JP2017048128A - Hair washing agent composition - Google Patents
Hair washing agent composition Download PDFInfo
- Publication number
- JP2017048128A JP2017048128A JP2015170798A JP2015170798A JP2017048128A JP 2017048128 A JP2017048128 A JP 2017048128A JP 2015170798 A JP2015170798 A JP 2015170798A JP 2015170798 A JP2015170798 A JP 2015170798A JP 2017048128 A JP2017048128 A JP 2017048128A
- Authority
- JP
- Japan
- Prior art keywords
- hair
- weight
- extract
- component
- cleansing composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 55
- 238000005406 washing Methods 0.000 title abstract description 12
- -1 alkyl ether sulfate Chemical class 0.000 claims abstract description 35
- 239000003795 chemical substances by application Substances 0.000 claims abstract description 19
- 229920000926 Galactomannan Polymers 0.000 claims abstract description 17
- OMDQUFIYNPYJFM-XKDAHURESA-N (2r,3r,4s,5r,6s)-2-(hydroxymethyl)-6-[[(2r,3s,4r,5s,6r)-4,5,6-trihydroxy-3-[(2s,3s,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]methoxy]oxane-3,4,5-triol Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@@H]1OC[C@@H]1[C@@H](O[C@H]2[C@H]([C@@H](O)[C@H](O)[C@@H](CO)O2)O)[C@H](O)[C@H](O)[C@H](O)O1 OMDQUFIYNPYJFM-XKDAHURESA-N 0.000 claims abstract description 16
- 239000002280 amphoteric surfactant Substances 0.000 claims abstract description 11
- 235000014113 dietary fatty acids Nutrition 0.000 claims abstract description 8
- 239000000194 fatty acid Substances 0.000 claims abstract description 8
- 229930195729 fatty acid Natural products 0.000 claims abstract description 8
- 230000007935 neutral effect Effects 0.000 claims abstract description 8
- 125000001183 hydrocarbyl group Chemical group 0.000 claims abstract description 7
- 229910017053 inorganic salt Inorganic materials 0.000 claims abstract description 7
- 150000004665 fatty acids Chemical class 0.000 claims abstract description 6
- 239000002888 zwitterionic surfactant Substances 0.000 claims abstract description 6
- 125000002947 alkylene group Chemical group 0.000 claims abstract description 5
- 239000003945 anionic surfactant Substances 0.000 claims abstract description 5
- 239000002736 nonionic surfactant Substances 0.000 claims abstract description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 4
- 239000008213 purified water Substances 0.000 claims abstract description 3
- 229920001296 polysiloxane Polymers 0.000 claims description 17
- 230000000694 effects Effects 0.000 claims description 12
- 125000004432 carbon atom Chemical group C* 0.000 claims description 9
- 230000003700 hair damage Effects 0.000 claims description 5
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims description 4
- 244000007835 Cyamopsis tetragonoloba Species 0.000 claims description 2
- 239000006260 foam Substances 0.000 abstract description 35
- 230000003750 conditioning effect Effects 0.000 abstract description 16
- 238000001035 drying Methods 0.000 abstract description 8
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 239000000284 extract Substances 0.000 description 34
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 description 11
- 230000000052 comparative effect Effects 0.000 description 9
- 238000011156 evaluation Methods 0.000 description 9
- 238000002156 mixing Methods 0.000 description 9
- 239000003921 oil Substances 0.000 description 9
- 235000019198 oils Nutrition 0.000 description 9
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 6
- 239000002253 acid Substances 0.000 description 6
- 229920001577 copolymer Polymers 0.000 description 6
- 230000008719 thickening Effects 0.000 description 6
- 229920003171 Poly (ethylene oxide) Polymers 0.000 description 5
- 239000013543 active substance Substances 0.000 description 5
- 238000005354 coacervation Methods 0.000 description 5
- 239000004205 dimethyl polysiloxane Substances 0.000 description 5
- 235000013870 dimethyl polysiloxane Nutrition 0.000 description 5
- 238000000034 method Methods 0.000 description 5
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 5
- PVNIIMVLHYAWGP-UHFFFAOYSA-N nicotinic acid Natural products OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 description 5
- WQZGKKKJIJFFOK-QTVWNMPRSA-N D-mannopyranose Chemical compound OC[C@H]1OC(O)[C@@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-QTVWNMPRSA-N 0.000 description 4
- XLOMVQKBTHCTTD-UHFFFAOYSA-N Zinc monoxide Chemical compound [Zn]=O XLOMVQKBTHCTTD-UHFFFAOYSA-N 0.000 description 4
- KVYGGMBOZFWZBQ-UHFFFAOYSA-N benzyl nicotinate Chemical compound C=1C=CN=CC=1C(=O)OCC1=CC=CC=C1 KVYGGMBOZFWZBQ-UHFFFAOYSA-N 0.000 description 4
- RYYVLZVUVIJVGH-UHFFFAOYSA-N caffeine Chemical compound CN1C(=O)N(C)C(=O)C2=C1N=CN2C RYYVLZVUVIJVGH-UHFFFAOYSA-N 0.000 description 4
- 229920006317 cationic polymer Polymers 0.000 description 4
- 238000009472 formulation Methods 0.000 description 4
- 239000007788 liquid Substances 0.000 description 4
- 239000002453 shampoo Substances 0.000 description 4
- 229920002907 Guar gum Polymers 0.000 description 3
- 240000007594 Oryza sativa Species 0.000 description 3
- 235000007164 Oryza sativa Nutrition 0.000 description 3
- AUNGANRZJHBGPY-SCRDCRAPSA-N Riboflavin Chemical compound OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-SCRDCRAPSA-N 0.000 description 3
- 125000004442 acylamino group Chemical group 0.000 description 3
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 description 3
- 238000004140 cleaning Methods 0.000 description 3
- 229940008099 dimethicone Drugs 0.000 description 3
- 239000003814 drug Substances 0.000 description 3
- 239000012847 fine chemical Substances 0.000 description 3
- 238000005187 foaming Methods 0.000 description 3
- 239000000665 guar gum Substances 0.000 description 3
- 235000010417 guar gum Nutrition 0.000 description 3
- 229960002154 guar gum Drugs 0.000 description 3
- 229960003512 nicotinic acid Drugs 0.000 description 3
- 235000001968 nicotinic acid Nutrition 0.000 description 3
- 239000011664 nicotinic acid Substances 0.000 description 3
- 239000000047 product Substances 0.000 description 3
- 235000009566 rice Nutrition 0.000 description 3
- 150000003839 salts Chemical class 0.000 description 3
- 230000001953 sensory effect Effects 0.000 description 3
- 239000011780 sodium chloride Substances 0.000 description 3
- 239000004094 surface-active agent Substances 0.000 description 3
- 229940088594 vitamin Drugs 0.000 description 3
- 229930003231 vitamin Natural products 0.000 description 3
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 description 2
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 description 2
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 description 2
- XDOFQFKRPWOURC-UHFFFAOYSA-N 16-methylheptadecanoic acid Chemical compound CC(C)CCCCCCCCCCCCCCC(O)=O XDOFQFKRPWOURC-UHFFFAOYSA-N 0.000 description 2
- PCGKIWPTIJPQHI-UHFFFAOYSA-N 16-methyloctadecanoic acid Chemical compound CCC(C)CCCCCCCCCCCCCCC(O)=O PCGKIWPTIJPQHI-UHFFFAOYSA-N 0.000 description 2
- WSRCOZWDQPJAQT-UHFFFAOYSA-N 18-methylicosanoic acid Chemical compound CCC(C)CCCCCCCCCCCCCCCCC(O)=O WSRCOZWDQPJAQT-UHFFFAOYSA-N 0.000 description 2
- AKWFJQNBHYVIPY-UHFFFAOYSA-N 2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol Chemical compound OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO AKWFJQNBHYVIPY-UHFFFAOYSA-N 0.000 description 2
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 2
- 240000003538 Chamaemelum nobile Species 0.000 description 2
- 235000007866 Chamaemelum nobile Nutrition 0.000 description 2
- AUNGANRZJHBGPY-UHFFFAOYSA-N D-Lyxoflavin Natural products OCC(O)C(O)C(O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-UHFFFAOYSA-N 0.000 description 2
- ZAKOWWREFLAJOT-CEFNRUSXSA-N D-alpha-tocopherylacetate Chemical compound CC(=O)OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C ZAKOWWREFLAJOT-CEFNRUSXSA-N 0.000 description 2
- RGHNJXZEOKUKBD-SQOUGZDYSA-N D-gluconic acid Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O RGHNJXZEOKUKBD-SQOUGZDYSA-N 0.000 description 2
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 description 2
- LPHGQDQBBGAPDZ-UHFFFAOYSA-N Isocaffeine Natural products CN1C(=O)N(C)C(=O)C2=C1N(C)C=N2 LPHGQDQBBGAPDZ-UHFFFAOYSA-N 0.000 description 2
- TWRXJAOTZQYOKJ-UHFFFAOYSA-L Magnesium chloride Chemical compound [Mg+2].[Cl-].[Cl-] TWRXJAOTZQYOKJ-UHFFFAOYSA-L 0.000 description 2
- WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 description 2
- 241000220317 Rosa Species 0.000 description 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 2
- MSCCTZZBYHQMQJ-AZAGJHQNSA-N Tocopheryl nicotinate Chemical compound C([C@@](OC1=C(C)C=2C)(C)CCC[C@H](C)CCC[C@H](C)CCCC(C)C)CC1=C(C)C=2OC(=O)C1=CC=CN=C1 MSCCTZZBYHQMQJ-AZAGJHQNSA-N 0.000 description 2
- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 description 2
- POJWUDADGALRAB-UHFFFAOYSA-N allantoin Chemical compound NC(=O)NC1NC(=O)NC1=O POJWUDADGALRAB-UHFFFAOYSA-N 0.000 description 2
- 229940024606 amino acid Drugs 0.000 description 2
- 229940053200 antiepileptics fatty acid derivative Drugs 0.000 description 2
- 239000010478 argan oil Substances 0.000 description 2
- 229950004580 benzyl nicotinate Drugs 0.000 description 2
- FUWUEFKEXZQKKA-UHFFFAOYSA-N beta-thujaplicin Chemical compound CC(C)C=1C=CC=C(O)C(=O)C=1 FUWUEFKEXZQKKA-UHFFFAOYSA-N 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 229960001948 caffeine Drugs 0.000 description 2
- VJEONQKOZGKCAK-UHFFFAOYSA-N caffeine Natural products CN1C(=O)N(C)C(=O)C2=C1C=CN2C VJEONQKOZGKCAK-UHFFFAOYSA-N 0.000 description 2
- YKPUWZUDDOIDPM-SOFGYWHQSA-N capsaicin Chemical compound COC1=CC(CNC(=O)CCCC\C=C\C(C)C)=CC=C1O YKPUWZUDDOIDPM-SOFGYWHQSA-N 0.000 description 2
- 229940007061 capsicum extract Drugs 0.000 description 2
- 239000001943 capsicum frutescens fruit extract Substances 0.000 description 2
- 239000003240 coconut oil Substances 0.000 description 2
- 235000019864 coconut oil Nutrition 0.000 description 2
- 238000013329 compounding Methods 0.000 description 2
- 150000001875 compounds Chemical class 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 239000000839 emulsion Substances 0.000 description 2
- 239000012530 fluid Substances 0.000 description 2
- 230000005484 gravity Effects 0.000 description 2
- BJRNKVDFDLYUGJ-RMPHRYRLSA-N hydroquinone O-beta-D-glucopyranoside Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=CC=C(O)C=C1 BJRNKVDFDLYUGJ-RMPHRYRLSA-N 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- 239000013500 performance material Substances 0.000 description 2
- 229920000642 polymer Polymers 0.000 description 2
- 229920001451 polypropylene glycol Polymers 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 description 2
- ZUFQODAHGAHPFQ-UHFFFAOYSA-N pyridoxine hydrochloride Chemical compound Cl.CC1=NC=C(CO)C(CO)=C1O ZUFQODAHGAHPFQ-UHFFFAOYSA-N 0.000 description 2
- 229960002477 riboflavin Drugs 0.000 description 2
- ZFDPAZDODACYOG-UHFFFAOYSA-M sodium;[(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)amino]methanesulfonate Chemical compound [Na+].CN1C(C)=C(NCS([O-])(=O)=O)C(=O)N1C1=CC=CC=C1 ZFDPAZDODACYOG-UHFFFAOYSA-M 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- PRAKJMSDJKAYCZ-UHFFFAOYSA-N squalane Chemical compound CC(C)CCCC(C)CCCC(C)CCCCC(C)CCCC(C)CCCC(C)C PRAKJMSDJKAYCZ-UHFFFAOYSA-N 0.000 description 2
