JP2017190302A - Anti-fungal anti-bacterial agent, volatile space anti-fungal anti-bacterial agent, solid anti-fungal anti-bacterial material, and method for suppressing occurrence of fungi or bacteria - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide: an anti-fungal anti-bacterial agent that is a contact type or non-contact type by utilizing steam and has an anti-fungal anti-bacterial effect, has excellent smell quality and smell intensity, and has little residual smell once adhered to clothing etc.; and a method for suppressing the occurrence of fungi or bacteria by using the same.SOLUTION: Provided is an anti-fungal anti-bacterial agent characterized by containing, as an active ingredient, a monohydric alcohol solely comprising 9 carbon atoms, 1 oxygen atom and hydrogen atom and having 2 or more branched alkyl groups, and in which said active ingredient preferably is a monohydric alcohol having 2 or 3 branched methyl groups.SELECTED DRAWING: None

Description

  The present invention relates to a fungicide / antibacterial agent containing a specific alcohol as an active ingredient, and further, a volatile space fungicide / antibacterial agent used by volatilizing the fungicide / antibacterial agent in a space. The present invention relates to a solid antibacterial and antibacterial material obtained by supporting a natural space antibacterial and antibacterial agent on a carrier, and a method for suppressing generation of wrinkles or bacteria.

  Microorganisms such as sputum and fungi generally prefer high temperature and high humidity, and are easily generated in extremely narrow closed spaces such as washing machines, shoeboxes, and storage areas, as well as insulative and sealing properties such as bathrooms, toilets, kitchens, and living rooms. It often occurs in high spaces. It also frequently occurs during transport, storage, etc. of clothing, footwear, documents, fabric products and the like.

For example, if soot is generated, it may cause unpleasant odors (smell odors) and spot-like stains such as black and yellow, and damage the floors, ceilings, walls, etc. in the above places and damage the above products (articles). give. Furthermore, spores generated from sputum may float in the room and induce allergic diseases.
In this way, sputum and fungi cause many problems such as not only causing physical damage and health damage but also discomfort.

As means for preventing the growth of microorganisms such as sputum and fungi, contact-type antifungal agents and antibacterial agents are often used. However, commonly used contact antifungal agents and antibacterial agents are sprays containing sodium hypochlorite, hydroxybenzoic acid ester, benzoate, phenylphenol, phenoxyethanol, benzalkonium chloride, etc. as main components. However, it can be washed away after use if it is in the water, such as in a bathroom or toilet, but in other places, there is a concern about strong irritating odors and safety to the human body. It was.
In addition, contact antifungal agents and antibacterial agents are mainly used for cleaning, and are not intended for regular use over a certain period.
As described above, general antifungal agents and antibacterial agents cannot sufficiently impart antifungal properties and antibacterial properties unless they are brought into contact with each other, and cannot be used for a certain period of time.

  On the other hand, it is known that essential oil has antibacterial activity, and it is known to show activity even in a non-contact vapor state (Patent Documents 1 to 3). However, the space antibacterial performance and the space antibacterial performance were low.

In order to improve these, Patent Documents 4 and 5 describe antibacterial and antifungal agents that can be used in a non-contact manner in extremely narrow spaces such as a washing tub, a clog box, and a sink under storage.
However, these compounds have insufficient space barrier properties, or are larger than the above-described washing tub, shoe box, sink under storage, etc., and have a low sealing property and vaporized vapor leaks. It was difficult to sufficiently prevent the propagation of moths and fungi in Japan.

Patent Document 6 describes that a specific monovalent primary alcohol having a branched saturated aliphatic hydrocarbon group has a non-contact and antifungal effect.
However, none of these branched alcohols or primary alcohols are suitable in terms of odor quality, odor intensity, vapor pressure, etc., and the odor attached to clothing etc. remains easily. There was nothing that was fully satisfactory, such as not disappearing. In addition, the appearance as a final product is liquid, or it is effective in the form soaked in paper, cloth, etc. It is not effective in solid form and is not sufficient as an easy-to-use solid volatile space antifungal composition.

