JP2016513075A5 - - Google Patents
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- Publication number
- JP2016513075A5 JP2016513075A5 JP2015552798A JP2015552798A JP2016513075A5 JP 2016513075 A5 JP2016513075 A5 JP 2016513075A5 JP 2015552798 A JP2015552798 A JP 2015552798A JP 2015552798 A JP2015552798 A JP 2015552798A JP 2016513075 A5 JP2016513075 A5 JP 2016513075A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- composition according
- individual
- nucleoside
- nucleoside transporter
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 claims description 37
- 108091006527 nucleoside transporters Proteins 0.000 claims description 27
- 102000019055 Nucleoside Transport Proteins Human genes 0.000 claims description 26
- 108010088751 Albumins Proteins 0.000 claims description 13
- 102000009027 Albumins Human genes 0.000 claims description 13
- 229940123237 Taxane Drugs 0.000 claims description 13
- 239000002105 nanoparticle Substances 0.000 claims description 13
- DKPFODGZWDEEBT-QFIAKTPHSA-N taxane Chemical class C([C@]1(C)CCC[C@@H](C)[C@H]1C1)C[C@H]2[C@H](C)CC[C@@H]1C2(C)C DKPFODGZWDEEBT-QFIAKTPHSA-N 0.000 claims description 13
- 229930012538 Paclitaxel Natural products 0.000 claims description 6
- 229960001592 paclitaxel Drugs 0.000 claims description 6
- RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 claims description 6
- 239000003795 chemical substances by application Substances 0.000 claims description 4
- 239000002777 nucleoside Substances 0.000 claims description 4
- 150000003833 nucleoside derivatives Chemical class 0.000 claims description 4
- 238000012151 immunohistochemical method Methods 0.000 claims description 3
- 102000008100 Human Serum Albumin Human genes 0.000 claims description 2
- 108091006905 Human Serum Albumin Proteins 0.000 claims description 2
- 206010028980 Neoplasm Diseases 0.000 claims description 2
- 201000011510 cancer Diseases 0.000 claims description 2
- SDUQYLNIPVEERB-QPPQHZFASA-N gemcitabine Chemical compound O=C1N=C(N)C=CN1[C@H]1C(F)(F)[C@H](O)[C@@H](CO)O1 SDUQYLNIPVEERB-QPPQHZFASA-N 0.000 claims description 2
- 229960005277 gemcitabine Drugs 0.000 claims description 2
- 108020004999 messenger RNA Proteins 0.000 claims description 2
- 102000004169 proteins and genes Human genes 0.000 claims description 2
- 108090000623 proteins and genes Proteins 0.000 claims description 2
- 229940127073 nucleoside analogue Drugs 0.000 claims 2
- 102000037831 nucleoside transporters Human genes 0.000 claims 1
- 238000000034 method Methods 0.000 description 20
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361848780P | 2013-01-11 | 2013-01-11 | |
| US61/848,780 | 2013-01-11 | ||
| US201361752397P | 2013-01-14 | 2013-01-14 | |
| US61/752,397 | 2013-01-14 | ||
| US13/794,486 | 2013-03-11 | ||
| US13/794,486 US20140199404A1 (en) | 2013-01-11 | 2013-03-11 | Method for treating cancer based on level of a nucleoside transporter |
| PCT/US2014/011006 WO2014110345A1 (en) | 2013-01-11 | 2014-01-10 | Method for treating cancer based on level of a nucleoside transporter |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016513075A JP2016513075A (ja) | 2016-05-12 |
| JP2016513075A5 true JP2016513075A5 (Direct) | 2017-02-16 |
Family
ID=51165318
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015552798A Pending JP2016513075A (ja) | 2013-01-11 | 2014-01-10 | ヌクレオシド輸送体のレベルに基づくがんの処置方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20140199404A1 (Direct) |
| EP (1) | EP2943191A4 (Direct) |
| JP (1) | JP2016513075A (Direct) |
| CA (1) | CA2897673A1 (Direct) |
| HK (1) | HK1217180A1 (Direct) |
| MX (1) | MX2015008888A (Direct) |
| WO (1) | WO2014110345A1 (Direct) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI1585548T1 (sl) | 2002-12-09 | 2018-11-30 | Abraxis Bioscience, Llc | Sestave in metode odmerjanja farmakoloških sredstev |