- 229920001864 tannin Polymers 0.000 description 2
- 235000018553 tannin Nutrition 0.000 description 2
- 239000001648 tannin Substances 0.000 description 2
- 229940042585 tocopherol acetate Drugs 0.000 description 2
- 235000015112 vegetable and seed oil Nutrition 0.000 description 2
- 239000008158 vegetable oil Substances 0.000 description 2
- 235000013343 vitamin Nutrition 0.000 description 2
- 239000011782 vitamin Substances 0.000 description 2
- 239000011787 zinc oxide Substances 0.000 description 2
- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 description 2
- HDTRYLNUVZCQOY-UHFFFAOYSA-N α-D-glucopyranosyl-α-D-glucopyranoside Natural products OC1C(O)C(O)C(CO)OC1OC1C(O)C(O)C(O)C(CO)O1 HDTRYLNUVZCQOY-UHFFFAOYSA-N 0.000 description 1
- ZXFNOEJFYLQUSB-UHFFFAOYSA-N (2-methyl-4-phenylbutan-2-yl) acetate Chemical compound CC(=O)OC(C)(C)CCC1=CC=CC=C1 ZXFNOEJFYLQUSB-UHFFFAOYSA-N 0.000 description 1
- MTCFGRXMJLQNBG-REOHCLBHSA-N (2S)-2-Amino-3-hydroxypropansäure Chemical compound OC[C@H](N)C(O)=O MTCFGRXMJLQNBG-REOHCLBHSA-N 0.000 description 1
- PBTPTBMYJPCXRQ-MGMRMFRLSA-N (2r)-2-[(1s)-1,2-dihydroxyethyl]-3,4-dihydroxy-2h-furan-5-one;hexadecanoic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O.CCCCCCCCCCCCCCCC(O)=O PBTPTBMYJPCXRQ-MGMRMFRLSA-N 0.000 description 1
- DBSABEYSGXPBTA-RXSVEWSESA-N (2r)-2-[(1s)-1,2-dihydroxyethyl]-3,4-dihydroxy-2h-furan-5-one;phosphoric acid Chemical compound OP(O)(O)=O.OC[C@H](O)[C@H]1OC(=O)C(O)=C1O DBSABEYSGXPBTA-RXSVEWSESA-N 0.000 description 1
- MRAMPOPITCOOIN-VIFPVBQESA-N (2r)-n-(3-ethoxypropyl)-2,4-dihydroxy-3,3-dimethylbutanamide Chemical compound CCOCCCNC(=O)[C@H](O)C(C)(C)CO MRAMPOPITCOOIN-VIFPVBQESA-N 0.000 description 1
- FTNJQNQLEGKTGD-UHFFFAOYSA-N 1,3-benzodioxole Chemical compound C1=CC=C2OCOC2=C1 FTNJQNQLEGKTGD-UHFFFAOYSA-N 0.000 description 1
- TUSDEZXZIZRFGC-UHFFFAOYSA-N 1-O-galloyl-3,6-(R)-HHDP-beta-D-glucose Natural products OC1C(O2)COC(=O)C3=CC(O)=C(O)C(O)=C3C3=C(O)C(O)=C(O)C=C3C(=O)OC1C(O)C2OC(=O)C1=CC(O)=C(O)C(O)=C1 TUSDEZXZIZRFGC-UHFFFAOYSA-N 0.000 description 1
- RYCNUMLMNKHWPZ-SNVBAGLBSA-N 1-acetyl-sn-glycero-3-phosphocholine Chemical compound CC(=O)OC[C@@H](O)COP([O-])(=O)OCC[N+](C)(C)C RYCNUMLMNKHWPZ-SNVBAGLBSA-N 0.000 description 1
- WRGQSWVCFNIUNZ-GDCKJWNLSA-N 1-oleoyl-sn-glycerol 3-phosphate Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@@H](O)COP(O)(O)=O WRGQSWVCFNIUNZ-GDCKJWNLSA-N 0.000 description 1
- ZONJATNKKGGVSU-UHFFFAOYSA-N 14-methylpentadecanoic acid Chemical compound CC(C)CCCCCCCCCCCCC(O)=O ZONJATNKKGGVSU-UHFFFAOYSA-N 0.000 description 1
- MPDGHEJMBKOTSU-YKLVYJNSSA-N 18beta-glycyrrhetic acid Chemical class C([C@H]1C2=CC(=O)[C@H]34)[C@@](C)(C(O)=O)CC[C@]1(C)CC[C@@]2(C)[C@]4(C)CC[C@@H]1[C@]3(C)CC[C@H](O)C1(C)C MPDGHEJMBKOTSU-YKLVYJNSSA-N 0.000 description 1
- SGTNSNPWRIOYBX-UHFFFAOYSA-N 2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile Chemical compound C1=C(OC)C(OC)=CC=C1CCN(C)CCCC(C#N)(C(C)C)C1=CC=C(OC)C(OC)=C1 SGTNSNPWRIOYBX-UHFFFAOYSA-N 0.000 description 1
- XMTCKNXTTXDPJX-UHFFFAOYSA-N 3-oxoalanine Chemical compound O=CC(N)C(O)=O XMTCKNXTTXDPJX-UHFFFAOYSA-N 0.000 description 1
- MOMKYJPSVWEWPM-UHFFFAOYSA-N 4-(chloromethyl)-2-(4-methylphenyl)-1,3-thiazole Chemical compound C1=CC(C)=CC=C1C1=NC(CCl)=CS1 MOMKYJPSVWEWPM-UHFFFAOYSA-N 0.000 description 1
- IELOKBJPULMYRW-IKTKBOKFSA-N 4-oxo-4-[[(2S)-2,5,7,8-tetramethyl-2-[(4S,8S)-4,8,12-trimethyltridecyl]-3,4-dihydrochromen-6-yl]oxy]butanoic acid Chemical compound CC(C)CCC[C@H](C)CCC[C@H](C)CCC[C@@](C)(CC1)Oc(c(C)c2C)c1c(C)c2OC(CCC(O)=O)=O IELOKBJPULMYRW-IKTKBOKFSA-N 0.000 description 1
- 235000001674 Agaricus brunnescens Nutrition 0.000 description 1
- POJWUDADGALRAB-PVQJCKRUSA-N Allantoin Natural products NC(=O)N[C@@H]1NC(=O)NC1=O POJWUDADGALRAB-PVQJCKRUSA-N 0.000 description 1
- 235000019489 Almond oil Nutrition 0.000 description 1
- 239000004475 Arginine Substances 0.000 description 1
- 235000018185 Betula X alpestris Nutrition 0.000 description 1
- 235000018212 Betula X uliginosa Nutrition 0.000 description 1
- FXUKWLSZZHVEJD-UHFFFAOYSA-N C16:0-14-methyl Natural products CCC(C)CCCCCCCCCCCCC(O)=O FXUKWLSZZHVEJD-UHFFFAOYSA-N 0.000 description 1
- 239000001884 Cassia gum Substances 0.000 description 1
- 235000005940 Centaurea cyanus Nutrition 0.000 description 1
- 240000004385 Centaurea cyanus Species 0.000 description 1
- 241000951471 Citrus junos Species 0.000 description 1
- 241000544061 Cuculus canorus Species 0.000 description 1
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 description 1
- RGHNJXZEOKUKBD-UHFFFAOYSA-N D-gluconic acid Natural products OCC(O)C(O)C(O)C(O)C(O)=O RGHNJXZEOKUKBD-UHFFFAOYSA-N 0.000 description 1
- SNPLKNRPJHDVJA-ZETCQYMHSA-N D-panthenol Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCCO SNPLKNRPJHDVJA-ZETCQYMHSA-N 0.000 description 1
- 235000004866 D-panthenol Nutrition 0.000 description 1
- 239000011703 D-panthenol Substances 0.000 description 1
- 235000011511 Diospyros Nutrition 0.000 description 1
- 244000236655 Diospyros kaki Species 0.000 description 1
- 241000255925 Diptera Species 0.000 description 1
- ZGTMUACCHSMWAC-UHFFFAOYSA-L EDTA disodium salt (anhydrous) Chemical compound [Na+].[Na+].OC(=O)CN(CC([O-])=O)CCN(CC(O)=O)CC([O-])=O ZGTMUACCHSMWAC-UHFFFAOYSA-L 0.000 description 1
- QZKRHPLGUJDVAR-UHFFFAOYSA-K EDTA trisodium salt Chemical compound [Na+].[Na+].[Na+].OC(=O)CN(CC([O-])=O)CCN(CC([O-])=O)CC([O-])=O QZKRHPLGUJDVAR-UHFFFAOYSA-K 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 244000061508 Eriobotrya japonica Species 0.000 description 1
- 235000009008 Eriobotrya japonica Nutrition 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 239000001263 FEMA 3042 Substances 0.000 description 1
- 235000009419 Fagopyrum esculentum Nutrition 0.000 description 1
- 240000008620 Fagopyrum esculentum Species 0.000 description 1
- 235000010099 Fagus sylvatica Nutrition 0.000 description 1
- 240000000731 Fagus sylvatica Species 0.000 description 1
- 229930091371 Fructose Natural products 0.000 description 1
- 239000005715 Fructose Substances 0.000 description 1
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 description 1
- 239000006000 Garlic extract Substances 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 235000010469 Glycine max Nutrition 0.000 description 1
- 244000068988 Glycine max Species 0.000 description 1
- 241000208690 Hamamelis Species 0.000 description 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 1
- 241000546188 Hypericum Species 0.000 description 1
- 235000017309 Hypericum perforatum Nutrition 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- ODKSFYDXXFIFQN-BYPYZUCNSA-P L-argininium(2+) Chemical compound NC(=[NH2+])NCCC[C@H]([NH3+])C(O)=O ODKSFYDXXFIFQN-BYPYZUCNSA-P 0.000 description 1
- 239000002211 L-ascorbic acid Substances 0.000 description 1
- 239000004166 Lanolin Substances 0.000 description 1
- VTAJIXDZFCRWBR-UHFFFAOYSA-N Licoricesaponin B2 Natural products C1C(C2C(C3(CCC4(C)CCC(C)(CC4C3=CC2)C(O)=O)C)(C)CC2)(C)C2C(C)(C)CC1OC1OC(C(O)=O)C(O)C(O)C1OC1OC(C(O)=O)C(O)C(O)C1O VTAJIXDZFCRWBR-UHFFFAOYSA-N 0.000 description 1
- 241000234435 Lilium Species 0.000 description 1
- 229920000161 Locust bean gum Polymers 0.000 description 1
- 244000280244 Luffa acutangula Species 0.000 description 1
- 235000009814 Luffa aegyptiaca Nutrition 0.000 description 1
- 235000007688 Lycopersicon esculentum Nutrition 0.000 description 1
- 235000018330 Macadamia integrifolia Nutrition 0.000 description 1
- 235000003800 Macadamia tetraphylla Nutrition 0.000 description 1
- 240000000912 Macadamia tetraphylla Species 0.000 description 1
- 229920000057 Mannan Polymers 0.000 description 1
- 235000007232 Matricaria chamomilla Nutrition 0.000 description 1
- 239000004909 Moisturizer Substances 0.000 description 1
- 240000007817 Olea europaea Species 0.000 description 1
- 235000011203 Origanum Nutrition 0.000 description 1
- 240000000783 Origanum majorana Species 0.000 description 1
- 241000736199 Paeonia Species 0.000 description 1
- 235000006484 Paeonia officinalis Nutrition 0.000 description 1
- 241000282372 Panthera onca Species 0.000 description 1
- LRBQNJMCXXYXIU-PPKXGCFTSA-N Penta-digallate-beta-D-glucose Natural products OC1=C(O)C(O)=CC(C(=O)OC=2C(=C(O)C=C(C=2)C(=O)OC[C@@H]2[C@H]([C@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)[C@@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)[C@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)O2)OC(=O)C=2C=C(OC(=O)C=3C=C(O)C(O)=C(O)C=3)C(O)=C(O)C=2)O)=C1 LRBQNJMCXXYXIU-PPKXGCFTSA-N 0.000 description 1
- 235000004347 Perilla Nutrition 0.000 description 1
- 244000124853 Perilla frutescens Species 0.000 description 1
- 239000004721 Polyphenylene oxide Substances 0.000 description 1
- MJNIWUJSIGSWKK-BBANNHEPSA-N Riboflavin butyrate Chemical compound CCCC(=O)OC[C@@H](OC(=O)CCC)[C@@H](OC(=O)CCC)[C@@H](OC(=O)CCC)CN1C2=CC(C)=C(C)C=C2N=C2C1=NC(=O)NC2=O MJNIWUJSIGSWKK-BBANNHEPSA-N 0.000 description 1
- MTCFGRXMJLQNBG-UHFFFAOYSA-N Serine Natural products OCC(N)C(O)=O MTCFGRXMJLQNBG-UHFFFAOYSA-N 0.000 description 1
- 240000003768 Solanum lycopersicum Species 0.000 description 1
- 229930006000 Sucrose Natural products 0.000 description 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 description 1
- 235000019486 Sunflower oil Nutrition 0.000 description 1
- HDTRYLNUVZCQOY-WSWWMNSNSA-N Trehalose Natural products O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-WSWWMNSNSA-N 0.000 description 1
- 235000001484 Trigonella foenum graecum Nutrition 0.000 description 1
- 244000250129 Trigonella foenum graecum Species 0.000 description 1
- FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 description 1
- 229930003471 Vitamin B2 Natural products 0.000 description 1
- LXNHXLLTXMVWPM-UHFFFAOYSA-N Vitamin B6 Natural products CC1=NC=C(CO)C(CO)=C1O LXNHXLLTXMVWPM-UHFFFAOYSA-N 0.000 description 1
- 229930003268 Vitamin C Natural products 0.000 description 1
- 229930003316 Vitamin D Natural products 0.000 description 1
- MECHNRXZTMCUDQ-UHFFFAOYSA-N Vitamin D2 Natural products C1CCC2(C)C(C(C)C=CC(C)C(C)C)CCC2C1=CC=C1CC(O)CCC1=C MECHNRXZTMCUDQ-UHFFFAOYSA-N 0.000 description 1
- 229930003427 Vitamin E Natural products 0.000 description 1
- TVXBFESIOXBWNM-UHFFFAOYSA-N Xylitol Natural products OCCC(O)C(O)C(O)CCO TVXBFESIOXBWNM-UHFFFAOYSA-N 0.000 description 1
- 241000350580 Zenia Species 0.000 description 1
- DFPAKSUCGFBDDF-ZQBYOMGUSA-N [14c]-nicotinamide Chemical compound N[14C](=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-ZQBYOMGUSA-N 0.000 description 1
- PAUSGZCRNOTKPK-UHFFFAOYSA-N [5-hydroxy-6-methyl-4-(octanoyloxymethyl)pyridin-3-yl]methyl octanoate Chemical compound CCCCCCCC(=O)OCC1=CN=C(C)C(O)=C1COC(=O)CCCCCCC PAUSGZCRNOTKPK-UHFFFAOYSA-N 0.000 description 1
- 239000006096 absorbing agent Substances 0.000 description 1
- OIPILFWXSMYKGL-UHFFFAOYSA-N acetylcholine Chemical compound CC(=O)OCC[N+](C)(C)C OIPILFWXSMYKGL-UHFFFAOYSA-N 0.000 description 1
- 229960004373 acetylcholine Drugs 0.000 description 1
- 239000012190 activator Substances 0.000 description 1
- 150000005215 alkyl ethers Chemical class 0.000 description 1