  The demand for antibacterial and antibacterial agents that exhibit antibacterial and antibacterial effects even in a space having a certain volume is increasing, and such known techniques are insufficient and there is room for further improvement.

Japanese Patent Publication No. 3-077161 JP-A-6-024952 JP 11-335219 A JP 2003-171202 A JP 2003-286114 A JP 2009-132666 A

  The present invention has been made in view of the above-mentioned background art, and the problem is excellent in antifungal and antibacterial effects, sufficiently exerting the effect even in contact or non-contact, and excellent in odor quality and odor intensity, An object of the present invention is to provide an antibacterial and antibacterial agent with little residual odor once attached to clothing and the like, and to provide a method for suppressing the generation of wrinkles and bacteria using the same.

  As a result of intensive studies to solve the above problems, the present inventor has found that a novel “alcohol having a specific chemical structure” can solve the above problems as an antifungal and antifungal agent. It came to complete.

  That is, the present invention includes a monohydric alcohol consisting of only nine carbon atoms, one oxygen atom, and hydrogen atom and having two or more branched alkyl groups as an active ingredient. It provides a fungicide.

  Moreover, this invention provides said antifungal agent which contains 3,5,5-trimethyl-1-hexanol or 2,6-dimethyl-4-heptanol as an active ingredient.

  In addition, the present invention further includes one type selected from the group consisting of (A) a chain monoterpene alcohol, (B) a cyclic monoterpene alcohol, (C) a cyclic monoterpene ketone, and (D) a cyclic sesquiterpene. The above antifungal and antibacterial agent containing the above combination compound is provided.

  The present invention also provides a volatile space fungicide and antibacterial agent as described above, which is used by volatilizing in a space.

  The present invention also provides a solid antibacterial and fungicidal material characterized in that the volatile space antibacterial and antibacterial agent is supported on a carrier.

Further, the present invention is that the above-mentioned solid antifungal antibacterial material, provides a method of suppressing the generation of fungi or bacteria, characterized in that to evaporate at room temperature in 10 ^-4 m ³ or more 200 meters ³ less space Is.

ADVANTAGE OF THE INVENTION According to this invention, the said problem and the said subject can be solved, and the antifungal agent which is excellent in sustainability and prevents generation | occurrence | production of a wrinkle and a microbe for a long period can be provided. That is, it is possible to suppress the growth of wrinkles and fungi, and to prevent stains and dirt generated on the surfaces such as wall surfaces, floor surfaces, and ceiling surfaces; objects such as clothes, shoes, and documents; It is also possible to suppress odors caused by the soot and bacteria.
For example, even if it is volatilized at room temperature in a wider space such as a washing tub, the antifungal agent of the present invention is not an unpleasant odor, the vapor pressure is suitable and the odor is not too strong, In addition, odors attached to clothes, footwear and fabric products can be easily removed if they are placed in a ventilated environment (open state) after being treated for a certain period of time.
Moreover, the antifungal agent of the present invention is not highly toxic and highly safe to the human body. On the other hand, even if it is used in a contact type or a non-contact type, it is excellent in antibacterial and antibacterial performance.

  In addition, when used in combination with a specific alcohol such as 2-ethylhexanol, terpineol, linalool, citral, or a monoterpene compound (when used in combination), both of the antifungal agents of the present invention, As a result, the odor quality, the strength of the odor, the residual odor residue, etc. are further improved. That is, the antibacterial and antibacterial performance can be exhibited even at a low mixing ratio that does not exhibit the antifungal and antibacterial performance alone, and the odor quality when used alone can be improved.

  In addition, the volatile space fungicide of the present invention exerts the fungicide effect due to the vapor generated by volatilization of the active ingredient. No need to touch antibacterial agents. In addition, the volatile space fungicide can be used at room temperature and does not need to be heated, so that its usage and usage are expanded. In addition, the effect can be accelerated by heating, ultrasonic irradiation, or the like.

