JP2016536391A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2016536391A5 JP2016536391A5 JP2016524502A JP2016524502A JP2016536391A5 JP 2016536391 A5 JP2016536391 A5 JP 2016536391A5 JP 2016524502 A JP2016524502 A JP 2016524502A JP 2016524502 A JP2016524502 A JP 2016524502A JP 2016536391 A5 JP2016536391 A5 JP 2016536391A5
- Authority
- JP
- Japan
- Prior art keywords
- polymeric material
- medical implant
- polymer material
- consolidated
- consolidation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 238000000034 method Methods 0.000 claims 8
- 239000000463 material Substances 0.000 claims 4
- 239000007943 implant Substances 0.000 claims 3
- 239000002861 polymer material Substances 0.000 claims 3
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims 2
- 239000003963 antioxidant agent Substances 0.000 claims 2
- 230000003078 antioxidant effect Effects 0.000 claims 2
- 235000006708 antioxidants Nutrition 0.000 claims 2
- 238000007596 consolidation process Methods 0.000 claims 2
- 239000003431 cross linking reagent Substances 0.000 claims 2
- 238000010438 heat treatment Methods 0.000 claims 2
- 238000002844 melting Methods 0.000 claims 2
- 230000008018 melting Effects 0.000 claims 2
- ODBCKCWTWALFKM-UHFFFAOYSA-N 2,5-bis(tert-butylperoxy)-2,5-dimethylhex-3-yne Chemical compound CC(C)(C)OOC(C)(C)C#CC(C)(C)OOC(C)(C)C ODBCKCWTWALFKM-UHFFFAOYSA-N 0.000 claims 1
- XMNIXWIUMCBBBL-UHFFFAOYSA-N 2-(2-phenylpropan-2-ylperoxy)propan-2-ylbenzene Chemical compound C=1C=CC=CC=1C(C)(C)OOC(C)(C)C1=CC=CC=C1 XMNIXWIUMCBBBL-UHFFFAOYSA-N 0.000 claims 1
- NWYAYUUUUMPAEF-UHFFFAOYSA-N C.C=C(C(C(=O)O)O)C1=CC(=CC(=C1)C(C)(C)C)C(C)(C)C.C=C(C(C(=O)O)O)C1=CC(=CC(=C1)C(C)(C)C)C(C)(C)C.C=C(C(C(=O)O)O)C1=CC(=CC(=C1)C(C)(C)C)C(C)(C)C.C=C(C(C(=O)O)O)C1=CC(=CC(=C1)C(C)(C)C)C(C)(C)C Chemical compound C.C=C(C(C(=O)O)O)C1=CC(=CC(=C1)C(C)(C)C)C(C)(C)C.C=C(C(C(=O)O)O)C1=CC(=CC(=C1)C(C)(C)C)C(C)(C)C.C=C(C(C(=O)O)O)C1=CC(=CC(=C1)C(C)(C)C)C(C)(C)C.C=C(C(C(=O)O)O)C1=CC(=CC(=C1)C(C)(C)C)C(C)(C)C NWYAYUUUUMPAEF-UHFFFAOYSA-N 0.000 claims 1
- 229930003427 Vitamin E Natural products 0.000 claims 1
- 238000001816 cooling Methods 0.000 claims 1
- 229920006037 cross link polymer Polymers 0.000 claims 1
- 238000001125 extrusion Methods 0.000 claims 1
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 238000002156 mixing Methods 0.000 claims 1
- 150000002978 peroxides Chemical group 0.000 claims 1
- 235000019165 vitamin E Nutrition 0.000 claims 1
- 229940046009 vitamin E Drugs 0.000 claims 1
- 239000011709 vitamin E Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361892249P | 2013-10-17 | 2013-10-17 | |
| US61/892,249 | 2013-10-17 | ||
| PCT/US2014/060865 WO2015057943A2 (en) | 2013-10-17 | 2014-10-16 | Peroxide cross-linking and high temperature melting |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016536391A JP2016536391A (ja) | 2016-11-24 |
| JP2016536391A5 true JP2016536391A5 (enExample) | 2017-11-24 |
Family
ID=52828852
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016524502A Withdrawn JP2016536391A (ja) | 2013-10-17 | 2014-10-16 | 過酸化物架橋および高温溶融 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US10220547B2 (enExample) |
| EP (1) | EP3058017A4 (enExample) |
| JP (1) | JP2016536391A (enExample) |
