JP2016523537A5 - - Google Patents

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Publication number
JP2016523537A5
JP2016523537A5 JP2016522319A JP2016522319A JP2016523537A5 JP 2016523537 A5 JP2016523537 A5 JP 2016523537A5 JP 2016522319 A JP2016522319 A JP 2016522319A JP 2016522319 A JP2016522319 A JP 2016522319A JP 2016523537 A5 JP2016523537 A5 JP 2016523537A5
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JP
Japan
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sequence
human
framework region
seq
antibody
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JP2016522319A
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English (en)
Japanese (ja)
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JP6708544B2 (ja
JP2016523537A (ja
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Priority claimed from PCT/EP2014/001730 external-priority patent/WO2014206561A1/en
Publication of JP2016523537A publication Critical patent/JP2016523537A/ja
Publication of JP2016523537A5 publication Critical patent/JP2016523537A5/ja
Application granted granted Critical
Publication of JP6708544B2 publication Critical patent/JP6708544B2/ja
Active legal-status Critical Current
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JP2016522319A 2013-06-26 2014-06-26 新規抗体フレームワーク Active JP6708544B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP13003264 2013-06-26
EP13003264.2 2013-06-26
PCT/EP2014/001730 WO2014206561A1 (en) 2013-06-26 2014-06-26 Novel antibody frameworks

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2019111990A Division JP2019201643A (ja) 2013-06-26 2019-06-17 新規抗体フレームワーク

Publications (3)

Publication Number Publication Date
JP2016523537A JP2016523537A (ja) 2016-08-12
JP2016523537A5 true JP2016523537A5 (https=) 2018-01-18
JP6708544B2 JP6708544B2 (ja) 2020-06-10

Family

ID=48699516

Family Applications (4)

Application Number Title Priority Date Filing Date
JP2016522319A Active JP6708544B2 (ja) 2013-06-26 2014-06-26 新規抗体フレームワーク
JP2019111990A Withdrawn JP2019201643A (ja) 2013-06-26 2019-06-17 新規抗体フレームワーク
JP2021169020A Pending JP2022028659A (ja) 2013-06-26 2021-10-14 新規抗体フレームワーク
JP2023199881A Pending JP2024026176A (ja) 2013-06-26 2023-11-27 新規抗体フレームワーク

Family Applications After (3)

Application Number Title Priority Date Filing Date
JP2019111990A Withdrawn JP2019201643A (ja) 2013-06-26 2019-06-17 新規抗体フレームワーク
JP2021169020A Pending JP2022028659A (ja) 2013-06-26 2021-10-14 新規抗体フレームワーク
JP2023199881A Pending JP2024026176A (ja) 2013-06-26 2023-11-27 新規抗体フレームワーク

Country Status (12)

Country Link
US (3) US10174102B2 (https=)
EP (1) EP3013864A1 (https=)
JP (4) JP6708544B2 (https=)
KR (4) KR20240000622A (https=)
CN (2) CN113943366B (https=)
AU (2) AU2014301629B2 (https=)
CA (1) CA2914829A1 (https=)
HK (1) HK1218549A1 (https=)
IL (3) IL243311B (https=)
NZ (1) NZ714320A (https=)
SG (2) SG11201509899PA (https=)
WO (1) WO2014206561A1 (https=)

Families Citing this family (24)

