JP2017506352A - 溶液と接触するナノ電子デバイスを安定化するための方法、装置およびシステム - Google Patents

溶液と接触するナノ電子デバイスを安定化するための方法、装置およびシステム Download PDF

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JP2017506352A
JP2017506352A JP2016570936A JP2016570936A JP2017506352A JP 2017506352 A JP2017506352 A JP 2017506352A JP 2016570936 A JP2016570936 A JP 2016570936A JP 2016570936 A JP2016570936 A JP 2016570936A JP 2017506352 A JP2017506352 A JP 2017506352A
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electrode
sensing
sensing electrode
reference electrode
gap
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スチュアート リンジー,
スチュアート リンジー,
ペイ パン,
ペイ パン,
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Arizona State University ASU
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416Systems
    • G01N27/4163Systems checking the operation of, or calibrating, the measuring apparatus
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/48707Physical analysis of biological material of liquid biological material by electrical means
    • G01N33/48721Investigating individual macromolecules, e.g. by translocation through nanopores
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869Methods for sequencing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28Electrolytic cell components
    • G01N27/30Electrodes, e.g. test electrodes; Half-cells
    • G01N27/301Reference electrodes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/403Cells and electrode assemblies
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416Systems
    • G01N27/48Systems using polarography, i.e. measuring changes in current under a slowly-varying voltage

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
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  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
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  • General Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
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  • Electrochemistry (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Nanotechnology (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
JP2016570936A 2014-02-25 2015-02-25 溶液と接触するナノ電子デバイスを安定化するための方法、装置およびシステム Ceased JP2017506352A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461944322P 2014-02-25 2014-02-25
US61/944,322 2014-02-25
PCT/US2015/017519 WO2015130781A1 (en) 2014-02-25 2015-02-25 Methods, apparatuses and systems for stabilizing nano-electronic devices in contact with solutions

Related Child Applications (1)

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JP2018016278A Division JP2018066764A (ja) 2014-02-25 2018-02-01 溶液と接触するナノ電子デバイスを安定化するための方法、装置およびシステム

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JP2017506352A true JP2017506352A (ja) 2017-03-02

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JP2018016278A Pending JP2018066764A (ja) 2014-02-25 2018-02-01 溶液と接触するナノ電子デバイスを安定化するための方法、装置およびシステム

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US (2) US20170016852A1 (https=)
JP (2) JP2017506352A (https=)
WO (1) WO2015130781A1 (https=)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5838474B2 (ja) 2010-02-02 2016-01-06 アリゾナ ボード オブ リージェンツ オン ビハーフ オブ アリゾナ ステート ユニバーシティ ポリマーの配列を決定するための制御されたトンネルギャップデバイス
WO2013116509A1 (en) 2012-02-01 2013-08-08 Arizona Board Of Regents Acting For And On Behalf Of Arizona State University Systems, apparatuses and methods for reading an amino acid sequence
EP2906720A4 (en) 2012-10-10 2016-06-01 Univ Arizona MOLECULAR BASED SYSTEMS AND DEVICES AND METHOD FOR PRODUCING THEM
EP2965073B1 (en) 2013-03-05 2018-10-31 Arizona Board Of Regents Acting For And On Behalf Of State Arizona University Translocation of a polymer through a nanopore
WO2015126963A1 (en) 2014-02-18 2015-08-27 Arizona Board Of Regents Acting For And On Behalf Of Arizona State University A three arm y-shaped bisbiotin ligand
US10145846B2 (en) 2014-04-16 2018-12-04 Arizona Board Of Regents On Behalf Of Arizona State University Digital protein sensing chip and methods for detection of low concentrations of molecules
US10287257B2 (en) 2014-05-07 2019-05-14 Arizona Board Of Regents On Behalf Of Arizona State University Linker molecule for multiplex recognition by atomic force microscopy (AFM)
CN104792845A (zh) * 2014-08-07 2015-07-22 中国科学院微电子研究所 传感装置
US10422787B2 (en) 2015-12-11 2019-09-24 Arizona Board Of Regents On Behalf Of Arizona State University System and method for single molecule detection
US10379102B2 (en) 2015-12-11 2019-08-13 Arizona Board Of Regents On Behalf Of Arizona State University System and method for single molecule detection
CA3135743A1 (en) 2018-05-09 2019-11-14 Arizona Board Of Regents On Behalf Of Arizona State University Method for electronic detection and quantification of antibodies
SG11202011394WA (en) 2018-05-17 2020-12-30 Stuart Lindsay Device, system and method for direct electrical measurement of enzyme activity
WO2020160300A2 (en) 2019-01-30 2020-08-06 Stuart Lindsay Bioelectronic circuits, systems and methods for preparing and using them
KR20220147602A (ko) 2020-02-28 2022-11-03 아리조나 보드 오브 리젠츠 온 비하프 오브 아리조나 스테이트 유니버시티 생체고분자를 시퀀싱하는 방법
WO2021211950A1 (en) 2020-04-17 2021-10-21 Arizona Board Of Regents On Behalf Of Arizona State University Single-molecule electronic sequence detector and methods of use
KR20230005866A (ko) 2020-04-30 2023-01-10 아리조나 보드 오브 리젠츠 온 비하프 오브 아리조나 스테이트 유니버시티 바이오폴리머 시퀀싱 방법
EP4158063A4 (en) 2020-05-29 2024-05-29 Arizona Board of Regents on behalf of Arizona State University BIOELECTRONIC DEVICES WITH PROGRAMMABLE ADAPTERS

