JP5185689B2 - Non-contact fungicide composition - Google Patents

Description

  The present invention relates to a non-contact type fungicide composition and a package thereof.

  Generally, clothes are used in a cycle of “wear → washing → storage” after purchase, but it is important to protect (care) from troubles such as mold and odor that are anxious during storage. . Conventional antifungal agents are powders or crystals such as methyl paraoxybenzoate, ethyl paraoxybenzoate, benzoic acid, sodium benzoate, orthophenylphenol, or liquids such as benzalkonium chloride, both of which are protected. If the mold is not brought into contact with the mold, the mold prevention performance cannot be sufficiently provided.

It is also important to maintain the effect for a long period of time, and techniques relating to the sustained release of fragrances and biocides have been disclosed so far. Patent Document 1 discloses a technique related to a silicate ester mixture. Patent Document 2 discloses a technique related to a preparation absorbed on the surface of a base material. Patent Document 3 discloses a technique related to an aromatic substance precursor compound. Patent Documents 4 and 5 disclose techniques related to aroma-releasing non-volatile polymer siloxane.
Special table 2003-526644 Special table 2007-502918 JP-A-10-330382 JP 2000-119394 A JP 2000-119395 A

  The techniques of Patent Documents 1 and 2 describe compounds that release perfume alcohol and biocidal alcohol by hydrolysis, and are provided as a perfume for detergents and detergent compositions, or skin care and hair care preparations. The biocidal alcohol here is only described as being advantageous for exhibiting the preservative effect of the composition, and does not describe antifungal performance in a non-contact state. Although the technique of Patent Document 3 describes a compound that releases an aromatic substance when it comes into contact with the skin or in the presence of lipase, the antifungal effect without contact is insufficient. Moreover, in the technique of patent document 4 and 5, although the fragrance | flavor releasing siloxane which discharge | releases a fragrance at the time of a hydrolysis is described, neither of them is sufficient in anti-mold property.

  Accordingly, an object of the present invention is to provide a non-contact type anti-fungal agent composition that can continue to exhibit excellent anti-mold performance for a long period of time without being brought into direct contact with the object to be protected.

  The present inventors have found that a composition containing a silicate compound of a specific alcohol can exhibit antifungal performance for a long period of time without being brought into direct contact with the article to be protected.

That is, the present invention relates to a non-contact type fungicide composition containing the following component (a), a non-contact type fungicide composition further containing the following component (b), and these non-contact type fungicide. An antifungal composition package comprising the composition housed in a container is provided.
(A) Component: at least one selected from compounds represented by the general formula (1)

[Wherein, X is —OH, —R ¹ or —OR ² , R ¹ is a hydrocarbon group having 1 to 22 carbon atoms, —OR ² is 6 to 15 carbon atoms, and has a boiling point of 150 to 280. C is a residue of an alcohol having a log P value of 1 to 4, Y is X or —OSi (X) ₃ , and n is a number from 0 to 15 indicating an average value. A plurality of X and Y may be the same or different, but have at least one —OR ^{2 in} one molecule. ]
(B) Component: At least one selected from the compound represented by the general formula (2) R ³ —O (AO) _m H (2)
[In the formula, R ³ is an alkyl group having 7 to 11 carbon atoms, A is an alkylene group having 2 to 3 carbon atoms, m is a number of 1 to 3 indicating an average added mole number, and m A's may be the same. It may be different. ]

  The non-contact type anti-fungal agent composition and the package thereof of the present invention can continue to exhibit an excellent anti-fungal function for a long period of time without contacting the anti-mold product.

[(A) component]
The component (a) of the present invention is at least one selected from the compounds represented by the general formula (1). In General Formula (1), X is —OH, —R ¹ or —OR ² , Y is X or —OSi (X) ₃ , and the compound represented by General Formula (1) is — has at least one OR ^2. Moreover, n is the number of 0-15 which shows an average value, the number of 0-10 is preferable, and the number of 1-8 is more preferable.