| AU (1) | AU2014337296B2 (enExample) |
| CA (1) | CA2927056A1 (enExample) |
| WO (1) | WO2015057943A2 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010096771A2 (en) * | 2009-02-20 | 2010-08-26 | The General Hospital Corporation Dba | High temperature melting |
| US10220547B2 (en) | 2013-10-17 | 2019-03-05 | The General Hospital Corporation | Peroxide cross-linking and high temperature melting |
| US20150368375A1 (en) * | 2014-06-24 | 2015-12-24 | Biomet Manufacturing, Llc | Methods For Making Crosslinked Ultra High Molecular Weight Polyethylene |
| WO2017083476A1 (en) | 2015-11-12 | 2017-05-18 | The General Hospital Corporation | Methods of making therapeutic polymeric material |
| EP3411422A1 (en) | 2016-02-05 | 2018-12-12 | The General Hospital Corporation | Drug eluting polymer composed of biodegradable polymers applied to surface of medical device |
| KR102502942B1 (ko) * | 2016-06-10 | 2023-02-22 | 이-빔 서비시스, 인크. | 프로필렌 폴리머 또는 이것의 코폴리머의 용융 강도를 증가시키는 방법 |
| DE102016116597A1 (de) * | 2016-09-06 | 2018-03-08 | Aesculap Ag | Verfahren zur Herstellung eines vernetzten Formkörpers aus UHMWPE |
| WO2019046243A2 (en) | 2017-08-29 | 2019-03-07 | The General Hospital Corporation | UV-INITIATED REACTIONS IN POLYMERIC MATERIALS |
| WO2020102186A1 (en) * | 2018-11-13 | 2020-05-22 | The General Hospital Corporation | Methods for consolidating antibiotic-eluting polymeric materials |
| CN111135343B (zh) * | 2019-12-19 | 2021-09-14 | 江苏集萃先进高分子材料研究所有限公司 | 一种高交联高抗氧剂掺杂的人工关节假体材料及其制备方法 |
| US11952439B2 (en) | 2020-06-25 | 2024-04-09 | b-ONE Medical (Suzhou) Co., Ltd. | Surface gradient cross-linking method of ultra-high molecular weight polyethylene and the application thereof |
| US11970600B2 (en) | 2021-03-31 | 2024-04-30 | The General Hospital Corporation | Di-cumyl peroxide crosslinking of UHMWPE |
Family Cites Families (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3974132A (en) | 1975-05-15 | 1976-08-10 | Borg-Warner Corporation | Process for curing olefin polymers |
| GB2207436B (en) | 1987-07-24 | 1991-07-24 | Nat Research And Dev Corp The | Solid phase deformation process |
| US5032450A (en) * | 1990-01-31 | 1991-07-16 | Ppg Industries, Inc. | Microporous material having a coating of hydrophobic polymer |
| PL189246B1 (pl) | 1996-02-13 | 2005-07-29 | Gen Hospital Corp | Sposób otrzymywania usieciowanego polietylenu o ultrawysokim ciężarze cząsteczkowym, medyczna proteza do stosowania wewnątrz ciała oraz zastosowanie poddanego działaniu promieniowania polietylenu o ultrawysokim ciężarze cząsteczkowym |
| US5879400A (en) | 1996-02-13 | 1999-03-09 | Massachusetts Institute Of Technology | Melt-irradiated ultra high molecular weight polyethylene prosthetic devices |
| US8865788B2 (en) | 1996-02-13 | 2014-10-21 | The General Hospital Corporation | Radiation and melt treated ultra high molecular weight polyethylene prosthetic devices |
| US5827904A (en) | 1996-09-27 | 1998-10-27 | Hahn; David | Medical implant composition |
| US6017975A (en) | 1996-10-02 | 2000-01-25 | Saum; Kenneth Ashley | Process for medical implant of cross-linked ultrahigh molecular weight polyethylene having improved balance of wear properties and oxidation resistance |
