JP2016519110A5 - - Google Patents
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- Publication number
- JP2016519110A5 JP2016519110A5 JP2016509148A JP2016509148A JP2016519110A5 JP 2016519110 A5 JP2016519110 A5 JP 2016519110A5 JP 2016509148 A JP2016509148 A JP 2016509148A JP 2016509148 A JP2016509148 A JP 2016509148A JP 2016519110 A5 JP2016519110 A5 JP 2016519110A5
- Authority
- JP
- Japan
- Prior art keywords
- veterinary
- administration
- core protein
- disease
- decorin core
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 102000004237 Decorin Human genes 0.000 claims 24
- 108090000738 Decorin Proteins 0.000 claims 24
- 101710132601 Capsid protein Proteins 0.000 claims 19
- 230000006378 damage Effects 0.000 claims 16
- 208000027418 Wounds and injury Diseases 0.000 claims 14
- 206010052428 Wound Diseases 0.000 claims 8
- 208000014674 injury Diseases 0.000 claims 8
- 108010076504 Protein Sorting Signals Proteins 0.000 claims 6
- 201000010099 disease Diseases 0.000 claims 6
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 6
- 230000035772 mutation Effects 0.000 claims 5
- 208000029523 Interstitial Lung disease Diseases 0.000 claims 4
- 206010028980 Neoplasm Diseases 0.000 claims 4
- 201000011510 cancer Diseases 0.000 claims 4
- 208000019425 cirrhosis of liver Diseases 0.000 claims 4
- 238000001356 surgical procedure Methods 0.000 claims 4
- 239000013604 expression vector Substances 0.000 claims 3
- 239000000203 mixture Substances 0.000 claims 3
- 235000018102 proteins Nutrition 0.000 claims 3
- 102000004169 proteins and genes Human genes 0.000 claims 3
- 108090000623 proteins and genes Proteins 0.000 claims 3
- 241000283690 Bos taurus Species 0.000 claims 2
- 208000007342 Diabetic Nephropathies Diseases 0.000 claims 2
- 102000001301 EGF receptor Human genes 0.000 claims 2
- 108060006698 EGF receptor Proteins 0.000 claims 2
- 208000035874 Excoriation Diseases 0.000 claims 2
- 208000001860 Eye Infections Diseases 0.000 claims 2
- 206010015911 Eye burns Diseases 0.000 claims 2
- 206010016654 Fibrosis Diseases 0.000 claims 2
- 108010031794 IGF Type 1 Receptor Proteins 0.000 claims 2
- 102100039688 Insulin-like growth factor 1 receptor Human genes 0.000 claims 2
- 206010023330 Keloid scar Diseases 0.000 claims 2
- 102000004407 Lactalbumin Human genes 0.000 claims 2
- 108090000942 Lactalbumin Proteins 0.000 claims 2
- 208000019693 Lung disease Diseases 0.000 claims 2
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 2
- 238000005299 abrasion Methods 0.000 claims 2
- 125000003275 alpha amino acid group Chemical group 0.000 claims 2
- 235000001014 amino acid Nutrition 0.000 claims 2
- 208000029028 brain injury Diseases 0.000 claims 2
- 230000007882 cirrhosis Effects 0.000 claims 2
- 239000002537 cosmetic Substances 0.000 claims 2
- 208000033679 diabetic kidney disease Diseases 0.000 claims 2
- 208000011323 eye infectious disease Diseases 0.000 claims 2
- 238000005469 granulation Methods 0.000 claims 2
- 230000003179 granulation Effects 0.000 claims 2
- 208000019622 heart disease Diseases 0.000 claims 2
- 238000007918 intramuscular administration Methods 0.000 claims 2
- 238000007913 intrathecal administration Methods 0.000 claims 2
- 238000001990 intravenous administration Methods 0.000 claims 2
- 208000017169 kidney disease Diseases 0.000 claims 2
- 208000019423 liver disease Diseases 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 210000005036 nerve Anatomy 0.000 claims 2
- 150000007523 nucleic acids Chemical group 0.000 claims 2
- 201000002793 renal fibrosis Diseases 0.000 claims 2
- 230000036573 scar formation Effects 0.000 claims 2
- 208000020431 spinal cord injury Diseases 0.000 claims 2
- 238000007920 subcutaneous administration Methods 0.000 claims 2
- 230000000699 topical effect Effects 0.000 claims 2