- 229960000458 allantoin Drugs 0.000 description 1
- 239000008168 almond oil Substances 0.000 description 1
- 229940069521 aloe extract Drugs 0.000 description 1
- 235000014104 aloe vera supplement Nutrition 0.000 description 1
- 229940087168 alpha tocopherol Drugs 0.000 description 1
- HDTRYLNUVZCQOY-LIZSDCNHSA-N alpha,alpha-trehalose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-LIZSDCNHSA-N 0.000 description 1
- TUFYVOCKVJOUIR-UHFFFAOYSA-N alpha-Thujaplicin Natural products CC(C)C=1C=CC=CC(=O)C=1O TUFYVOCKVJOUIR-UHFFFAOYSA-N 0.000 description 1
- AWUCVROLDVIAJX-UHFFFAOYSA-N alpha-glycerophosphate Natural products OCC(O)COP(O)(O)=O AWUCVROLDVIAJX-UHFFFAOYSA-N 0.000 description 1
- 150000001408 amides Chemical class 0.000 description 1
- 230000003712 anti-aging effect Effects 0.000 description 1
- 230000002280 anti-androgenic effect Effects 0.000 description 1
- 239000000051 antiandrogen Substances 0.000 description 1
- 239000002246 antineoplastic agent Substances 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 230000003078 antioxidant effect Effects 0.000 description 1
- 235000006708 antioxidants Nutrition 0.000 description 1
- 239000010477 apricot oil Substances 0.000 description 1
- 229960000271 arbutin Drugs 0.000 description 1
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 description 1
- 229960005070 ascorbic acid Drugs 0.000 description 1
- 229940009098 aspartate Drugs 0.000 description 1
- 235000021302 avocado oil Nutrition 0.000 description 1
- 239000008163 avocado oil Substances 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- 229960002685 biotin Drugs 0.000 description 1
- 235000020958 biotin Nutrition 0.000 description 1
- 239000011616 biotin Substances 0.000 description 1
- 239000007844 bleaching agent Substances 0.000 description 1
- 229920001400 block copolymer Polymers 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 229940116229 borneol Drugs 0.000 description 1
- FAPWYRCQGJNNSJ-UBKPKTQASA-L calcium D-pantothenic acid Chemical compound [Ca+2].OCC(C)(C)[C@@H](O)C(=O)NCCC([O-])=O.OCC(C)(C)[C@@H](O)C(=O)NCCC([O-])=O FAPWYRCQGJNNSJ-UBKPKTQASA-L 0.000 description 1
- 229960002079 calcium pantothenate Drugs 0.000 description 1
- 239000010495 camellia oil Substances 0.000 description 1
- 235000017663 capsaicin Nutrition 0.000 description 1
- 229960002504 capsaicin Drugs 0.000 description 1
- 229940008396 carrot extract Drugs 0.000 description 1
- 239000005018 casein Substances 0.000 description 1
- BECPQYXYKAMYBN-UHFFFAOYSA-N casein, tech. Chemical compound NCCCCC(C(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(CC(C)C)N=C(O)C(CCC(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(C(C)O)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(COP(O)(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(N)CC1=CC=CC=C1 BECPQYXYKAMYBN-UHFFFAOYSA-N 0.000 description 1
- 235000021240 caseins Nutrition 0.000 description 1
- 235000019318 cassia gum Nutrition 0.000 description 1
- 229940119217 chamomile extract Drugs 0.000 description 1
- DERZBLKQOCDDDZ-JLHYYAGUSA-N cinnarizine Chemical compound C1CN(C(C=2C=CC=CC=2)C=2C=CC=CC=2)CCN1C\C=C\C1=CC=CC=C1 DERZBLKQOCDDDZ-JLHYYAGUSA-N 0.000 description 1
- 229960000876 cinnarizine Drugs 0.000 description 1
- 239000012459 cleaning agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 238000009833 condensation Methods 0.000 description 1
- 230000005494 condensation Effects 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- 239000008271 cosmetic emulsion Substances 0.000 description 1
- 239000001599 crocus sativus l. flower extract Substances 0.000 description 1
- 150000005690 diesters Chemical class 0.000 description 1
- ZBCBWPMODOFKDW-UHFFFAOYSA-N diethanolamine Chemical compound OCCNCCO ZBCBWPMODOFKDW-UHFFFAOYSA-N 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- KCIDZIIHRGYJAE-YGFYJFDDSA-L dipotassium;[(2r,3r,4s,5r,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] phosphate Chemical compound [K+].[K+].OC[C@H]1O[C@H](OP([O-])([O-])=O)[C@H](O)[C@@H](O)[C@H]1O KCIDZIIHRGYJAE-YGFYJFDDSA-L 0.000 description 1
- KPUWHANPEXNPJT-UHFFFAOYSA-N disiloxane Chemical class [SiH3]O[SiH3] KPUWHANPEXNPJT-UHFFFAOYSA-N 0.000 description 1
- 239000003995 emulsifying agent Substances 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 229960002061 ergocalciferol Drugs 0.000 description 1
- 150000002148 esters Chemical class 0.000 description 1
- TVQGDYNRXLTQAP-UHFFFAOYSA-N ethyl heptanoate Chemical compound CCCCCCC(=O)OCC TVQGDYNRXLTQAP-UHFFFAOYSA-N 0.000 description 1
- 235000008524 evening primrose extract Nutrition 0.000 description 1
- 239000010475 evening primrose oil Substances 0.000 description 1
- 229940089020 evening primrose oil Drugs 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 239000003205 fragrance Substances 0.000 description 1
- 229930182830 galactose Natural products 0.000 description 1
- FODTZLFLDFKIQH-FSVGXZBPSA-N gamma-Oryzanol (TN) Chemical compound C1=C(O)C(OC)=CC(\C=C\C(=O)O[C@@H]2C([C@@H]3CC[C@H]4[C@]5(C)CC[C@@H]([C@@]5(C)CC[C@@]54C[C@@]53CC2)[C@H](C)CCC=C(C)C)(C)C)=C1 FODTZLFLDFKIQH-FSVGXZBPSA-N 0.000 description 1
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 description 1
- 235000020706 garlic extract Nutrition 0.000 description 1
- 238000001879 gelation Methods 0.000 description 1
- 229940002508 ginger extract Drugs 0.000 description 1
- 235000020708 ginger extract Nutrition 0.000 description 1
- 235000020710 ginseng extract Nutrition 0.000 description 1
- 239000000174 gluconic acid Substances 0.000 description 1
- 235000012208 gluconic acid Nutrition 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 229930195712 glutamate Natural products 0.000 description 1
- LPLVUJXQOOQHMX-UHFFFAOYSA-N glycyrrhetinic acid glycoside Natural products C1CC(C2C(C3(CCC4(C)CCC(C)(CC4C3=CC2=O)C(O)=O)C)(C)CC2)(C)C2C(C)(C)C1OC1OC(C(O)=O)C(O)C(O)C1OC1OC(C(O)=O)C(O)C(O)C1O LPLVUJXQOOQHMX-UHFFFAOYSA-N 0.000 description 1
- 239000001685 glycyrrhizic acid Substances 0.000 description 1
- 229960004949 glycyrrhizic acid Drugs 0.000 description 1
- UYRUBYNTXSDKQT-UHFFFAOYSA-N glycyrrhizic acid Natural products CC1(C)C(CCC2(C)C1CCC3(C)C2C(=O)C=C4C5CC(C)(CCC5(C)CCC34C)C(=O)O)OC6OC(C(O)C(O)C6OC7OC(O)C(O)C(O)C7C(=O)O)C(=O)O UYRUBYNTXSDKQT-UHFFFAOYSA-N 0.000 description 1
- 235000019410 glycyrrhizin Nutrition 0.000 description 1
- LPLVUJXQOOQHMX-QWBHMCJMSA-N glycyrrhizinic acid Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@@H]1C([C@H]2[C@]([C@@H]3[C@@]([C@@]4(CC[C@@]5(C)CC[C@@](C)(C[C@H]5C4=CC3=O)C(O)=O)C)(C)CC2)(C)CC1)(C)C)C(O)=O)[C@@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O LPLVUJXQOOQHMX-QWBHMCJMSA-N 0.000 description 1
- 229940038487 grape extract Drugs 0.000 description 1
- 238000009499 grossing Methods 0.000 description 1
- 239000010440 gypsum Substances 0.000 description 1
- 229910052602 gypsum Inorganic materials 0.000 description 1
- 239000012676 herbal extract Substances 0.000 description 1
- VVIUBCNYACGLLV-UHFFFAOYSA-N hypotaurine Chemical compound [NH3+]CCS([O-])=O VVIUBCNYACGLLV-UHFFFAOYSA-N 0.000 description 1
- 230000001771 impaired effect Effects 0.000 description 1
- 229960005436 inositol nicotinate Drugs 0.000 description 1
- 229940119170 jojoba wax Drugs 0.000 description 1
- 108010028309 kalinin Proteins 0.000 description 1
- BEJNERDRQOWKJM-UHFFFAOYSA-N kojic acid Chemical compound OCC1=CC(=O)C(O)=CO1 BEJNERDRQOWKJM-UHFFFAOYSA-N 0.000 description 1
- 229960004705 kojic acid Drugs 0.000 description 1
- WZNJWVWKTVETCG-UHFFFAOYSA-N kojic acid Natural products OC(=O)C(N)CN1C=CC(=O)C(O)=C1 WZNJWVWKTVETCG-UHFFFAOYSA-N 0.000 description 1
- 229940039717 lanolin Drugs 0.000 description 1
- 235000019388 lanolin Nutrition 0.000 description 1
- 235000021374 legumes Nutrition 0.000 description 1
- 229940069445 licorice extract Drugs 0.000 description 1
- 239000000711 locust bean gum Substances 0.000 description 1
- 235000010420 locust bean gum Nutrition 0.000 description 1
- 229910001629 magnesium chloride Inorganic materials 0.000 description 1
- 239000002075 main ingredient Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 description 1
- AHXDSVSZEZHDLV-UHFFFAOYSA-N mesulfen Chemical compound CC1=CC=C2SC3=CC(C)=CC=C3SC2=C1 AHXDSVSZEZHDLV-UHFFFAOYSA-N 0.000 description 1
- 229960005479 mesulfen Drugs 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- QAHLFXYLXBBCPS-IZEXYCQBSA-N methyl n-[(2s)-1-[[(5s)-5-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-6-hydroxyhexyl]amino]-1-oxo-3,3-diphenylpropan-2-yl]carbamate Chemical compound C=1C=CC=CC=1C([C@H](NC(=O)OC)C(=O)NCCCC[C@@H](CO)N(CC(C)C)S(=O)(=O)C=1C=CC(N)=CC=1)C1=CC=CC=C1 QAHLFXYLXBBCPS-IZEXYCQBSA-N 0.000 description 1
- 239000000693 micelle Substances 0.000 description 1
- 230000001333 moisturizer Effects 0.000 description 1
- MFZCIDXOLLEMOO-GYSGTQPESA-N myo-inositol hexanicotinate Chemical compound O([C@H]1[C@@H]([C@H]([C@@H](OC(=O)C=2C=NC=CC=2)[C@@H](OC(=O)C=2C=NC=CC=2)[C@@H]1OC(=O)C=1C=NC=CC=1)OC(=O)C=1C=NC=CC=1)OC(=O)C=1C=NC=CC=1)C(=O)C1=CC=CN=C1 MFZCIDXOLLEMOO-GYSGTQPESA-N 0.000 description 1
- JXTPJDDICSTXJX-UHFFFAOYSA-N n-Triacontane Natural products CCCCCCCCCCCCCCCCCCCCCCCCCCCCCC JXTPJDDICSTXJX-UHFFFAOYSA-N 0.000 description 1
- 125000001400 nonyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 239000010466 nut oil Substances 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 239000004006 olive oil Substances 0.000 description 1
- 235000008390 olive oil Nutrition 0.000 description 1
- BJRNKVDFDLYUGJ-UHFFFAOYSA-N p-hydroxyphenyl beta-D-alloside Natural products OC1C(O)C(O)C(CO)OC1OC1=CC=C(O)C=C1 BJRNKVDFDLYUGJ-UHFFFAOYSA-N 0.000 description 1
- 239000003002 pH adjusting agent Substances 0.000 description 1
- 235000019161 pantothenic acid Nutrition 0.000 description 1
- 150000002948 pantothenic acids Chemical class 0.000 description 1
- 229920000570 polyether Polymers 0.000 description 1
- 238000006116 polymerization reaction Methods 0.000 description 1
- 239000001103 potassium chloride Substances 0.000 description 1
- 235000011164 potassium chloride Nutrition 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 230000002335 preservative effect Effects 0.000 description 1
- RADKZDMFGJYCBB-UHFFFAOYSA-N pyridoxal hydrochloride Natural products CC1=NC=C(CO)C(C=O)=C1O RADKZDMFGJYCBB-UHFFFAOYSA-N 0.000 description 1
- 229960004172 pyridoxine hydrochloride Drugs 0.000 description 1
- 235000019171 pyridoxine hydrochloride Nutrition 0.000 description 1
- 239000011764 pyridoxine hydrochloride Substances 0.000 description 1
- 238000003908 quality control method Methods 0.000 description 1
- 235000020944 retinol Nutrition 0.000 description 1
- 239000011607 retinol Substances 0.000 description 1
- 229960003471 retinol Drugs 0.000 description 1
- 229960000342 retinol acetate Drugs 0.000 description 1
- 235000019173 retinyl acetate Nutrition 0.000 description 1
- 239000011770 retinyl acetate Substances 0.000 description 1
- QGNJRVVDBSJHIZ-QHLGVNSISA-N retinyl acetate Chemical compound CC(=O)OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C QGNJRVVDBSJHIZ-QHLGVNSISA-N 0.000 description 1
- 235000019192 riboflavin Nutrition 0.000 description 1
