JP2016537141A - 患者インタフェース - Google Patents
患者インタフェース Download PDFInfo
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- JP2016537141A JP2016537141A JP2016533717A JP2016533717A JP2016537141A JP 2016537141 A JP2016537141 A JP 2016537141A JP 2016533717 A JP2016533717 A JP 2016533717A JP 2016533717 A JP2016533717 A JP 2016533717A JP 2016537141 A JP2016537141 A JP 2016537141A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/13—General characteristics of the apparatus with means for the detection of operative contact with patient, e.g. lip sensor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
- A61M2205/583—Means for facilitating use, e.g. by people with impaired vision by visual feedback
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
- A61M2205/583—Means for facilitating use, e.g. by people with impaired vision by visual feedback
- A61M2205/584—Means for facilitating use, e.g. by people with impaired vision by visual feedback having a color code
Abstract
Description
鼻の上にフィットし、鼻孔を通じて気体を伝達する鼻マスク、
口の上にフィットし、口を通じて気体を伝達する口マスク、
鼻と口との両方の上にフィットし、鼻及び口に気体を伝達するフルフェイスマスク、並びに、
本発明の範囲内にあるマスクとしてみなされ、鼻孔へ直接的に気体を伝達する小さな鼻挿入部からなる鼻枕、である。
a)信号の生成のためのシグナリングメカニズム
b)シグナリング分子自体
c)レセプタ
クォーラムセンシング経路を調整する化合物又は相似器官、又は、
調整たんぱく質を調整する化合物又は配位子、又は、
植物及び食料又は藻から抽出されるような天然物質、又は、
フラノン及びその構造的相似器官などのレセプタ部位を競合的に結合することによってクォーラムセンシングを防止する化合物、又は、
合成化合物、又は、
マクロライド系抗生物質などの広く認められている薬剤、又は、
レセプタ活動を調整可能な既知のシグナリング分子又は前駆体の外来アゴニスト又はアンタゴニスト。従って、クォーラムセンシング防止剤は、上述の基準のうちの1又は複数の採用により発見され得る。
例1
採用される親水性シリコーンのクッションは、Elastosil LR3004/40による形成から準備され得る。ここで、Elastosil(登録商標)LR3004/40は、
12gのアルファオレフィンスルホン酸ナトリウム(BIO-TERGE(登録商標) AS-90 BEADS、ステファンカンパニー、ノースフィールド、イリノイ州、米国)が、7gの(1:1)エタノール及び水と3乃至4回混合されたものである。その後、19gのElastosil LR 3004/40 A(ワッカーシリコーン、独国)が、追加され、2回混合された。次いで、水及びエタノールが、約0.5gの水/エタノール相が残るまで除去され、コンポーネントBと良好に混合され、塊がない状態となった。溶媒が所望の程度に除去されるまで、真空下、70℃乃至80℃の温度で数時間、溶媒が除去された。溶液は、蒸発中、静かに混合された。
26gのElastosil LR 3004/40 Bが、追加され、均質的な混合物が得られるまで、2回乃至3回混合された。比A:Bは、1:1.37であり、比(A+soap):Bは、1.19:1である。混合物が、130℃乃至140℃の温度で20分間、モールドにおいて処理された。必要に応じて、真空下、約130℃の温度、及び、1時間のポスト硬化処理が採用され得る。
0.2gのアルラレッドACが、7gの(1:1)エタノール及び水に溶解され、次いで、12gのアルファオレフィンスルホン酸ナトリウム(BIO-TERGE AS-90 BEADS、ステファンカンパニー、ノースフィールド、イリノイ州、米国)と3回乃至4回混合された。その後、19gのElastosil LR 3004/40 A(ワッカーシリコーン、独国)が、追加され、2回混合された。次いで、水及びエタノールが、約0.5gの水/エタノール相が残るまで除去された。この手続きは、コンポーネントBとの良好な混合、及び、塊がない状態につながった。溶媒が所望の程度に除去されるまで、真空下、70℃乃至80℃の温度で数時間、溶媒が除去された。溶液は、蒸発中、静かに混合された。
26gのElastosil LR 3004/40 Bが、追加され、均質的な混合物が得られるまで、2回乃至3回混合された。比A:Bは、1:1.37であり、比(A+soap):Bは、1.19:1である。混合物が、130℃乃至140℃の温度で20分間、モールドにおいて処理された。必要に応じて、真空下、約130℃の温度、及び、1時間のポスト硬化処理が採用され得る。
