JP2017105802A5 - - Google Patents
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- Publication number
- JP2017105802A5 JP2017105802A5 JP2017012663A JP2017012663A JP2017105802A5 JP 2017105802 A5 JP2017105802 A5 JP 2017105802A5 JP 2017012663 A JP2017012663 A JP 2017012663A JP 2017012663 A JP2017012663 A JP 2017012663A JP 2017105802 A5 JP2017105802 A5 JP 2017105802A5
- Authority
- JP
- Japan
- Prior art keywords
- vesicle
- pharmaceutical composition
- blood
- polymer
- glucose
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2013242347 | 2013-11-22 | ||
| JP2013242347 | 2013-11-22 | ||
| JP2014096935 | 2014-05-08 | ||
| JP2014096935 | 2014-05-08 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015548997A Division JP6086566B2 (ja) | 2013-11-22 | 2014-11-21 | 薬剤送達用のキャリア、コンジュゲートおよびこれらを含んでなる組成物並びにこれらの投与方法 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019116818A Division JP2019194220A (ja) | 2013-11-22 | 2019-06-25 | 薬剤送達用のキャリア、コンジュゲートおよびこれらを含んでなる組成物並びにこれらの投与方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017105802A JP2017105802A (ja) | 2017-06-15 |
| JP2017105802A5 true JP2017105802A5 (cg-RX-API-DMAC7.html) | 2018-02-15 |
| JP6782415B2 JP6782415B2 (ja) | 2020-11-11 |
Family
ID=53179224
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015548997A Expired - Fee Related JP6086566B2 (ja) | 2013-11-22 | 2014-11-21 | 薬剤送達用のキャリア、コンジュゲートおよびこれらを含んでなる組成物並びにこれらの投与方法 |
| JP2017012663A Expired - Fee Related JP6782415B2 (ja) | 2013-11-22 | 2017-01-27 | 薬剤送達用のキャリア、コンジュゲートおよびこれらを含んでなる組成物並びにこれらの投与方法 |
| JP2019116818A Pending JP2019194220A (ja) | 2013-11-22 | 2019-06-25 | 薬剤送達用のキャリア、コンジュゲートおよびこれらを含んでなる組成物並びにこれらの投与方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015548997A Expired - Fee Related JP6086566B2 (ja) | 2013-11-22 | 2014-11-21 | 薬剤送達用のキャリア、コンジュゲートおよびこれらを含んでなる組成物並びにこれらの投与方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019116818A Pending JP2019194220A (ja) | 2013-11-22 | 2019-06-25 | 薬剤送達用のキャリア、コンジュゲートおよびこれらを含んでなる組成物並びにこれらの投与方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US9937263B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP3072506B1 (cg-RX-API-DMAC7.html) |
| JP (3) | JP6086566B2 (cg-RX-API-DMAC7.html) |
| CN (2) | CN105899192B (cg-RX-API-DMAC7.html) |
| CA (1) | CA2931056C (cg-RX-API-DMAC7.html) |
| WO (1) | WO2015075942A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015075942A1 (ja) * | 2013-11-22 | 2015-05-28 | 国立大学法人 東京大学 | 薬剤送達用のキャリア、コンジュゲートおよびこれらを含んでなる組成物並びにこれらの投与方法 |
| US20180185281A1 (en) * | 2015-07-02 | 2018-07-05 | The University Of Tokyo | Drug delivery carrier, and composition containing same |
| CN109476841B (zh) * | 2016-07-30 | 2021-08-24 | 日本化药株式会社 | 新型高分子衍生物和使用其的新型高分子衍生物成像探针 |
| US11433089B2 (en) | 2016-09-23 | 2022-09-06 | National University Corporation Tokyo Medical And Dental University | Blood-brain barrier permeable heteroduplex nucleic acid |
| CN110168090B (zh) * | 2016-12-27 | 2023-07-18 | 国立大学法人东京大学 | mRNA的功能化方法 |
| WO2018207864A1 (ja) * | 2017-05-11 | 2018-11-15 | 公益財団法人川崎市産業振興財団 | 脳への薬剤送達用のキャリアおよびこれを含んでなる組成物 |
| JPWO2019009434A1 (ja) * | 2017-07-06 | 2020-07-02 | 学校法人京都薬科大学 | 薬物送達用高分子ミセル |
| JP2019069933A (ja) | 2017-10-05 | 2019-05-09 | 公益財団法人川崎市産業振興財団 | 体内における薬物動態を制御する組成物 |
| US11851654B2 (en) | 2018-03-19 | 2023-12-26 | National University Corporation Tokyo Medical And Dental University | Nucleic acid with reduced toxicity |