  Furthermore, the volatile space antifungal agent of the present invention is supported by a support selected from the group consisting of silica, zeolite, non-woven fabric, fiber, synthetic resin, mineral, synthetic mineral, diatomaceous earth, activated clay, bentonite, black clay and activated carbon. When the solid antifungal material is supported on the body, it can be further free from unpleasant odors, sustained release, odor is not too strong, excellent in safety and easy to use.

  The volatile space antibacterial and antibacterial agent of the present invention and the solid antibacterial and antibacterial material on which the carrier is supported are an extremely narrow sealed space such as a washing machine, a shoe box, a closet, a closet, a container, etc .; bathroom, toilet It is suitable for use in closed spaces wider than the above-mentioned spaces such as kitchens, living rooms, etc., and while wrinkles such as clothes, footwear, documents, and cloth products are stored in containers and transferred. It can be used particularly preferably during storage in a container or the like, and generation of sputum and bacteria can be suitably prevented.

  Hereinafter, the present invention will be described, but the present invention is not limited to the following specific embodiments, and can be arbitrarily modified within the scope of the technical idea.

The present invention is an antifungal material comprising a monohydric alcohol composed of only 9 carbon atoms, 1 oxygen atom, and hydrogen atom and having 2 or more branched alkyl groups as an active ingredient. It is a fungicide.
The active ingredient can be used alone or in combination of two or more.

In the present specification, “fungus” includes bacteria, yeast, fungi and the like.
The antifungal and antifungal agent of the present invention has an effect on inhibition of growth (inhibition of reproduction) of moths and fungi.

<Monohydric alcohol consisting of only 9 carbon atoms, 1 oxygen atom, and hydrogen atom and having 2 or more branched alkyl groups>
Here, the above-mentioned “monohydric alcohol consisting of only nine carbon atoms, one oxygen atom, and hydrogen atom and having two or more branched alkyl groups (hereinafter,“ branched C ₉ aliphatic monohydric alcohol ”). May be abbreviated as “)” includes primary alcohols, secondary alcohols and tertiary alcohols. A primary alcohol or a secondary alcohol is preferable, and a primary alcohol is particularly preferable.
Especially when it is a primary alcohol, it is excellent in antibacterial and antibacterial performance; excellent in odor quality; odor is not too strong; adherent odor is hard to remain; when mixed with organic compounds such as fragrances, it is compared with tertiary alcohol The chemical reaction is difficult to occur; the vapor pressure at room temperature is high, so that the space antibacterial and antibacterial effects are easily exhibited.

The branched C ₉ aliphatic monohydric alcohol may have a carbon-carbon double bond or a triple bond in addition to a carbon-carbon single bond, and may have a cyclohydrocarbon ring. From the viewpoint of more exerting the effect of the present invention, it is preferable that no intercarbon double bond exists.
The number of carbon atoms in the cyclohydrocarbon ring is usually 4 to 7, but preferably 5 to 6, and 6 (that is, a cyclohexane ring) is the stability of the cyclohydrocarbon ring, It is preferable for ease of synthesis. When it has a cyclohydrocarbon ring, it has an advantage of high (prone) antifungal properties.

The branch C ₉ aliphatic monohydric alcohol having two or more branched alkyl groups. In view of the above effects, the monohydric alcohol preferably has 2 or 3 branched alkyl groups, and more preferably has 2 or 3 branched methyl groups. preferable. The carbon atom (number) of the alkyl substituent is included in “9 carbon atoms (all carbon atoms)” (number) of the branched C ₉ aliphatic monohydric alcohol.

The branched C ₉ aliphatic monohydric alcohol is preferably a monohydric alcohol having a flash point of 70 ° C. or higher. When the flash point is 70 ° C. or higher, it can be used safely and safely.

Antifungal antibacterial agent of the present invention contains a branched _{C 9} aliphatic monohydric alcohol as an active ingredient, more preferably, 3,5,5-trimethyl-1-hexanol or 2,6-dimethyl-4- It is heptanol. One kind can be used alone or two or more kinds can be used in combination.