R ¹ is a hydrocarbon group having 1 to 22 carbon atoms, preferably a linear or branched alkyl group or alkenyl group having 1 to 22 carbon atoms, having 1 to 20 carbon atoms, and more preferably an alkyl group having 1 to 18 carbon atoms. Or an alkenyl group is more preferable.

—OR ² is an alcohol residue having 6 to 15 carbon atoms, a boiling point of 150 to 280 ° C., and a log P value of 1 to 4. The boiling point of such alcohol is preferably 170 to 260 ° C. The log P value is preferably 1.0 to 3.5.

  Here, the “log P value” is a logarithmic value of the 1-octanol / water partition coefficient of the compound, and in the partition equilibrium when the compound is dissolved as a solute in the two-liquid solvent system of 1-octanol and water. , Means the ratio of the equilibrium concentration of the solute in each solvent and is generally indicated in the form of log “log P” with respect to the base 10. That is, the log P value is an index of lipophilicity (hydrophobicity). The larger the value, the more hydrophobic, and the smaller the value, the more hydrophilic.

  For the log P value, see, for example, Daylight Chemical Information Systems, Inc. A logP value published in a database available from (Daylight CIS) or the like can be referred to as an actual measurement value. Further, when there is no actual measurement value, it can be calculated by a program “CLOGP” (Daylight CIS) or the like, and among them, calculation by the program “CLOGP” is preferable because of high reliability.

  In the program “CLOGP”, the value of “calculated logP (ClogP)” calculated by the Hansch, Leo fragment approach is output together with the measured value of logP, if any. The fragment approach is based on the chemical structure of the compound and takes into account the number of atoms and the type of chemical bond (A. Leo, Comprehensive Medicinal Chemistry, Vol. 4, C. Hansch, P. G. Sammens, J. et al. B. Taylor and CA A. Ramsden, Eds., P. 295, Pergamon Press, 1990). Since this ClogP value is currently the most common and reliable estimate, it is preferable to use the ClogP value instead when there is no measured value of logP when selecting a compound. In the present invention, either an actual measured value of logP or a ClogP value calculated by the program “CLOGP” may be used. However, when there is an actual measured value, it is preferable to use the actual measured value.

The alcohol constituting the -OR ² (R ² OH), aliphatic alcohols, straight-chain or branched 6-11 carbon atoms, terpene alcohols, alicyclic alcohols having 7 to 15 carbon atoms, 7 carbon atoms Alcohols selected from 15 arylalkyl alcohols or alkylaryl alcohols are preferred.

  The linear or branched aliphatic alcohol having 6 to 11 carbon atoms is preferably a linear or branched aliphatic alcohol having 7 to 11 carbon atoms, and more preferably 8 to 11 carbon atoms. Specific examples of the aliphatic alcohol include hexanol, isohexanol, 2-hexanol, 3-hexanol, heptanol, isoheptanol, 2-heptanol, 3-heptanol, octanol, isooctanol, 2-octanol, 3-octanol, and nonanol. , Isononanol, 2-nonanol, 3-nonanol, decanol, isodecanol, 2-decanol, 3-decanol, undecanol, isoundecanol, 2-undecanol, 3-undecanol, 2-methylpentanol, 2-methylhexanol, 2 -Methylheptanol, 2-methyloctanol, 2-methylnonanol, 2-methyldecanol, 2-ethylbutanol, 2-ethylpentanol, 2-ethylhexanol, 2-ethylheptanol 2-ethyloctanol, 2-ethylnonanol, cis-3-hexenol, 1-octen-3-ol, dimethylol, decenol, 2,6-nonadienol, 10-undecenol, trans-2-cis-6-nonadienol, etc. Can be mentioned.

