JP2016531923A5 - - Google Patents
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- JP2016531923A5 JP2016531923A5 JP2016540295A JP2016540295A JP2016531923A5 JP 2016531923 A5 JP2016531923 A5 JP 2016531923A5 JP 2016540295 A JP2016540295 A JP 2016540295A JP 2016540295 A JP2016540295 A JP 2016540295A JP 2016531923 A5 JP2016531923 A5 JP 2016531923A5
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- epc
- tissue material
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- 239000000203 mixture Substances 0.000 claims 33
- 210000002744 extracellular matrix Anatomy 0.000 claims 26
- 239000000463 material Substances 0.000 claims 26
- 210000002901 mesenchymal stem cell Anatomy 0.000 claims 20
- 102000008186 Collagen Human genes 0.000 claims 16
- 108010035532 Collagen Proteins 0.000 claims 16
- 210000000988 bone and bone Anatomy 0.000 claims 15
- 210000001519 tissue Anatomy 0.000 claims 12
- 239000012876 carrier material Substances 0.000 claims 6
- 239000007787 solid Substances 0.000 claims 6
- 230000000302 ischemic effect Effects 0.000 claims 5
- 102000010834 Extracellular Matrix Proteins Human genes 0.000 claims 4
- 108010037362 Extracellular Matrix Proteins Proteins 0.000 claims 4
- 102000003974 Fibroblast growth factor 2 Human genes 0.000 claims 4
- 108090000379 Fibroblast growth factor 2 Proteins 0.000 claims 4
- 210000004027 cell Anatomy 0.000 claims 4
- 210000004700 fetal blood Anatomy 0.000 claims 4
- 230000003511 endothelial effect Effects 0.000 claims 3
- 230000017074 necrotic cell death Effects 0.000 claims 3
- 210000001956 EPC Anatomy 0.000 claims 2
- 102000003886 Glycoproteins Human genes 0.000 claims 2
- 108090000288 Glycoproteins Proteins 0.000 claims 2
- 229920002683 Glycosaminoglycan Polymers 0.000 claims 2
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 claims 2
- 102000016611 Proteoglycans Human genes 0.000 claims 2
- 108010067787 Proteoglycans Proteins 0.000 claims 2
- 230000000735 allogeneic effect Effects 0.000 claims 2
- 210000001185 bone marrow Anatomy 0.000 claims 2
- 210000004271 bone marrow stromal cell Anatomy 0.000 claims 2
- 239000002775 capsule Substances 0.000 claims 2
- 229920001436 collagen Polymers 0.000 claims 2
- 230000001332 colony forming effect Effects 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 239000003102 growth factor Substances 0.000 claims 2
- 229920000669 heparin Polymers 0.000 claims 2
- 229960002897 heparin Drugs 0.000 claims 2
- 230000001338 necrotic effect Effects 0.000 claims 2
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical class [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 claims 2
- 238000005553 drilling Methods 0.000 claims 1
- 210000001624 hip Anatomy 0.000 claims 1
- 210000004394 hip joint Anatomy 0.000 claims 1
- 210000004767 rumen Anatomy 0.000 claims 1
- 210000000130 stem cell Anatomy 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361872828P | 2013-09-02 | 2013-09-02 | |
| US61/872,828 | 2013-09-02 | ||
| PCT/US2014/053501 WO2015031809A1 (en) | 2013-09-02 | 2014-08-29 | Cell-seeded compositions and methods useful for treating bone regions |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020037706A Division JP2020105208A (ja) | 2013-09-02 | 2020-03-05 | 骨部位を処理するために有用な細胞がシードされた組成物および方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016531923A JP2016531923A (ja) | 2016-10-13 |
| JP2016531923A5 true JP2016531923A5 (https=) | 2017-10-05 |
Family
ID=52584220
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016540295A Pending JP2016531923A (ja) | 2013-09-02 | 2014-08-29 | 骨部位を処理するために有用な細胞がシードされた組成物および方法 |
