JP2017029965A - Alternating current electrolytic hydrogen water production method, and in-vivo radioactive material discharge method - Google Patents

Abstract

PROBLEM TO BE SOLVED: To solve the problem that, though a radioactive material, especially cesium 137, has a long half-life of 30 years, and exerts a serious influence on a human being by a food chain, an efficient decontamination method of internal cesium is not established yet.SOLUTION: Discharge of a radioactive material taken into an organism is promoted by oral administration of alternating current electrolytic hydrogen water.SELECTED DRAWING: Figure 1

Description

  The present invention relates to a method for producing AC electrolyzed hydrogen water and a method for promoting discharge by using AC electrolyzed hydrogen water obtained by activating a radioactive substance incorporated in a living body.

  Radioactive materials such as uranium are used as fuel in nuclear power plants, but once released from a nuclear reactor as in the Fukushima nuclear accident, they are taken into living organisms and have a great impact on them.

  Examples of radioactive substances released by accident include radioactive iodine, radioactive cesium, and radioactive strontium (Non-Patent Document 1).

  The removal of radioactive substances taken into the living organisms is said to be effective for the intake of alginic acid and phosphate for the discharge of strontium, and the intake of seaweeds for the discharge of radioactive iodine. Reference 2).

AC electrolyzed hydrogen water contains many H positive ions, H radicals, H negative ions and hydrogen molecules (H ₂ ), and captures ROS to protect DNA from oxidative damage by reactive oxygen species (ROS). (Non-Patent Documents 3 and 4). In particular, H ₂ has been reported to capture and suppress various ROSs of oxidative stress-related diseases (Non-patent Document 5).

The harmful effects of biological tissues are mediated through increased production of hydroxyl radicals (OH.). Hydrogen (H ₂ ) selectively reduces OH · and exhibits antioxidant activity (Non-patent Document 6). It has also been demonstrated that hydrogen (H ₂ ) can protect the gastrointestinal tract from gamma radiation in cultured human cells and mice (Non-patent Documents 7 and 8). However, the mechanism of action of H ₂ has not been fully elucidated.

  Nuclear accident, environmental pollution, Eiji Nakajima, University of Tokyo Press, 2014

  Radiation removal technology in human body, National Institute of Radiological Sciences, Kodansha, 2011

  Shirahata S, Kabayama S, Nakano M, Miura T, Kusumoto K, Gotoh M, Hayashi H, Otsubo K, Morisawa S, Katakura Y: Electrolyzed-reduced water scavenges active oxygen species and protects DNA from oxidative damage. Biophys Biochem Res Commun 1997, 234: 269-274.

  Ohsawa I, Ishikawa M, Takahashi K, Watanabe M, Nishimaki K, Yamagata K, Katsura K, Katayama Y, Asoh S, Ohta S: Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radials. Nature Med 2007, 13: 688-694.

  Qian L, Cao F, Cui J, Huang Y, Zhou X, Liu S, Cai J. et al. Radioprotective effect of hydrogen in cultured cells and mice. Free Radic Res 44: 275-282.

  Ohsawa I, Ishikawa M, Takahashi K et al: Hydrogen acts as a therapeutic antioxidant by selective reducing toxicogen oxygen. Nat Med, 2007; 13: 688-94.

  Ministry of Education (2010): Japan food standard component table

  Qian L, Cao F, Cui J: Radioprotective effect of hydrogen in cultured cells and mice. Free Radical Res, 2010; 44: 275-82

  Radioactive materials, especially cesium 137, have a long half-life of 30 years, and have a serious impact on humans through the food chain. However, an efficient decontamination method for cesium in vivo has not been established.

The present invention performs effective decontamination using AC electrolytic hydrogen water in order to discharge radioactive substances accumulated in living organisms, particularly radioactive cesium, to the outside of the body.

  The AC electrolyzed hydrogen water generator is characterized in that AC electrolyzed hydrogen water is generated by a single-phase, two-phase or three-phase AC current of 100 to 230 V, preferably by a three-phase AC power source of 200 volts or more. .

  As an AC electrolytic hydrogen water production method, the electrode may include two or more electrodes. In general, it can be any shape that can effectively conduct electricity through the aqueous feed solution between itself and other electrodes, including planar electrodes, rod electrodes, and porous electrodes. Although it can, it is not limited to these. The electrodes can be shaped and arranged to provide a substantially uniform gap between the electrodes. On the other hand, the electrodes can have different shapes and different dimensions, and can be arranged at unequal intervals.

