JP2016536043A5 - - Google Patents

Info

Publication number

JP2016536043A5

JP2016536043A5 JP2016520581A JP2016520581A JP2016536043A5 JP 2016536043 A5 JP2016536043 A5 JP 2016536043A5 JP 2016520581 A JP2016520581 A JP 2016520581A JP 2016520581 A JP2016520581 A JP 2016520581A JP 2016536043 A5 JP2016536043 A5 JP 2016536043A5

Authority

JP

Japan

Prior art keywords

inhaler

dry powder

port

dose

inhaler according

Prior art date

2014-10-06

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Links

• Espacenet
• Global Dossier
• Discuss

• GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 claims 9
• 239000003814 drug Substances 0.000 claims 9
• 239000008101 lactose Substances 0.000 claims 9
• 239000000843 powder Substances 0.000 claims 9
• GIIZNNXWQWCKIB-UHFFFAOYSA-N Serevent Chemical compound C1=C(O)C(CO)=CC(C(O)CNCCCCCCOCCCCC=2C=CC=CC=2)=C1 GIIZNNXWQWCKIB-UHFFFAOYSA-N 0.000 claims 7
• 239000012530 fluid Substances 0.000 claims 4
• 229960004017 salmeterol Drugs 0.000 claims 4
• 229940079593 drug Drugs 0.000 claims 3
• 229940112141 dry powder inhaler Drugs 0.000 claims 3
• 229960000289 fluticasone propionate Drugs 0.000 claims 3
• WMWTYOKRWGGJOA-CENSZEJFSA-N fluticasone propionate Chemical compound C1([C@@H](F)C2)=CC(=O)C=C[C@]1(C)[C@]1(F)[C@@H]2[C@@H]2C[C@@H](C)[C@@](C(=O)SCF)(OC(=O)CC)[C@@]2(C)C[C@@H]1O WMWTYOKRWGGJOA-CENSZEJFSA-N 0.000 claims 3
• 239000002245 particle Substances 0.000 claims 3
• 229960005018 salmeterol xinafoate Drugs 0.000 claims 3
• YYAZJTUGSQOFHG-IAVNQIGZSA-N [(6s,8s,10s,11s,13s,14s,16r,17r)-6,9-difluoro-17-(fluoromethylsulfanylcarbonyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate;2-(hydroxymethyl)-4-[1-hydroxy-2-[6-(4-phenylbutoxy)hexylamino]eth Chemical compound C1=C(O)C(CO)=CC(C(O)CNCCCCCCOCCCCC=2C=CC=CC=2)=C1.C1([C@@H](F)C2)=CC(=O)C=C[C@]1(C)C1(F)[C@@H]2[C@@H]2C[C@@H](C)[C@@](C(=O)SCF)(OC(=O)CC)[C@@]2(C)C[C@@H]1O YYAZJTUGSQOFHG-IAVNQIGZSA-N 0.000 claims 2
• 208000006673 asthma Diseases 0.000 claims 2
• 239000006185 dispersion Substances 0.000 claims 2
• 229940114006 fluticasone / salmeterol Drugs 0.000 claims 2
• 208000006545 Chronic Obstructive Pulmonary Disease Diseases 0.000 claims 1
• 206010039085 Rhinitis allergic Diseases 0.000 claims 1
• 201000010105 allergic rhinitis Diseases 0.000 claims 1
• 230000029058 respiratory gaseous exchange Effects 0.000 claims 1
• 238000007789 sealing Methods 0.000 claims 1