JP2016525147A5 - - Google Patents
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- Publication number
- JP2016525147A5 JP2016525147A5 JP2016529871A JP2016529871A JP2016525147A5 JP 2016525147 A5 JP2016525147 A5 JP 2016525147A5 JP 2016529871 A JP2016529871 A JP 2016529871A JP 2016529871 A JP2016529871 A JP 2016529871A JP 2016525147 A5 JP2016525147 A5 JP 2016525147A5
- Authority
- JP
- Japan
- Prior art keywords
- desmopressin
- combination medicament
- combination
- hours
- administered
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003814 drug Substances 0.000 claims 20
- 108010000437 Deamino Arginine Vasopressin Proteins 0.000 claims 12
- 229960004281 desmopressin Drugs 0.000 claims 12
- NFLWUMRGJYTJIN-NXBWRCJVSA-N desmopressin Chemical compound C([C@H]1C(=O)N[C@H](C(N[C@@H](CC(N)=O)C(=O)N[C@@H](CSSCCC(=O)N[C@@H](CC=2C=CC(O)=CC=2)C(=O)N1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(N)=O)=O)CCC(=O)N)C1=CC=CC=C1 NFLWUMRGJYTJIN-NXBWRCJVSA-N 0.000 claims 12
- 230000036470 plasma concentration Effects 0.000 claims 4
- 239000002677 5-alpha reductase inhibitor Substances 0.000 claims 3
- 229940113178 5 Alpha reductase inhibitor Drugs 0.000 claims 2
- 230000002686 anti-diuretic effect Effects 0.000 claims 2
- 210000002200 mouth mucosa Anatomy 0.000 claims 2
- SNEPAAKJPPNOQM-UHFFFAOYSA-N 4,8-dimethyl-1,2,5,6-tetrahydrobenzo[f]quinolizin-3-one Chemical compound C1CC2=CC(C)=CC=C2N2C1=C(C)C(=O)CC2 SNEPAAKJPPNOQM-UHFFFAOYSA-N 0.000 claims 1
- VAPSMQAHNAZRKC-PQWRYPMOSA-N Epristeride Chemical compound C1C=C2C=C(C(O)=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H](C(=O)NC(C)(C)C)[C@@]1(C)CC2 VAPSMQAHNAZRKC-PQWRYPMOSA-N 0.000 claims 1
- VMGWGDPZHXPFTC-HYBUGGRVSA-N Izonsteride Chemical compound CN([C@@H]1CCC2=C3)C(=O)CC[C@]1(C)C2=CC=C3SC(S1)=NC2=C1C=CC=C2CC VMGWGDPZHXPFTC-HYBUGGRVSA-N 0.000 claims 1
- 229960004199 dutasteride Drugs 0.000 claims 1
- JWJOTENAMICLJG-QWBYCMEYSA-N dutasteride Chemical group O=C([C@H]1CC[C@H]2[C@H]3[C@@H]([C@]4(C=CC(=O)N[C@@H]4CC3)C)CC[C@@]21C)NC1=CC(C(F)(F)F)=CC=C1C(F)(F)F JWJOTENAMICLJG-QWBYCMEYSA-N 0.000 claims 1
- 229950009537 epristeride Drugs 0.000 claims 1
- 229960004039 finasteride Drugs 0.000 claims 1
- DBEPLOCGEIEOCV-WSBQPABSSA-N finasteride Chemical compound N([C@@H]1CC2)C(=O)C=C[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H](C(=O)NC(C)(C)C)[C@@]2(C)CC1 DBEPLOCGEIEOCV-WSBQPABSSA-N 0.000 claims 1
- 229950004319 izonsteride Drugs 0.000 claims 1
- 210000002850 nasal mucosa Anatomy 0.000 claims 1
- 230000001766 physiological effect Effects 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- WMPQMBUXZHMEFZ-YJPJVVPASA-N turosteride Chemical compound CN([C@@H]1CC2)C(=O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H](C(=O)N(C(C)C)C(=O)NC(C)C)[C@@]2(C)CC1 WMPQMBUXZHMEFZ-YJPJVVPASA-N 0.000 claims 1
- 229950007816 turosteride Drugs 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361857428P | 2013-07-23 | 2013-07-23 | |