When it is 3,5,5-trimethyl-1-hexanol or 2,6-dimethyl-4-heptanol, it is excellent in antifungal and antibacterial performance. Also, the vapor pressure and boiling point are within the preferred range and the odor is not too strong due to the chemical structure; there are few unpleasant odors and excellent odor quality; odors attached to clothing etc. are difficult to remain; early in ventilation There are advantages such as removing odors; some are relatively easily synthesized and easily available; inexpensive and economical; In addition, dihydric or higher alcohols have high viscosity and are slightly difficult to adsorb on the support.
Although isononanol described in Patent Document 6 (for example, trade name Oxocol 900 (manufactured by KH Neochem)) has 9 carbons, it is inferior in antifungal and antibacterial performance and is not included in the present invention.

The antifungal and antifungal agent of the present invention can be used in a place where microorganisms such as moths and fungi are growing or it is desired to prevent them from growing.
The small container, small boxes, packing packs, trucks, railroad cars, transfer space of the container such as when stripped at room temperature in the space, for example, about 10 ^-4 m ³ ~200m ³ such as storage space, space antifungal The antibacterial performance is specifically excellent, the odor quality is excellent, and the vapor pressure at room temperature is particularly suitable, the odor is not too strong, and the adhesion odor persistence is also excellent.
Furthermore, the synergistic effect of both compounds appears remarkably when used in combination with the combination compounds described below. That is, the antibacterial and antibacterial performance can be exhibited even at a low-concentration mixing ratio that does not exhibit the antifungal and antibacterial performance alone, and the odor quality when used alone can be further improved.

<Combination compound>
The branched C ₉ aliphatic monohydric alcohol in the antifungal agent of the present invention further contains “(A) chain monoterpene alcohol, (B) cyclic monoterpene alcohol, (C) cyclic monoterpene ketone”. And (D) one or more compounds selected from the group consisting of cyclic sesquiterpenes ”(in the present invention, the inside of“ ”may hereinafter be simply abbreviated as“ combination compound ”). The improvement of the effect is remarkable.

  Specific examples of the chain monoterpene alcohol (A) include citronellol, geraniol, nerol, linalool, dihydrolinalool, mugor, myrsenol, dihydromyrsenol, osmenol, lavandurol, and the like. It may be used in a mixture of two or more.

  (B) Specific examples of the cyclic monoterpene alcohol include isopulegol, menthol, terpineol, dihydroterpineol, terpineol-4, carveol, dihydrocarbeole, perilla alcohol, myrtenol, nobol, pinocarbeol, fenquil alcohol, borneol , Isoborneol, tweenol and the like, and these may be used alone or in combination of two or more.

  (C) Specific examples of the cyclic monoterpene ketone include carvone, menthone, isomenthone, camphor and the like, and these may be used alone or in combination of two or more. .

  (D) Specific examples of the cyclic sesquiterpene include bisabolene, caryophyllene, valencene, guayene, cedrene, kazinene, tyuopsen, and longifolene. These may be used alone or in combination of two or more. You may mix and use.

The ratio (mixing ratio) of the “branched C ₉ aliphatic monohydric alcohol” to the mass (G1) and the “combined compound” (G2) is not particularly limited, but the total mass (G = G1 + G2) of the two On the other hand, G1 is preferably 20% by mass to 100% by mass, more preferably 30% by mass to 90% by mass, particularly preferably 35% by mass to 85% by mass, and further preferably 40% by mass to 80% by mass. preferable.
If it is the said range, the effect mentioned above and the following (combined use) will be exhibited suitably.

Since many (A) chain monoterpene alcohols, (B) cyclic monoterpene alcohols, (C) cyclic monoterpene ketones and (D) cyclic sesquiterpenes have fragrance, further improve the odor quality of the C ₉ aliphatic monohydric alcohol ". Further, since the monoterpene alcohol itself has an antifungal and antibacterial effect, the antifungal and antibacterial performance can be exhibited even by mixing at a low concentration, which alone does not show the antifungal and antibacterial performance.

