JP2017506352A - 溶液と接触するナノ電子デバイスを安定化するための方法、装置およびシステム - Google Patents

溶液と接触するナノ電子デバイスを安定化するための方法、装置およびシステム Download PDF

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JP2017506352A
JP2017506352A JP2016570936A JP2016570936A JP2017506352A JP 2017506352 A JP2017506352 A JP 2017506352A JP 2016570936 A JP2016570936 A JP 2016570936A JP 2016570936 A JP2016570936 A JP 2016570936A JP 2017506352 A JP2017506352 A JP 2017506352A
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electrode
sensing
sensing electrode
reference electrode
gap
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スチュアート リンジー，
スチュアート リンジー，
ペイ パン，
ペイ パン，
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Arizona State University
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/4163—Systems checking the operation of, or calibrating, the measuring apparatus
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/48707—Physical analysis of biological material of liquid biological material by electrical means
    • G01N33/48721—Investigating individual macromolecules, e.g. by translocation through nanopores
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/301—Reference electrodes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/403—Cells and electrode assemblies
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/48—Systems using polarography, i.e. measuring changes in current under a slowly-varying voltage

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
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  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Wood Science & Technology (AREA)
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  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Nanotechnology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Biotechnology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
JP2016570936A 2014-02-25 2015-02-25 溶液と接触するナノ電子デバイスを安定化するための方法、装置およびシステム Ceased JP2017506352A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461944322P 2014-02-25 2014-02-25
US61/944,322 2014-02-25
PCT/US2015/017519 WO2015130781A1 (en) 2014-02-25 2015-02-25 Methods, apparatuses and systems for stabilizing nano-electronic devices in contact with solutions

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JP2018016278A Division JP2018066764A (ja) 2014-02-25 2018-02-01 溶液と接触するナノ電子デバイスを安定化するための方法、装置およびシステム

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JP2017506352A true JP2017506352A (ja) 2017-03-02

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JP2018016278A Pending JP2018066764A (ja) 2014-02-25 2018-02-01 溶液と接触するナノ電子デバイスを安定化するための方法、装置およびシステム

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US (2) US20170016852A1 (enExample)
JP (2) JP2017506352A (enExample)
WO (1) WO2015130781A1 (enExample)

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JP5838474B2 (ja) 2010-02-02 2016-01-06 アリゾナ ボード オブ リージェンツ オン ビハーフ オブ アリゾナ ステート ユニバーシティ ポリマーの配列を決定するための制御されたトンネルギャップデバイス
US10139417B2 (en) 2012-02-01 2018-11-27 Arizona Board Of Regents On Behalf Of Arizona State University Systems, apparatuses and methods for reading an amino acid sequence
US9274430B2 (en) 2012-10-10 2016-03-01 Arizona Board Of Regents On Behalf Of Arizona State University Systems and devices for molecule sensing and method of manufacturing thereof
EP3462167A1 (en) 2013-03-05 2019-04-03 Arizona Board of Regents on behalf of Arizona State University Translocation of a polymer through a nanopore
WO2015126963A1 (en) 2014-02-18 2015-08-27 Arizona Board Of Regents Acting For And On Behalf Of Arizona State University A three arm y-shaped bisbiotin ligand
WO2015161119A1 (en) 2014-04-16 2015-10-22 Arizona Board Of Regents Acting For And On Behalf Of Arizona State University Digital protein sensing chip and methods for detection of low concentrations of molecules
US10287257B2 (en) 2014-05-07 2019-05-14 Arizona Board Of Regents On Behalf Of Arizona State University Linker molecule for multiplex recognition by atomic force microscopy (AFM)
CN104792845A (zh) * 2014-08-07 2015-07-22 中国科学院微电子研究所 传感装置
US10422787B2 (en) 2015-12-11 2019-09-24 Arizona Board Of Regents On Behalf Of Arizona State University System and method for single molecule detection
US10379102B2 (en) 2015-12-11 2019-08-13 Arizona Board Of Regents On Behalf Of Arizona State University System and method for single molecule detection
CA3135743A1 (en) 2018-05-09 2019-11-14 Arizona Board Of Regents On Behalf Of Arizona State University Method for electronic detection and quantification of antibodies
KR20210045361A (ko) 2018-05-17 2021-04-26 레커그니션 어낼러틱스 엘엘씨 효소 활성의 직접 전기적 측정을 위한 장치, 시스템 및 방법
US12351855B2 (en) 2019-01-30 2025-07-08 Arizona Board Of Regents On Behalf Of Arizona State University Bioelectronic circuits, systems and methods for preparing and using them
CA3140279A1 (en) 2019-06-20 2020-12-24 Arizona Board Of Regents On Behalf Of Arizona State University Direct electrical readout of nucleic acid sequences
IL295828A (en) 2020-02-28 2022-10-01 Univ Arizona State Methods for biopolymer flooring
EP4136256A4 (en) 2020-04-17 2024-05-22 Arizona Board of Regents on behalf of Arizona State University ELECTRONIC SINGLE MOLECULE SEQUENCE DETECTOR AND METHOD OF USE
JP2023524079A (ja) 2020-04-30 2023-06-08 アリゾナ・ボード・オブ・リージェンツ・オン・ビハーフ・オブ・アリゾナ・ステイト・ユニバーシティー 生体高分子の配列決定のための方法
CN116018413A (zh) 2020-05-29 2023-04-25 代表亚利桑那大学的亚利桑那校董事会 具有可编程适配子的生物电子装置
EP4352244A4 (en) 2021-06-07 2025-04-16 Arizona Board of Regents on behalf of Arizona State University Methods for sequencing biopolymers

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JP2013505448A (ja) * 2009-09-18 2013-02-14 プレジデント アンド フェロウズ オブ ハーバード カレッジ 高感度分子検出及び分析を可能にする、ナノポアを有するベアの単層グラフェン膜
US20120193231A1 (en) * 2011-01-28 2012-08-02 International Business Machines Corporation Dna sequencing using multiple metal layer structure with organic coatings forming transient bonding to dna bases
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US20180224395A1 (en) 2018-08-09
JP2018066764A (ja) 2018-04-26
WO2015130781A9 (en) 2015-11-05
WO2015130781A1 (en) 2015-09-03
US20170016852A1 (en) 2017-01-19

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