| US61/857,428 | 2013-07-23 | ||
| PCT/US2014/047897 WO2015013453A1 (en) | 2013-07-23 | 2014-07-23 | Methods and compositions comprising desmopressin in combination with a 5-alpha reductase inhibitor |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020065914A Division JP2020114858A (ja) | 2013-07-23 | 2020-04-01 | ５−α還元酵素阻害剤と組み合わせたデスモプレシンを含む方法及び組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016525147A JP2016525147A (ja) | 2016-08-22 |
| JP2016525147A5 true JP2016525147A5 (enExample) | 2017-08-31 |
Family
ID=51299054
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016529871A Pending JP2016525147A (ja) | 2013-07-23 | 2014-07-23 | ５−α還元酵素阻害剤と組み合わせたデスモプレシンを含む方法及び組成物 |
| JP2020065914A Pending JP2020114858A (ja) | 2013-07-23 | 2020-04-01 | ５−α還元酵素阻害剤と組み合わせたデスモプレシンを含む方法及び組成物 |
| JP2022114040A Pending JP2022137252A (ja) | 2013-07-23 | 2022-07-15 | ５－α還元酵素阻害剤と組み合わせたデスモプレシンを含む方法及び組成物 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020065914A Pending JP2020114858A (ja) | 2013-07-23 | 2020-04-01 | ５−α還元酵素阻害剤と組み合わせたデスモプレシンを含む方法及び組成物 |
| JP2022114040A Pending JP2022137252A (ja) | 2013-07-23 | 2022-07-15 | ５－α還元酵素阻害剤と組み合わせたデスモプレシンを含む方法及び組成物 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US9925232B2 (enExample) |
| EP (1) | EP3024473A1 (enExample) |
| JP (3) | JP2016525147A (enExample) |
| KR (3) | KR20240015736A (enExample) |
| CN (1) | CN105579056A (enExample) |
| AU (1) | AU2014293140A1 (enExample) |
| CA (1) | CA2919194A1 (enExample) |
| MX (1) | MX2016001032A (enExample) |
| WO (1) | WO2015013453A1 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105579057A (zh) | 2013-07-23 | 2016-05-11 | 阿勒根公司 | 包含与β-3-肾上腺素能受体激动剂组合的去氨加压素的方法和组合物 |
| JP2017535567A (ja) | 2014-11-20 | 2017-11-30 | アラーガン、インコーポレイテッドＡｌｌｅｒｇａｎ，Ｉｎｃｏｒｐｏｒａｔｅｄ | アルファ−アドレナリン受容体拮抗薬と組み合わせたデスモプレシンを含む方法及び組成物 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH495957A (de) | 1966-09-15 | 1970-09-15 | Ceskoslovenska Akademie Ved | Verfahren zur Herstellung eines antidiuretisch wirksamen Polypeptids |
| US3989816A (en) | 1975-06-19 | 1976-11-02 | Nelson Research & Development Company | Vehicle composition containing 1-substituted azacycloheptan-2-ones |
| US4316893A (en) | 1975-06-19 | 1982-02-23 | Nelson Research & Development Co. | Vehicle composition containing 1-substituted azacycloalkan-2-ones |
| US4505616A (en) | 1983-05-26 | 1985-03-19 | Litton Systems, Inc. | Self-locking chock system for a jack-up rig unit |
| US4557934A (en) | 1983-06-21 | 1985-12-10 | The Procter & Gamble Company | Penetrating topical pharmaceutical compositions containing 1-dodecyl-azacycloheptan-2-one |
| US5023252A (en) | 1985-12-04 | 1991-06-11 | Conrex Pharmaceutical Corporation | Transdermal and trans-membrane delivery of drugs |
| US4783450A (en) | 1987-04-13 | 1988-11-08 | Warner-Lambert Company | Use of commercial lecithin as skin penetration enhancer |
