JP2017513515A5 - - Google Patents
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- JP2017513515A5 JP2017513515A5 JP2017500434A JP2017500434A JP2017513515A5 JP 2017513515 A5 JP2017513515 A5 JP 2017513515A5 JP 2017500434 A JP2017500434 A JP 2017500434A JP 2017500434 A JP2017500434 A JP 2017500434A JP 2017513515 A5 JP2017513515 A5 JP 2017513515A5
- Authority
- JP
- Japan
- Prior art keywords
- predetermined reference
- eli
- haadms
- score
- expression
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 108090000623 proteins and genes Proteins 0.000 claims 6
- 238000011284 combination treatment Methods 0.000 claims 4
- 229940121372 histone deacetylase inhibitor Drugs 0.000 claims 4
- 239000003276 histone deacetylase inhibitor Substances 0.000 claims 4
- 229940126190 DNA methyltransferase inhibitor Drugs 0.000 claims 3
- 239000003968 dna methyltransferase inhibitor Substances 0.000 claims 3
- 208000034578 Multiple myelomas Diseases 0.000 claims 2
- 206010035226 Plasma cell myeloma Diseases 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 229940079593 drug Drugs 0.000 claims 2
- 108060004795 Methyltransferase Proteins 0.000 claims 1
- 102000016397 Methyltransferase Human genes 0.000 claims 1
- 239000012472 biological sample Substances 0.000 claims 1
- 230000005764 inhibitory process Effects 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 238000010998 test method Methods 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14305404.7 | 2014-03-21 | ||
| EP14305404 | 2014-03-21 | ||
| PCT/EP2015/055992 WO2015140321A1 (en) | 2014-03-21 | 2015-03-20 | Methods for predicting response to hdaci/dnmti combination in multiple myeloma |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017513515A JP2017513515A (ja) | 2017-06-01 |
| JP2017513515A5 true JP2017513515A5 (enExample) | 2018-04-26 |
| JP6679561B2 JP6679561B2 (ja) | 2020-04-15 |
Family
ID=50434142
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017500434A Active JP6679561B2 (ja) | 2014-03-21 | 2015-03-20 | 多発性骨髄腫におけるＨＤＡＣｉ／ＤＮＭＴｉの組み合わせに対する応答を予測する方法 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US10662481B2 (enExample) |
| EP (1) | EP3119907B1 (enExample) |
| JP (1) | JP6679561B2 (enExample) |
| WO (1) | WO2015140321A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL277025B2 (en) * | 2018-03-02 | 2024-04-01 | Vertex Pharma | Methods of enhancing stem cell differentiation into beta cells |
| CN114708963B (zh) * | 2022-03-31 | 2025-07-15 | 中南大学 | 肺腺癌患者生存期预后评估方法、计算机装置及存储介质 |
| CN115011694A (zh) * | 2022-06-08 | 2022-09-06 | 中国科学院苏州生物医学工程技术研究所 | 用于鉴定样本中失调基因的方法、试剂盒 |
| CN116953240B (zh) * | 2023-08-03 | 2025-09-16 | 中国医学科学院基础医学研究所 | 多发性骨髓瘤的预后标志物及其应用 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10174380B2 (en) | 2012-10-08 | 2019-01-08 | Inserm (Institut National De La Sante Et De La Recherche Medicale) | Methods for predicting multiple myeloma treatment response |
-
2015
- 2015-03-20 JP JP2017500434A patent/JP6679561B2/ja active Active
- 2015-03-20 WO PCT/EP2015/055992 patent/WO2015140321A1/en not_active Ceased
- 2015-03-20 US US15/127,803 patent/US10662481B2/en active Active
- 2015-03-20 EP EP15741765.0A patent/EP3119907B1/en active Active
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