| JP2020037706A Pending JP2020105208A (ja) | 2013-09-02 | 2020-03-05 | 骨部位を処理するために有用な細胞がシードされた組成物および方法 |
| JP2022081533A Pending JP2022122293A (ja) | 2013-09-02 | 2022-05-18 | 骨部位を処理するために有用な細胞がシードされた組成物および方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020037706A Pending JP2020105208A (ja) | 2013-09-02 | 2020-03-05 | 骨部位を処理するために有用な細胞がシードされた組成物および方法 |
| JP2022081533A Pending JP2022122293A (ja) | 2013-09-02 | 2022-05-18 | 骨部位を処理するために有用な細胞がシードされた組成物および方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20150065947A1 (https=) |
| EP (1) | EP3041485B1 (https=) |
| JP (3) | JP2016531923A (https=) |
| CN (1) | CN105636600A (https=) |
| WO (1) | WO2015031809A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102012017026A1 (de) | 2012-08-28 | 2014-03-06 | Forschungszentrum Jülich GmbH | Sensor für NADP(H) und Entwicklung von Alkoholdehydrogenasen |
| US20150065425A1 (en) | 2013-09-02 | 2015-03-05 | Muffin Incorporated | Products comprising an extracellular matrix material and osteogenic protein |
| US12357469B2 (en) * | 2014-11-16 | 2025-07-15 | Spinesmith Partners, L.P. | System and method of treatment of bone lesions |
| CN105412989B (zh) | 2015-12-07 | 2018-11-02 | 杭州华迈医疗器械有限公司 | 基于脱细胞生物组织基质材料的骨修复用复合材料及其制备方法 |
| CN105311681B (zh) * | 2015-12-07 | 2018-12-25 | 杭州华迈医疗器械有限公司 | 一种可注射的骨修复用复合材料及其制备方法 |
| CN106310227A (zh) * | 2016-09-30 | 2017-01-11 | 广州赛莱拉干细胞科技股份有限公司 | 一种干细胞制剂及其制备方法和应用 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5711969A (en) * | 1995-04-07 | 1998-01-27 | Purdue Research Foundation | Large area submucosal tissue graft constructs |
| US5755791A (en) * | 1996-04-05 | 1998-05-26 | Purdue Research Foundation | Perforated submucosal tissue graft constructs |
| US5824084A (en) * | 1996-07-03 | 1998-10-20 | The Cleveland Clinic Foundation | Method of preparing a composite bone graft |
| WO2003002165A1 (en) * | 2001-06-28 | 2003-01-09 | Cook Biotech Incorporated | Graft prosthesis devices containing renal capsule collagen |
| WO2004052177A2 (en) * | 2002-12-05 | 2004-06-24 | Case Western Reserve University | Cell-based therapies for ischemia |
| CA2644508A1 (en) * | 2006-03-01 | 2007-09-07 | The Regenerative Medicine Institute | Compostions and populations of cells obtained from the umbilical cord and methods of producing the same |
| US8298528B2 (en) * | 2006-04-17 | 2012-10-30 | Hepacore Ltd. | Methods for bone regeneration using endothelial progenitor cell preparations |
| US7833270B2 (en) * | 2006-05-05 | 2010-11-16 | Warsaw Orthopedic, Inc | Implant depots to deliver growth factors to treat osteoporotic bone |
| JP2012516853A (ja) * | 2009-02-04 | 2012-07-26 | エンドジェニター テクノロジーズ，インコーポレイテッド | 分化した内皮前駆細胞の治療的使用 |
| WO2011133959A1 (en) * | 2010-04-23 | 2011-10-27 | Indiana University Research And Technology Corporation | Endothelial colony forming cells for enhancement of bone generation |
| US20130236429A1 (en) * | 2010-09-23 | 2013-09-12 | Children's Medical Center Corporation | Engineered vascular adipose tissue |
-
2014
- 2014-08-29 US US14/473,265 patent/US20150065947A1/en not_active Abandoned
- 2014-08-29 WO PCT/US2014/053501 patent/WO2015031809A1/en not_active Ceased
- 2014-08-29 CN CN201480056457.2A patent/CN105636600A/zh active Pending
- 2014-08-29 JP JP2016540295A patent/JP2016531923A/ja active Pending
- 2014-08-29 EP EP14840445.2A patent/EP3041485B1/en active Active
-
2020
- 2020-03-05 JP JP2020037706A patent/JP2020105208A/ja active Pending
-
2022
- 2022-05-18 JP JP2022081533A patent/JP2022122293A/ja active Pending
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