- 239000002151 riboflavin Substances 0.000 description 1
- 239000010667 rosehip oil Substances 0.000 description 1
- 229940092258 rosemary extract Drugs 0.000 description 1
- 235000020748 rosemary extract Nutrition 0.000 description 1
- 239000001233 rosmarinus officinalis l. extract Substances 0.000 description 1
- 229940109850 royal jelly Drugs 0.000 description 1
- IKGXIBQEEMLURG-NVPNHPEKSA-N rutin Chemical compound O[C@@H]1[C@H](O)[C@@H](O)[C@H](C)O[C@H]1OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@H](OC=2C(C3=C(O)C=C(O)C=C3OC=2C=2C=C(O)C(O)=CC=2)=O)O1 IKGXIBQEEMLURG-NVPNHPEKSA-N 0.000 description 1
- 235000005713 safflower oil Nutrition 0.000 description 1
- 239000003813 safflower oil Substances 0.000 description 1
- 229940076591 saffron extract Drugs 0.000 description 1
- 229940112950 sage extract Drugs 0.000 description 1
- 235000020752 sage extract Nutrition 0.000 description 1
- 229940058287 salicylic acid derivative anticestodals Drugs 0.000 description 1
- 150000003872 salicylic acid derivatives Chemical class 0.000 description 1
- 238000005185 salting out Methods 0.000 description 1
- 239000003352 sequestering agent Substances 0.000 description 1
- 239000008159 sesame oil Substances 0.000 description 1
- 235000011803 sesame oil Nutrition 0.000 description 1
- 239000000377 silicon dioxide Substances 0.000 description 1
- 239000001509 sodium citrate Substances 0.000 description 1
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 description 1
- 229960001790 sodium citrate Drugs 0.000 description 1
- 235000011083 sodium citrates Nutrition 0.000 description 1
- 235000019983 sodium metaphosphate Nutrition 0.000 description 1
- 235000019830 sodium polyphosphate Nutrition 0.000 description 1
- 229910052938 sodium sulfate Inorganic materials 0.000 description 1
- 229940032094 squalane Drugs 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 125000001424 substituent group Chemical group 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 235000000346 sugar Nutrition 0.000 description 1
- 150000005846 sugar alcohols Polymers 0.000 description 1
- 150000008163 sugars Chemical class 0.000 description 1
- 239000011593 sulfur Substances 0.000 description 1
- 229910052717 sulfur Inorganic materials 0.000 description 1
- 239000002600 sunflower oil Substances 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 235000015523 tannic acid Nutrition 0.000 description 1
- LRBQNJMCXXYXIU-NRMVVENXSA-N tannic acid Chemical compound OC1=C(O)C(O)=CC(C(=O)OC=2C(=C(O)C=C(C=2)C(=O)OC[C@@H]2[C@H]([C@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)[C@@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)[C@@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)O2)OC(=O)C=2C=C(OC(=O)C=3C=C(O)C(O)=C(O)C=3)C(O)=C(O)C=2)O)=C1 LRBQNJMCXXYXIU-NRMVVENXSA-N 0.000 description 1
- 229940033123 tannic acid Drugs 0.000 description 1
- 229920002258 tannic acid Polymers 0.000 description 1
- 239000000213 tara gum Substances 0.000 description 1
- 235000010491 tara gum Nutrition 0.000 description 1
- 229940104261 taurate Drugs 0.000 description 1
- XOAAWQZATWQOTB-UHFFFAOYSA-N taurine Chemical compound NCCS(O)(=O)=O XOAAWQZATWQOTB-UHFFFAOYSA-N 0.000 description 1
- 229940092665 tea leaf extract Drugs 0.000 description 1
- 239000002562 thickening agent Substances 0.000 description 1
- SHWIJIJNPFXOFS-UHFFFAOYSA-N thiotaurine Chemical compound NCCS(O)(=O)=S SHWIJIJNPFXOFS-UHFFFAOYSA-N 0.000 description 1
- 229940098465 tincture Drugs 0.000 description 1
- 229960000984 tocofersolan Drugs 0.000 description 1
- 229950009883 tocopheryl nicotinate Drugs 0.000 description 1
- JIVZKJJQOZQXQB-UHFFFAOYSA-N tolazoline Chemical compound C=1C=CC=CC=1CC1=NCCN1 JIVZKJJQOZQXQB-UHFFFAOYSA-N 0.000 description 1
- 229960002312 tolazoline Drugs 0.000 description 1
- 108010021724 tonin Proteins 0.000 description 1
- GYDJEQRTZSCIOI-LJGSYFOKSA-N tranexamic acid Chemical compound NC[C@H]1CC[C@H](C(O)=O)CC1 GYDJEQRTZSCIOI-LJGSYFOKSA-N 0.000 description 1
- 229960000401 tranexamic acid Drugs 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 235000001019 trigonella foenum-graecum Nutrition 0.000 description 1
- 229960005066 trisodium edetate Drugs 0.000 description 1
- 239000008513 turmeric extract Substances 0.000 description 1
- 229940052016 turmeric extract Drugs 0.000 description 1
- 235000020240 turmeric extract Nutrition 0.000 description 1
- 229960001722 verapamil Drugs 0.000 description 1
- 235000019155 vitamin A Nutrition 0.000 description 1
- 239000011719 vitamin A Substances 0.000 description 1
- 235000019164 vitamin B2 Nutrition 0.000 description 1
- 239000011716 vitamin B2 Substances 0.000 description 1
- 235000019158 vitamin B6 Nutrition 0.000 description 1
- 239000011726 vitamin B6 Substances 0.000 description 1
- 235000019154 vitamin C Nutrition 0.000 description 1
- 239000011718 vitamin C Substances 0.000 description 1
- 235000019166 vitamin D Nutrition 0.000 description 1
- 239000011710 vitamin D Substances 0.000 description 1
- 150000003710 vitamin D derivatives Chemical class 0.000 description 1
- MECHNRXZTMCUDQ-RKHKHRCZSA-N vitamin D2 Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)/C=C/[C@H](C)C(C)C)=C\C=C1\C[C@@H](O)CCC1=C MECHNRXZTMCUDQ-RKHKHRCZSA-N 0.000 description 1
- 235000001892 vitamin D2 Nutrition 0.000 description 1
- 239000011653 vitamin D2 Substances 0.000 description 1
- 235000005282 vitamin D3 Nutrition 0.000 description 1
- 239000011647 vitamin D3 Substances 0.000 description 1
- QYSXJUFSXHHAJI-YRZJJWOYSA-N vitamin D3 Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C\C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-YRZJJWOYSA-N 0.000 description 1
- 229940046009 vitamin E Drugs 0.000 description 1
- 235000019165 vitamin E Nutrition 0.000 description 1
- 239000011709 vitamin E Substances 0.000 description 1
- 229940045997 vitamin a Drugs 0.000 description 1
- 229940011671 vitamin b6 Drugs 0.000 description 1
- 229940046008 vitamin d Drugs 0.000 description 1
- 229940021056 vitamin d3 Drugs 0.000 description 1
- 229920003169 water-soluble polymer Polymers 0.000 description 1
- 239000010497 wheat germ oil Substances 0.000 description 1
- 239000000811 xylitol Substances 0.000 description 1
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 description 1
- 229960002675 xylitol Drugs 0.000 description 1
- 235000010447 xylitol Nutrition 0.000 description 1
- 239000009538 yokuinin Substances 0.000 description 1
- OJYLAHXKWMRDGS-UHFFFAOYSA-N zingerone Chemical compound COC1=CC(CCC(C)=O)=CC=C1O OJYLAHXKWMRDGS-UHFFFAOYSA-N 0.000 description 1
- 235000004835 α-tocopherol Nutrition 0.000 description 1
- 239000002076 α-tocopherol Substances 0.000 description 1
- 229930007845 β-thujaplicin Natural products 0.000 description 1
Landscapes
- Cosmetics (AREA)
Abstract
Description
本発明は、軽いふわふわの泡質を維持し、望まれる粘度を維持した上に、洗髪からすすぎまでの滑らかさ、指通り性を向上させ、乾燥時においても髪の指通り性、まとまり感、柔らかさ、ハリコシ感等のコンディショニング効果を発現できる毛髪洗浄剤組成物に関する。 The present invention maintains a light and fluffy foam quality, maintains the desired viscosity, improves the smoothness from hair washing to rinsing, and the fingering property, and even when dry, the fingering property of the hair, the feeling of unity, The present invention relates to a hair cleansing composition capable of expressing conditioning effects such as softness and harshness.
近年、髪を洗髪するとき、クリーミィーで重い泡より、軽くふわふわの泡の方が支持されている。
一般的に毛髪洗浄剤組成物にノニオン活性剤を配合すると泡質がクリーミィーになる事が知られており、軽くふわふわの泡質を実現させるために、あえてノニオン活性剤を配合しなかったり、配合量を抑えた処方が増えてきている。さらに、ジエタノールアミンの問題もあり、ノニオン活性剤低配合、無配合処方が望まれている。
In recent years, when washing hair, lighter and softer foams are supported than creamy and heavy foams.
In general, it is known that the foam quality becomes creamy when a nonionic active agent is added to the hair cleansing composition, and in order to achieve a light and fluffy foam quality, the nonionic active agent is not intentionally added. Prescriptions with reduced amounts are increasing. Furthermore, there is also a problem of diethanolamine, and a low nonionic active compounding and non-compounding formulation is desired.
しかしながら、ノニオン活性剤の配合量を抑えると、軽くふわふわの泡質にはなるが製品粘度が出にくく、増粘目的で両性界面活性剤／アニオン界面活性剤の併用や増粘性水溶性ポリマーの添加、塩を加える事で粘度をコントロールしている。それらの既知技術の積み重ねにより、軽くふわふわした泡質で、適度な粘度を出す毛髪洗浄剤を調整することは可能であるが、洗髪からすすぎ時の指通り、乾燥後までの髪の滑らかさは不十分で使用感の悪い物になる。特に傷んだ髪では洗い難い性能となる。 However, if the amount of the nonionic active agent is reduced, the foam becomes light and fluffy, but the product viscosity is difficult to be obtained. For the purpose of thickening, the amphoteric surfactant / anionic surfactant is used together or the addition of a thickening water-soluble polymer is added. The viscosity is controlled by adding salt. By accumulating these known technologies, it is possible to adjust a hair cleanser that has a light, fluffy foam quality and an appropriate viscosity, but the smoothness of hair from after washing to after rinsing and after drying Insufficient and unusable. Especially, it is difficult to wash with damaged hair.
洗髪からすすぎまでの滑らかさ、指通り性を向上させる目的で、カチオン性高分子を代表とするコンディショニング剤を配合すること開示されている（特許文献１〜２）。
ところで、毛髪洗浄剤組成物の多くは、塗布工程中に毛髪上にコンディショニング剤を十分に付着させない。
塗布工程中にコンディショニング剤の大部分が洗い落とされてしまうため、コンディショニング剤による恩恵はほとんど又は全く得られない。これらの問題を解決するため、近年のシャンプーでは、コンディショニング剤としてカチオン性高分子を配合し、これとアニオン性界面活性剤、両性界面活性剤から形成される複合体が析出するコアセルベーション現象によって、すすぎ時および乾燥後の滑らかさを付与している（特許文献３）。
For the purpose of improving the smoothness from shampooing to rinsing and fingering, it is disclosed that a conditioning agent represented by a cationic polymer is blended (Patent Documents 1 and 2).
By the way, many hair-cleaning agent compositions do not fully adhere a conditioning agent on hair during an application | coating process.
Little or no benefit from the conditioning agent is obtained because the majority of the conditioning agent is washed away during the application process. In order to solve these problems, in recent shampoos, a cationic polymer is blended as a conditioning agent, and a coacervation phenomenon in which a complex formed from this, an anionic surfactant and an amphoteric surfactant is precipitated. Smoothness is imparted at the time of rinsing and after drying (Patent Document 3).
しかしながら、この方法はノニオン成分であるアルキレンオキシド誘導体をコアセルベーション形成促進剤として必須成分としており、上記したとおり、ノニオン活性剤の増量は泡質が変わってしまう。 However, this method uses an alkylene oxide derivative, which is a nonionic component, as an essential component as a coacervation formation accelerator, and as described above, increasing the amount of the nonionic active agent changes the foam quality.
カチオン化グァーガムは、従来より使用されているカチオン性高分子の一種であり、Ｎーアシルアミノ酸との併用系に関しては、既に研究されている。（特許文献１〜３）
しかしながら、これらの検討は、界面活性剤の主剤としてＮ−アシルアミノ酸を用いたシャンプー組成物の改質を目的としているものであり、アルキルエーテルサルフェート＋両性界面活性剤＋カチオン化グァーガムを配合したシャンプーに一定量のＮ−アシルアミノ酸を添加した系の検討はなされていない。
Cationized guar gum is a kind of cationic polymer that has been used conventionally, and a combined system with N-acylamino acid has already been studied. (Patent Documents 1 to 3)
However, these studies are aimed at modifying a shampoo composition using an N-acylamino acid as a main component of a surfactant, and a shampoo containing alkyl ether sulfate + amphoteric surfactant + cationized guar gum. A system in which a certain amount of N-acylamino acid has been added to is not studied.