  Among these, from the viewpoint of fungicidal effect, heptanol, isoheptanol, octanol, isooctanol, nonanol, isononanol, decanol, isodecanol, undecanol, isoundecanol, 2-methylhexanol, 2-methylheptanol, 2 -Methyloctanol, 2-methylnonanol, 2-methyldecanol, 2-ethylpentanol, 2-ethylhexanol, 2-ethylheptanol, 2-ethyloctanol, 2-ethylnonanol, 1-octene-3- All, decenol and 2,6-nonadienol are preferred, and octanol, isooctanol, nonanol, isononanol, decanol, isodecanol, undecanol, isoundecanol, 2-methylheptanol, 2-methylol Pentanol, 2-methyl nonanol, 2-methyl-octadecanol, 2-ethylhexanol, 2-ethyl heptanol, 2-ethyl octanol, 2-ethyl nonanol, decenol, 2,6 nonadienol is more preferable.

  Specific examples of the terpene alcohol include linalool, geraniol, nerol, citronellol, myrcenol, lavandulol, tetrahydrogeraniol, tetrahydrolinalol, hydroxycitronellol, dihydromyrcenol, α-terpineol, tarpinene-4-ol, isopulegol, and the like. Can be mentioned.

  Among these, from the viewpoint of fungicidal performance, linalool, geraniol, nerol, citronellol, α-terpineol, terpinen-4-ol, and isopulegol are preferable, and geraniol, nerol, citronellol, α-terpineol, and terpinene-4-ol are preferable. More preferred.

  The alicyclic alcohol having 7 to 15 carbon atoms is preferably an alicyclic alcohol having 8 to 13 carbon atoms and further 9 to 11 carbon atoms. Specific examples of the alicyclic alcohol include 2,4-dimethyl-3-cyclohexene-1-methanol (manufactured by IFF: Floralol), 4-isopropylcyclohexanol (manufactured by Givaudan-Roure: Forrussia), and 4-isopropyl. Cyclohexanemethanol (manufactured by Firmenich: Mayor), 1- (4-isopropylcyclohexyl) -ethanol (manufactured by H & R: mugetanol), 2,2-dimethyl-3- (3-methylphenyl) -propanol (manufactured by Wacker: MA Gentol), ambrinor and the like.

  Among these, from the viewpoint of mold prevention performance, 2,4-dimethyl-3-cyclohexene-1-methanol (manufactured by IFF: Floralol), 4-isopropylcyclohexanol (manufactured by Givaudan-Roure: Forrussia), 4 -Isopropylcyclohexanemethanol (manufactured by Firmenich: Mayor), 1- (4-isopropylcyclohexyl) -ethanol (manufactured by H & R: mugetanol), 2,2-dimethyl-3- (3-methylphenyl) -propanol (manufactured by Wacker) : Majantor) is preferred, and Floralol, Forrussia and Mayor are more preferred.

  The arylalkyl alcohol or alkylaryl alcohol having 7 to 15 carbon atoms is preferably an arylalkyl alcohol or alkylaryl alcohol having 7 to 13 carbon atoms and further 7 to 11 carbon atoms. Specific examples thereof include benzyl alcohol, phenylethyl alcohol, phenoxyethyl alcohol, phenylpropyl alcohol, phenylhexanol, carvacrol, eugenol, isoeugenol and the like.

  Among these, benzyl alcohol, phenylethyl alcohol, phenylpropyl alcohol, carvacrol, and eugenol are preferable from the viewpoint of fungicidal performance, and benzyl alcohol, phenylethyl alcohol, carvacrol, and eugenol are more preferable.

  (A) component of this invention can be used 1 type or in mixture of 2 or more types.

[Component (b)]
The component (b) of the present invention is at least one selected from the compounds represented by the general formula (2).

In the general formula (2), R ³ is an alkyl group having 7 to 11 carbon atoms, and the alkyl group may be linear or branched. Specific examples of R ³ include groups such as heptyl, octyl, 2-ethylhexyl, nonyl, decyl, isodecyl and undecyl. A is an alkylene group having 2 to 3 carbon atoms, and the alkylene group may be linear or branched, and m A may be the same or different. Specific examples of A include a propylene group (propane-1,2-diyl group), an ethylene group, and a trimethylene group, and a propylene group and an ethylene group are preferable. m is a number from 1 to 3 indicating the average number of moles added, and a number from 1 to 2 is preferred.

