JP2016534342A5 - - Google Patents
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- Publication number
- JP2016534342A5 JP2016534342A5 JP2016533754A JP2016533754A JP2016534342A5 JP 2016534342 A5 JP2016534342 A5 JP 2016534342A5 JP 2016533754 A JP2016533754 A JP 2016533754A JP 2016533754 A JP2016533754 A JP 2016533754A JP 2016534342 A5 JP2016534342 A5 JP 2016534342A5
- Authority
- JP
- Japan
- Prior art keywords
- particle
- transition metal
- metal ion
- target molecule
- molecules
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000002245 particle Substances 0.000 claims 30
- 229910001428 transition metal ion Inorganic materials 0.000 claims 13
- 239000000203 mixture Substances 0.000 claims 7
- 239000000758 substrate Substances 0.000 claims 7
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 claims 6
- PXHVJJICTQNCMI-UHFFFAOYSA-N Nickel Chemical compound [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 claims 6
- MUBZPKHOEPUJKR-UHFFFAOYSA-N Oxalic acid Chemical compound OC(=O)C(O)=O MUBZPKHOEPUJKR-UHFFFAOYSA-N 0.000 claims 6
- 239000002105 nanoparticle Substances 0.000 claims 6
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 claims 6
- VYZAMTAEIAYCRO-UHFFFAOYSA-N Chromium Chemical compound [Cr] VYZAMTAEIAYCRO-UHFFFAOYSA-N 0.000 claims 4
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 claims 4
- 229910052804 chromium Inorganic materials 0.000 claims 4
- 239000011651 chromium Substances 0.000 claims 4
- 239000003446 ligand Substances 0.000 claims 4
- 238000000034 method Methods 0.000 claims 4
- YGSDEFSMJLZEOE-UHFFFAOYSA-N salicylic acid Chemical compound OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 claims 4
- 229920001059 synthetic polymer Polymers 0.000 claims 4
- RIOQSEWOXXDEQQ-UHFFFAOYSA-N triphenylphosphine Chemical compound C1=CC=CC=C1P(C=1C=CC=CC=1)C1=CC=CC=C1 RIOQSEWOXXDEQQ-UHFFFAOYSA-N 0.000 claims 4
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 claims 3
- ZOKXTWBITQBERF-UHFFFAOYSA-N Molybdenum Chemical compound [Mo] ZOKXTWBITQBERF-UHFFFAOYSA-N 0.000 claims 3
- KJTLSVCANCCWHF-UHFFFAOYSA-N Ruthenium Chemical compound [Ru] KJTLSVCANCCWHF-UHFFFAOYSA-N 0.000 claims 3
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 claims 3
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 claims 3
- QCWXUUIWCKQGHC-UHFFFAOYSA-N Zirconium Chemical compound [Zr] QCWXUUIWCKQGHC-UHFFFAOYSA-N 0.000 claims 3
- 229910052782 aluminium Inorganic materials 0.000 claims 3
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 claims 3
- 150000001720 carbohydrates Chemical class 0.000 claims 3
- 235000014633 carbohydrates Nutrition 0.000 claims 3
- 239000003795 chemical substances by application Substances 0.000 claims 3
- 229910017052 cobalt Inorganic materials 0.000 claims 3
- 239000010941 cobalt Substances 0.000 claims 3
- GUTLYIVDDKVIGB-UHFFFAOYSA-N cobalt atom Chemical compound [Co] GUTLYIVDDKVIGB-UHFFFAOYSA-N 0.000 claims 3
- 229910052802 copper Inorganic materials 0.000 claims 3
- 239000010949 copper Substances 0.000 claims 3
- 229940079593 drug Drugs 0.000 claims 3