- 230000008733 trauma Effects 0.000 claims 2
- QNAYBMKLOCPYGJ-REOHCLBHSA-N L-alanine Chemical compound C[C@H](N)C(O)=O QNAYBMKLOCPYGJ-REOHCLBHSA-N 0.000 claims 1
- MTCFGRXMJLQNBG-UHFFFAOYSA-N Serine Natural products OCC(N)C(O)=O MTCFGRXMJLQNBG-UHFFFAOYSA-N 0.000 claims 1
- 235000004279 alanine Nutrition 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 239000003889 eye drop Substances 0.000 claims 1
- 229940012356 eye drops Drugs 0.000 claims 1
- 238000009472 formulation Methods 0.000 claims 1
- 239000000499 gel Substances 0.000 claims 1
- 239000007788 liquid Substances 0.000 claims 1
- 239000006210 lotion Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000002674 ointment Substances 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 239000000843 powder Substances 0.000 claims 1
- 239000007921 spray Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361814405P | 2013-04-22 | 2013-04-22 | |
| US61/814,405 | 2013-04-22 | ||
| PCT/US2014/034877 WO2014176198A1 (en) | 2013-04-22 | 2014-04-22 | Veterinary decorin compositions and use thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016519110A JP2016519110A (ja) | 2016-06-30 |
| JP2016519110A5 true JP2016519110A5 (enExample) | 2017-06-15 |
Family
ID=51729463
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016509148A Pending JP2016519110A (ja) | 2013-04-22 | 2014-04-22 | 獣医学的デコリン組成物及びそれらの使用 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US10137168B2 (enExample) |
| EP (1) | EP2989208A4 (enExample) |
| JP (1) | JP2016519110A (enExample) |
| AU (1) | AU2014257267B2 (enExample) |
| CA (1) | CA2907944C (enExample) |
| WO (1) | WO2014176198A1 (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PE20251064A1 (es) * | 2022-04-28 | 2025-04-09 | Biocad Joint Stock Co | Acido nucleico aislado que codifica una proteina de fusion basada en fviii-bdd y en un peptido senal heterologo, y uso de la misma |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6509314B1 (en) * | 1988-06-28 | 2003-01-21 | The Burnham Institute | Methods of preventing or reducing scarring with decorin or biglycan |
| US5583103A (en) | 1988-06-28 | 1996-12-10 | La Jolla Cancer Research Foundation | Inhibition of transforming growth factor beta activity |
| US5654270A (en) | 1988-06-28 | 1997-08-05 | La Jolla Cancer Research Foundation | Use of fibromodulin to prevent or reduce dermal scarring |
| FI906411A7 (fi) | 1988-06-28 | 1990-12-27 | La Jolla Cancer Res Foundation | Solujen lisääntymisen esto Decorinilla |
| WO1993009800A1 (en) * | 1991-11-14 | 1993-05-27 | La Jolla Cancer Research Foundation | Inhibitors of cell regulatory factors and methods for preventing or reducing scarring |
| US6524573B1 (en) | 1997-12-30 | 2003-02-25 | Thomas Jefferson University | Method of suppressing tumor cell growth by administering a decorin gene or gene product |
| US6673341B2 (en) | 1998-07-06 | 2004-01-06 | Beth Israel Deaconness Medical Center | Methods of inhibiting proliferative diseases by inhibiting TGF-β-mediated angiogenesis |
| BR0110577A (pt) | 2000-05-05 | 2003-12-30 | Gtc Biotherapeutics Inc | Decorina transgenicamente produzida |
| US20040033493A1 (en) * | 2001-01-31 | 2004-02-19 | Tchernev Velizar T. | Proteins and nucleic acids encoding same |
| EP2686335B1 (en) | 2011-03-14 | 2018-04-25 | Catalent Pharma Solutions, LLC | Decorin compositions and use thereof |
-
2014
- 2014-04-22 CA CA2907944A patent/CA2907944C/en active Active
- 2014-04-22 WO PCT/US2014/034877 patent/WO2014176198A1/en not_active Ceased
- 2014-04-22 US US14/258,197 patent/US10137168B2/en active Active
- 2014-04-22 AU AU2014257267A patent/AU2014257267B2/en active Active
- 2014-04-22 JP JP2016509148A patent/JP2016519110A/ja active Pending
- 2014-04-22 EP EP14788633.7A patent/EP2989208A4/en not_active Ceased
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