As the compound represented by the general formula (2), R ³ is an alkyl group having 7 to 11 carbon atoms, A is a propylene group, m is a number having 1 to 2, and R ³ is 7 to 11 carbon atoms. A compound in which A is an ethylene group and m is a number of 1 to 2 is preferable.

  Specific examples of the component (b) include, for example, propylene glycol monoalkyl (alkyl group having 7 to 11 carbon atoms) ether, dipropylene glycol monoalkyl (alkyl group having 7 to 11 carbon atoms) ether, tripropylene glycol monoalkyl. (Alkyl group having 7 to 11 carbon atoms) ether, ethylene glycol monoalkyl (alkyl group having 7 to 11 carbon atoms) ether, diethylene glycol monoalkyl (alkyl group having 7 to 11 carbon atoms) ether, triethylene glycol monoalkyl (alkyl Group having 6 to 11 carbon atoms, trimethylene glycol monoalkyl (alkyl group having 7 to 11 carbon atoms) ether, di (trimethylene glycol) monoalkyl (alkyl group having 7 to 11 carbon atoms) ether, tri (tri Methylene glycol) monoal Le (number of carbon atoms in the alkyl group from 7 to 11) ether.

  Among these, from the viewpoint of fungicidal effect, propylene glycol monoalkyl (alkyl group having 7 to 11 carbon atoms) ether, dipropylene glycol monoalkyl (alkyl group having 7 to 11 carbon atoms) ether, ethylene glycol monoalkyl ( Alkyl group carbon number 7-11) ether and diethylene glycol monoalkyl (alkyl group carbon number 7-11) ether are preferred.

  Further, from the viewpoint of low odor, dipropylene glycol monoheptyl ether, propylene glycol monooctyl ether, dipropylene glycol monooctyl ether, propylene glycol mono-2-ethylhexyl ether, dipropylene glycol mono-2-ethylhexyl ether, propylene glycol Monononyl ether, dipropylene glycol monononyl ether, propylene glycol monodecyl ether, dipropylene glycol monodecyl ether, propylene glycol monoisodecyl ether, dipropylene glycol monoisodecyl ether, propylene glycol monoundecyl ether, dipropylene glycol mono Undecyl ether, diethylene glycol monoheptyl ether, ethylene glycol Dimonooctyl ether, diethylene glycol monooctyl ether, ethylene glycol mono-2-ethylhexyl ether, diethylene glycol mono-2-ethylhexyl ether, ethylene glycol monononyl ether, diethylene glycol monononyl ether, ethylene glycol monodecyl ether, diethylene glycol monodecyl ether, ethylene glycol Monoisodecyl ether, diethylene glycol monoisodecyl ether, ethylene glycol monoundecyl ether, and diethylene glycol monoundecyl ether are more preferable.

  (B) component of this invention can be used 1 type or in mixture of 2 or more types.

[Non-contact mold prevention composition and its package]
The non-contact fungicide composition of the present invention contains the component (a) as a main component, and the form thereof may be any form such as gel, powder, granule, and liquid.

  Although content of (a) component in the non-contact-type antifungal agent composition of this invention can be suitably adjusted with the kind and usage form, 0.1 mass% or more is preferable and 0.1-70 is preferable. % By mass is more preferable, 0.1 to 60% by mass is further preferable, and 1 to 50% by mass is particularly preferable.

  Moreover, it is preferable that the composition of this invention contains (b) component further. Although content of (b) component in the composition of this invention can be suitably adjusted with the kind and usage form, 0.1 mass% or more is preferable normally, and 0.1-70 mass% is more preferable. 0.1-60 mass% is still more preferable, and 1-50 mass% is especially preferable.

  The blending ratio of the component (a) and the component (b) in the composition of the present invention is such that (a) / (b) (mass ratio) is 100 / 1/1/100 is preferable, 50/1 to 1/50 is more preferable, and 20/1 to 1/50 is still more preferable.