  The electrodes are usually metallic conductive materials, but non-metallic conductive materials such as carbon can also be used. The electrode material may be the same or different. In order to minimize corrosion, chemical resistant metals are preferably used. Preferred electrode metals are titanium, iron, nickel, chromium, and alloys and oxides thereof, as well as stainless steel, platinum, palladium, iridium, and ruthenium.

  Several electrolytic cells can be arranged in series or in parallel.

  As a method for discharging radioactive materials in vivo, the discharge of radioactive materials taken into the living body is promoted by orally administering AC electrolytic hydrogen water.

  According to the present invention, it is possible to remove radioactive substances taken into the living body safely and without side effects, easily and inexpensively as drinking water in normal life.

Changes in dry weight of poultry organs after 1 week, 3 weeks and 5 weeks

Temporal change of cesium 137 contained in breast meat

Temporal change of cesium 137 contained in chicken meat

Temporal change of cesium 137 contained in thigh meat

    The AC electrolyzed hydrogen water produced by the AC electrolyzed hydrogen water production method was prepared by electrolysis using a stainless steel electrode with a 200V three-phase AC power source. The AC electrolyzed hydrogen water produced using this apparatus has pH (6.8), dissolved hydrogen (DH) (0.3 ppm), redox potential (ORP) (521 mV) and dissolved oxygen (DO) (2. 59 ppm).

  Radiocesium in the method for discharging radioactive materials in vivo was prepared for intraperitoneal injection into poultry for artificial internal exposure after dissolution in physiological saline and filtration sterilization.

    When the total weight of the poultry reached 2.5 kg, intraperitoneal injection of radioactive cesium-containing physiological saline was performed. Poultry was divided into two groups, the first group was supplied with AC electrolytic hydrogen water, and the second group was given tap water as drinking water.

  The physiological saline was radiation cesium 1.5 becquerel / ml, and 20 ml was injected into the abdominal cavity of poultry.

  Radioactive cesium 137 in physiological saline was measured using a gamma ray spectrometer (LB2054, BERTHOLD TECHNOLOGIES & Co. KG, Germany).

  Poultry was slaughtered during the first, third and fifth weeks. The organ was extracted by normal meat processing techniques. The organs were measured for the amount of radioactive cesium contained in breast, thigh and white meat (sasami).

  The extracted organs were freeze-dried, and the radioactivity contained in each organ was measured for 18 hours using the above-described gamma ray spectrometer. The measured value was expressed as the amount of radioactive cesium per dry weight.

  FIG. 1 shows temporal changes in the organ weights of the AC electrolysis hydrogen water administration group and the tap water administration group. At 1 week, 3 weeks, and 5 weeks, the organ weights of the alternating electrolysis hydrogen water administration group and the tap water administration group in each of the meat of the meat meat, breast meat, and white meat There was no significant difference.

Figures 2, 3 and 4 show the influence of AC electrolyzed hydrogen water on the radiocesium excretion of each organ. FIG. 2 is a temporal change in the amount of radioactive cesium in breast meat. The measured amount decreased at 1, 3 and 5 weeks, and a significant difference was observed between the AC electrolytic hydrogen water administration group and the tap water administration group at 3 and 5 weeks. Although FIG. 3 relates to the fillet and FIG. 4 relates to the thigh, the amount of radiation cesium is significantly decreased in the AC electrolyzed water administration group as compared with the breast water, compared to the tap water administration group.

    From the above, it is shown that the supply of AC electrolysis hydrogen water to poultry can efficiently discharge radioactive cesium in the body, and the use of AC electrolysis hydrogen water is effective for the discharge of radioactive cesium incorporated into living organisms. It was done.

Claims (4)

An AC electrolytic hydrogen water production method containing H plus ions, H radicals, H minus ions, H _2, metal particles, and metal ions by flowing an electric current between electrodes using an AC power source.   2. The method of claim 1, wherein the power supply is selected from a single phase, a two-phase, and a three-phase, and a voltage of 100 to 230 V is used.   The method for producing an aqueous solution of alternating current electrolytic hydrogen according to claim 1 or 2, wherein the metal particles and metal ions in the aqueous solution of alternating current electrolytic hydrogen are eluted from an electrode.   A method for discharging a radioactive substance in a living body, which promotes excretion of the radioactive substance by orally administering the alternating-current electrolytic hydrogen water to a living organism.