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Publication number Priority date Publication date Assignee Title
EP3013864A1 (en) 2013-06-26 2016-05-04 Numab AG Novel antibody frameworks
EP3307776A1 (en) 2015-06-15 2018-04-18 Numab Innovation AG Hetero-dimeric multi-specific antibody format
KR20190003938A (ko) 2016-02-25 2019-01-10 셀 메디카 스위처란트 아게 면역치료를 위한 변형된 세포
SMT202000706T1 (it) 2016-03-17 2021-01-05 Tillotts Pharma Ag Anticorpi anti-tnf alfa e frammenti funzionali di essi
EP3219727B1 (en) 2016-03-17 2020-12-16 Tillotts Pharma AG Anti-tnf alpha-antibodies and functional fragments thereof
CN108884156B (zh) 2016-03-17 2021-10-01 努玛创新有限公司 抗TNFα抗体及其功能片段
WO2017158084A1 (en) 2016-03-17 2017-09-21 Numab Innovation Ag ANTI-TNFα-ANTIBODIES AND FUNCTIONAL FRAGMENTS THEREOF
JP6978427B2 (ja) 2016-03-17 2021-12-08 ヌマブ セラピューティクス アクチェンゲゼルシャフト 抗TNFα抗体とその機能性フラグメント
GB201621591D0 (en) * 2016-12-19 2017-02-01 Ucb Biopharma Sprl Antibody molecules and method
WO2018224441A1 (en) 2017-06-05 2018-12-13 Numab Innovation Ag Novel anti-cd3 antibodies
JP7247110B2 (ja) 2017-06-05 2023-03-28 ヌマブ セラピューティクス アクチェンゲゼルシャフト 新規抗cd3抗体
ES3015094T3 (en) * 2017-06-05 2025-04-29 Numab Therapeutics AG Anti-hsa antibodies
ES2967739T3 (es) 2017-06-05 2024-05-03 Numab Therapeutics AG Formato de anticuerpo heterodimérico multiespecífico dirigido al menos a CD3 y a HSA
WO2018224439A1 (en) 2017-06-05 2018-12-13 Numab Innovation Ag Novel anti-hsa antibodies
CN116948035A (zh) * 2017-06-25 2023-10-27 西雅图免疫公司 多特异性抗体及其制备和使用方法
SG11201912865VA (en) * 2017-06-25 2020-01-30 Systimmune Inc Multi-specific antibodies and methods of making and using thereof
EP3459968A1 (en) * 2017-09-20 2019-03-27 Numab Innovation AG Novel stable antibody variable domain framework combinations
EP3689907A1 (en) 2019-01-31 2020-08-05 Numab Therapeutics AG Antibodies targeting il-17a and methods of use thereof
JP7525499B2 (ja) 2019-01-31 2024-07-30 ヌマブ セラピューティクス アクチェンゲゼルシャフト TNFα及びIL-17Aに対する特異性を有する多重特異性抗体、IL-17Aを標的とする抗体、及びそれらの使用方法
EP4271413A4 (en) * 2020-12-30 2025-07-30 Ascendo Biotechnology Inc MONOCLONAL ANTIBODY AGAINST HUMAN MAC-1 AND ITS USES
CN116848136A (zh) 2021-02-12 2023-10-03 勃林格殷格翰国际有限公司 补体c3抗原结合蛋白
WO2022192625A1 (en) 2021-03-11 2022-09-15 IgGenix, Inc. Methods and systems for predicting allergic response
IL313655A (en) 2021-12-22 2024-08-01 Boehringer Ingelheim Int Anti-C3 antibodies and their antigen-binding fragments and their uses for the treatment of eyes or eye diseases
CN120882418A (zh) * 2022-11-04 2025-10-31 MiNK治疗公司 B细胞成熟抗原(bcma)嵌合抗原受体不变自然杀伤t细胞及其用途

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DE19819846B4 (de) 1998-05-05 2016-11-24 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Multivalente Antikörper-Konstrukte
EP1651659A4 (en) 2003-08-07 2008-09-17 Epitomics Inc METHOD FOR HUMANIZATION OF MONOCLONAL RABBIT ANTIBODIES
WO2008004834A1 (en) 2006-07-06 2008-01-10 Isu Abxis Co., Ltd Humanized monoclonal antibody highly binding to epidermal growth factor receptor, egf receptor
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MX345039B (es) * 2008-06-25 2017-01-16 Esbatech Alcon Biomed Res Unit Anticuerpos estables y solubles que inhiben el tnfa.
LT3216803T (lt) 2008-06-25 2020-06-10 Novartis Ag Stabilūs ir tirpūs antikūnai, slopinantys vegf
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EP3013864A1 (en) 2013-06-26 2016-05-04 Numab AG Novel antibody frameworks
EP3459968A1 (en) * 2017-09-20 2019-03-27 Numab Innovation AG Novel stable antibody variable domain framework combinations

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