  The antifungal and antibacterial agent can exert antifungal and antibacterial performance by directly spraying or coating the antifungal / antifungal agent on a place where it is desired to suppress the growth of the fungus or fungus and directly contacting the fungus or fungus. Moreover, as shown below, antifungal and antibacterial performance can be exhibited by the vapor of the active ingredient that is carried on the carrier and volatilized.

<Volatile space antifungal agent>
The volatile space antifungal agent of the present invention is the above antifungal agent, and is characterized by being volatilized in a space.

  The volatile space antifungal agent of the present invention can be used, for example, by a method of supporting it on a carrier described later.

<Solid antifungal material>
The volatilization rate of the volatile space fungicide of the present invention can be adjusted by the configuration of the opening area of the packaging material, container, etc., and can be dissolved in a solvent or gel, or kneaded with a resin or the like. Or by microencapsulation to adjust the release.
The gelling agent is not particularly limited, and examples thereof include water-soluble organic polymers such as polyvinyl alcohol, polyethylene glycol, polyvinyl pyrrolidone, alginic acid, cellulose, starch, and derivatives or salts thereof; vinyl acetate resin Examples include emulsions such as emulsions, acrylic emulsions, rubber latexes; natural products derived from animals and plants such as carrageenan, agar, gelatin, and pectin, and algae.

  The volatile space antibacterial agent of the present invention described above is particularly preferably used as a solid antibacterial / antibacterial material by supporting it on a carrier for easy handling and sustained release.

The above “branched C ₉ aliphatic monohydric alcohol” and the above “combination compound” are liquids not only at room temperature (15 ° C. to 25 ° C.) but also at the intended use temperature (−20 ° C. to 40 ° C.). the solid ", it refers to a solid form, those liquid into another solid (the above-mentioned present invention," branched C ₉ aliphatic monohydric alcohol ") is deposited as a whole appearance of the Bokabibokin material and or is steeped or not, squeeze, easy ones of the liquid-like and an operation such as centrifugal separation (the above-mentioned present invention, "branched C ₉ aliphatic monohydric alcohol") is ready to be separated is removed.
Examples of the “separate body” include paper such as filter paper; cloth such as nonwoven fabric and woven fabric; cotton such as natural cotton and chemical cotton; sponge such as polyurethane sponge; glass fiber (aggregate); pumice stone, core rod, and porous membrane Such as “a lump having a size of 0.5 cm ³ or more, which is roughened or has a space for increasing the surface area of bubbles or the like inside” is excluded.

In the case of a branched C ₉ aliphatic monohydric alcohol, the vapor pressure is often high, the evaporation rate is too fast, and the period of use is shortened in the case where the other solid is simply attached or simply soaked. There are cases where antibacterial and antibacterial components adhere to the body when directly touching the skin.

Examples of the support to be used as a solid antifungal material include silica, zeolite, non-woven fabric, fiber, synthetic resin, mineral, synthetic mineral, diatomaceous earth, activated clay, bentonite, black clay and activated carbon. It is done.
These have a number average particle diameter of preferably 0.1 μm to 10 mm, more preferably 0.3 μm to 3 mm, and particularly preferably 1 μm to 1 mm.

The solid antifungal material of the present invention has “branched C ₉ aliphatic monohydric alcohol” and / or “combination compound” supported in less than the amount of oil absorption of the powder as a whole, The form which maintains solid state without fluidity, such as a lump shape, is preferable.
The solid antibacterial and antifungal material of the present invention is formed by supporting the above liquid on a support. Here, “supported” means chemical / physical adsorption, adsorption by van der Waals force. And the like.

  Preferable supports include silica such as silica gel; zeolite, diatomaceous earth, activated carbon, fiber, mineral, synthetic mineral and the like.