これら従来技術の毛髪洗浄剤組成物には、軽いふわふわの泡質を維持し、望まれる粘度を維持した上に、洗髪からすすぎまでの滑らかさ、指通り性を向上させる目的を両立できていない。
即ち、現在に至るまで充分満足できる毛髪洗浄剤組成物は開発されていない。
These conventional hair cleanser compositions maintain a light, fluffy foam quality, maintain the desired viscosity, and are not compatible with the purpose of improving the smoothness from fingering to rinsing and fingering. .
That is, until now, no satisfactory hair cleansing composition has been developed.
本発明者は、軽いふわふわの泡質を維持し、望まれる粘度を維持した上に、洗髪からすすぎまでの滑らかさ、指通り性を向上させるため、鋭意検討した結果、アルキルエーテルサルフェート＋両性界面活性剤＋カチオン化ガラクトマンナンを配合したシャンプーに、一定量のＮ−アシル−Ｎ−メチル−β−アラニンを添加する事で解決できる事を見出し本発明に至った。 As a result of intensive studies to maintain the light and fluffy foam quality, maintain the desired viscosity, and improve smoothness from hair washing to rinsing and fingering, as a result of alkyl ether sulfate + amphoteric interface The present inventors have found that this can be solved by adding a certain amount of N-acyl-N-methyl-β-alanine to a shampoo containing activator + cationized galactomannan.
即ち、本発明は、
（Ａ）アルキルエーテルサルフェート型アニオン界面活性剤 ８．０〜２０．０質量％
（Ｂ）一般式（１）で示される特定の両性又は双性界面活性剤 １．０〜５．０重量％
Ｒ１はsが１の時、炭素数７〜２１の炭化水素鎖を示し、それらの混合物でも良く、
Ｒ１はsが０の時、炭素数８〜２２の炭化水素鎖を示し、それらの混合物でも良い。
Ｒ２は炭素数１〜３のアルキレン基であり、水酸基が結合されていても良い。
Ｑ−は−ＣＯＯ−基、乃至は−ＳＯ３ −基を示す。］
（Ｃ）カチオン化ガラクトマンナン ０．２〜１．０重量％
（Ｄ）Ｎ−アシル−Ｎ−メチル−β−アラニン塩 ０．２〜２．０重量％
（Ｅ）中性無機塩 ０．１〜３．０重量％
（Ｆ）脂肪酸ジエタノールアミドを実質的に含有しないノニオン性界面活性剤を１．０重量％以下
（Ｇ）精製水 残分（組成物全体を１００重量％とする量）を含有する毛髪洗浄剤組成物に関する。
That is, the present invention
(A) Alkyl ether sulfate type anionic surfactant 8.0 to 20.0% by mass
(B) Specific amphoteric or zwitterionic surfactant represented by general formula (1) 1.0 to 5.0% by weight
R 1 represents a hydrocarbon chain having 7 to 21 carbon atoms when s is 1, and may be a mixture thereof.
R 1 represents a hydrocarbon chain having 8 to 22 carbon atoms when s is 0, and may be a mixture thereof.
R 2 is an alkylene group having 1 to 3 carbon atoms, and a hydroxyl group may be bonded thereto.
Q - is -COO - group, or is -SO 3 - a group. ]
(C) Cationized galactomannan 0.2 to 1.0% by weight
(D) N-acyl-N-methyl-β-alanine salt 0.2 to 2.0% by weight
(E) Neutral inorganic salt 0.1 to 3.0% by weight
(F) A hair cleansing composition containing 1.0% by weight or less of a nonionic surfactant substantially free from fatty acid diethanolamide (G) a residue of purified water (amount that makes the entire composition 100% by weight) Related to things.
カチオン化ガラクトマンナンとしてはカチオン化グァーを使用することがより好ましい。 It is more preferable to use a cationized guar as the cationized galactomannan.
副コンディショニング剤として、各種シリコーン、シリコーン誘導体及び毛髪ダメージケアケア効果のある油剤から選ばれる少なくとも１種を含有することがより好ましい。 As the auxiliary conditioning agent, it is more preferable to contain at least one selected from various silicones, silicone derivatives, and oil agents having a hair damage care care effect.
本発明、毛髪洗浄剤組成物により、軽いふわふわの泡質を維持し、望まれる粘度を維持した上に、洗髪からすすぎまでの滑らかさ、指通り性を向上させ、乾燥時においても髪の指通り性、まとまり感、柔らかさ、ハリコシ感等のコンディショニング効果を付与することができる。 The hair cleansing composition of the present invention maintains a light and fluffy foam quality, maintains the desired viscosity, improves the smoothness from hair washing to rinsing, and improves the fingering property. Conditioning effects such as street, unity, softness, and firmness can be imparted.
以下、本発明の実施形態について説明する。
本発明毛髪洗浄剤組成物のＡ成分はアルキルエーテルサルフェートである。起泡性、粘度構築の要になる本発明毛髪洗浄剤組成物の主剤である。本発明の求める軽いふわふわの泡質を考慮すると、エチレンオキサイド1モル付加品が特に望ましい。本発明毛髪洗浄剤組成物においてアルキルエーテルサルフェートは、８．０〜２０．０重量％配合されるが、８．０重量％未満の配合量では、極端に起泡力が落ちるため好ましくなく、２０．０重量％を超えて配合された場合、他成分との組み合わせによりゲル化が発生するなどの問題があり好ましくない。最適配合量としては起泡量、系の粘度安定性を考え１０重量％以上配合することがより好ましい。
アルキルエーテルサルフェートは広く流通しており、エチレンオキサイド１モル付加体を中心に所有するアルキルエーテルサルフェートとしては、エマール１７０Ｊ（花王社製）が挙げられる。
Hereinafter, embodiments of the present invention will be described.
The A component of the hair cleansing composition of the present invention is an alkyl ether sulfate. This is the main ingredient of the hair cleansing composition of the present invention which is essential for foaming and viscosity building. In consideration of the light and fluffy foam quality required by the present invention, an ethylene oxide 1 mol addition product is particularly desirable. In the hair cleansing composition of the present invention, the alkyl ether sulfate is blended in an amount of 8.0 to 20.0% by weight. However, if the blending amount is less than 8.0% by weight, the foaming power is extremely lowered. If the blending amount exceeds 0.0% by weight, there is a problem that gelation occurs due to the combination with other components, which is not preferable. The optimum blending amount is more preferably 10% by weight or more in consideration of the amount of foaming and the viscosity stability of the system.
Alkyl ether sulfate is widely distributed, and an example of an alkyl ether sulfate mainly owned by an ethylene oxide 1-mol adduct is EMAL 170J (manufactured by Kao Corporation).
本発明毛髪洗浄剤組成物のＢ成分は一般式（１）で示される特定の両性又は双性界面活性剤である。
Ｒ１はsが１の時、炭素数７〜２１の炭化水素鎖を示し、それらの混合物でも良く、
Ｒ１はsが０の時、炭素数８〜２２の炭化水素鎖を示し、それらの混合物でも良い。
Ｒ２は炭素数１〜３のアルキレン基であり、水酸基が結合されていても良い。
Ｑ−は−ＣＯＯ−基、乃至は−ＳＯ３ −基を示す。］
Ｂ成分である一般式（１）で示される特定の両性又は双性界面活性剤は広く流通しており、具体例としては、
ソフタゾリンＣＰＢ，ソフタゾリンＬＰＢ，ソフタゾリンＬＳＢ，ソフタゾリンＣＰＢ−Ｒ，ソフタゾリンＬＰＢ−Ｒ，ソフタゾリンＰＫＰＢ，ソフタゾリンＬＳＢ−Ｒ（川研ファインケミカル社製），アンヒトール２０ＡＢ，アンヒトール２０ＢＳ，アンヒトール２４Ｂ，アンヒトール５５ＡＢ，アンヒトール８６Ｂ，アンヒトール２０ＨＤ（花王株式会社製）等が挙げられる。
Component B of the hair cleansing composition of the present invention is a specific amphoteric or amphoteric surfactant represented by the general formula (1).
R 1 represents a hydrocarbon chain having 7 to 21 carbon atoms when s is 1, and may be a mixture thereof.
R 1 represents a hydrocarbon chain having 8 to 22 carbon atoms when s is 0, and may be a mixture thereof.
R 2 is an alkylene group having 1 to 3 carbon atoms, and a hydroxyl group may be bonded thereto.
Q - is -COO - group, or is -SO 3 - a group. ]
The specific amphoteric or zwitterionic surfactant represented by the general formula (1) as the B component is widely distributed. As a specific example,
Softazolin CPB, Softazolin LPB, Softazolin LSB, Softazolin CPB-R, Softazolin LPB-R, Softazolin PKPB, Softazolin LSB-R (manufactured by Kawaken Fine Chemicals), Amphital 20AB, Amphithr 20BS, Amphithr 24B, Amphithr 55AB, Amphithr 86B 20HD (manufactured by Kao Corporation) and the like.
Ｂ成分は本発明毛髪洗浄剤組成物において１〜５重量％配合される。系の粘度構築の為２重量％以上の配合が好ましい。５重量％を超えて配合されると泡質に影響を与え、本発明の目指す「軽いふわふわの泡質」を実現できなくなリ、泡質がクリーミーになるため好ましくない。 B component is mix | blended 1-5 weight% in this invention hair cleansing composition. In order to build the viscosity of the system, a blending amount of 2% by weight or more is preferable. If the blending amount exceeds 5% by weight, the foam quality is affected, and the “light fluffy foam quality” aimed at by the present invention cannot be realized.
本発明毛髪洗浄剤組成物のＣ成分はカチオン化ガラクトマンナンである。カチオン化ガラクトマンナンは、ガラクトマンナンをカチオン化することにより得られる。ガラクトマンナンは．ガテクトースとマンノースを構成糖とする中性の水溶性植物ヘテロ多糖類の総称で．とくにマメ科植物の種子に多く含まれる。マンノースとガテクトースの縮合様式は．マンノースがβ−1,4結合によって直線的につながったβマンナンの主鎖骨格にガラグトースが置換基としてα−1,6結合した短鎖分岐構造を持つ。 The C component of the hair cleansing composition of the present invention is cationized galactomannan. Cationized galactomannan is obtained by cationizing galactomannan. Galactomannan is. A generic term for neutral water-soluble plant heteropolysaccharides composed of gaectose and mannose. It is especially abundant in legume seeds. What is the condensation mode of mannose and gaectose? The main chain skeleton of β-mannan, in which mannose is linearly connected by β-1,4 bonds, has a short-chain branching structure in which galactose is α-1,6-linked as a substituent.
Ｃ成分であるカチオン化ガラクトマンナンは、本発明毛髪洗浄剤組成物の粘度構築に作用すると同時にカチオン性高分子であり、すすぎ時の指通りや乾燥後の滑らかさを向上させるために配合される。成分Ｃは、成分Ａ、成分Ｂ及び成分Ｄの混合ミセルと複合体を形成し、すすぎ時の希釈によって系内から析出（コアセルベーション現象）し、これが毛髪に吸着することで、すすぎ時の指通りや乾燥後の滑らかさを向上させるコンディショニング効果を付与する。
カチオン化ガラクトマンナンの配合量は、０．２〜１．０重量％であるが、増粘を考慮すると０．３重量％以上が望ましい。カチオン化ガラクトマンナンの溶解性（安定性）を考慮すると０．８重量％以下がより望ましい。
カチオン化ガラクトマンナンとしては、カチオン化ローカストビーンガム、カチオン化グァーガム、カチオン化タラガム、カチオン化フェヌグリークガム、カチオン化カッシアガム等が挙げられるが、水性媒体への溶解ハンドリング性能よりカチオン化グァーがもっとも使いやすく好ましい。
C component cationized galactomannan is a cationic polymer that acts on the viscosity building of the hair cleansing composition of the present invention and at the same time is formulated to improve the smoothness after rinsing and after drying. . Component C forms a complex with mixed micelles of Component A, Component B and Component D, and precipitates from the system by dilution during rinsing (coacervation phenomenon), and this adsorbs to the hair, so that Provides a conditioning effect that improves smoothness after fingering and after drying.
The amount of cationized galactomannan is 0.2 to 1.0% by weight, but 0.3% by weight or more is desirable in consideration of thickening. Considering the solubility (stability) of the cationized galactomannan, 0.8% by weight or less is more desirable.
Examples of cationized galactomannans include cationized locust bean gum, cationized guar gum, cationized tara gum, cationized fenugreek gum, and cationized cassia gum. preferable.
本発明毛髪洗浄剤組成物のＤ成分は、Ｎ−アシル−Ｎ−メチル−β−アラニン塩である。Ｎ−アシル−Ｎ−メチル−β−アラニン塩はアシルアミノ酸系界面活性剤である。本発明毛髪洗浄剤組成物には０．２〜２．０重量％の配合で効果が発生する。
本発明者は、アシルアミノ酸塩添加が「アルキルエーテルサルフェート＋両性界面活性剤＋カチオン化ガラクトマンナン」基剤の毛髪洗浄剤組成物に与える影響を確認したところ、中性無機塩存在下において、アシルアミノ酸塩添加量以上の官能評価の改善が見られることを確認した。同時にＮ−アシル−Ｎ−メチル−β−アラニン塩以外のアシルアミノ酸であるアシルグルタミン酸塩、アシルアスパラギン酸塩、アシルメチルタウリン塩、アシルザルコシン塩は微量の添加でも毛髪洗浄剤組成物の粘度を大きく毀損することが分かった。Ｎ−アシル−Ｎ−メチル−β−アラニン塩の添加配合のみ２．０重量％以下の配合量では、毛髪洗浄剤組成物の粘度を毀損しないことを見出した。Ｎ−アシル−Ｎ−メチル−β−アラニン塩の添加配合量は、滑らかさ、指通り性を考えると０．５重量％以上が望ましい。粘度維持を考えると１．５重量％以下がより望ましい
Ｎ−アシル−Ｎ−メチル−β−アラニン塩の具体例としては、アラノンＡＣＥ アラノンＡＬＥ アラノンＡＬＴＡ アラノンＡＭＥ（川研ファインケミカル社製）等が挙げられる。
The D component of the hair cleansing composition of the present invention is N-acyl-N-methyl-β-alanine salt. N-acyl-N-methyl-β-alanine salt is an acylamino acid surfactant. In the hair cleansing composition of the present invention, an effect is produced at a blending amount of 0.2 to 2.0% by weight.
