CN1CCC[C@H]1C1=CC=CN=C1 HDJBTCAJIMNXEW-PPHPATTJSA-N 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 230000008878 coupling Effects 0.000 claims 1
- 238000010168 coupling process Methods 0.000 claims 1
- 238000005859 coupling reaction Methods 0.000 claims 1
- 239000001530 fumaric acid Substances 0.000 claims 1
- 229940069688 nicotine bitartrate Drugs 0.000 claims 1
- LDMPZNTVIGIREC-ZGPNLCEMSA-N nicotine bitartrate Chemical compound O.O.OC(=O)[C@H](O)[C@@H](O)C(O)=O.OC(=O)[C@H](O)[C@@H](O)C(O)=O.CN1CCC[C@H]1C1=CC=CN=C1 LDMPZNTVIGIREC-ZGPNLCEMSA-N 0.000 claims 1
- 239000002245 particle Substances 0.000 claims 1
- 230000000149 penetrating effect Effects 0.000 claims 1
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461984967P | 2014-04-28 | 2014-04-28 | |
| EP14166205.6 | 2014-04-28 | ||
| EP14166205 | 2014-04-28 | ||
| US61/984,967 | 2014-04-28 | ||
| PCT/IB2015/000924 WO2015166344A1 (en) | 2014-04-28 | 2015-04-23 | Nicotine powder inhaler |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017513648A JP2017513648A (ja) | 2017-06-01 |
| JP2017513648A5 true JP2017513648A5 (enExample) | 2018-06-07 |
| JP6712231B2 JP6712231B2 (ja) | 2020-06-17 |
Family
ID=50588559
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016565018A Active JP6712231B2 (ja) | 2014-04-28 | 2015-04-23 | ニコチン粉末吸入器 |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US10932492B2 (enExample) |
| EP (1) | EP3136894B1 (enExample) |
| JP (1) | JP6712231B2 (enExample) |
| KR (1) | KR102428026B1 (enExample) |
| CN (1) | CN106163598B (enExample) |
| AU (1) | AU2015254993B2 (enExample) |
| CA (1) | CA2943459C (enExample) |
| ES (1) | ES2743898T3 (enExample) |
| HU (1) | HUE045841T2 (enExample) |
| MX (1) | MX381937B (enExample) |
| PL (1) | PL3136894T3 (enExample) |
| RU (1) | RU2696570C2 (enExample) |
| SG (1) | SG11201608974RA (enExample) |
| TW (1) | TWI653065B (enExample) |
| WO (1) | WO2015166344A1 (enExample) |
| ZA (1) | ZA201606073B (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106170313B (zh) * | 2014-04-28 | 2020-11-10 | 菲利普莫里斯生产公司 | 带香味尼古丁粉末吸入器 |
| HUE045841T2 (hu) | 2014-04-28 | 2020-01-28 | Philip Morris Products Sa | Nikotinpor-inhalátor |
| US9968125B2 (en) | 2015-01-09 | 2018-05-15 | Philip Morris Products S.A. | Nicotine—diketopiperazine microparticle formulations and methods of making the same |
| CN107635612B (zh) * | 2015-04-15 | 2021-09-14 | 菲利普莫里斯生产公司 | 干粉吸入器和使用方法 |
| KR102641134B1 (ko) * | 2015-04-15 | 2024-02-28 | 필립모리스 프로덕츠 에스.에이. | 흡입 디바이스를 위한 향료 요소 |
| US20170071248A1 (en) | 2015-09-16 | 2017-03-16 | Sansa Corporation (Barbados) Inc. | System and Method for Controlling the Harshness of Nicotine-Based Dry Powder Formulations |
| US10149844B2 (en) | 2015-09-16 | 2018-12-11 | Philip Morris Products S.A. | Inhalable nicotine formulations, and methods of making and using thereof |
| US9585835B1 (en) | 2015-09-16 | 2017-03-07 | Sansa Corporation (Barbados) Inc. | Inhalable nicotine formulations and methods of making and using the same |
| US11224594B2 (en) | 2015-09-16 | 2022-01-18 | Philip Morris Products S.A. | Nicotine formulations and methods of making and using the same |
| CN108289841A (zh) | 2015-12-24 | 2018-07-17 | 菲利普莫里斯生产公司 | 带香味尼古丁粉末 |
| EP3669916B1 (en) | 2015-12-24 | 2023-09-06 | Philip Morris Products S.A. | Nicotine powder delivery system |
| SG11201805204WA (en) * | 2015-12-24 | 2018-07-30 | Philip Morris Products Sa | Nicotine particle capsule |
