JP2016513532A5 - - Google Patents
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- Publication number
- JP2016513532A5 JP2016513532A5 JP2016500561A JP2016500561A JP2016513532A5 JP 2016513532 A5 JP2016513532 A5 JP 2016513532A5 JP 2016500561 A JP2016500561 A JP 2016500561A JP 2016500561 A JP2016500561 A JP 2016500561A JP 2016513532 A5 JP2016513532 A5 JP 2016513532A5
- Authority
- JP
- Japan
- Prior art keywords
- film layer
- property
- composition
- time interval
- therapeutic agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000010410 layer Substances 0.000 claims 37
- 239000000203 mixture Substances 0.000 claims 11
- 239000003814 drug Substances 0.000 claims 8
- 229940124597 therapeutic agent Drugs 0.000 claims 8
- 239000003125 aqueous solvent Substances 0.000 claims 6
- 239000007787 solid Substances 0.000 claims 6
- 108010049003 Fibrinogen Proteins 0.000 claims 5
- 102000008946 Fibrinogen Human genes 0.000 claims 5
- 229940012952 fibrinogen Drugs 0.000 claims 5
- 239000003795 chemical substances by application Substances 0.000 claims 4
- 238000000034 method Methods 0.000 claims 2
- 239000002086 nanomaterial Substances 0.000 claims 2
- 230000003746 surface roughness Effects 0.000 claims 2
- 102000009123 Fibrin Human genes 0.000 claims 1
- 108010073385 Fibrin Proteins 0.000 claims 1
- BWGVNKXGVNDBDI-UHFFFAOYSA-N Fibrin monomer Chemical compound CNC(=O)CNC(=O)CN BWGVNKXGVNDBDI-UHFFFAOYSA-N 0.000 claims 1
- 229940121948 Muscarinic receptor antagonist Drugs 0.000 claims 1
- 108090000190 Thrombin Proteins 0.000 claims 1
- 239000013566 allergen Substances 0.000 claims 1
- 239000003242 anti bacterial agent Substances 0.000 claims 1
- 229940121363 anti-inflammatory agent Drugs 0.000 claims 1
- 239000002260 anti-inflammatory agent Substances 0.000 claims 1
- 230000001028 anti-proliverative effect Effects 0.000 claims 1
- 239000003146 anticoagulant agent Substances 0.000 claims 1
- 239000000739 antihistaminic agent Substances 0.000 claims 1
- 229940125715 antihistaminic agent Drugs 0.000 claims 1
- 229940030600 antihypertensive agent Drugs 0.000 claims 1
- 239000002220 antihypertensive agent Substances 0.000 claims 1
- 229960004676 antithrombotic agent Drugs 0.000 claims 1
- 239000003443 antiviral agent Substances 0.000 claims 1
- 159000000007 calcium salts Chemical class 0.000 claims 1
- 239000000812 cholinergic antagonist Substances 0.000 claims 1
- 239000002872 contrast media Substances 0.000 claims 1
- 238000001035 drying Methods 0.000 claims 1
- 229950003499 fibrin Drugs 0.000 claims 1
- 239000003102 growth factor Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000004014 plasticizer Substances 0.000 claims 1
- 239000011241 protective layer Substances 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 238000011084 recovery Methods 0.000 claims 1
- 229960004072 thrombin Drugs 0.000 claims 1
- 108700026220 vif Genes Proteins 0.000 claims 1
- 229940088594 vitamin Drugs 0.000 claims 1
- 239000011782 vitamin Substances 0.000 claims 1
- 229930003231 vitamin Natural products 0.000 claims 1
- 235000013343 vitamin Nutrition 0.000 claims 1
- 150000003722 vitamin derivatives Chemical class 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13/794,355 | 2013-03-11 | ||
| US13/794,355 US9271925B2 (en) | 2013-03-11 | 2013-03-11 | Multi-layer biodegradable device having adjustable drug release profile |