The ratio of the total mass (G) of the “branched C ₉ aliphatic monohydric alcohol” and the “combination compound” to the mass (H) of the carrier is not particularly limited, but is 0.5 as G / (G + H). % By mass to 80% by mass is preferable, 10% by mass to 70% by mass is more preferable, and 20% by mass to 50% by mass is particularly preferable. When G is too large, or the separation of liquid came out shall not be carried, there is a case where the branch C ₉ aliphatic monohydric alcohol or combination compound or wasted. On the other hand, when G is too small, carrier It may be difficult to use only the weight of the.

Since the solid antifungal material of the present invention has the “branched C ₉ aliphatic monohydric alcohol” and / or “combination compound” supported on the support, it becomes a sustained release property, and the odor is not too strong. Odor is not attached, it is excellent in safety and easy to use.
The volatile space fungicide of the present invention can extend the use period by 2 to 100 times by using it as a solid fungicide and antibacterial material than when it is used wet with liquid or cloth. .

  The volatile space fungicide or solid fungicide of the present invention does not exclude the combined use with the clathrate compound, but the above effect can be exhibited without using the clathrate compound. Moreover, although the controlled release by use of a permeable film etc. is not excluded, the said effect can be exhibited even if it does not use them.

<Other ingredients>
In the volatile space antibacterial and antibacterial agent of the present invention, if necessary, various solvents generally added in addition to the above components, as long as the effects of the present invention are not impaired. It may contain other components such as oils, inorganic salts, amino acids, organic acid salts, pH adjusters, antioxidants, antiseptics, bactericides / antibacterial agents, deodorants, fragrances, dyes, UV absorbers, and water. it can.

<Usage pattern>
The volatile space antibacterial and antibacterial agent of the present invention, and the solid antifungal and antibacterial material on which the carrier is supported can also be used in containers such as bottles and boxes, and can be used in washing machines, shoe boxes and closets. It can be suitably used in a closed space (B), such as a bathroom, a toilet, a kitchen, a living room, etc., and a clothing, footwear, documents, cloth, etc. It can be used particularly preferably in the space (C) during storage of articles such as products in containers, etc. or during storage in containers, etc. Can be prevented.

<Method for suppressing generation of sputum or bacteria>
Another aspect of the present invention is characterized in that the volatile space antifungal antibacterial agent or solid antifungal antibacterial material, is vaporized at room temperature in 10 ^-4 m ³ or more 200 meters ³ less space fungus Or it is the method of suppressing generation | occurrence | production of a microbe.
The use in the space (B) or the space (C) described above is preferable.
^{Further, 10} is preferably used in -4 ^{m 3} or more 200 meters ³ less space, it is more preferably used in the 0.3 m ³ or more 200 meters ³ less space, use at 1 m ³ or more 100 m ³ or less space is particularly preferred . Use in a space in the above volume range is useful for confirming and comparing the superiority of volatile antibacterial and antibacterial effects with other volatile space antibacterial and antibacterial agents, This is particularly preferable from the viewpoint that an effect can be expected.

  After using the volatile space fungicide or solid fungicide of the present invention, the object to be treated is opened from a sealed / closed space such as the space (A), (B), or (C). It is preferable to allow a certain period of time to elapse or to move the space (inner wall or the like) to an open state.

  Hereinafter, the present invention will be described more specifically with reference to examples. However, the present invention is not limited to these examples as long as the gist thereof is not exceeded.

Evaluation example <Evaluation method of space fender resistance>
A sealed container (lid: polyethylene, main body: polypropylene) having a length of 18 cm, a width of 13 cm, and a height of 6 cm was prepared.
A 20 mm × 20 mm × 6 mm thick nonwoven fabric was adhered to the back of the lid, and 100 μL of the sample was applied with a micropipette.

  The cultured black persimmon (Aspergillus niger) is applied to a potato dextrose agar medium (Eiken Chemical Co., Ltd.) in a petri dish with a diameter of 9 cm using a platinum loop, and the petri dish is applied to the bottom of a sealed container. Sealed with a lid.

  The airtight container was allowed to stand for 72 hours in a thermostat set at 30 ° C., and then the presence or absence of black candy was visually confirmed from above the petri dish, and judged according to the following criteria.