| EP3589146B1 (en) | 2017-02-28 | 2023-04-05 | Philip Morris Products S.A. | Aerosol-generating device comprising a powder de-agglomerating actuator |
| GB2604314A (en) * | 2017-09-22 | 2022-09-07 | Nerudia Ltd | Device, system and method |
| KR102804090B1 (ko) * | 2019-03-05 | 2025-05-07 | 필립모리스 프로덕츠 에스.에이. | 흡입기 물품용 관통 장치 |
| US12082611B2 (en) | 2019-05-24 | 2024-09-10 | Imperial Tobacco Limited | Aerosol delivery device |
| EP3741235A1 (en) * | 2019-05-24 | 2020-11-25 | Nerudia Limited | Aerosol delivery device |
| CN120417886A (zh) * | 2022-10-27 | 2025-08-01 | 韩国烟草人参公社 | 含有止咳剂的干粉吸入器用棒状件及包括其的干粉吸入器 |
| KR102824242B1 (ko) * | 2022-11-02 | 2025-06-25 | 주식회사 케이티앤지 | 흡입기 |
| CN116183430A (zh) * | 2022-12-30 | 2023-05-30 | 深圳市吉迩科技有限公司 | 尼古丁的测定系统、方法、装置、计算机设备及存储介质 |
| KR20240162737A (ko) * | 2023-05-09 | 2024-11-18 | 주식회사 케이티앤지 | 파우더 카트리지를 포함하는 흡입기 |
Family Cites Families (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4655229A (en) | 1984-01-30 | 1987-04-07 | R. J. Reynolds Tobacco Company | Flavor delivery system |
| US4597961A (en) * | 1985-01-23 | 1986-07-01 | Etscorn Frank T | Transcutaneous application of nicotine |
| US4735217A (en) * | 1986-08-21 | 1988-04-05 | The Procter & Gamble Company | Dosing device to provide vaporized medicament to the lungs as a fine aerosol |
| NO168921C (no) * | 1989-07-31 | 1992-04-22 | Svein Knudsen | Roekfri sigaretterstatning til bruk ved roekavvenning ellertil bruk i roekfrie miljoeer |
| US5167242A (en) * | 1990-06-08 | 1992-12-01 | Kabi Pharmacia Aktiebolaq | Nicotine-impermeable container and method of fabricating the same |
| US6098632A (en) * | 1992-11-25 | 2000-08-08 | Pharmacia & Upjohn Ab | Nicotine-impermeable container and method of fabricating the same |
| US5441060A (en) * | 1993-02-08 | 1995-08-15 | Duke University | Dry powder delivery system |
| CA2146954C (en) * | 1995-04-12 | 2008-06-17 | Arthur Slutsky | Breath activated nicotine inhalers |
| CA2231968A1 (en) | 1998-03-11 | 1999-09-11 | Smoke-Stop, A Partnership Consisting Of Art Slutsky | Method of producing a nicotine medicament |
| EP1066074A1 (en) | 1998-03-16 | 2001-01-10 | Inhale Therapeutic Systems, Inc. | Aerosolized active agent delivery |
| US6234169B1 (en) | 1998-08-14 | 2001-05-22 | Arthur Slutsky | Inhaler |
| US8256433B2 (en) | 1999-07-16 | 2012-09-04 | Aradigm Corporation | Systems and methods for effecting cessation of tobacco use |
| AU2001234005B2 (en) * | 2000-02-28 | 2006-01-19 | Pharmakodex Limited | Improvements in or relating to the delivery of oral drugs |
| JP3974748B2 (ja) * | 2000-11-29 | 2007-09-12 | 株式会社日立製作所 | 粉体吸引具 |
| US6722364B2 (en) * | 2001-01-12 | 2004-04-20 | Becton, Dickinson And Company | Medicament inhalation delivery devices and methods for using the same |
| US6644309B2 (en) | 2001-01-12 | 2003-11-11 | Becton, Dickinson And Company | Medicament respiratory delivery device and method |
| US6443152B1 (en) * | 2001-01-12 | 2002-09-03 | Becton Dickinson And Company | Medicament respiratory delivery device |
| CA2483218C (en) | 2002-04-25 | 2012-07-10 | Nektar Therapeutics Uk Ltd | Particulate materials |
| US6904908B2 (en) | 2002-05-21 | 2005-06-14 | Trudell Medical International | Visual indicator for an aerosol medication delivery apparatus and system |
| US20040206350A1 (en) * | 2002-12-19 | 2004-10-21 | Nektar Therapeutics | Aerosolization apparatus with non-circular aerosolization chamber |
| US20060147389A1 (en) * | 2004-04-14 | 2006-07-06 | Vectura Ltd. | Devices and pharmaceutical compositions for enhancing dosing efficiency |