| PCT/US2014/020021 WO2014164027A1 (en) | 2013-03-11 | 2014-03-03 | Multi-layer biodegradable device having adjustable drug release profile |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016513532A JP2016513532A (ja) | 2016-05-16 |
| JP2016513532A5 true JP2016513532A5 (enExample) | 2017-04-06 |
| JP6542190B2 JP6542190B2 (ja) | 2019-07-10 |
Family
ID=50382608
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016500561A Expired - Fee Related JP6542190B2 (ja) | 2013-03-11 | 2014-03-03 | 調節可能な薬物放出プロファイルを有する多層式生分解性器具 |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US9271925B2 (enExample) |
| EP (1) | EP2968691A1 (enExample) |
| JP (1) | JP6542190B2 (enExample) |
| CN (1) | CN105209086B (enExample) |
| AU (1) | AU2014249723B2 (enExample) |
| CA (1) | CA2903373A1 (enExample) |
| WO (1) | WO2014164027A1 (enExample) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2477617B1 (en) | 2009-09-18 | 2018-01-31 | Bioinspire Technologies Inc. | Free-standing biodegradable patch |
| US9271925B2 (en) | 2013-03-11 | 2016-03-01 | Bioinspire Technologies, Inc. | Multi-layer biodegradable device having adjustable drug release profile |
| GB201505527D0 (en) | 2015-03-31 | 2015-05-13 | Jmedtech Pte Ltd | Composition |
| US10159586B2 (en) | 2015-06-29 | 2018-12-25 | 480 Biomedical Inc. | Scaffold loading and delivery systems |
| US20160374800A1 (en) | 2015-06-29 | 2016-12-29 | Changcheng You | Implantable scaffolds for treatment of sinusitis |
| US10232082B2 (en) | 2015-06-29 | 2019-03-19 | 480 Biomedical, Inc. | Implantable scaffolds for treatment of sinusitis |
| US10973664B2 (en) | 2015-12-30 | 2021-04-13 | Lyra Therapeutics, Inc. | Scaffold loading and delivery systems |
| EP3419679A1 (en) * | 2016-02-22 | 2019-01-02 | The Methodist Hospital | Implantable drug delivery systems |
| EP3518844A4 (en) * | 2016-09-30 | 2020-05-27 | Lynthera Corporation | HIGH PRECISION DRUG DELIVERY THROUGH A DUAL DOMAIN EYE DEVICE |
| KR101837304B1 (ko) * | 2016-11-15 | 2018-03-12 | 고려대학교 산학협력단 | 다중약물이 포함된 생분해성 패치 |
| US20180200494A1 (en) * | 2017-01-18 | 2018-07-19 | Bioinspire Technologies, Inc. | Devices, systems, and methods for delivering therapeutic substances in a mammalian body |
| US10201639B2 (en) | 2017-05-01 | 2019-02-12 | 480 Biomedical, Inc. | Drug-eluting medical implants |
| EP3681487B1 (en) * | 2017-09-14 | 2024-07-10 | Allvivo Vascular, Inc. | Self adhesive film for delivery of actives |
| EP3691618A1 (en) | 2017-10-06 | 2020-08-12 | Foundry Therapeutics, Inc. | Implantable depots for the controlled release of therapeutic agents |
| CN116650732A (zh) * | 2018-01-08 | 2023-08-29 | 铸造疗法股份有限公司 | 经由治疗剂的控制递送用于治疗腔内癌症的装置、系统和方法 |
| CN111936175A (zh) * | 2018-01-15 | 2020-11-13 | 持田制药株式会社 | 防粘连用组合物 |
| US12458589B2 (en) | 2018-05-12 | 2025-11-04 | Foundry Therapeutics, Inc. | Implantable polymer depots for the controlled release of therapeutic agents |
| EP3843710A1 (en) | 2018-08-28 | 2021-07-07 | Foundry Therapeutics, Inc. | Polymer implants |
| US12403291B2 (en) * | 2019-08-30 | 2025-09-02 | Intersect Ent, Inc. | Submucosal bioresorbable drug eluting platform |
| WO2021151156A1 (en) * | 2020-01-31 | 2021-08-05 | Anders William James Sideris | Drug delivery device |