| WO1998016258A1 (en) * | 1996-10-15 | 1998-04-23 | The Orthopaedic Hospital | Wear resistant surface-gradient cross-linked polyethylene |
| US6287685B1 (en) | 1997-12-09 | 2001-09-11 | 3M Innovative Properties Company | Rubber article capable of bonding to a pressure-sensitive adhesive and method of making |
| US6709742B2 (en) | 1998-05-18 | 2004-03-23 | Dow Global Technologies Inc. | Crosslinked elastic fibers |
| SE9900519D0 (sv) * | 1999-02-17 | 1999-02-17 | Lars Lidgren | A method for the preparation of UHMWPE doped with an antioxidant and an implant made thereof |
| ES2317905T3 (es) | 2000-04-27 | 2009-05-01 | Orthopaedic Hospital | Polietilenos resistentes a la oxidacion y resistentes al desgaste para protesis articulares humanas y procedimientos para prepararlos. |
| WO2002048259A2 (en) | 2000-12-12 | 2002-06-20 | Massachusetts General Hospital | Selective, controlled manipulation of polymers |
| US7205339B2 (en) | 2000-12-12 | 2007-04-17 | Massachusetts General Hospital | Selective controlled manipulation of polymers |
| WO2003059200A1 (en) | 2002-01-04 | 2003-07-24 | Massachusetts General Hospital | A high modulus crosslinked polyethylene with reduced residual free radical concentration prepared below the melt |
| US7819925B2 (en) * | 2002-01-28 | 2010-10-26 | Depuy Products, Inc. | Composite prosthetic bearing having a crosslinked articulating surface and method for making the same |
| EP1596755B1 (en) | 2003-01-16 | 2016-10-12 | Massachusetts General Hospital | Methods for making oxidation resistant polymeric material |
| US9445901B2 (en) | 2003-03-12 | 2016-09-20 | Deger C. Tunc | Prosthesis with sustained release analgesic |
| US20050090571A1 (en) * | 2003-10-27 | 2005-04-28 | Mehta Aspy K. | Expanded bead foams from propylene-diene copolymers and their use |
| AU2005209868B8 (en) | 2004-02-03 | 2010-06-03 | The General Hospital Corporation Dba Massachusetts General Hospital | Highly crystalline cross-linked oxidation-resistant polyethylene |
| AU2005244062B8 (en) | 2004-05-11 | 2010-08-05 | Cambridge Polymer Group, Inc. | Methods for making oxidation resistant polymeric material |
| US20070281004A1 (en) | 2004-08-25 | 2007-12-06 | He Vicky Y | Polymeric Film |
| US20060064653A1 (en) | 2004-09-21 | 2006-03-23 | Shuo Zhang | Automatic layout yield improvement tool for replacing vias with redundant vias through novel geotopological layout in post-layout optimization |
| CA2619502C (en) | 2005-08-18 | 2012-11-20 | Zimmer Gmbh | Ultra high molecular weight polyethylene articles and methods of forming ultra high molecular weight polyethylene articles |
| EP2441780A1 (en) | 2005-08-22 | 2012-04-18 | The General Hospital Corporation d/b/a Massachusetts General Hospital | Highly Crystalline Polyethylene |
| ATE529464T1 (de) | 2005-08-22 | 2011-11-15 | Gen Hospital Corp Dba Massachusetts General Hospital | Oxidationsbeständiges homogenisiertes polymermaterial |
| US20070077268A1 (en) | 2005-09-30 | 2007-04-05 | Depuy Products, Inc. | Hydrophobic carrier modified implants for beneficial agent delivery |
| US20070213835A1 (en) | 2005-11-04 | 2007-09-13 | Markus Wimmer | Plastic implant impregnated with an antibiotic |
| EP2110002B1 (en) * | 2007-01-25 | 2012-04-25 | The General Hospital Corporation | Methods for making oxidation-resistant cross-linked polymeric materials |