The present inventor confirmed the effect of the addition of acyl amino acid salt on the hair cleansing composition of the “alkyl ether sulfate + amphoteric surfactant + cationized galactomannan” base. It was confirmed that an improvement in sensory evaluation over the added amount of amino acid salt was observed. At the same time, acyl glutamate, acyl aspartate, acylmethyl taurate, and acyl sarcosine salts, which are acyl amino acids other than N-acyl-N-methyl-β-alanine salts, greatly reduce the viscosity of the hair cleaning composition even when added in a small amount. I found out that It has been found that the viscosity of the hair cleanser composition is not impaired when the amount of addition of N-acyl-N-methyl-β-alanine salt is only 2.0% by weight or less. The amount of the N-acyl-N-methyl-β-alanine salt added is preferably 0.5% by weight or more in consideration of smoothness and fingering. A specific example of N-acyl-N-methyl-β-alanine salt is more preferably 1.5% by weight or less in view of maintaining the viscosity. It is done.
本発明毛髪洗浄剤組成物のＥ成分は中性無機塩である。Ｅ成分は主にＡ成分との共働で本発明毛髪洗浄剤組成物の粘度を構築し、コアセルベーションの発生にも影響を与えていると推定される。本発明毛髪洗浄剤組成物においては０．１〜３．０重量％配合される。組成物の増粘を考えると０．３重量％以上の配合が好ましい。１．０重量％を超えて配合するとカチオン化ガラクトマンナンの種類にもよるが、ポリマーの塩析が発生するなどして好ましくない。また、Ｂ成分である特定の両性又は双性界面活性剤は、その合成の過程上食塩を複製するが、本発明のＥ成分に包含された形で中性無機塩の配合比率を計算する。 The E component of the hair cleansing composition of the present invention is a neutral inorganic salt. It is presumed that the E component mainly works with the A component to build the viscosity of the hair cleansing composition of the present invention and also affects the occurrence of coacervation. In the hair cleansing composition of the present invention, 0.1 to 3.0% by weight is blended. Considering the thickening of the composition, the blending of 0.3% by weight or more is preferable. If it exceeds 1.0% by weight, it depends on the kind of cationized galactomannan, but it is not preferable because salting out of the polymer occurs. Further, the specific amphoteric or zwitterionic surfactant which is the B component replicates sodium chloride in the process of synthesis, but calculates the blending ratio of the neutral inorganic salt in the form included in the E component of the present invention.
Ｅ成分の具体例としては、塩化ナトリウム、塩化カリウム、塩化マグネシウム等が挙げられ、これらの混合物でも良いが、入手の容易さより塩化ナトリウムを用いることが好ましい。
本発明毛髪洗浄剤組成物のＦ成分は、任意成分であり、本発明毛髪洗浄剤組成物の粘度、泡質のコントロール剤として、脂肪酸ジエタノールアミドを除くノニオン活性剤を必要に応じて配合する。
増粘効果、泡質改善効果のあるものが好ましいが、脂肪酸モノエタノールアミド グリセリルエーテル 脂肪酸多価アルコールエステル ＰＯＥアルキルエーテル（末端封鎖型含む） ＰＯＥ脂肪酸エステル（末端封鎖型含む）等が例示される。
Specific examples of the component E include sodium chloride, potassium chloride, magnesium chloride, and the like. A mixture of these may be used, but it is preferable to use sodium chloride because of its availability.
The F component of the hair cleansing composition of the present invention is an optional component, and a nonionic active agent excluding fatty acid diethanolamide is blended as necessary as a viscosity and foam quality control agent of the hair cleaning composition of the present invention.
Those having a thickening effect and foam improving effect are preferred, but fatty acid monoethanolamide glyceryl ether fatty acid polyhydric alcohol ester POE alkyl ether (including end-capped type) POE fatty acid ester (including end-capped type) and the like are exemplified.
具体的には、アミゾールＣＭＥ アミゼット２Ｃ アミゼット１ＰＣ ビスコセーフＬＭＰＥ ビスコファインＥ２Ｃ フォーマイト ２Ｅ８（川研ファインケミカル社製），アミノーンＣ−１１Ｓ（花王株式会社製），リケマールＰＬ−１００（理研ビタミン株式会社製）等が挙げられる。 Specifically, Amizole CME Amidette 2C Amidette 1PC Bisco Safe LMPE Bisco Fine E2C Format 2E8 (manufactured by Kawaken Fine Chemical Co., Ltd.), Aminone C-11S (manufactured by Kao Corporation), Riquemar PL-100 (manufactured by Riken Vitamin Co., Ltd.), etc. Is mentioned.
副コンディショニング成分を本発明毛髪洗浄剤組成物に添加すると、乾燥後の髪のまとまり向上でケア効果感が増大するため、０．１〜３．０重量％配合することが好ましい。副コンディショニング剤としては、各種シリコーン、シリコーン誘導体及び毛髪ダメージケアケア効果のある油剤を例示することができ、これらの混合物でも良い。 When a sub-conditioning component is added to the hair cleansing composition of the present invention, the care effect is increased by improving the hair unit after drying, so 0.1 to 3.0% by weight is preferably added. Examples of the auxiliary conditioning agent include various silicones, silicone derivatives, and oil agents having a hair damage care care effect, and a mixture thereof may be used.
副コンディショニング成分としてシリコーン、シリコーン誘導体に関して述べる。
シリコーン、シリコーン誘導体としては、ジメチコン、ジメチコノール、ポリエーテル変性シリコーン、アモジメチコン及びそのエマルジョンが代表的に選択される。
本発明では、ジメチコン、ジメチコノールとして、下式（２）で表される直鎖型のジメチルポリシロキサン化合物が好ましく用いられる。
As silicone and silicone derivatives, dimethicone, dimethiconol, polyether-modified silicone, amodimethicone and emulsion thereof are typically selected.
In the present invention, a linear dimethylpolysiloxane compound represented by the following formula (2) is preferably used as dimethicone and dimethiconol.
ポリエーテル変性シリコーンは、ジメチルポリシロキサンにポリエーテル変性基が導入された化合物であり、側鎖変性タイプであるペンダント型ポリエーテルシリコーン、ブロック変性タイプであるＡＢｎ型ポリエーテル変性シリコーン、末端変性タイプである末端ポリエーテル変性シリコーン等が挙げられる。ポリエーテル変性基としては、ポリオキシエチレン基、ポリオキシプロピレン基、ポリオキシエチレン・ポリオキシプロピレン基が挙げられる。具体的には、ジメチルシロキサン・メチル（ポリオキシエチレン）シロキサン・メチル（ポリオキシプロピレン）シロキサン共重合体、ジメチルシロキサン・メチル（ポリオキシエチレン）シロキサン共重合体、ジメチルシロキサン・メチル（ポリオキシプロピレン）シロキサン共重合体、ポリシロキサン−ポリオキシアルキレンブロック共重合体等が挙げられる。本発明では、側鎖変性タイプであるペンダント型ポリエーテル変性シリコーンが好ましく用いられる。 The polyether-modified silicone is a compound in which a polyether-modified group is introduced into dimethylpolysiloxane, and is a pendant-type polyether silicone that is a side chain-modified type, an ABn-type polyether-modified silicone that is a block-modified type, and a terminal-modified type. Some terminal polyether-modified silicones and the like can be mentioned. Polyether-modified groups include polyoxyethylene groups, polyoxypropylene groups, and polyoxyethylene / polyoxypropylene groups. Specifically, dimethylsiloxane / methyl (polyoxyethylene) siloxane / methyl (polyoxypropylene) siloxane copolymer, dimethylsiloxane / methyl (polyoxyethylene) siloxane copolymer, dimethylsiloxane / methyl (polyoxypropylene) Examples thereof include siloxane copolymers and polysiloxane-polyoxyalkylene block copolymers. In the present invention, a pendant polyether-modified silicone that is a side chain-modified type is preferably used.
ジメチコンとしては、ＳＨ２００シリーズ、ＢＹ１１−００７、ＢＹ１１−０２６、ＢＹ２５−３２０、ＢＹ２２−００７、ＢＹ２２−０８０、ＢＹ２２−０２９、ＢＹ２２−０５０Ａ、ＢＹ２２−０８３、ＢＹ２２−０３４、ＢＹ２２−０５５、ＢＹ２２−０６０、ＦＺ−４１５０、ＦＺ−４１８８（以上、東レ・ダウコーニング社製）、ＴＳＦ４５１シリーズ（モメンティブ・パフォーマンス・マテリアルズ・ジャパン合同会社製）、ＫＦ−９６シリーズ（信越化学工業社製）等が挙げられる。 As the dimethicone, SH200 series, BY11-007, BY11-026, BY25-320, BY22-007, BY22-080, BY22-029, BY22-050A, BY22-083, BY22-034, BY22-050, BY22-060 FZ-4150, FZ-4188 (above, manufactured by Toray Dow Corning), TSF451 series (made by Momentive Performance Materials Japan GK), KF-96 series (made by Shin-Etsu Chemical Co., Ltd.), etc. .
ジメチコノールとしては、１５０３Ｆｌｕｉｄ（東レ・ダウコーニング社製）等が挙げられる。ポリエーテル変性シリコーンとしては、ＳＳ−２８０１、ＳＳ−２８０２、ＳＳ−２８０３、ＳＳ−２８０４、ＳＳ−２８０５、ＦＺ−２２２２、ＦＺ−２２５０、ＦＺ２２３１、ＦＺ２２３３（以上、東レ・ダウコーニング社製）、ＳＩＬＳＯＦＴシリーズ、ＴＳＦ４４４０、ＴＳＦ４４４１、ＴＳＦ４４４５、ＴＳＦ４４４６、ＴＳＦ４４５２、ＴＳＦ４４６０、ＴＳＦ１１８８Ａ（以上、モメンティブ・パフォーマンス・マテリアルズ・ジャパン合同会社製）、ＫＦ−６０１１、ＫＦ−６０１５、ＫＦ−６０１２、ＫＦ−６１５Ａ、ＫＦ−９４５（以上、信越化学工業社製）等が挙げられる。 Examples of dimethiconol include 1503 Fluid (manufactured by Toray Dow Corning). Examples of the polyether-modified silicone include SS-2801, SS-2802, SS-2803, SS-2804, SS-2805, FZ-2222, FZ-2250, FZ2231, and FZ2233 (above, manufactured by Toray Dow Corning), SILSOFT. Series, TSF4440, TSF4441, TSF4445, TSF4446, TSF4452, TSF4460, TSF1188A (manufactured by Momentive Performance Materials Japan GK), KF-6011, KF-6015, KF-6012, KF-615A, KF-945 (Above, manufactured by Shin-Etsu Chemical Co., Ltd.) and the like.
アモジメチコン、アモジメチコンエマルジョンとしては、ＳＭ８９０４Ｃｏｓｍｅｔｉｃ Ｅｍｕｌｓｉｏｎ（アモジメチコン４０％含有：東レ・ダウコーニング社製）、ＳＩＬＳＴＹＬＥ ４０１（（ビスブチロキシアモジメチコン／ＰＥＧ−６０）コポリマー２１．５％含有：東レ・ダウコーニング社製）、ＳＩＬＳＴＹＬＥ １０４（（ビスイソブチルＰＥＧ−１４／アモジメチコン）コポリマー：東レ・ダウコーニング社製）、ＳＩＬＳＴＹＬＥ ２０１（（ビスイソブチルＰＥＧ−１４／アモジメチコン）コポリマー：東レ・ダウコーニング社製）が挙げられる。 As amodimethicone and amodimethicone emulsion, SM8904 Cosmetic Emulsion (containing 40% amodimethicone: manufactured by Toray Dow Corning Co., Ltd.), SILSTLE 401 ((bisbutyroxyamodimethicone / PEG-60) copolymer containing 21.5%: Toray Dow Corning), SILSTLE 104 ((bisisobutyl PEG-14 / amodimethicone) copolymer: manufactured by Toray Dow Corning), SILSTLE 201 ((bisisobutyl PEG-14 / amodimethicone) copolymer: manufactured by Toray Dow Corning) Is mentioned.
副コンディショニング成分として毛髪ダメージケア効果のある油剤に関して述べる。
毛髪ダメージケア効果のある油剤としては、分岐脂肪酸誘導体、液状植物油などが挙げられる。
An oil agent having a hair damage care effect as an auxiliary conditioning component will be described.
Examples of oil agents having a hair damage care effect include branched fatty acid derivatives and liquid vegetable oils.
液状植物油としては、マカデミアナッツ油、ホホバ油、サフラワー油、米胚芽油、小麦胚芽油、アボカド油、アルモンド油、ゴマ油、ツバキ油、ブドウ油、月見草油、シソ油、ヒマワリ油、ココナッツ油、メドフォーム油、ローズヒップ油、アプリコット油、アルガン油（アルガニアスピノザ核油）、オリーブ油およびオリーブスクワランが例示される。 Liquid vegetable oils include macadamia nut oil, jojoba oil, safflower oil, rice germ oil, wheat germ oil, avocado oil, almond oil, sesame oil, camellia oil, grape oil, evening primrose oil, perilla oil, sunflower oil, coconut oil, med Examples are foam oil, rosehip oil, apricot oil, argan oil (Arganian spinosa kernel oil), olive oil and olive squalane.