| CN111789711B (zh) * | 2020-08-10 | 2024-10-29 | 西南医科大学 | 内镜下治疗胃溃疡的敷料装置 |
| CN119732794B (zh) * | 2024-12-26 | 2026-02-17 | 江南大学 | 一种双载药负泊松比织物敷料及其制备方法 |
Family Cites Families (72)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT359652B (de) | 1979-02-15 | 1980-11-25 | Immuno Ag | Verfahren zur herstellung eines gewebekleb- stoffes |
| AT359653B (de) | 1979-02-15 | 1980-11-25 | Immuno Ag | Verfahren zur herstellung eines gewebekleb- stoffes |
| DE3105624A1 (de) | 1981-02-16 | 1982-09-02 | Hormon-Chemie München GmbH, 8000 München | Material zum abdichten und heilen von wunden |
| US4548736A (en) | 1983-08-29 | 1985-10-22 | Wisconsin Alumni Research Foundation | Preparation of protein films |
| US4560374A (en) | 1983-10-17 | 1985-12-24 | Hammerslag Julius G | Method for repairing stenotic vessels |
| US4577631A (en) | 1984-11-16 | 1986-03-25 | Kreamer Jeffry W | Aneurysm repair apparatus and method |
| US5223420A (en) | 1985-03-01 | 1993-06-29 | Institut National De La Sante Et De La Recherche Medicale | Elastin-based product, a procedure for its preparation and its biological applications; in particular as biomaterials and artificial supports |
| US5843156A (en) | 1988-08-24 | 1998-12-01 | Endoluminal Therapeutics, Inc. | Local polymeric gel cellular therapy |
| US5213580A (en) | 1988-08-24 | 1993-05-25 | Endoluminal Therapeutics, Inc. | Biodegradable polymeric endoluminal sealing process |
| US5634946A (en) | 1988-08-24 | 1997-06-03 | Focal, Inc. | Polymeric endoluminal paving process |
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| US5487897A (en) | 1989-07-24 | 1996-01-30 | Atrix Laboratories, Inc. | Biodegradable implant precursor |
| US5092841A (en) | 1990-05-17 | 1992-03-03 | Wayne State University | Method for treating an arterial wall injured during angioplasty |
| US6054122A (en) | 1990-11-27 | 2000-04-25 | The American National Red Cross | Supplemented and unsupplemented tissue sealants, methods of their production and use |
| AU1461592A (en) | 1991-02-07 | 1992-09-07 | Fibratek, Inc. | Fibrinogen based adhesive |
| US5510077A (en) | 1992-03-19 | 1996-04-23 | Dinh; Thomas Q. | Method of making an intraluminal stent |
| US5591224A (en) | 1992-03-19 | 1997-01-07 | Medtronic, Inc. | Bioelastomeric stent |
| US5599352A (en) | 1992-03-19 | 1997-02-04 | Medtronic, Inc. | Method of making a drug eluting stent |
| JP3739411B2 (ja) | 1992-09-08 | 2006-01-25 | 敬二 伊垣 | 脈管ステント及びその製造方法並びに脈管ステント装置 |
| US5942278A (en) | 1993-03-31 | 1999-08-24 | Nycomed Arzneimittel Gmbh | Process for the production of a material for sealing and healing wounds |
| US6177126B1 (en) | 1993-03-31 | 2001-01-23 | Nycomed Arzneimittel Gmbh | Process for the production of a material for sealing and healing wounds |
| US5599307A (en) | 1993-07-26 | 1997-02-04 | Loyola University Of Chicago | Catheter and method for the prevention and/or treatment of stenotic processes of vessels and cavities |
| ES2172573T3 (es) | 1993-12-01 | 2002-10-01 | Bioartificial Gel Technologies Inc | Hidrogel basado en albumina. |
| US5792106A (en) | 1993-12-02 | 1998-08-11 | Scimed Life Systems, Inc. | In situ stent forming catheter |
| EP0748215B1 (en) | 1994-02-17 | 2003-05-28 | New York Blood Center, Inc. | Biologic bioadhesive compositions containing fibrin glue and liposomes, methods of preparation and use |