  When the non-contact type fungicide composition of the present invention is gelled, it is common to use a gelling agent. The gelling agent is not particularly limited. For example, polyvinyl alcohol, polyethylene glycol, polyvinyl pyrrolidone, alginic acid, cellulose, starch, etc., or derivatives or salts thereof formed from water-soluble organic polymers such as vinyl acetate Resin emulsions, synthetic resin emulsions such as vinyl acetate and vinyl chloride copolymer resin emulsions, water soluble emulsions such as rubber latex, carrageenan, agar, gelatin, pectin and other animals, plants, algae, and microorganisms Examples thereof include gelling agents derived from natural products to be extracted.

  Although content of (a) component in a gel-like non-contact-type antifungal agent composition can be suitably adjusted with the kind and usage form, 0.1-60 mass% is preferable normally, and 1-50 The mass% is more preferable.

  In order to disperse and emulsify component (a) in the gel-like non-contact type fungicide composition, it is preferable to use a surfactant. There is no restriction | limiting in particular as surfactant, At least 1 sort (s) chosen from a nonionic surfactant, a cationic surfactant, an anionic surfactant, and an amphoteric surfactant can be used. .

  Nonionic surfactants include polyoxyalkylene alkyl or alkenyl ether, polyoxyalkylene alkyl phenyl ether, polyoxyalkylene fatty acid ester, polyoxyalkylene sorbitan fatty acid ester or polyoxyalkylene glycerin fatty acid ester, polyoxyalkylene sorbit fatty acid ester , Polyoxyalkylene castor oil or hydrogenated castor oil, alkyl or alkenyl diethanolamide, alkylamine or alkyldimethylamine, alkenylamine or alkenyldimethylamine, polyoxyalkylenealkyl or alkenylamine and the like.

  Examples of the cationic surfactant include primary amine salts, secondary amine salts, tertiary amine salts, and quaternary ammonium salts.

  Anionic surfactants include alkyl benzene sulfonates, alkyl sulfates or alkenyl sulfates, olefin sulfonates, alkane sulfonates, salts of alkyl polyhydric alcohol ether sulfonates such as alkyl glyceryl ether sulfonates, Examples include higher fatty acid salts, alkyl or alkenyl ether sulfates, alkyl or alkenyl ether carboxylates, and the like.

  Amphoteric surfactants include alkyl or alkenylamine oxide, amidopropylamine oxide (obtained by reacting amide compound of lauric acid and dimethylaminopropylamine with hydrogen peroxide, etc.), dimethyllaurylamine oxide, dimethylamino Examples include betaine acetate, imidazolinium betaine, fatty acid amidopropyldimethylaminoacetic acid betaine, N-acylamino acid or a salt thereof, and N-acylmethyltaurate.

  When the non-contact fungicide composition of the present invention is powdered or granular, as a powder or granular carrier, silica gel, zeolite, calcium silicate, diatomaceous earth, alumina, allophane, vermiculite, perlite, shirasu balloon, sepiolite, Inorganic porous carriers such as kaolin, hydrotalcite, talc, snow tech and bentonite, and organic porous carriers such as activated carbon, pulp, fiber material and synthetic resin can be used.

  The content of the component (a) in the powdery or granular non-contact fungicide composition can be appropriately adjusted depending on the type and use form, but is usually preferably 0.1 to 70% by mass. -60 mass% is more preferable.

  When the non-contact type fungicide composition of the present invention is made liquid, the above-mentioned surfactant or a solvent such as alcohol can be used as a solubilizer. The liquid composition can be used by a conventionally known method such as a method of soaking in a core rod, filter paper, nonwoven fabric or the like and volatilizing using a permeable membrane.

  Although content of (a) component in a liquid non-contact-type antifungal agent composition can be suitably adjusted with the kind and usage pattern, 0.1-40 mass% is preferable normally, and 1-30 mass. % Is more preferable.

