JP2017510596A - 皮膚病態を治療するための組成物 - Google Patents
皮膚病態を治療するための組成物 Download PDFInfo
- Publication number
- JP2017510596A JP2017510596A JP2016561275A JP2016561275A JP2017510596A JP 2017510596 A JP2017510596 A JP 2017510596A JP 2016561275 A JP2016561275 A JP 2016561275A JP 2016561275 A JP2016561275 A JP 2016561275A JP 2017510596 A JP2017510596 A JP 2017510596A
- Authority
- JP
- Japan
- Prior art keywords
- weight
- acne
- composition
- months
- composition comprises
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
- A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
- A61K31/355—Tocopherols, e.g. vitamin E
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/55—Phosphorus compounds
- A61K8/553—Phospholipids, e.g. lecithin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/676—Ascorbic acid, i.e. vitamin C
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/678—Tocopherol, i.e. vitamin E
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dermatology (AREA)
- Birds (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Biophysics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Description
本出願は、2014年4月9日に出願された「COMPOSITIONS AND METHODS OF USING SAME」と題する米国仮特許出願第61/977,231号の利益を主張し、その内容は全て本明細書に参照によって組み込まれる。
本開示は一般に、ざ瘡または関連する皮膚病態などの疾患及び/または障害の治療のための組成物に関する。
局所的に適用された組成物の有効性及び安全性と、軽度から中等度の尋常性ざ瘡を有する患者における脂肪酸組成物(試験物品1及び2)ならびに第3の組成物(試験物品3)の2つの用量間の用量応答関係とを調査するために、無作為化、プラセボ対照、二重盲検、並行群、多施設、第II相試験を実行した。
試験物品1、1日2回12週間、全ての患部に局所的に適用、
試験物品2、1日2回12週間、全ての患部に局所的に適用、
試験物品3、1日2回12週間、全ての患部に局所的に適用。
表1 試験来院スケジュール
Claims (5)
- 皮膚病態を治療または予防することを必要とする対象において、前記皮膚病態を治療または予防するための方法であって、前記対象に、パルミチン酸アスコルビル、トコフェロール、アスコルビン酸、及びレシチンを含む組成物を投与することを含む、方法。
- 前記皮膚病態が、ざ瘡病態である、請求項1に記載の方法。
- 前記パルミチン酸アスコルビル、トコフェロール、アスコルビン酸、及びレシチンがそれぞれ、前記組成物の約0.01重量%〜約5重量%、約0.05重量%〜約2.5重量%、または約0.075重量%〜約1重量%の量で存在する、請求項1に記載の方法。
- パルミチン酸アスコルビル、トコフェロール、アスコルビン酸、及びレシチンを含む、局所用組成物。
- 1つ以上の賦形剤を更に含む、請求項4に記載の組成物。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201461977231P | 2014-04-09 | 2014-04-09 | |
US61/977,231 | 2014-04-09 | ||
PCT/IB2015/001990 WO2016005823A2 (en) | 2014-04-09 | 2015-04-09 | Compositions and methods of using same |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2017510596A true JP2017510596A (ja) | 2017-04-13 |
JP2017510596A5 JP2017510596A5 (ja) | 2018-05-24 |
Family
ID=54264160
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2016561275A Ceased JP2017510596A (ja) | 2014-04-09 | 2015-04-09 | 皮膚病態を治療するための組成物 |
Country Status (5)
Country | Link |
---|---|
US (2) | US20150290225A1 (ja) |
EP (1) | EP3129029A2 (ja) |
JP (1) | JP2017510596A (ja) |
MA (1) | MA39718A (ja) |
WO (1) | WO2016005823A2 (ja) |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS63225689A (ja) * | 1987-02-09 | 1988-09-20 | ロレアル | 新規な酸化防止剤組成物、及び、これを含有する脂肪性物質含有組成物及び化粧料組成物 |
JP2007204414A (ja) * | 2006-02-01 | 2007-08-16 | Jukobi Kk | 化粧料組成物及びニキビ改善用化粧料 |
US20080070875A1 (en) * | 2006-09-11 | 2008-03-20 | Majewski George P | Acne treatment compositions and methods of use |
JP2010502662A (ja) * | 2006-09-08 | 2010-01-28 | ディーエスエム アイピー アセッツ ビー.ブイ. | スキンケア組成物 |
JP2011057578A (ja) * | 2009-09-08 | 2011-03-24 | Noevir Co Ltd | 過酸化脂質抑制剤及び皮膚外用剤 |
WO2013057284A1 (en) * | 2011-10-19 | 2013-04-25 | Dignity Sciences Limited | Pharmaceutical compositions comprising dgla, 15-ohepa, and/or 15-hetre and methods of use thereof |
WO2013124479A1 (en) * | 2012-02-23 | 2013-08-29 | Dignity Sciences Limited | Pharmaceutical compositions comprising dgla, 15-ohepa, and/or 15-hetre and methods of reducing sebum production using same |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2059880T3 (es) * | 1990-05-23 | 1994-11-16 | Nestle Sa | Utilizacion del acido estearidonico para el tratamiento de las enfermedades inflamatorias. |
US7074832B2 (en) * | 2001-09-24 | 2006-07-11 | Bradley Pharmaceuticals, Inc. | Compositions containing antimicrobials and urea for the treatment of dermatological disorders and methods for their use |
DE10337863A1 (de) * | 2003-08-18 | 2005-03-17 | Merck Patent Gmbh | Verwendung von Chromen-4-on-Derivaten |
US20050287199A1 (en) * | 2004-06-28 | 2005-12-29 | Teresa Ann Denney | Therapeutic micro nutrient composition for lipolysis and drug delivery |
WO2006056308A2 (de) * | 2004-11-25 | 2006-06-01 | Merck Patent Gmbh | Flavonoid-komplexe mit cyclodextrinen |