| ATE310839T1 (de) | 1994-04-29 | 2005-12-15 | Scimed Life Systems Inc | Stent mit kollagen |
| US6074663A (en) | 1995-01-16 | 2000-06-13 | Baxter International Inc. | Method of using cross-linked fibrin material |
| US6965014B1 (en) | 1996-01-16 | 2005-11-15 | Baxter International Inc. | Fibrin material and method for producing and using the same |
| US5634936A (en) | 1995-02-06 | 1997-06-03 | Scimed Life Systems, Inc. | Device for closing a septal defect |
| US20020095218A1 (en) | 1996-03-12 | 2002-07-18 | Carr Robert M. | Tissue repair fabric |
| US5702715A (en) | 1995-10-27 | 1997-12-30 | Drying Technology | Reinforced biological sealants |
| WO1997028832A1 (en) | 1996-02-06 | 1997-08-14 | New Generation Medical Corporation | Composition for sealing wounds |
| HUP9903586A3 (en) | 1996-04-04 | 2003-02-28 | Baxter Ag | Hemostatic sponge based on collagen |
| WO1998012274A1 (en) | 1996-09-23 | 1998-03-26 | Chandrashekar Pathak | Methods and devices for preparing protein concentrates |
| US5899917A (en) | 1997-03-12 | 1999-05-04 | Cardiosynopsis, Inc. | Method for forming a stent in situ |
| JP4480270B2 (ja) * | 1998-05-19 | 2010-06-16 | ジ・アメリカン・ナショナル・レッド・クロス | 止血サンドウィッチ包帯 |
| US6605294B2 (en) | 1998-08-14 | 2003-08-12 | Incept Llc | Methods of using in situ hydration of hydrogel articles for sealing or augmentation of tissue or vessels |
| US7662409B2 (en) | 1998-09-25 | 2010-02-16 | Gel-Del Technologies, Inc. | Protein matrix materials, devices and methods of making and using thereof |
| US7572769B2 (en) | 1998-12-23 | 2009-08-11 | Csl Behring Gmbh | Fibrin adhesive granulate and method for its preparation |
| US6312457B1 (en) | 1999-04-01 | 2001-11-06 | Boston Scientific Corporation | Intraluminal lining |
| US6296607B1 (en) | 2000-10-20 | 2001-10-02 | Praxis, Llc. | In situ bulking device |
| US7098315B2 (en) | 2001-01-25 | 2006-08-29 | Nycomed Pharma As | Method of preparing a collagen sponge, a device for extracting a part of a collagen foam, and an elongated collagen sponge |
| PL206194B1 (pl) | 2001-01-25 | 2010-07-30 | Nycomed Pharma Asnycomed Pharma As | Sposób wytwarzania zawiesiny cząstek fibrynogenu i trombiny, zawiesina zawierająca fibrynogen, trombinę i alkohol oraz sposób powlekania nośnika taką zawiesiną |
| DE10105592A1 (de) | 2001-02-06 | 2002-08-08 | Achim Goepferich | Platzhalter zur Arzneistofffreigabe in der Stirnhöhle |
| US7052713B2 (en) | 2001-02-13 | 2006-05-30 | Nycomed Pharma As | Carrier with solid fibrinogen and solid thrombin |
| US6893431B2 (en) | 2001-10-15 | 2005-05-17 | Scimed Life Systems, Inc. | Medical device for delivering patches |
| WO2003093433A2 (en) | 2002-05-02 | 2003-11-13 | Regents Of The University Of Minnesota | Fibrin-based biomatrix |
| JP4777650B2 (ja) * | 2002-09-10 | 2011-09-21 | アメリカン ナショナル レッド クロス | 止血用包帯 |
| AU2004222340B2 (en) | 2003-03-14 | 2009-11-12 | Intersect Ent, Inc. | Sinus delivery of sustained release therapeutics |
| MXPA05010692A (es) | 2003-04-04 | 2006-04-18 | Tissuemed Ltd | Formulaciones que se adhieren a tejido. |
| US20050032205A1 (en) | 2003-08-05 | 2005-02-10 | Smith Sidney T. | In vitro cell culture employing a fibrin network in a flexible gas permeable container |
| WO2005046746A2 (en) | 2003-11-10 | 2005-05-26 | Angiotech International Ag | Medical implants and fibrosis-inducing agents |