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011527191A (ja) * 2008-07-07 2011-10-27 オックスフォード ナノポア テクノロジーズ リミテッド 塩基検出細孔
US20120193231A1 (en) * 2011-01-28 2012-08-02 International Business Machines Corporation Dna sequencing using multiple metal layer structure with organic coatings forming transient bonding to dna bases
JP2013505448A (ja) * 2009-09-18 2013-02-14 プレジデント アンド フェロウズ オブ ハーバード カレッジ 高感度分子検出及び分析を可能にする、ナノポアを有するベアの単層グラフェン膜
JP2013036865A (ja) * 2011-08-09 2013-02-21 Hitachi High-Technologies Corp ナノポア式分析装置
WO2013116509A1 (en) * 2012-02-01 2013-08-08 Arizona Board Of Regents Acting For And On Behalf Of Arizona State University Systems, apparatuses and methods for reading an amino acid sequence

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7279337B2 (en) * 2004-03-10 2007-10-09 Agilent Technologies, Inc. Method and apparatus for sequencing polymers through tunneling conductance variation detection
DE102004025580A1 (de) * 2004-05-25 2005-12-22 Infineon Technologies Ag Sensor-Anordnung, Sensor-Array und Verfahren zum Herstellen einer Sensor-Anordnung
WO2008124706A2 (en) * 2007-04-06 2008-10-16 Arizona Board Of Regents Acting For And On Behalf Of Arizona State University Devices and methods for target molecule characterization
US8860438B2 (en) * 2009-05-11 2014-10-14 Clemson University Research Foundation Electrical double layer capacitive devices and methods of using same for sequencing polymers and detecting analytes
US8986524B2 (en) * 2011-01-28 2015-03-24 International Business Machines Corporation DNA sequence using multiple metal layer structure with different organic coatings forming different transient bondings to DNA
CN103842519B (zh) * 2011-04-04 2018-02-06 哈佛大学校长及研究员协会 通过局部电位测量进行的纳米孔感测
US20130302901A1 (en) * 2012-04-04 2013-11-14 Stuart Lindsay Electrodes for Sensing Chemical Composition
KR20130114435A (ko) * 2012-04-09 2013-10-17 삼성전자주식회사 다수의 전극을 갖는 생분자 검출 장치
US10881339B2 (en) * 2012-06-29 2021-01-05 Dexcom, Inc. Use of sensor redundancy to detect sensor failures

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011527191A (ja) * 2008-07-07 2011-10-27 オックスフォード ナノポア テクノロジーズ リミテッド 塩基検出細孔
JP2013505448A (ja) * 2009-09-18 2013-02-14 プレジデント アンド フェロウズ オブ ハーバード カレッジ 高感度分子検出及び分析を可能にする、ナノポアを有するベアの単層グラフェン膜
US20120193231A1 (en) * 2011-01-28 2012-08-02 International Business Machines Corporation Dna sequencing using multiple metal layer structure with organic coatings forming transient bonding to dna bases
JP2013036865A (ja) * 2011-08-09 2013-02-21 Hitachi High-Technologies Corp ナノポア式分析装置
WO2013116509A1 (en) * 2012-02-01 2013-08-08 Arizona Board Of Regents Acting For And On Behalf Of Arizona State University Systems, apparatuses and methods for reading an amino acid sequence

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
PING XIE, ET AL.: "Local Electrical Potential Detection of DNA by Nanowire-Nanopore Sensors", NATURE NANOTECHNOLOGY, vol. 7, JPN7017002906, February 2012 (2012-02-01), pages 119 - 125, ISSN: 0003637279 *

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US20180224395A1 (en) 2018-08-09
US20170016852A1 (en) 2017-01-19
WO2015130781A9 (en) 2015-11-05
JP2018066764A (ja) 2018-04-26
WO2015130781A1 (en) 2015-09-03

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