分岐脂肪酸誘導体としては、ラノリン脂肪酸、18-メチルエイコサン酸、14-メチルペンタデカン酸、14-メチルヘキサデカン酸、16-メチルヘプタデカン酸、16-メチルオクタデカン酸が挙げられる。 Examples of branched fatty acid derivatives include lanolin fatty acid, 18-methyleicosanoic acid, 14-methylpentadecanoic acid, 14-methylhexadecanoic acid, 16-methylheptadecanoic acid, and 16-methyloctadecanoic acid.
更に本発明の毛髪洗浄剤組成物には、必要に応じて、かつ本発明の効果を損なわない範囲において、通常化粧品や医薬品等の皮膚外用剤に用いられる成分、例えば、抗老化薬剤、抗炎症剤、抗アンドロゲン剤、育毛剤、保湿剤、酸化防止剤、油性成分、紫外線吸収剤、界面活性剤、増粘剤、防腐剤、アルコール類、ｐＨ調整剤、乳化剤、粉末成分、色材、水性成分、水、各種毛髪栄養剤、香料、清涼剤、生薬抽出物やビタミン類等を適宜配合することができる。 Furthermore, the hair cleansing composition of the present invention contains components that are usually used in skin external preparations such as cosmetics and pharmaceuticals, for example, anti-aging drugs, anti-inflammation, as necessary and within the range that does not impair the effects of the present invention. Agent, antiandrogen, hair restorer, moisturizer, antioxidant, oil component, UV absorber, surfactant, thickener, preservative, alcohol, pH adjuster, emulsifier, powder component, colorant, aqueous Ingredients, water, various hair nutrients, fragrances, refreshing agents, herbal extracts, vitamins, and the like can be appropriately blended.
配合できる成分の具体例を示せば、エデト酸二ナトリウム、エデト酸三ナトリウム、クエン酸ナトリウム、ポリリン酸ナトリウム、メタリン酸ナトリウム、グルコン酸等の金属封鎖剤、カフェイン、タンニン、ベラパミル、トラネキサム酸及びその誘導体、各種生薬、酢酸トコフェロール、グリチルリチン酸及びその誘導体又はその塩、グリチルレチン酸誘導体、サリチル酸誘導体、リゾフォスファチジルコリンやリゾフォスファチジン酸、大豆調製物等のラミニン５産生促進剤、グルコース、フルクトース、マンノース、ショ糖、トレハロース等の糖類、アルブチン、コウジ酸等の美白剤、ノニル酸ワレニルアミド、ニコチン酸ベンジルエステル、ニコチン酸β−ブトキシエチルエステル、カプサイシン、ジンゲロン、カンタリスチンキ、イクタモール、カフェイン、タンニン酸、α−ボルネオール、ニコチン酸トコフェロール、イノシトールヘキサニコチネート、シクランデレート、シンナリジン、トラゾリン、アセチルコリン、ベラパルミ、セファランチン、γ−オリザノール等の血行促進剤、硫黄、チアントール等の抗脂漏剤。 Specific examples of the ingredients that can be blended include metal sequestering agents such as disodium edetate, trisodium edetate, sodium citrate, sodium polyphosphate, sodium metaphosphate, gluconic acid, caffeine, tannin, verapamil, tranexamic acid and Derivatives thereof, various crude drugs, tocopherol acetate, glycyrrhizic acid and its derivatives or salts thereof, glycyrrhetinic acid derivatives, salicylic acid derivatives, lysophosphatidylcholine and lysophosphatidic acid, laminin 5 production promoters such as soybean preparations, glucose, Sugars such as fructose, mannose, sucrose, trehalose, whitening agents such as arbutin, kojic acid, nonyl acid valenyl amide, nicotinic acid benzyl ester, nicotinic acid β-butoxyethyl ester, capsaicin, gingerone, cantalis tincture, Ctamol, caffeine, tannic acid, α-borneol, tocopherol nicotinate, inositol hexanicotinate, cyclandrate, cinnarizine, tolazoline, acetylcholine, verapalmi, cephalanthin, γ-oryzanol and other blood circulation promoters, sulfur, thianthol and other antitumor agents Seborrheic agent.
あるいは、多様な目的から、ヒノキチオール、酸化亜鉛、アラントイン、アロエベラエキス、オウゴン根エキス、オタネニンジンエキス、カキタンニンエキス、カニナバラエキス、カミツレ花エキス、セイヨウオドリギソウエキス、センチフォリアバラエキス、チャ葉エキス、トウセンカエキス、ハマメリスエキス、フユボダイジュエキス、マグワエキス、ヤグルマギクエキス、ユズエキス、ローマカミツレエキス、ローヤルゼリーエキス、ウコン抽出物、ブナの芽抽出物、加水分解カゼイン、米抽出物加水分解液、米ぬか抽出物、トウニン抽出物、クララ抽出物、チオタウリン、ヒポタウリン、マジョラム抽出物、シリカ被覆酸化亜鉛、イチヤクソウ抽出物、キシリトール、アルギニン及びその塩酸塩、セリン、オウバク抽出成分、オウレン抽出成分、カッコン抽出成分、シコン抽出成分、シャクヤク抽出成分、センブリ抽出成分、バーチ抽出成分、セージ抽出成分、ビワ抽出成分、ニンジン抽出成分、アロエ抽出成分、ゼニアオイ抽出成分、アイリス抽出成分、ブドウ抽出成分、ヨクイニン抽出成分、ヘチマ抽出成分、ユリ抽出成分、サフラン抽出成分、センキュウ抽出成分、ショウキョウ抽出成分、オトギリソウ抽出成分、ローズマリー抽出成分、ニンニク抽出成分、トウガラシ抽出成分、トウガラシ抽出成分、ワレモコウ抽出成分、チンピ、トウキ等、レチノール、酢酸レチノール等のビタミンＡ類、リボフラビン、酪酸リボフラビン、フラビンアデニンヌクレオチド等のビタミンＢ2類、ピリドキシン塩酸塩、ピリドキシンジオクタノエート等のビタミンＢ6類、Ｌ−アスコルビン酸、Ｌ−アスコルビン酸時パルミチン酸エステル、Ｌ−アスコルビン酸−２−硫酸ナトリウム、Ｌ−アスコルビン酸リン酸エステル、ＤＬ−α−トコフェロール−Ｌ−アスコルビン酸リン酸ジエステルジカリウム等のビタミンＣ類、パントテン酸カルシウム、Ｄ−パントテニルアルコール、パントテニルエチルエーテル、アセチルパントテニルエチルエーテル等のパントテン酸類、エルゴカルシフェロール、コレカルシフェロール等のビタミンＤ類、ニコチン酸、ニコチン酸アミド、ニコチン酸ベンジル等のニコチン酸類、α−トコフェロール、酢酸トコフェロール、ニコチン酸ＤＬ−α−トコフェロール、コハク酸ＤＬ−α−トコフェロール等のビタミンＥ類、ビタミンＰ、ビオチン等のビタミン類なども適宜配合することができる。 Alternatively, for various purposes, hinokitiol, zinc oxide, allantoin, aloe vera extract, eel root extract, ginseng extract, persimmon tannin extract, cana rose extract, chamomile flower extract, licorice extract, centifolia rose extract, tea leaf extract, tomato Mosquito extract, Hamamelis extract, Fuyubodaiju extract, Magwa extract, Cornflower extract, Yuzu extract, Roman chamomile extract, Royal jelly extract, Turmeric extract, Beech bud extract, Hydrolyzed casein, Rice extract hydrolyzate, Rice bran extract, Tonin Extract, Clara extract, thiotaurine, hypotaurine, marjoram extract, silica-coated zinc oxide, Ichiyakuso extract, xylitol, arginine and its hydrochloride, serine, buckwheat extract component, ole Extraction component, Cuckoo extract component, Shikon extract component, Peonies extract component, Assembly extract component, Birch extract component, Sage extract component, Loquat extract component, Carrot extract component, Aloe extract component, Zenia mushroom extract component, Iris extract component, Grape extract component , Yokuinin extract component, loofah extract component, lily extract component, saffron extract component, gypsum extract component, ginger extract component, hypericum extract component, rosemary extract component, garlic extract component, capsicum extract component, capsicum extract component, cracker extract component , Vitamin A such as retinol and retinol acetate, vitamin B2 such as riboflavin, riboflavin butyrate and flavin adenine nucleotides, vitamin B6 such as pyridoxine hydrochloride and pyridoxine dioctanoate, L-asco Vitamin C such as ruvic acid, L-ascorbic acid palmitate, L-ascorbic acid-2-sodium sulfate, L-ascorbic acid phosphate, DL-α-tocopherol-L-ascorbic acid diester dipotassium, Pantothenic acids such as calcium pantothenate, D-pantothenyl alcohol, pantothenyl ethyl ether, acetyl pantothenyl ethyl ether, vitamin D such as ergocalciferol, cholecalciferol, nicotinic acid, nicotinamide, benzyl nicotinate, etc. Vitamin E such as nicotinic acid, α-tocopherol, tocopherol acetate, DL-α-tocopherol nicotinate, DL-α-tocopherol succinate, vitamins such as vitamin P and biotin, and the like can be appropriately blended.
本発明の効果に関して以下の実施例によりさらに詳細に説明する。
表１及び表２記載の配合比率に従ってサンプルを調整した。
調製した毛髪洗浄剤組成物は下記各種測定法により、性能評価した。
The effects of the present invention will be described in further detail with reference to the following examples.
Samples were prepared according to the mixing ratios described in Table 1 and Table 2.
The performance of the prepared hair cleaning composition was evaluated by the following various measuring methods.
（性能評価方法）
１．泡質の比較を以下の実験にて評価を行った。
実施例、比較例に記載されている処方を調整し、10倍希釈した液を１００ｍL調整する。
ナショナル製ミキサー（MX-X47）に投入し、30秒間撹拌後、内容液をすべて１０００ｍLのメスシリンダーに移す。
5分間放置後、離水した液を取り除き、泡の容量を測定する。さらに、残った泡の重量を測定し、泡比重を求めた。
(Performance evaluation method)
1. The comparison of foam quality was evaluated in the following experiment.
The formulations described in Examples and Comparative Examples are adjusted, and 100 mL of a 10-fold diluted solution is adjusted.
Put into a national mixer (MX-X47), stir for 30 seconds, and transfer all contents to a 1000 mL measuring cylinder.
After leaving for 5 minutes, remove the liquid that has been removed and measure the foam volume. Further, the weight of the remaining foam was measured to determine the foam specific gravity.
２．使用感の測定
・評価方法
日本人女性の毛髪をブリーチ処理し、ダメージ毛を作成した。この毛髪を５０ｇ（約１５―２０ｃｍ）束ねた毛束を使用した。
まず、毛束を十分濡らし、２ｃｃの評価溶液で洗浄し洗浄中の指通りを評価した。
さらにすすいでいる時の指通り、
乾燥後の指通りを評価した。
評価は専門パネラー１０名が官能評価し、以下の基準で判定し、平均値を算出した。
・評価基準
５：全く引っかからず指が通せる
４：僅かに引っ掛かりを感じるが容易に指が通せる
３：引っ掛かりを感じるが絡まずに指が通せる
２；指に引っかかり髪が絡みやすく、指通りが悪い
１：髪が引っかかり、指が通らない
2. Method of measuring and evaluating the feeling of use The hair of a Japanese woman was bleached to create damaged hair. A hair bundle in which 50 g (about 15-20 cm) of this hair was bundled was used.
First, the hair bundle was sufficiently wetted, washed with 2 cc of the evaluation solution, and the fingering during washing was evaluated.
Furthermore, as you finger when rinsing,
The fingering after drying was evaluated.
The evaluation was conducted by sensory evaluation by 10 professional panelists, determined according to the following criteria, and an average value was calculated.
・ Evaluation criteria 5: Fingers can be passed without being caught at all 4: Fingers can be easily passed through, but they can be easily passed through 3: Fingers can be passed through without being entangled 2; Bad street 1: Hair gets caught and fingers cannot pass
３．液の粘度の測定
各サンプルを２５℃恒温器に６時間静置した後、Ｂ型回転粘度計にて２５℃の粘度を測定した。
3. Measurement of Viscosity of Liquid Each sample was allowed to stand in a thermostat at 25 ° C. for 6 hours, and then the viscosity at 25 ° C. was measured with a B-type rotary viscometer.