<Criteria for determining spatial fenders>
◎: The petri dish is not black at all ○: Slightly good control force is shown, but slight growth of cocoon is observed △: Growth of cocoon is recognized at 1/5 surface area ×: 黴 is observed at 1/2 surface area Admit to nurturing XX: Acupuncture grows across the petri dish

<Evaluation method for contact resistance>
The filter paper was cut to a diameter of 12 mm and 30 μL of the sample was applied.
The cultured black persimmon (Aspergillus niger) was applied to a potato dextrose agar medium in a petri dish having a diameter of 9 cm using a platinum loop, and a filter paper coated with the sample thereon was placed. A petri dish was placed in an airtight container that was also used for the space fouling resistance test, and the lid was closed and sealed. After leaving still for 72 hours with a thermostat set at 30 ° C., the growth status of black panther was visually confirmed and evaluated according to the following criteria.

<Criteria for contact resistance>
◎: The whole petri dish is not black at all ○: There is a stop band (area where bacteria do not grow) around the filter paper, its width is 2 mm or more △: There is a stop band around the filter paper, but its width is less than 2 mm ×: No stop band

<Method for evaluating antibacterial properties>
The filter paper was cut to a diameter of 12 mm and 30 μL of the sample was applied.
The cultured Escherichia coli was applied to a normal agar medium (Eiken Chemical Co., Ltd.) in a petri dish having a diameter of 9 cm using a platinum loop, and a filter paper coated with the sample thereon was placed. The petri dish was covered and allowed to stand for 72 hours in a thermostat set at 30 ° C., and then the growth of E. coli was visually confirmed and evaluated according to the following criteria.

<Criteria for antibacterial properties>
○: There is a stop band around the filter paper, and the width is 2 mm or more. Δ: There is a stop band around the filter paper, but the width is less than 2 mm. X: There is no stop band.

<Odor quality evaluation method>
A 10 mL sample was placed in a 60 mL light-shielding bottle, and the liquid temperature was adjusted to 25 ° C. The nose was brought close to the bottle mouth and smelled, and the determination was made according to the following criteria.

<Criteria for odor quality>
◎: Smell that does not matter at all, no problem in actual use conditions ○: Smell that is not bothered or uncomfortable, no problem in actual use conditions △: Some people feel uncomfortable, but use There is no problem depending on the conditions. ×: Unpleasant odor, even under actual use conditions. XX: Extremely unpleasant or irritating odor, even under actual use conditions.

<Odor intensity evaluation method>
The sealed container used in the space antifungal evaluation test was opened and smelled, and judged according to the following criteria.

<Judgment criteria for odor intensity>
◎: Little or no odor ○: Easy odor △: Strong odor ×: Strong odor

<Method for evaluating adhesion odor persistence>
A conical beaker containing 1 mL of a sample and one Kim Towel (registered trademark, manufactured by Nippon Paper Crecia Co., Ltd.) were placed in a sealable container having a volume of 20 L and allowed to stand at room temperature for 3 days. The smell of the removed Kim towel was sniffed and judged according to the following criteria.

<Criteria for sticking odor residue>
◎: No odor attached ○: Odor attached, but no odor when left in open space for 3 hours △: Odor is attached, but left in open space for 3 hours If it is done, the odor will be weak. X: The odor will be attached, and a strong odor will remain even if left in an open space for 3 hours.

<Flammability criteria>
○: Flash point is 70 ° C or higher ×: Flash point is lower than 70 ° C

<Toxicological evaluation method>
A mixture or a single compound was evaluated by a classification method for chemical substances based on JIS Z7252 GHS. For the hazard information of raw materials, data from the National Institute of Technology and Evaluation (NITE) was used. When not listed in NITE, MSDS information issued by a reagent company was used.