  The non-contact type anti-fungal agent composition of the present invention can be added to various solvents, oils, sodium sulfate, sodium sulfate, N, N, Other components such as a salt such as N-trimethylglycine, a pH adjuster, an antioxidant, an antiseptic, a bactericidal / antibacterial agent, a deodorant, a fragrance, a dye, and an ultraviolet absorber can be contained.

  The non-contact type fungicide composition of the present invention can be provided as a fungicide composition package in a container. The non-contact type fungicide composition of the present invention is directly or dissolved in a volatile solvent, and remains in a liquid state or is stored in a gas-permeable, air-permeable container in the above-described gel, powder or granular form. . Examples of the breathable container include a bag-like product made of a laminate composed of a breathable thermoplastic resin on the inner surface and a breathable support on the outer surface. For example, a nonwoven fabric is used as the breathable support. And a bag made of laminated paper made by laminating a breathable thermoplastic resin film such as a polyethylene film.

  The non-contact fungicide composition of the present invention and its package can be installed in, for example, a closet, a closet, a shoe box, etc. to prevent the occurrence of mold on clothes, shoes, wall surfaces, floor surfaces, etc. In particular, it is suitable for use in a space storing clothes such as a closet and a closet to prevent generation of mold on the clothes.

Synthesis example 1
In a 200 mL four-necked flask, add 145.92 g of tetraethoxysilane, 0.48 g of potassium hydroxide, and 0.8 mL of ion exchange water, and react for about 37 hours at 120 to 125 ° C. and 33 kPa to 101 kPa (normal pressure) under a nitrogen stream. Went. During this time, 0.8 mL of ion-exchanged water was added. After the reaction, the reaction was further continued at 33 kPa for 2 hours, followed by cooling and filtration to obtain 134.58 g of an ethoxysilane condensate as a pale yellow liquid.

Subsequently, 25.00 g of the above tetraethoxysilane condensate and 62.93 g (0.41 mol) of geraniol (boiling point 230 ° C., log P value 2.77) were added to a 100 mL four-necked flask and a 4.8% aqueous sodium hydroxide solution. 0.17 g was added, and the mixture was further stirred at 95 to 119 ° C. while distilling ethanol. After 2 hours, the pressure in the tank was gradually lowered to 8 kPa, and the mixture was further stirred at 116 to 119 ° C. for 3 hours while distilling ethanol. After 3 hours, cooling and releasing the reduced pressure, followed by filtration, poly (geranyloxy) siloxane (in formula (1), X = Y = -OR ² and R ² is a residue obtained by removing the hydroxyl group from geraniol, 65.39 g of a pale yellow oil containing n is an average of 4 compounds).

Synthesis example 2
In the same manner as in Synthesis Example 1 except that 62.93 g (0.41 mol) of nerol (boiling point 227 ° C., log P value 2.77) was used instead of geraniol, poly (neryloxy) siloxane (in formula (1), X = Y = —OR ² , R ² is a residue obtained by removing a hydroxyl group from nerol, and n is an average 4 compound).

Synthesis example 3
A poly (phenylethyloxy) siloxane (formula (1)) was prepared in the same manner as in Synthesis Example 1 except that 49.85 g (0.41 mol) of phenylethyl alcohol (boiling point 220 ° C., log P value 1.18) was used instead of geraniol. In which X = Y = —OR ² , R ² is a residue obtained by removing a hydroxyl group from phenylethyl alcohol, and n is a compound having an average of 4).

Synthesis example 4
In a 200 mL four-necked flask, put 35.45 g (0.17 mol) of tetraethoxysilane, 100.26 g (0.65 mol) of geraniol, and 1.34 mL of 2.8% sodium methoxide methanol solution. The mixture was stirred at 118 to 120 ° C. for about 2 hours. After 2 hours, the pressure in the tank was gradually lowered to 8 kPa, and the mixture was further stirred at 112 to 119 ° C. for 3 hours while distilling ethanol. After 3 hours, cooling and releasing the reduced pressure, followed by filtration, tetrakis (geranyloxy) silane (in formula (1), X = -OR ² , R ² is a residue obtained by removing a hydroxyl group from geraniol, n is A light brown oil containing 0) was obtained.