| US20040204439A1 (en) | 2003-04-14 | 2004-10-14 | Staniforth John Nicholas | Composition, device, and method for treating sexual dysfunction via inhalation |
| CN2609565Y (zh) | 2003-06-10 | 2004-04-07 | 中国人民解放军264医院 | Sars病人吸氧呼出病毒收集器 |
| EP1635762B1 (en) * | 2003-06-13 | 2021-03-03 | Civitas Therapeutics, Inc. | Low dose pharmaceutical powders for inhalation |
| AU2004291542A1 (en) | 2003-11-18 | 2005-06-02 | Yansong Shan | Healthy pleasurable inhalation device |
| DE10356925B4 (de) * | 2003-12-05 | 2006-05-11 | Lts Lohmann Therapie-Systeme Ag | Inhalator für basische pharmazeutische Wirkstoffe sowie Verfahren für dessen Herstellung |
| US7832399B2 (en) * | 2006-03-10 | 2010-11-16 | One Dose, Llc | Medication inhaler |
| US8360057B2 (en) | 2006-03-10 | 2013-01-29 | Dose One, Llc | Medication inhaler for dispensing multiple capsules |
| GB2461008B (en) | 2006-12-08 | 2011-08-10 | Exchange Supplies Ltd | Nicotine inhalation device |
| US10668058B2 (en) | 2007-03-30 | 2020-06-02 | Philip Morris Products S.A. | Device and method for delivery of a medicament |
| KR101257597B1 (ko) | 2009-02-23 | 2013-04-26 | 니뽄 다바코 산교 가부시키가이샤 | 비가열형 담배 향미 흡인기 |
| GB0908129D0 (en) | 2009-05-12 | 2009-06-24 | Innovata Ltd | Composition |
| PL2609822T3 (pl) | 2010-08-24 | 2018-11-30 | Japan Tobacco, Inc. | Inhalator aromatu typu niegrzejnego i sposób wytwarzania wkładu aromatu |
| EP2611484A4 (en) | 2010-09-02 | 2016-03-09 | Sipnose Ltd | DEVICE FOR NASAL ADMINISTRATION |
| JP6050758B2 (ja) * | 2010-12-07 | 2016-12-21 | レスピラ セラピューティクス インコーポレイテッドRespira Therapeutics,Inc. | 乾燥粉末吸入器及びその作動方法 |
| GB2497616A (en) | 2011-12-13 | 2013-06-19 | Cn Creative Ltd | Flavoured inhalation device |
| US10549052B2 (en) * | 2012-02-28 | 2020-02-04 | Sipnose Ltd. | Nasal delivery device |
| US20150343159A1 (en) * | 2012-07-05 | 2015-12-03 | Glaxo Group Limited | Inhaler Device |
| US20140088044A1 (en) * | 2012-09-21 | 2014-03-27 | Basil Rigas | Product comprising a nicotine-containing material and an anti-cancer agent |
| CN103566444B (zh) * | 2013-11-12 | 2015-04-15 | 江苏大学 | 一种医用盐雾测控仪及盐雾浓度定量控制方法 |
| CN106170313B (zh) * | 2014-04-28 | 2020-11-10 | 菲利普莫里斯生产公司 | 带香味尼古丁粉末吸入器 |
| HUE045841T2 (hu) | 2014-04-28 | 2020-01-28 | Philip Morris Products Sa | Nikotinpor-inhalátor |
-
2015
- 2015-04-23 HU HUE15751065A patent/HUE045841T2/hu unknown
- 2015-04-23 MX MX2016014089A patent/MX381937B/es unknown
- 2015-04-23 AU AU2015254993A patent/AU2015254993B2/en active Active
- 2015-04-23 ES ES15751065T patent/ES2743898T3/es active Active
- 2015-04-23 SG SG11201608974RA patent/SG11201608974RA/en unknown
- 2015-04-23 WO PCT/IB2015/000924 patent/WO2015166344A1/en not_active Ceased
- 2015-04-23 CA CA2943459A patent/CA2943459C/en active Active
- 2015-04-23 KR KR1020167027861A patent/KR102428026B1/ko active Active
- 2015-04-23 PL PL15751065T patent/PL3136894T3/pl unknown
- 2015-04-23 US US15/124,562 patent/US10932492B2/en active Active
- 2015-04-23 EP EP15751065.2A patent/EP3136894B1/en active Active
- 2015-04-23 RU RU2016146351A patent/RU2696570C2/ru not_active Application Discontinuation
- 2015-04-23 JP JP2016565018A patent/JP6712231B2/ja active Active
- 2015-04-23 CN CN201580019505.5A patent/CN106163598B/zh active Active
- 2015-04-24 TW TW104113148A patent/TWI653065B/zh active
-
2016
- 2016-09-01 ZA ZA2016/06073A patent/ZA201606073B/en unknown
-
2021
- 2021-02-05 US US17/168,417 patent/US11878114B2/en active Active
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