※２ 花王社製；エマール２０C
※３ 川研ファインケミカル社製；ソフタゾリンCPB―R
※４ 花王社製；アンヒトール２０HD
※５ 三晶社製；JAGUAR C-17
※６ 日本ルブリゾール社製；ＳＥＮＳＯＭＥＲ ＣＴ−４００
※７ 川研ファインケミカル社製；アラノンALE
※８ 旭化成社製；アミノサーファクトACDS-L
※９ 旭化成社製；アミノフォーマーFLDS-L
※１０ 東邦化学社製；ネオスコープ CN-30
※１１ 川研ファインケミカル社製；ソイポンSLE
※１２ 川研ファインケミカル社製；アミゾールCME
※１３ 東レ・ダウコーニング社製；ＢＹ１１−０２６
※１４ 東レ・ダウコーニング社製；１５０３Ｆｌｕｉｄ
※１５ クローダジャパン社製；１８MEA
※１６ 横関油脂社製；精製椿油
※１７ 日光ケミカル社製；アルガンオイル
* 2 Made by Kao Corporation; EMAL 20C
* 3 Kawaken Fine Chemicals; Softazoline CPB-R
* 4 Made by Kao Corporation: Anhitor 20HD
* 5 Made by Sankisha; JAGUAR C-17
* 6 Nippon Lubrizol Corporation; SENSOMER CT-400
* 7 Made by Kawaken Fine Chemicals; Alanon ALE
* 8 Asahi Kasei Corporation; Amino Surfact ACDS-L
* 9 Asahi Kasei Corporation; Amino Former FLDS-L
* 10 Toho Chemical Co., Ltd .; Neoscope CN-30
* 11 Kawaken Fine Chemical Co., Ltd .; Soypon SLE
* 12 Kawaken Fine Chemical Co., Ltd .; Amizole CME
* 13 Toray Dow Corning; BY11-026
* 14 Toray Dow Corning; 1503 Fluid
* 15 Made by Croda Japan; 18MEA
* 16 Yokoseki Yushi Co., Ltd .; refined coconut oil * 17 Nikko Chemical Co., Ltd .; Argan Oil
表１の性能評価に関して、本発明毛髪洗浄剤組成物の範囲内で調製された実施例１〜１６は、目的とする「軽いふわふわの泡質」であることは泡比重が比較的小さい値でまとまっていることから実証でき、官能評価によるコメントにも「軽い泡質」という表現が使用されていた。また、洗髪、すすぎ、乾燥後を通して指通り使用感が高いスコアでまとまっている。また調整サンプルの粘度は２０００〜５０００ｍＰａ・ｓの範囲内にあり、ハンドリング性に優れる処方となっており本発明の解決課題をすべて満たしていることが分かる。 Regarding the performance evaluation in Table 1, Examples 1 to 16 prepared within the range of the hair cleansing composition of the present invention are intended to be the “light and fluffy foam quality” that the foam specific gravity is a relatively small value. It was proved from the fact that it was organized, and the expression “light foam” was also used in comments by sensory evaluation. In addition, it has a high score for use feeling after washing, rinsing and drying. Moreover, the viscosity of the adjusted sample is in the range of 2000 to 5000 mPa · s, and the formulation is excellent in handling properties, and it can be seen that all the problems to be solved by the present invention are satisfied.
一方、表２の比較例群と表１の評価を比べた際、
比較例１は実施例４に対してＮ−アシル−Ｎ−メチル−β−アラニン塩を配合しなかった場合であるが、この場合泡質及び粘度は満足いくものの使用感の評価が悪い。
比較例２は、本発明の範囲を超えてＮ−アシル−Ｎ−メチル−β−アラニン塩を配合した場合は、泡質、使用感には満足できるがこれらの、粘度が２０００ｍＰａ・ｓ未満となり、ハンドリング性に不満が残る結果となった。
比較例３〜６は、Ｎ−アシル−Ｎ−メチル−β−アラニン塩以外のＮ-アシルアミノ酸を配合し例であるが、泡質、使用感は充分に満足できるものであったが組成物の粘度が崩れており、粘度が２０００ｍＰａ・ｓ未満となり、ハンドリング性に不満が残る結果となった。これらのサンプルはノニオン界面活性剤の添加や水溶性増粘高分子を添加することによりハンドリング性は改善できるが、前述したとおりその場合「軽い泡質」を実感できなくなってしまう。
On the other hand, when comparing the comparative example group of Table 2 and the evaluation of Table 1,
Although the comparative example 1 is a case where N-acyl-N-methyl-β-alanine salt is not blended with respect to Example 4, the foam quality and the viscosity are satisfactory in this case, but the feeling of use is poor.
In Comparative Example 2, when the N-acyl-N-methyl-β-alanine salt was blended beyond the scope of the present invention, the foam quality and feeling of use were satisfactory, but the viscosity was less than 2000 mPa · s. As a result, dissatisfaction with the handling performance remained.
Comparative Examples 3 to 6 are examples in which N-acylamino acids other than N-acyl-N-methyl-β-alanine salts were blended, but the foam quality and feeling of use were sufficiently satisfactory, but the compositions The viscosity was less than 2000 mPa · s, resulting in dissatisfaction with handling properties. These samples can be improved in handling properties by adding a nonionic surfactant or a water-soluble thickening polymer, but as described above, in that case, it becomes impossible to realize “light foam quality”.
比較例７は、実施例１〜３記載の処方中のノニオン性界面活性剤が本発明の範囲を超えて配合された例である。粘度、使用感は満足いくものであったが、泡密度が急激に上昇し前述したとおりその場合「軽い泡質」を実感できなくなってしまった。 Comparative Example 7 is an example in which the nonionic surfactant in the formulations described in Examples 1 to 3 was blended beyond the scope of the present invention. Although the viscosity and the feeling of use were satisfactory, the foam density rapidly increased, and as described above, it was impossible to realize the “light foam quality”.
比較例８は実施例４から特定の両性又は双性界面活性剤が範囲外になった物であるが、泡質、使用感は満足できるが、粘度構築できていない。 Comparative Example 8 is a product in which the specific amphoteric or zwitterionic surfactant is out of the range from Example 4, but the foam quality and feeling of use are satisfactory, but the viscosity cannot be constructed.
比較例９は実施例４から中性無機塩が範囲外になった物であるが、泡質は満足できるが、使用感、粘度が満足できない。このことは本発明において中性無機塩が粘度構築のみならず、コアセルベーションの発生にも影響を与えていることを示唆する。 Although the comparative example 9 is a thing from which neutral inorganic salt became out of the range from Example 4, although foam quality is satisfactory, a feeling of use and a viscosity cannot be satisfied. This suggests that in the present invention, the neutral inorganic salt affects not only the viscosity build but also the occurrence of coacervation.
比較例１０は実施例４からカチオン化ガラクトマンナンが範囲外になった物であるが、コンディショニング成分を失っているので使用感が悪い。 In Comparative Example 10, the cationized galactomannan was out of the range from Example 4, but the feeling of use was poor because the conditioning component was lost.
以上の様に本発明は、きわめて限定された範囲内ではあるが、解決の課題としていた「軽いふわふわの泡質を維持し、望まれる粘度を維持した上に、洗髪からすすぎまでの滑らかさ、指通り性を向上させ、乾燥時においても髪の指通り性、まとまり感、柔らかさ、ハリコシ感等のコンディショニング効果を発現できる毛髪洗浄剤組成物」を充分に実現させていることが判明した。
As described above, although the present invention is within a very limited range, the problem to be solved was "maintaining a light fluffy foam quality, maintaining a desired viscosity, and smoothing from shampooing to rinsing, It has been found that a hair cleansing composition that can improve the finger-penetrating property and can exhibit the conditioning effects such as the finger-performing property, the feeling of unity, the softness, and the harshness even when dry.
本発明、毛髪洗浄剤組成物により、軽いふわふわの泡質を維持し、望まれる粘度を維持した上に、洗髪からすすぎまでの滑らかさ、指通り性を向上させ、乾燥時においても髪の指通り性、まとまり感、柔らかさ、ハリコシ感等のコンディショニング効果を付与することができる。
The hair cleansing composition of the present invention maintains a light and fluffy foam quality, maintains the desired viscosity, improves the smoothness from hair washing to rinsing, and improves the fingering property. Conditioning effects such as street, unity, softness, and firmness can be imparted.
Claims (3)
（Ｂ）一般式（１）で示される特定の両性又は双性界面活性剤 １．０〜５．０重量％
［但し式中 sは０又は１の整数であり、
Ｒ１はsが１の時、炭素数７〜２１の炭化水素鎖を示し、それらの混合物でも良く、
Ｒ１はsが０の時、炭素数８〜２２の炭化水素鎖を示し、それらの混合物でも良い。
Ｒ２は炭素数１〜３のアルキレン基であり、水酸基が結合されていても良い。
Ｑ−は−ＣＯＯ−基、乃至は−ＳＯ３ −基を示す。］
（Ｃ）カチオン化ガラクトマンナン ０．２〜１．０重量％
（Ｄ）Ｎ−アシル−Ｎ−メチル−β−アラニン塩 ０．２〜２．０重量％
（Ｅ）中性無機塩 ０．１〜３．０重量％
（Ｆ）脂肪酸ジエタノールアミドを実質的に含有しないノニオン性界面活性剤を１．０重量％以下
（Ｇ）精製水 残分（組成物全体を１００重量％とする量）を含有する毛髪洗浄剤組成物。 (A) Alkyl ether sulfate type anionic surfactant 8.0 to 20.0% by mass
(B) Specific amphoteric or zwitterionic surfactant represented by general formula (1) 1.0 to 5.0% by weight
[Wherein s is an integer of 0 or 1,
R 1 represents a hydrocarbon chain having 7 to 21 carbon atoms when s is 1, and may be a mixture thereof.
R 1 represents a hydrocarbon chain having 8 to 22 carbon atoms when s is 0, and may be a mixture thereof.
R 2 is an alkylene group having 1 to 3 carbon atoms, and a hydroxyl group may be bonded thereto.
Q - is -COO - group, or is -SO 3 - a group. ]
(C) Cationized galactomannan 0.2 to 1.0% by weight
(D) N-acyl-N-methyl-β-alanine salt 0.2 to 2.0% by weight
(E) Neutral inorganic salt 0.1 to 3.0% by weight
(F) A hair cleansing composition containing 1.0% by weight or less of a nonionic surfactant substantially free from fatty acid diethanolamide (G) a residue of purified water (amount that makes the entire composition 100% by weight) object.
The hair cleansing composition according to claim 1 or 2, comprising at least one sub-conditioning agent selected from various silicones, silicone derivatives and oil agents having a hair damage care care effect.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2015170798A JP2017048128A (en) | 2015-08-31 | 2015-08-31 | Hair washing agent composition |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2015170798A JP2017048128A (en) | 2015-08-31 | 2015-08-31 | Hair washing agent composition |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JP2017048128A true JP2017048128A (en) | 2017-03-09 |
Family
ID=58278429
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015170798A Pending JP2017048128A (en) | 2015-08-31 | 2015-08-31 | Hair washing agent composition |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP2017048128A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2018188390A (en) * | 2017-05-08 | 2018-11-29 | クラシエホームプロダクツ株式会社 | Thickening method for composition containing amino acid-based anionic surfactant, and thickening composition |
| CN112218614A (en) * | 2018-06-12 | 2021-01-12 | 花王株式会社 | Cleaning agent |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2004143072A (en) * | 2002-10-23 | 2004-05-20 | Kose Corp | Cleaner composition |
| JP2006131579A (en) * | 2004-11-09 | 2006-05-25 | Kanebo Ltd | Damaged hair improving agent and hair cosmetic blended with the same |
| JP2007332035A (en) * | 2006-06-12 | 2007-12-27 | Kracie Home Products Kk | Ameliorating agent for damaged hair and hair cosmetic comprising the same formulated therein |
-
2015
- 2015-08-31 JP JP2015170798A patent/JP2017048128A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2004143072A (en) * | 2002-10-23 | 2004-05-20 | Kose Corp | Cleaner composition |
| JP2006131579A (en) * | 2004-11-09 | 2006-05-25 | Kanebo Ltd | Damaged hair improving agent and hair cosmetic blended with the same |
| JP2007332035A (en) * | 2006-06-12 | 2007-12-27 | Kracie Home Products Kk | Ameliorating agent for damaged hair and hair cosmetic comprising the same formulated therein |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2018188390A (en) * | 2017-05-08 | 2018-11-29 | クラシエホームプロダクツ株式会社 | Thickening method for composition containing amino acid-based anionic surfactant, and thickening composition |
| CN112218614A (en) * | 2018-06-12 | 2021-01-12 | 花王株式会社 | Cleaning agent |
| CN112218614B (en) * | 2018-06-12 | 2023-08-01 | 花王株式会社 | Cleaning agent |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US10265261B2 (en) | Cleansing compositions with conditioning properties | |
| JP6235844B2 (en) | Cleaning composition for skin or hair | |
| JP4912483B2 (en) | Concentrated liquid detergent composition and method for producing the same | |
| US20190365623A1 (en) | Non-sulfate concentrated rinse-off cleansing composition | |
| EP3439624B1 (en) | Personal care compositions and methods for using such compositions | |
| JP2019156727A (en) | Cleanser composition | |
| JP2014125477A (en) | Foam-shaped hair cosmetic | |
| JP5616608B2 (en) | Hair cosmetics | |
| US20110124542A1 (en) | Composition Containing Surfactants and Having a Special Emulsifier Mixture | |
| EP2436371A1 (en) | Hair cosmetic | |
| JP7201411B2 (en) | Hair cleanser composition | |
| JP2013163658A (en) | Skin detergent composition | |
| JP5616609B2 (en) | Hair cosmetics | |
| JP2017048128A (en) | Hair washing agent composition | |
| JP2007015951A (en) | Hair cosmetic | |
| JP5616607B2 (en) | Hair cosmetics | |
| JP5562609B2 (en) | Hair cosmetics | |
| JP5409287B2 (en) | Hair cosmetics | |
| JP7143727B2 (en) | hair cosmetics | |
| EP3439625B1 (en) | Personal care compositions and methods for using such compositions | |
| JP2005154286A (en) | Hair cosmetic | |
| JP2002308759A (en) | Cleaning cosmetic composition containing anionic surfactant derived from amino acid and silicone and use of the composition | |
| JP2005306786A (en) | Hair cosmetic | |
| JP2005206482A (en) | Hair cosmetic | |
| JP2010159234A (en) | Hair detergent |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20180704 |
|
| RD02 | Notification of acceptance of power of attorney |
Free format text: JAPANESE INTERMEDIATE CODE: A7422 Effective date: 20180704 |
|
| RD03 | Notification of appointment of power of attorney |
Free format text: JAPANESE INTERMEDIATE CODE: A7423 Effective date: 20180704 |
|
| A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20190521 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20190528 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20190719 |
|
| A02 | Decision of refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A02 Effective date: 20191210 |