この例では、工業用のシリコーン弾性体Elastosil LR 3003/5(独国のワッカーシリコーン社から広く入手可能)が、シリコーン前駆体物質として使用された。シリコーン前駆体物質は、通常、2つのコンポーネントA及びBを1:1の重量比で混合された2つのコンポーネントシステムである。コンポーネントAは、シリコーンプレポリマー活性ビニルグループと、白金触媒と、からなる。コンポーネントBは、シリコーンプレポリマー活性ビニルグループと、プレポリマーベアリングSi−Hグループと、からなる。ステファンカンパニー(ノースフィールド、イリノイ州、米国)から入手した、工業用のアルファオレフィンスルホン酸ナトリウムRCH=CH(CH2)nSO3Na(n=12−14)が使用された。12gのこの微細粉末(粒子サイズは、400μm未満)が、7gのエタノール及び水の混合物(50/50の重量%)と混合された。次いで、19gのシリコーン前駆体物質のコンポーネントAが、追加されるとともに、高速混合機で混合された。混合後、エタノール及び水が、少量(約0.5グラム)の水が残るまで、真空下、及び、60℃で除去された。次いで、シリコーン前駆体コンポーネントB(24.7g)が、追加され、得られた組成物が混合された。シリコーン前駆体A+Bに追加された工業用のアルファオレフィンスルホン酸ナトリウムは、従って、シリコーン前駆体(A+B)重量((アルファオレフィンスルホン酸ナトリウムの重量/シリコーンA+Bの重量)*100)の27.5重量%である。コンポーネントBに対するコンポーネントAの当該系の混合比は、1乃至1.3であった。材料サンプルが、130℃、10分乃至15分、及び、711psi(約49バール)のプレス成形により準備された。必要に応じて、真空下、約130℃の温度、及び、1時間のポスト硬化処理が採用され得る。
この例は、7gの水及びエタノール混合物(50/50の重量%)に対して、0.2gのアルラレッドACが追加され、そこに溶解された点を除いて、上記の例3に対応している。
Claims (17)
- 患者インタフェースのための部材であって、前記部材は、
所定の機能を持つ少なくとも1つの機能材料と、
少なくとも1つのインジケータと、
を有し、
前記部材における前記少なくとも1つのインジケータの濃度は、前記少なくとも1つの機能材料の前記所定の機能と関連があり、前記少なくとも1つの機能材料及び前記少なくとも1つのインジケータは、皮膚接触材料において配置されている、患者インタフェースのための部材。 - 前記少なくとも1つの機能材料が、吸湿手段及び/又は抗菌剤を有する、請求項1記載の患者インタフェースのための部材。
- 前記吸湿手段が、親水性材料である、請求項2記載の患者インタフェースのための部材。
- 前記親水性材料が、シリコーンゴムを含むアルファオレフィンスルホン酸塩である、請求項3記載の患者インタフェースのための部材。
- 前記抗菌剤が、クォーラムセンシング防止剤である、請求項2記載の患者インタフェースのための部材。
- 前記少なくとも1つのインジケータが、着色剤である、請求項1記載の患者インタフェースのための部材。
- 前記着色剤が、天然食用色素又は人工食用色素である、請求項6記載の患者インタフェースのための部材。
- 前記食用色素が、アルラレッドAC、エリオグラウシン二ナトリウム塩、タートラジン、及び、ファストグリーンFCF、あるいは、それらの組み合わせからなるグループから選択される、請求項7記載の患者インタフェースのための部材。
- 前記部材が、異なる領域で共有され、前記領域の各々が、異なるインジケータを有する、請求項1記載の患者インタフェースのための部材。
- 前記領域の各々が、1つの機能材料の存在を示す、請求項9記載の患者インタフェースのための部材。
- 前記少なくとも1つのインジケータが、前記部材上に、グラフィカルパターン及び/又は少なくとも1つの文字を形成する、請求項1記載の患者インタフェースのための部材。
- 2以上のインジケータが存在し、前記2以上のインジケータが、前記2以上のインジケータの各々の第1の色とは異なる第2の色を形成する、請求項1記載の患者インタフェースのための部材。
- 前記第2の色が、補色である、請求項12記載の患者インタフェースのための部材。
- 前記少なくとも1つの機能材料及び前記少なくとも1つのインジケータが、前記部材において、均一に分布されている、請求項1記載の患者インタフェースのための部材。
- 前記部材が、機械的解放機構を通じて第2の部材と接続された第1の部材であり、これにより、ユーザに気体を輸送するための患者インタフェースを形成する、請求項1記載の患者インタフェースのための部材。
- 前記皮膚接触材料が、前記ユーザの顔に接触するためのクッション、額サポート、又は、マスクシェルの一部である、請求項1記載の患者インタフェースのための部材。
- 請求項1記載の部材を有する、ユーザに気体を輸送するための患者インタフェース。
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PCT/EP2014/077665 WO2015091304A1 (en) | 2013-12-20 | 2014-12-15 | Patient interface |
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EP (1) | EP3082924B1 (ja) |
JP (1) | JP2016537141A (ja) |
CN (1) | CN106061534B (ja) |
BR (1) | BR112016013881A2 (ja) |
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- 2014-12-15 JP JP2016533717A patent/JP2016537141A/ja active Pending
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WO2015091304A1 (en) | 2015-06-25 |
BR112016013881A2 (pt) | 2017-08-08 |
CN106061534B (zh) | 2019-06-07 |
EP3082924A1 (en) | 2016-10-26 |
US20160317771A1 (en) | 2016-11-03 |
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