- 239000003814 drug Substances 0.000 claims 3
- 229910052742 iron Inorganic materials 0.000 claims 3
- 238000002372 labelling Methods 0.000 claims 3
- 150000002632 lipids Chemical class 0.000 claims 3
- WPBNNNQJVZRUHP-UHFFFAOYSA-L manganese(2+);methyl n-[[2-(methoxycarbonylcarbamothioylamino)phenyl]carbamothioyl]carbamate;n-[2-(sulfidocarbothioylamino)ethyl]carbamodithioate Chemical compound [Mn+2].[S-]C(=S)NCCNC([S-])=S.COC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OC WPBNNNQJVZRUHP-UHFFFAOYSA-L 0.000 claims 3
- 229910052750 molybdenum Inorganic materials 0.000 claims 3
- 239000011733 molybdenum Substances 0.000 claims 3
- 229910052759 nickel Inorganic materials 0.000 claims 3
- 229910052697 platinum Inorganic materials 0.000 claims 3
- 102000040430 polynucleotide Human genes 0.000 claims 3
- 108091033319 polynucleotide Proteins 0.000 claims 3
- 239000002157 polynucleotide Substances 0.000 claims 3
- 102000004169 proteins and genes Human genes 0.000 claims 3
- 108090000623 proteins and genes Proteins 0.000 claims 3
- 229910052703 rhodium Inorganic materials 0.000 claims 3
- 239000010948 rhodium Substances 0.000 claims 3
- MHOVAHRLVXNVSD-UHFFFAOYSA-N rhodium atom Chemical compound [Rh] MHOVAHRLVXNVSD-UHFFFAOYSA-N 0.000 claims 3
- 229910052707 ruthenium Inorganic materials 0.000 claims 3
- 229910052706 scandium Inorganic materials 0.000 claims 3
- SIXSYDAISGFNSX-UHFFFAOYSA-N scandium atom Chemical compound [Sc] SIXSYDAISGFNSX-UHFFFAOYSA-N 0.000 claims 3
- 229910052719 titanium Inorganic materials 0.000 claims 3
- 239000010936 titanium Substances 0.000 claims 3
- 229910052720 vanadium Inorganic materials 0.000 claims 3
- LEONUFNNVUYDNQ-UHFFFAOYSA-N vanadium atom Chemical compound [V] LEONUFNNVUYDNQ-UHFFFAOYSA-N 0.000 claims 3
- 229910052725 zinc Inorganic materials 0.000 claims 3
- 239000011701 zinc Substances 0.000 claims 3
- 229910052726 zirconium Inorganic materials 0.000 claims 3
- 239000005725 8-Hydroxyquinoline Substances 0.000 claims 2
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 claims 2
- CPELXLSAUQHCOX-UHFFFAOYSA-M Bromide Chemical compound [Br-] CPELXLSAUQHCOX-UHFFFAOYSA-M 0.000 claims 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 claims 2
- PIICEJLVQHRZGT-UHFFFAOYSA-N Ethylenediamine Chemical compound NCCN PIICEJLVQHRZGT-UHFFFAOYSA-N 0.000 claims 2
- KWYHDKDOAIKMQN-UHFFFAOYSA-N N,N,N',N'-tetramethylethylenediamine Chemical compound CN(C)CCN(C)C KWYHDKDOAIKMQN-UHFFFAOYSA-N 0.000 claims 2
- 229910002651 NO3 Inorganic materials 0.000 claims 2
- NHNBFGGVMKEFGY-UHFFFAOYSA-N Nitrate Chemical compound [O-][N+]([O-])=O NHNBFGGVMKEFGY-UHFFFAOYSA-N 0.000 claims 2
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 claims 2
- DGEZNRSVGBDHLK-UHFFFAOYSA-N [1,10]phenanthroline Chemical compound C1=CN=C2C3=NC=CC=C3C=CC2=C1 DGEZNRSVGBDHLK-UHFFFAOYSA-N 0.000 claims 2
- 229940037003 alum Drugs 0.000 claims 2
- NBZBKCUXIYYUSX-UHFFFAOYSA-N iminodiacetic acid Chemical compound OC(=O)CNCC(O)=O NBZBKCUXIYYUSX-UHFFFAOYSA-N 0.000 claims 2