| WO2019240223A1 (ja) * | 2018-06-13 | 2019-12-19 | 公益財団法人川崎市産業振興財団 | 数平均分子量が３ｋＤａ～１０ｋＤａであるＰＥＧブロックとカチオン性ポリマーとのブロックコポリマーと、アンチセンスオリゴヌクレオチドとを含む、ポリイオンコンプレックスミセル |
| WO2020116635A1 (ja) * | 2018-12-07 | 2020-06-11 | 国立大学法人 東京大学 | 輸送担体を用いた環状化合物の送達 |
| JP7600101B2 (ja) | 2019-04-26 | 2024-12-16 | 公益財団法人川崎市産業振興財団 | 抗体の抗原結合性断片を脳へ送達するための方法および組成物 |
| WO2020230793A1 (ja) * | 2019-05-13 | 2020-11-19 | 国立大学法人東京大学 | 血中からの中空ナノ粒子の脳への移行制御技術 |
| WO2021193393A1 (en) * | 2020-03-26 | 2021-09-30 | Kawasaki Institute Of Industrial Promotion | A method of administering a nanoparticle |
| WO2021207382A1 (en) * | 2020-04-08 | 2021-10-14 | The Johns Hopkins University | D-glucose and its analogs as tracers to assess the glucose transporter function |
| EP4342497A1 (en) | 2021-05-10 | 2024-03-27 | Kawasaki Institute of Industrial Promotion | Antibody having reduced binding affinity for antigen |
| EP4387607A4 (en) * | 2021-08-16 | 2026-06-24 | Tiba Biotech Llc | NANOPARTICLE COMPOSITIONS CONTAINING SUGAR-FUNCTIONALIZED NUCLEIC ACID VECTORS |
| EP4404976A1 (en) * | 2021-09-25 | 2024-07-31 | Nutaria Ltd. | Targeted encapsulation strategies for treatment modalities |
| WO2023210233A1 (ja) * | 2022-04-27 | 2023-11-02 | 国立大学法人東海国立大学機構 | 糖連結ポリヌクレオチド |
| CN116510028A (zh) * | 2023-04-18 | 2023-08-01 | 大连理工大学 | 一种跨血脑屏障的基因递送载体及其制备方法和应用 |
| WO2025221757A1 (en) * | 2024-04-15 | 2025-10-23 | Board Of Regents, The University Of Texas System | Carbohydrate-polymer conjugates for tunable protein binding on the blood brain barrier and methods of use |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005076011A2 (en) * | 2004-01-30 | 2005-08-18 | Xenoport, Inc. | Use of glut1 transporter expressed in blood brain barrier cells for screening for pharmacologically active substances |
| CA2632828C (en) | 2005-12-12 | 2012-07-10 | F. Hoffmann-La Roche Ag | Antibodies against amyloid beta with glycosylation in the variable region |
| EP2222279A2 (en) * | 2007-12-10 | 2010-09-01 | Epitarget AS | Acoustically sensitive drug delivery particles comprising non-lamellar forming lipids |
| UA104742C2 (uk) * | 2008-12-19 | 2014-03-11 | Эли Лилли Энд Компани | Похідні арилциклопропілацетаміду, застосовні як активатори глюкокінази |
| EP2382994A1 (en) * | 2010-04-26 | 2011-11-02 | Maurizio Victor Cattaneo | Ligand targeted nanocapsules for the delivery of RNAi and other agents |
| WO2011145745A1 (ja) * | 2010-05-21 | 2011-11-24 | 独立行政法人科学技術振興機構 | 物質内包ベシクル及びその製造方法 |
| WO2015075942A1 (ja) * | 2013-11-22 | 2015-05-28 | 国立大学法人 東京大学 | 薬剤送達用のキャリア、コンジュゲートおよびこれらを含んでなる組成物並びにこれらの投与方法 |
-
2014
- 2014-11-21 WO PCT/JP2014/005856 patent/WO2015075942A1/ja not_active Ceased
- 2014-11-21 CN CN201480063806.3A patent/CN105899192B/zh not_active Expired - Fee Related
- 2014-11-21 EP EP14863728.3A patent/EP3072506B1/en not_active Not-in-force
- 2014-11-21 CN CN201910638349.0A patent/CN110302394A/zh active Pending
- 2014-11-21 JP JP2015548997A patent/JP6086566B2/ja not_active Expired - Fee Related
- 2014-11-21 CA CA2931056A patent/CA2931056C/en active Active
- 2014-11-21 US US15/038,374 patent/US9937263B2/en not_active Expired - Fee Related
-
2017
- 2017-01-27 JP JP2017012663A patent/JP6782415B2/ja not_active Expired - Fee Related
-
2018
- 2018-02-22 US US15/902,255 patent/US10912838B2/en not_active Expired - Fee Related
-
2019
- 2019-06-25 JP JP2019116818A patent/JP2019194220A/ja active Pending
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