| IL101243A (en) * | 1991-03-20 | 1999-12-22 | Merck & Co Inc | Pharmaceutical preparations for the treatment of benign prostatic hyperplasia containing steroid history |
| US5534496A (en) | 1992-07-07 | 1996-07-09 | University Of Southern California | Methods and compositions to enhance epithelial drug transport |
| US7335186B2 (en) | 1998-03-13 | 2008-02-26 | Alexander George Brian O'Neil | Patient controlled drug delivery device |
| US6558695B2 (en) | 1999-12-16 | 2003-05-06 | Dermatrends, Inc. | Topical and transdermal administration of peptidyl drugs using hydroxide releasing agents as permeation enhancers |
| US7244703B2 (en) | 2001-06-22 | 2007-07-17 | Bentley Pharmaceuticals, Inc. | Pharmaceutical compositions and methods for peptide treatment |
| GB0210397D0 (en) * | 2002-05-07 | 2002-06-12 | Ferring Bv | Pharmaceutical formulations |
| US6945952B2 (en) | 2002-06-25 | 2005-09-20 | Theraject, Inc. | Solid solution perforator for drug delivery and other applications |
| EP1689419A4 (en) * | 2003-11-10 | 2009-01-14 | Reprise Biopharmaceutics Llc | PHARMACEUTICAL COMPOSITIONS COMPRISING LOW DOSAGE DESMOPRESSIN |
| ES2348303T3 (es) | 2003-12-08 | 2010-12-02 | Cpex Pharmaceuticals, Inc. | Composiciones farmacauticas y procedimientos de tratamiento con insulina. |
| CA2633570A1 (en) * | 2005-12-21 | 2007-06-28 | Pfizer Products Inc. | Pharmaceutical combination of a pde-5 inhibitor and a 5-alpha reductase inhibitor |
| CA2695634C (en) * | 2007-08-06 | 2018-01-23 | Serenity Pharmaceuticals Corporation | Methods and devices for desmopressin drug delivery |
| WO2010075327A1 (en) | 2008-12-22 | 2010-07-01 | Serenity Pharmaceuticals Corporation | Desmopressin composition |
| PT2381923T (pt) * | 2008-12-22 | 2018-11-13 | Serenity Pharmaceuticals Llc | Administração intranasal de desmopressina |
| CN102647993A (zh) * | 2009-06-18 | 2012-08-22 | 阿勒根公司 | 安全的去氨加压素给药 |
| CN105579057A (zh) | 2013-07-23 | 2016-05-11 | 阿勒根公司 | 包含与β-3-肾上腺素能受体激动剂组合的去氨加压素的方法和组合物 |
-
2014
- 2014-07-23 JP JP2016529871A patent/JP2016525147A/ja active Pending
- 2014-07-23 AU AU2014293140A patent/AU2014293140A1/en not_active Abandoned
- 2014-07-23 WO PCT/US2014/047897 patent/WO2015013453A1/en not_active Ceased
- 2014-07-23 CN CN201480052300.2A patent/CN105579056A/zh active Pending
- 2014-07-23 EP EP14748449.7A patent/EP3024473A1/en not_active Withdrawn
- 2014-07-23 KR KR1020247002754A patent/KR20240015736A/ko not_active Ceased
- 2014-07-23 MX MX2016001032A patent/MX2016001032A/es unknown
- 2014-07-23 US US14/338,567 patent/US9925232B2/en active Active
- 2014-07-23 KR KR1020217025794A patent/KR20210103590A/ko not_active Ceased
- 2014-07-23 KR KR1020167004345A patent/KR20160034366A/ko not_active Ceased
- 2014-07-23 CA CA2919194A patent/CA2919194A1/en active Pending
-
2020
- 2020-04-01 JP JP2020065914A patent/JP2020114858A/ja active Pending
-
2022
- 2022-07-15 JP JP2022114040A patent/JP2022137252A/ja active Pending
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