- MGFYIUFZLHCRTH-UHFFFAOYSA-N nitrilotriacetic acid Chemical compound OC(=O)CN(CC(O)=O)CC(O)=O MGFYIUFZLHCRTH-UHFFFAOYSA-N 0.000 claims 2
- 235000006408 oxalic acid Nutrition 0.000 claims 2
- 229960003540 oxyquinoline Drugs 0.000 claims 2
- FJKROLUGYXJWQN-UHFFFAOYSA-N papa-hydroxy-benzoic acid Natural products OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 claims 2
- VLTRZXGMWDSKGL-UHFFFAOYSA-M perchlorate Inorganic materials [O-]Cl(=O)(=O)=O VLTRZXGMWDSKGL-UHFFFAOYSA-M 0.000 claims 2
- VLTRZXGMWDSKGL-UHFFFAOYSA-N perchloric acid Chemical compound OCl(=O)(=O)=O VLTRZXGMWDSKGL-UHFFFAOYSA-N 0.000 claims 2
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 claims 2
- MCJGNVYPOGVAJF-UHFFFAOYSA-N quinolin-8-ol Chemical compound C1=CN=C2C(O)=CC=CC2=C1 MCJGNVYPOGVAJF-UHFFFAOYSA-N 0.000 claims 2
- 229960004889 salicylic acid Drugs 0.000 claims 2
- 102000004190 Enzymes Human genes 0.000 claims 1
- 108090000790 Enzymes Proteins 0.000 claims 1
- -1 alum Chemical compound 0.000 claims 1
- 239000012620 biological material Substances 0.000 claims 1
- 239000000919 ceramic Substances 0.000 claims 1
- 239000002131 composite material Substances 0.000 claims 1
- 239000011521 glass Substances 0.000 claims 1
- 229910052751 metal Inorganic materials 0.000 claims 1
- 239000002184 metal Substances 0.000 claims 1
- 229910021645 metal ion Inorganic materials 0.000 claims 1
- 229910044991 metal oxide Inorganic materials 0.000 claims 1
- 150000004706 metal oxides Chemical class 0.000 claims 1
- 229910052752 metalloid Inorganic materials 0.000 claims 1
- 150000002738 metalloids Chemical class 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2013903093A AU2013903093A0 (en) | 2013-08-13 | Conjugating molecules to particles | |
| AU2013903093 | 2013-08-13 | ||
| PCT/AU2014/050181 WO2015021509A1 (en) | 2013-08-13 | 2014-08-13 | Conjugating molecules to particles |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016534342A JP2016534342A (ja) | 2016-11-04 |
| JP2016534342A5 true JP2016534342A5 (enExample) | 2017-09-21 |
| JP6479799B2 JP6479799B2 (ja) | 2019-03-06 |
Family
ID=52467859
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016533754A Active JP6479799B2 (ja) | 2013-08-13 | 2014-08-13 | 粒子への分子の接合 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US11726095B2 (enExample) |
| EP (1) | EP3033360B1 (enExample) |
| JP (1) | JP6479799B2 (enExample) |
| CN (1) | CN105452299A (enExample) |
| AU (1) | AU2014306363B2 (enExample) |
| WO (1) | WO2015021509A1 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015192183A1 (en) * | 2014-06-17 | 2015-12-23 | Anteo Technologies Pty Ltd | Hetero functional binding systems |
| WO2017027931A1 (en) * | 2015-08-20 | 2017-02-23 | Anteo Technologies Pty Ltd | Functional coating |
| AU2016358205B2 (en) * | 2015-11-20 | 2022-01-06 | Anteo Technologies Pty Ltd | Method of controlled competitive exchange |
| US11867699B2 (en) | 2016-06-10 | 2024-01-09 | The University Of Queensland | Detecting an analyte |
| JP6859215B2 (ja) * | 2017-04-17 | 2021-04-14 | 日本光電工業株式会社 | 脂質二重膜粒子またはその断片の検出方法 |
| CN108623606B (zh) * | 2018-08-02 | 2019-11-12 | 杭州中美华东制药有限公司 | 一种依鲁替尼的合成方法 |