Synthesis example 5
Tetrakis (citroneloxy) silane (in formula (1), X is the same as in Synthesis Example 4 except that 101.57 g (0.65 mol) of citronellol (boiling point 225 ° C., log P value 3.26) is used instead of geraniol. = -OR ² , R ² is a residue obtained by removing the hydroxyl group from citronellol, and n is a compound having n of 0).

Synthesis Example 6
Tetrakis (phenylethyloxy) silane (in formula (1), X = —OR ² , R ² ) in the same manner as in Synthesis Example 4 except that 79.41 g (0.65 mol) of phenylethyl alcohol is used instead of geraniol. Is a residue obtained by removing a hydroxyl group from phenylethyl alcohol, and n is a compound of 0).

Synthesis example 7
Tetrakis ( cis-3- hexenonyloxy) was synthesized in the same manner as in Synthesis Example 4 except that 64.74 g (0.65 mol) of cis-3-hexenol (boiling point 156 ° C., log P value 1.40) was used instead of geraniol. A light brown oily substance containing silane (in formula (1), X = —OR ² , R ² is a residue obtained by removing a hydroxyl group from cis-3-hexenol , and n is 0) was obtained.

Examples 1-7 and Comparative Examples 1-4
(A) The compound obtained in Synthesis Examples 1 to 7 as the component, the compound shown below as the component (b), and the alcohol shown in Table 1, and a non-contact type antifungal agent composition of the formulation shown in Table 1 Was prepared. About the obtained non-contact-type antifungal agent composition, antifungal performance was evaluated by the following method. The results are shown in Table 1.

<(B) component>
B-1: Diethylene glycol monodecyl ether b-2: Dipropylene glycol monooctyl ether <Antifungal performance evaluation method>
(1) Preparation of Test Bacteria Aspergillus niger and Cladosporium spores and mycelia grown on potato dextrose agar medium (manufactured by Wako Pure Chemical Industries, Ltd.) were dispersed in a sterilized 0.05% Tween80 (Rheodor TW-0120) aqueous solution and 1 × A mold suspension of 10 ⁶ to 1 × 10 ⁷ cells / mL was prepared.

(2) Preparation of mold test piece Cotton melias cloth cut to 3 cm x 3 cm and black dyed cotton broad cloth were sterilized (autoclave: 2 atm (202650 Pa), 125 ° C / 15 min), and 90 mm plastic as shown in Fig. 1 Two pieces each were allowed to stand on Petri dish 1 (Nissui Pharmaceutical, Nissui A Petri dish, sterilized shallow mold). 200 μL of a 2.4% potato dextrose broth aqueous solution (manufactured by Wako Pure Chemical Industries, Ltd.) sterilized on each test cloth was applied, and 100 μL of the above mold suspension was applied as a mold test piece 2, 2 ′.

(3) Mold prevention test A cloth 4 (cotton melias cloth, 1.5 cm × 1.5 cm) impregnated with 20 μL of the non-contact type fungicide composition shown in Table 1 was applied to the center of the petri lid 3, 25 The cells were cultured at 100 ° C. and 100% RH for 7 days. Mold test pieces 2 and 2 ′ were newly prepared by the above method, and the petri dish lid 3 after 7 days of culture was replaced, and cultured again at 25 ° C. and 100% RH for 7 days. After repeating this 10 times, the growth state of the mold was visually observed and evaluated based on the following five criteria. Among them, those with a rating of-and + suppress the growth of mold, and the antifungal effect can be recognized remarkably. In addition, when the growth state of mold | fungi was observed similarly without sticking the cloth which impregnated the non-contact-type antifungal agent composition on the petri dish lid | cover, it confirmed that the antifungal effect was not recognized. The results are shown in Table 1.
-: No mold growth +: Only mildew mycelium grows slightly ++: Only mildew mycelium grows +++: In addition to mold mycelium, mildew spores grow slightly +++++: Both mold spores and mycelia are sufficient Growing in

