JP2016540773A5 - - Google Patents
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- JP2016540773A5 JP2016540773A5 JP2016536710A JP2016536710A JP2016540773A5 JP 2016540773 A5 JP2016540773 A5 JP 2016540773A5 JP 2016536710 A JP2016536710 A JP 2016536710A JP 2016536710 A JP2016536710 A JP 2016536710A JP 2016540773 A5 JP2016540773 A5 JP 2016540773A5
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- Prior art keywords
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- cancer
- compound
- pharmaceutically acceptable
- acceptable salt
- Prior art date
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| JP2016540773A JP2016540773A (ja) | 2016-12-28 |
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| GB201516504D0 (en) * | 2015-09-17 | 2015-11-04 | Astrazeneca Ab | Imadazo(4,5-c)quinolin-2-one Compounds and their use in treating cancer |
| WO2017059357A1 (en) | 2015-09-30 | 2017-04-06 | Vertex Pharmaceuticals Incorporated | Method for treating cancer using a combination of dna damaging agents and atr inhibitors |
| EP3461480A1 (en) | 2017-09-27 | 2019-04-03 | Onxeo | Combination of a dna damage response cell cycle checkpoint inhibitors and belinostat for treating cancer |
| JP2022502399A (ja) | 2018-09-26 | 2022-01-11 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングMerck Patent Gesellschaft mit beschraenkter Haftung | がんの治療のためのｐｄ−１アンタゴニスト、ａｔｒインヒビター、および白金製剤の組合せ |
| CA3116234A1 (en) | 2018-10-15 | 2020-04-23 | Merck Patent Gmbh | Combination therapy utilizing dna alkylating agents and atr inhibitors |
| CN114369096A (zh) | 2020-10-16 | 2022-04-19 | 上海迪诺医药科技有限公司 | 三杂环衍生物、其药物组合物及应用 |
| CN115466258A (zh) * | 2021-06-11 | 2022-12-13 | 成都苑东生物制药股份有限公司 | Atr抑制剂及其用途 |
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| WO2008016192A2 (en) * | 2006-08-04 | 2008-02-07 | Takeda Pharmaceutical Company Limited | Fused heterocyclic derivative and use thereof |
| UA110324C2 (en) * | 2009-07-02 | 2015-12-25 | Genentech Inc | Jak inhibitory compounds based on pyrazolo pyrimidine |
| US9018395B2 (en) * | 2011-01-27 | 2015-04-28 | Université de Montréal | Pyrazolopyridine and pyrazolopyrimidine derivatives as melanocortin-4 receptor modulators |
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