| CN109276720B (zh) * | 2018-09-19 | 2020-10-30 | 浙江大学 | 一种金属-有机物配合物纳米材料及其制备方法和应用 |
| GB201912866D0 (en) * | 2019-09-06 | 2019-10-23 | Cambridge Molecular Diagnostics Ltd | Miltiply labelled polymetric molecule for detection assays |
| JP2023522128A (ja) * | 2020-04-08 | 2023-05-26 | アンテオ エナジー テクノロジー プロプライエタリー リミテッド | 複合粒子及びその形成方法 |
| CN111856016B (zh) * | 2020-07-29 | 2023-08-01 | 武汉生之源生物科技股份有限公司 | 一种涎液化糖链抗原测定试剂盒及其制备方法 |
| WO2023056529A1 (en) * | 2021-10-08 | 2023-04-13 | Anteo Technologies Pty Ltd | Binding support and uses thereof |
| WO2023056528A1 (en) * | 2021-10-08 | 2023-04-13 | Anteo Technologies Pty Ltd | Lateral flow assay |
| CN118986895B (zh) * | 2024-07-31 | 2025-10-24 | 山东第一医科大学附属眼科医院(山东省眼科医院) | 一种可见光催化交联的病毒样氧化钌纳米颗粒用于高效跨膜治疗圆锥角膜 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0506880A1 (en) * | 1989-12-22 | 1992-10-07 | Molecular Bioquest, Inc. | Organo-metallic coated particles for use in separations |
| CN1075817C (zh) * | 1994-07-25 | 2001-12-05 | 罗切诊断学有限公司 | 亲水的金属络合物 |
| TWI242645B (en) * | 2002-10-15 | 2005-11-01 | Ind Tech Res Inst | Biochemical labeling materials and manufacturing method |
| EP1581337A4 (en) | 2002-10-18 | 2008-05-07 | Promega Corp | COMPOSITION FOR DISCONNECTING MOLECULES |
| US7846412B2 (en) * | 2003-12-22 | 2010-12-07 | Emory University | Bioconjugated nanostructures, methods of fabrication thereof, and methods of use thereof |
| CN101421623A (zh) * | 2003-12-22 | 2009-04-29 | 爱默蕾大学 | 生物共轭的纳米结构、其制造方法、和其使用方法 |
| WO2006002472A1 (en) | 2004-07-02 | 2006-01-12 | Bio-Layer Pty Ltd | Use of metal complexes |
| WO2009139939A2 (en) * | 2008-02-22 | 2009-11-19 | The University Of North Carolina At Chapel Hill | Hybrid nanoparticles as anti-cancer therapeutic agents and dual therapeutic/imaging contrast agents |
| US10525152B2 (en) * | 2009-10-09 | 2020-01-07 | Signablok, Inc. | Methods and compositions for targeted imaging |
| WO2011046842A1 (en) * | 2009-10-12 | 2011-04-21 | The Regents Of The University Of California | Targeted nanoclusters and methods of their use |
| CN102947340A (zh) * | 2010-05-10 | 2013-02-27 | 拜欧雷耶私人有限公司 | 结合系统 |
| WO2012012748A2 (en) * | 2010-07-23 | 2012-01-26 | Luminex Corporation | Co-coupling to control reactivity of reagents in immunoassays |
| WO2015192183A1 (en) * | 2014-06-17 | 2015-12-23 | Anteo Technologies Pty Ltd | Hetero functional binding systems |
| WO2017027931A1 (en) * | 2015-08-20 | 2017-02-23 | Anteo Technologies Pty Ltd | Functional coating |
-
2014
- 2014-08-13 US US14/907,701 patent/US11726095B2/en active Active
- 2014-08-13 AU AU2014306363A patent/AU2014306363B2/en active Active
- 2014-08-13 JP JP2016533754A patent/JP6479799B2/ja active Active
- 2014-08-13 CN CN201480045394.0A patent/CN105452299A/zh active Pending
- 2014-08-13 EP EP14836721.2A patent/EP3033360B1/en active Active
- 2014-08-13 WO PCT/AU2014/050181 patent/WO2015021509A1/en not_active Ceased
-
2023
- 2023-06-28 US US18/215,323 patent/US20240053348A1/en active Pending
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