<Harmful criteria>
○: As a result of classification based on GHS, there is no warning word △: As a result of classification based on GHS, the warning word is a warning ×: As a result of classification based on GHS, the warning word is dangerous Is

<Criteria for comprehensive evaluation>
A: Excellent as an antibacterial and antibacterial agent (no space or no contact resistance, no antibacterial property, no △ or ◯, or ◎ or ○ in other items; 2 or less)
B: Suitable as an antibacterial / antibacterial agent (no spatial anti-bacterial property, contact anti-bacterial property, no anti-bacterial property, and the number of Δ is 3 or less)
C: Can be used as an antibacterial and antibacterial agent, but is inferior (poor space antibacterial property, contact antibacterial property, antibacterial property is not X, and other items have X or the number of Δ is 4 More)
D: It is inferior and cannot be used as a fungicide and antibacterial agent (there is × in any one of the space fungicide, contact fungicide and fungicide)

Example 1
The sample whose composition is shown in Table 1 was evaluated and evaluated by the above evaluation method. The evaluation results are shown in Table 2.

From the results of Table 2, any sample branched C ₉ Sample No. 1 and 2 is an aliphatic monohydric alcohol, was space antifungal, contact antifungal and antibacterial properties "○" or higher. Other evaluation items did not have “x”, and “Δ” was 2 or less, and the comprehensive evaluation was excellent as “A”.

On the other hand, the samples Nos. 11 and 12 each having a branched alcohol having 8 carbon atoms have a contact resistance and fungicide property of “△”, a flammability of “x”, and a comprehensive evaluation of “C”. "Met.
Samples Nos. 13 and 14, which are straight-chain alcohols with 9 carbon atoms, have a spatial antifungal property and residual odor residue of “Δ” or less, a hazard of “Δ”, and a comprehensive evaluation of “ C "or less.
Sample No. 15, which has 9 carbon atoms and 0 to 1 branched methyl groups, has a spatial antifungal property and antibacterial property of “△”, and an attached odor residual property of “×”, and is comprehensively evaluated. Was “C”.
The sample of Sample No. 16 having 10 carbon atoms and 2 branched methyl groups had a space anti-fouling property and an attached odor residual property of “x”, and the overall evaluation was “D”.

  The volatile space antifungal agent of the present invention and the solid volatile space antifungal composition in which the volatile space antifungal agent is supported on a carrier are used in a non-contact manner, have an excellent space antifungal effect, high safety, and odor quality. Because it is excellent in odor intensity, sticking odor persistence, etc., it is suitable not only for household use but also for business use such as transportation and storage. It is widely used in the field.

Claims (9)

  An antifungal and antibacterial agent comprising, as an active ingredient, a monohydric alcohol consisting of only nine carbon atoms, one oxygen atom, and a hydrogen atom and having two or more branched alkyl groups.   The antifungal and antifungal agent according to claim 1, which is a monohydric alcohol having 2 or 3 branched methyl groups.   The antifungal and antifungal agent according to claim 1 or 2, comprising a monohydric alcohol having a flash point of 70 ° C or higher as an active ingredient.   The antifungal agent according to any one of claims 1 to 3, comprising 3,5,5-trimethyl-1-hexanol or 2,6-dimethyl-4-heptanol as an active ingredient.   Furthermore, it contains one or more combination compounds selected from the group consisting of (A) chain monoterpene alcohol, (B) cyclic monoterpene alcohol, (C) cyclic monoterpene ketone, and (D) cyclic sesquiterpene The antifungal and antifungal agent according to any one of claims 1 to 4.   6. The antifungal / antifungal agent according to any one of claims 1 to 5, which is used after being volatilized in a space.   A solid antifungal material having the volatile space antifungal agent according to claim 6 supported on a carrier.   The solid according to claim 7, wherein the carrier is a carrier selected from the group consisting of silica, zeolite, nonwoven fabric, fiber, synthetic resin, mineral, synthetic mineral, diatomaceous earth, activated clay, bentonite, black clay, and activated carbon. Antifungal material. The solid antifungal antibacterial material according to claim 7 or claim 8, ^10-4 method of suppressing the mold or development of fungi, characterized in that to evaporate at room temperature in m ³ or more 200 meters ³ less space.