JP2016539185A5 - - Google Patents
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- Publication number
- JP2016539185A5 JP2016539185A5 JP2016554169A JP2016554169A JP2016539185A5 JP 2016539185 A5 JP2016539185 A5 JP 2016539185A5 JP 2016554169 A JP2016554169 A JP 2016554169A JP 2016554169 A JP2016554169 A JP 2016554169A JP 2016539185 A5 JP2016539185 A5 JP 2016539185A5
- Authority
- JP
- Japan
- Prior art keywords
- procedure
- synthesis process
- nitro
- benzyl
- absence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 claims 7
- 230000015572 biosynthetic process Effects 0.000 claims 3
- 238000003786 synthesis reaction Methods 0.000 claims 3
- 238000006243 chemical reaction Methods 0.000 claims 2
- GUDMTEGDXVJZEE-UHFFFAOYSA-N n-benzyl-2-hydroxyacetamide Chemical compound OCC(=O)NCC1=CC=CC=C1 GUDMTEGDXVJZEE-UHFFFAOYSA-N 0.000 claims 2
- YZEUHQHUFTYLPH-UHFFFAOYSA-N 2-nitroimidazole Chemical compound [O-][N+](=O)C1=NC=CN1 YZEUHQHUFTYLPH-UHFFFAOYSA-N 0.000 claims 1
- CULUWZNBISUWAS-UHFFFAOYSA-N Benznidazole Chemical compound [O-][N+](=O)C1=NC=CN1CC(=O)NCC1=CC=CC=C1 CULUWZNBISUWAS-UHFFFAOYSA-N 0.000 claims 1
- 239000003054 catalyst Substances 0.000 claims 1
- 239000000376 reactant Substances 0.000 claims 1
- 239000007790 solid phase Substances 0.000 claims 1
- 239000002904 solvent Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SV2013004584 | 2013-11-19 | ||
| SV2013004584A SV2013004584A (es) | 2013-11-19 | 2013-11-19 | Procedimiento de manufactura para obtención de de n-bencil-2-(2-nitro-1h-imidazol-1-il)acetamida |
| PCT/SV2014/000001 WO2015076760A1 (es) | 2013-11-19 | 2014-11-19 | Procedimiento de manufactura para obtención de n-bencil-2-(2-nitro-1h-imidazol-1-il)acetamida |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016539185A JP2016539185A (ja) | 2016-12-15 |
| JP2016539185A5 true JP2016539185A5 (https=) | 2018-04-26 |
| JP6425734B2 JP6425734B2 (ja) | 2018-11-21 |
Family
ID=53179913
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016554169A Active JP6425734B2 (ja) | 2013-11-19 | 2014-11-19 | Ｎ−ベンジル−２−（２−ニトロ−１ｈ−イミダゾール−１−イル）アセトアミドを得るための製造工程 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US9765036B2 (https=) |
| JP (1) | JP6425734B2 (https=) |
| BR (1) | BR112016011160B1 (https=) |
| SV (1) | SV2013004584A (https=) |
| WO (1) | WO2015076760A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017205622A1 (en) * | 2016-05-25 | 2017-11-30 | Savant Neglected Diseases, Llc | Method of making benznidazole |
| WO2019240671A1 (es) * | 2018-06-11 | 2019-12-19 | Ministerio De Educación, Ciencia Y Tecnología | Método de manufactura para la producción de benznidazol y su escalado industrial |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3505349A (en) * | 1966-04-18 | 1970-04-07 | Hoffmann La Roche | 2-nitro-imidazolyl-1-acetamides |
| CA2404680C (en) * | 2000-05-17 | 2010-11-16 | Erlinda Handal Vega | Synthesis procedure for biphenylimidazolyl-(1)-phenylmethane and related compounds |
-
2013
- 2013-11-19 SV SV2013004584A patent/SV2013004584A/es active IP Right Grant
-
2014
- 2014-11-19 BR BR112016011160-5A patent/BR112016011160B1/pt active IP Right Grant
- 2014-11-19 US US15/033,238 patent/US9765036B2/en active Active - Reinstated
- 2014-11-19 JP JP2016554169A patent/JP6425734B2/ja active Active
- 2014-11-19 WO PCT/SV2014/000001 patent/WO2015076760A1/es not_active Ceased
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