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| US7803150B2 (en) | 2004-04-21 | 2010-09-28 | Acclarent, Inc. | Devices, systems and methods useable for treating sinusitis |
| US7361168B2 (en) | 2004-04-21 | 2008-04-22 | Acclarent, Inc. | Implantable device and methods for delivering drugs and other substances to treat sinusitis and other disorders |
| US7402172B2 (en) | 2004-10-13 | 2008-07-22 | Boston Scientific Scimed, Inc. | Intraluminal therapeutic patch |
| KR100785378B1 (ko) | 2005-09-05 | 2007-12-14 | 주식회사 바이오레인 | 다층구조의 유착방지제 |
| WO2007035726A2 (en) | 2005-09-19 | 2007-03-29 | Mayo Foundation For Medical Education And Research | Implantable closure apparatus and methods |
| US7597882B2 (en) | 2006-04-24 | 2009-10-06 | Incept Llc | Protein crosslinkers, crosslinking methods and applications thereof |
| US7951194B2 (en) | 2006-05-26 | 2011-05-31 | Abbott Cardiovascular Sysetms Inc. | Bioabsorbable stent with radiopaque coating |
| US8445009B2 (en) | 2006-08-04 | 2013-05-21 | Stb, Ltd | Processes for the production of solid dressings for treating wounded tissue |
| WO2008094659A2 (en) | 2007-01-31 | 2008-08-07 | Allergan, Inc. | Novel biomaterials for ocular drug delivery and a method for making and using same |
| US8221783B2 (en) | 2007-09-10 | 2012-07-17 | Boston Scientific Scimed, Inc. | Medical devices with triggerable bioadhesive material |
| WO2009088726A2 (en) | 2007-12-31 | 2009-07-16 | Acclarent, Inc. | Mucosal tissue dressing and method of use |
| CA2732355A1 (en) | 2008-08-01 | 2010-02-04 | Intersect Ent, Inc. | Methods and devices for crimping self-expanding devices |
| CN102458272B (zh) | 2009-04-27 | 2014-09-17 | 因特尔赛克特耳鼻喉公司 | 治疗与扁桃体切除术相关的疼痛的装置 |
| DK2435102T3 (da) * | 2009-05-28 | 2020-10-19 | Addbio Ab | Flerlagsproteinfilm, fremstillingsfremgangsmåder og lægemiddelafgivelsesindretninger samt biomedicinske implantater med anvendelse af filmene |
| EP2442834A2 (en) | 2009-06-15 | 2012-04-25 | Technion Research and Development Foundation, Ltd. | Reinforced surgical adhesives and sealants and their in-situ application |
| US9271925B2 (en) * | 2013-03-11 | 2016-03-01 | Bioinspire Technologies, Inc. | Multi-layer biodegradable device having adjustable drug release profile |
| EP2477617B1 (en) | 2009-09-18 | 2018-01-31 | Bioinspire Technologies Inc. | Free-standing biodegradable patch |
| WO2012149494A2 (en) | 2011-04-27 | 2012-11-01 | Massachusetts Institute Of Technology | Coating compositions, methods and coated devices |
-
2013
- 2013-03-11 US US13/794,355 patent/US9271925B2/en not_active Expired - Fee Related
-
2014
- 2014-03-03 WO PCT/US2014/020021 patent/WO2014164027A1/en not_active Ceased
- 2014-03-03 CN CN201480024863.0A patent/CN105209086B/zh not_active Expired - Fee Related
- 2014-03-03 JP JP2016500561A patent/JP6542190B2/ja not_active Expired - Fee Related
- 2014-03-03 EP EP14712868.0A patent/EP2968691A1/en not_active Withdrawn
- 2014-03-03 CA CA2903373A patent/CA2903373A1/en not_active Abandoned
- 2014-03-03 AU AU2014249723A patent/AU2014249723B2/en not_active Ceased
-
2016
- 2016-02-17 US US15/046,285 patent/US9682174B2/en not_active Expired - Fee Related
-
2017
- 2017-06-15 US US15/624,304 patent/US10159768B2/en not_active Expired - Fee Related
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