| CA2679274C (en) | 2007-03-02 | 2018-02-20 | The General Hospital Corporation | Cross-linking of antioxidant-containing polymers |
| ES2662102T3 (es) | 2007-04-10 | 2018-04-05 | Zimmer, Inc. | Un polietileno reticulado de peso molecular ultra alto estabilizado con antioxidantes para aplicaciones en dispositivos médicos |
| US8641959B2 (en) | 2007-07-27 | 2014-02-04 | Biomet Manufacturing, Llc | Antioxidant doping of crosslinked polymers to form non-eluting bearing components |
| WO2009045658A1 (en) | 2007-10-05 | 2009-04-09 | The Brigham And Women's Hospital, Inc. | Crosslinked polymers and methods of making the same |
| BRPI0820509A2 (pt) * | 2007-11-06 | 2015-06-16 | Dsm Ip Assests Bv | Processo para produzir polietileno de (ultra) alto peso molecular |
| US20090181253A1 (en) * | 2008-01-15 | 2009-07-16 | Nova Chemicals Inc. | Particulate interpenetrating network polymer |
| US20090243159A1 (en) * | 2008-03-26 | 2009-10-01 | Dehchuan Sun | Method for thermal crosslinking of previously irradiated polymeric material and medical implant |
| JP5676489B2 (ja) | 2009-02-19 | 2015-02-25 | スミス・アンド・ネフュー・オルソペディクス・アーゲー | 良好な身体応答を示す磨耗粒子を生じる医療用インプラント |
| WO2010096771A2 (en) | 2009-02-20 | 2010-08-26 | The General Hospital Corporation Dba | High temperature melting |
| EP2427225B8 (en) * | 2009-05-04 | 2017-03-22 | Smith & Nephew, Inc | Synergistic effects of blending multiple additives in uhmwpe |
| US8022115B2 (en) * | 2009-09-22 | 2011-09-20 | Quadrant Epp Ag | Anti-fouling ultrahigh molecular weight polyethylene compositions and methods of using the same |
| US9132209B2 (en) | 2010-05-07 | 2015-09-15 | Howmedia Osteonics Corp. | Surface crosslinked polyethylene |
| US8858979B1 (en) | 2011-01-28 | 2014-10-14 | Clemson University | Service induced byproducts for localized drug delivery in orthopaedic implants |
| WO2012119981A1 (en) * | 2011-03-04 | 2012-09-13 | Dsm Ip Assets B.V. | Geodesic radome |
| US20120267819A1 (en) | 2011-04-22 | 2012-10-25 | Biomet Manufacturing Corp. | Antioxidant doping of crosslinked polymers at high pressures |
| AU2013243693B2 (en) | 2012-04-04 | 2016-10-20 | The General Hospital Corporation | Peroxide cross-linking of polymeric materials in the presence of antioxidants |
| US10000305B2 (en) | 2012-05-11 | 2018-06-19 | The General Hospital Corporation | Antioxidant-stabilized joint implants |
| US9889224B2 (en) | 2012-08-06 | 2018-02-13 | The General Hospital Corporation | Spatial control of additives by high temperature |
| ITBO20130262A1 (it) | 2013-05-24 | 2014-11-25 | Gd Spa | Dispositivo alimentatore di prodotti di ridotte dimensioni longitudinali di macchine del settore del tabacco. |
| US10220547B2 (en) | 2013-10-17 | 2019-03-05 | The General Hospital Corporation | Peroxide cross-linking and high temperature melting |
| WO2017192347A1 (en) | 2016-05-02 | 2017-11-09 | The General Hospital Corporation | Implant surfaces for pain control |
| WO2019046243A2 (en) | 2017-08-29 | 2019-03-07 | The General Hospital Corporation | UV-INITIATED REACTIONS IN POLYMERIC MATERIALS |
-
2014
- 2014-10-16 US US15/030,206 patent/US10220547B2/en active Active
- 2014-10-16 WO PCT/US2014/060865 patent/WO2015057943A2/en not_active Ceased