表１から、比較例１〜４の組成物は、Aspergillus nigerもしくはCladosporiumに対する防カビ性能が不十分であるのに対し、実施例１〜７の非接触型防カビ剤組成物は、Aspergillus niger及びCladosporiumのいずれに対しても防カビ性能が高いことが分かる。

From Table 1, the compositions of Comparative Examples 1 to 4 have insufficient antifungal performance against Aspergillus niger or Cladosporium, whereas the non-contact antifungal compositions of Examples 1 to 7 are Aspergillus niger and It can be seen that the mold prevention performance is high against any of Cladosporium.

Example 8
A non-contact type anti-fungal agent was impregnated in a non-woven fabric (Toyobo Co., Ltd., Toyobo Spunbond, Borans 4301N) with 150% by mass of the non-contact anti-fungal composition of the formulation shown in Example 1 of Table 1. A composition-impregnated nonwoven fabric was prepared. In the plastic storage box (64 cm × 40 cm × 23 cm, made by Yoshikawa, Neo Tenor Middle M23) having an internal volume of about 60 L, 1.7 g of the non-contact type fungicide composition-impregnated nonwoven fabric and the same mold test as in Example 1 The pieces 2 and 2 'were left standing with the petri dish 1 removed. After culturing at 25 ° C. and 100% RH for 7 days, the mold test pieces 2 and 2 ′ were newly prepared in the same manner as in Example 1, and again cultured at 25 ° C. and 100% RH for 7 days. After repeating this 10 times, the fungicidal effect was determined in the same manner as in Example 1. As a result, the determination was “−” for both Aspergillus niger and Cladosporium, and the mold prevention performance was high.

In an Example, it is the schematic of the petri dish used for evaluation of mold prevention performance.

Explanation of symbols

DESCRIPTION OF SYMBOLS 1 Petri dish 2,2 'Mold test piece 3 Petri dish cover 4 Cloth impregnated with non-contact type fungicide composition

Claims (5)

A non-contact type fungicide composition containing the following component (a).
(A) Component: at least one selected from compounds represented by the general formula (1)

[Wherein, X is —OH, —R ¹ or —OR ² , R ¹ is a hydrocarbon group having 1 to 22 carbon atoms, —OR ² is 6 to 15 carbon atoms, and has a boiling point of 150 to 280. C is a residue of an alcohol having a log P value of 1 to 4, Y is X or —OSi (X) ₃ , and n is a number from 0 to 15 indicating an average value. A plurality of X and Y may be the same or different, but have at least one —OR ^{2 in} one molecule. ] In the general formula (1), straight-chain or branched-chain aliphatic alcohols -OR ² is 6 to 11 carbon atoms, terpene alcohols, alicyclic alcohols having 7 to 15 carbon atoms, an arylalkyl alcohol having 7 to 15 carbon atoms Or the non-contact type | mold antifungal agent composition of Claim 1 which is the residue of the alcohol chosen from alkylaryl alcohol. Furthermore, the non-contact type | mold antifungal agent composition of Claim 1 or 2 containing the following (b) component.
(B) Component: At least one selected from the compound represented by the general formula (2) R ³ —O (AO) _m H (2)
[In the formula, R ³ is an alkyl group having 7 to 11 carbon atoms, A is an alkylene group having 2 to 3 carbon atoms, m is a number of 1 to 3 indicating an average added mole number, and m A's may be the same. It may be different. ]   The non-contact type antifungal agent according to claim 3, wherein the blending ratio of the component (a) and the component (b) in the composition is (a) / (b) (mass ratio) = 100/1 to 1/100. Composition.   The anti-fungal agent composition package which accommodates the non-contact-type anti-fungal agent composition in any one of Claims 1-4 in a container.

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