EA200870001A1 (ru) * | 2005-05-12 | 2009-10-30 | Мартек Байосайенсиз Корпорейшн | Гидролизат биомассы, его применение и производство |
US20090253785A1 (en) * | 2007-01-22 | 2009-10-08 | Tai-Li Ou | Bactericide composition |
-
2015
- 2015-04-08 MA MA039718A patent/MA39718A/fr unknown
- 2015-04-09 EP EP15800945.6A patent/EP3129029A2/en not_active Withdrawn
- 2015-04-09 WO PCT/IB2015/001990 patent/WO2016005823A2/en active Application Filing
- 2015-04-09 US US14/682,966 patent/US20150290225A1/en not_active Abandoned
- 2015-04-09 JP JP2016561275A patent/JP2017510596A/ja not_active Ceased
-
2017
- 2017-05-04 US US15/587,125 patent/US20170232021A1/en not_active Abandoned
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS63225689A (ja) * | 1987-02-09 | 1988-09-20 | ロレアル | 新規な酸化防止剤組成物、及び、これを含有する脂肪性物質含有組成物及び化粧料組成物 |
JP2007204414A (ja) * | 2006-02-01 | 2007-08-16 | Jukobi Kk | 化粧料組成物及びニキビ改善用化粧料 |
JP2010502662A (ja) * | 2006-09-08 | 2010-01-28 | ディーエスエム アイピー アセッツ ビー.ブイ. | スキンケア組成物 |
US20080070875A1 (en) * | 2006-09-11 | 2008-03-20 | Majewski George P | Acne treatment compositions and methods of use |
JP2011057578A (ja) * | 2009-09-08 | 2011-03-24 | Noevir Co Ltd | 過酸化脂質抑制剤及び皮膚外用剤 |
WO2013057284A1 (en) * | 2011-10-19 | 2013-04-25 | Dignity Sciences Limited | Pharmaceutical compositions comprising dgla, 15-ohepa, and/or 15-hetre and methods of use thereof |
WO2013124479A1 (en) * | 2012-02-23 | 2013-08-29 | Dignity Sciences Limited | Pharmaceutical compositions comprising dgla, 15-ohepa, and/or 15-hetre and methods of reducing sebum production using same |
Also Published As
Publication number | Publication date |
---|---|
US20170232021A1 (en) | 2017-08-17 |
MA39718A (fr) | 2017-02-15 |
US20150290225A1 (en) | 2015-10-15 |
WO2016005823A3 (en) | 2016-03-17 |
EP3129029A2 (en) | 2017-02-15 |
WO2016005823A2 (en) | 2016-01-14 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US8293790B2 (en) | Pharmaceutical compositions comprising DGLA and benzoyl peroxide and methods of use thereof | |
JP2015508094A (ja) | Dgla、15−ohepa、及び/又は15−hetreを含む医薬組成物並びにこれを使用する皮脂生成の低減法 | |
US20130131177A1 (en) | Use of a dermatological composition comprising a combination of adapalene and benzoyl peroxide which is intended for the treatment of acne in non-caucasian population with decrease of post-inflammatory hyperpigmentation | |
US20080057138A1 (en) | Restorative skin cream | |
CA3061545A1 (en) | Skin care composition | |
US20190151394A1 (en) | Prebiotic Acne Treatment | |
JP2011011993A (ja) | ニキビ治療薬 | |
US20200030398A1 (en) | Skin care composition | |
CA3040867C (en) | Halobetasol propionate compositions | |
KR20110138709A (ko) | 5-아미노레불린산 또는 이의 에스테르를 포함하는 여드름 개선용 조성물 | |
JP2015513558A (ja) | 美容組成物 | |
JP2017510596A (ja) | 皮膚病態を治療するための組成物 | |
EP3378474B1 (en) | Composition for the use in the treatment of plantar hyperhidrosis predisposing to cutaneous fungal infection of the foot | |
ITUB20159582A1 (it) | Composizione, per uso topico, utile per la prevenzione di disturbi di tipo infiammatorio e/o infettivo delle mucose. | |
JP2006515873A (ja) | 哺乳類の皮膚科病変の治療及び/又は予防におけるビタミンk1酸化物又はその誘導体を含有する組成物の使用 | |
RU2722823C2 (ru) | Косметический состав для лечения и профилактики акне на коже | |
US20160184220A1 (en) | Method for the Prevention and Treatment of Acne | |
Kadam et al. | An Overview: Acne Vulgaris | |
JP2024516652A (ja) | 過酸化ベンゾイルおよびアゼライン酸を含む外用剤およびその使用 | |
Draelos | Treatments for sensitive skin: An update | |
Trupti et al. | An Overview: Acne Vulgaris | |
JP2018002652A (ja) | 慢性角化型湿疹改善剤 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A711 | Notification of change in applicant |
Free format text: JAPANESE INTERMEDIATE CODE: A711 Effective date: 20170728 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20180404 |
|
A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20180404 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20181218 |
|
A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20181221 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20190315 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20190827 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20191126 |
|
A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20200421 |
|
A045 | Written measure of dismissal of application [lapsed due to lack of payment] |
Free format text: JAPANESE INTERMEDIATE CODE: A045 Effective date: 20200901 |