- 2014-10-16 EP EP14853883.8A patent/EP3058017A4/en not_active Withdrawn
- 2014-10-16 JP JP2016524502A patent/JP2016536391A/ja not_active Withdrawn
- 2014-10-16 AU AU2014337296A patent/AU2014337296B2/en active Active
- 2014-10-16 CA CA2927056A patent/CA2927056A1/en not_active Abandoned
-
2019
- 2019-03-04 US US16/291,283 patent/US10981302B2/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR112018068992A2 (pt) | método para formar uma cera | |
| WO2015102886A3 (en) | Method to produce functionalized, low viscosity ethylene-based polymers | |
| MX379356B (es) | Material compactado tratado en superficie. | |
| WO2014052409A3 (en) | Gel comprising a phase-change material, method of preparing the gel, and thermal exchange implement comprising the gel | |
| SG11201706426YA (en) | Modified conjugated diene-based polymer and method for producing the same, and modified conjugated diene-based polymer composition | |
| EP3006049A4 (en) | Composition for heat melt extrusion and method for producing heat melt extruded product using same | |
| WO2012020336A3 (en) | Toughened polylactic acid fibers | |
| JP2010518197A5 (enExample) | ||
| EA024841B9 (ru) | Композиционный материал из отходов и вулканизованного каучука и способ его получения | |
| ES2720960T3 (es) | Composición de polímero procesada por fusión derivada de vainas foliares de árboles del género Arecaceae | |
| WO2017119779A8 (ko) | 고분자-그래핀 복합체 및 그 제조방법, 그리고 이를 이용한 고분자-그래핀 복합체 조성물 | |
| EP2952318A4 (en) | SHAPED SHAPE, MANUFACTURING METHOD AND APPLICATION THEREOF | |
| CA2899324C (en) | Anti-extrusion compositions for sealing and wear components | |
| BR112016002180A2 (pt) | composição amaciante de tecido, método para tratamento de tecido e uso de uma composição | |
| EP3162825A4 (en) | A-b block co-polymer, a-b block co-polymer production method, resin treatment pigment composition, resin treatment pigment composition production method, pigment dispersion, and pigment dispersion solution | |
| NZ735444A (en) | Method of and system for producing solid carbon materials | |
| EP3199574A4 (en) | Method for producing vulcanized rubber composition, vulcanized rubber composition, and studless tire using same | |
| EP3385327A4 (en) | Thermoplastic resin composition having excellent weather resistance, method for preparing same, and molded product comprising same | |
| EP3050921A4 (en) | Heat-resistant silane cross-linked resin molded article and production method for same, heat-resistant silane cross-linking resin composition and production method for same, silane masterbatch, and heat-resistant product employing heat-resistant silane cross-linked resin molded article | |
| MX2020000807A (es) | Proceso para preparar una composicion de entrega de farmaco. | |
| EP3165541A4 (en) | Graft polymer, resin colored matter, method for producing same, and resin composition containing resin colored matter | |
| FR2981600B1 (fr) | Procede de preparation de granules de polyamide | |
| MY199314A (en) | Encapsulated stabilizer compositions | |
| WO2015057943A3 (en) | Peroxide cross-linking and high temperature melting | |
| MX2018003747A (es) | Composiciones de poliolefina con propiedades mecanicas y de barrera mejoradas. |