| MX383644B (es) | 2005-02-18 | 2025-03-14 | Abraxis Bioscience Llc | Combinaciones y metodos de administracion de agentes terapeuticos y terapia de combinacion. |
| US8735394B2 (en) | 2005-02-18 | 2014-05-27 | Abraxis Bioscience, Llc | Combinations and modes of administration of therapeutic agents and combination therapy |
| BRPI0615265A8 (pt) | 2005-08-31 | 2018-03-06 | Abraxis Bioscience Llc | composições compreendendo agentes farmacêuticos pouco hidrossoluíveis e agentes antimicrobianos |
| EP2117520B1 (en) | 2006-12-14 | 2018-08-29 | Abraxis BioScience, LLC | Breast cancer therapy based on hormone receptor status with nanoparticles comprising taxane |
| DK2155188T3 (da) * | 2007-06-01 | 2013-11-04 | Abraxis Bioscience Llc | Fremgangsmåder og sammensætninger til behandling af tilbagevendende kræft |
| EP3626233A1 (en) | 2009-04-15 | 2020-03-25 | Abraxis BioScience, LLC | Prion-free nanoparticle compositions and methods |
| ES2580135T3 (es) | 2010-03-26 | 2016-08-19 | Abraxis Bioscience, Llc | Métodos de tratamiento de carcinoma hepatocelular |
| KR101894689B1 (ko) | 2010-03-29 | 2018-09-04 | 아브락시스 바이오사이언스, 엘엘씨 | 암의 치료 방법 |
| KR20180050426A (ko) | 2010-03-29 | 2018-05-14 | 아브락시스 바이오사이언스, 엘엘씨 | 치료제의 약물 전달 및 유효성 향상 방법 |
| CA2801645A1 (en) | 2010-06-04 | 2011-12-08 | Abraxis Bioscience, Llc | Use of nanoparticules comprising a taxane and an albumin in the treatment of pancreatic cancer |
| CN103648521A (zh) | 2011-04-28 | 2014-03-19 | 阿布拉科斯生物科学有限公司 | 纳米颗粒组合物的血管内递送及其应用 |
| KR20140107417A (ko) | 2011-12-14 | 2014-09-04 | 아브락시스 바이오사이언스, 엘엘씨 | 입자의 동결건조 또는 동결을 위한 중합체 부형제의 용도 |
| US9149455B2 (en) | 2012-11-09 | 2015-10-06 | Abraxis Bioscience, Llc | Methods of treating melanoma |
| US9511046B2 (en) | 2013-01-11 | 2016-12-06 | Abraxis Bioscience, Llc | Methods of treating pancreatic cancer |
| WO2014159171A1 (en) | 2013-03-12 | 2014-10-02 | Abraxis Bioscience, Llc | Methods of treating lung cancer |
| SG11201507234UA (en) | 2013-03-14 | 2015-10-29 | Abraxis Bioscience Llc | Methods of treating bladder cancer |
| US10527604B1 (en) | 2015-03-05 | 2020-01-07 | Abraxis Bioscience, Llc | Methods of assessing suitability of use of pharmaceutical compositions of albumin and paclitaxel |
| US10705070B1 (en) | 2015-03-05 | 2020-07-07 | Abraxis Bioscience, Llc | Methods of assessing suitability of use of pharmaceutical compositions of albumin and poorly water soluble drug |
| HUE070408T2 (hu) | 2015-06-29 | 2025-06-28 | Abraxis Bioscience Llc | Szirolimuszt és albumint tartalmazó nanorészecskék epitelioid sejtes tumorok kezelésében történõ alkalmazásra |
| WO2017095632A1 (en) * | 2015-11-30 | 2017-06-08 | Mayo Foundation For Medical Education And Research | Heatr1 as a marker for chemoresistance |
| EP3522887A4 (en) * | 2016-10-07 | 2020-06-10 | Abraxis BioScience, LLC | METHODS OF TREATING BILARIAN CANCER |
| CN111491634A (zh) | 2017-07-31 | 2020-08-04 | 詹纽瑞治疗公司 | 有机磷酸酯衍生物 |
| AU2019239953B2 (en) | 2018-03-20 | 2025-01-02 | Abraxis Bioscience, Llc | Methods of treating central nervous system disorders via administration of nanoparticles of an mtor inhibitor and an albumin |
| US11708637B2 (en) * | 2019-08-13 | 2023-07-25 | The Regents Of The University Of California | Methods of supporting a graphene sheet disposed on a frame support |
| KR20220106758A (ko) | 2019-10-28 | 2022-07-29 | 아브락시스 바이오사이언스, 엘엘씨 | 알부민 및 라파마이신의 제약 조성물 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA200204907B (en) * | 2001-06-26 | 2003-03-03 | Univ Nat Taiwan | Collapsin Response Mediator Protein-1. |
| MX383644B (es) * | 2005-02-18 | 2025-03-14 | Abraxis Bioscience Llc | Combinaciones y metodos de administracion de agentes terapeuticos y terapia de combinacion. |
| KR20180050426A (ko) * | 2010-03-29 | 2018-05-14 | 아브락시스 바이오사이언스, 엘엘씨 | 치료제의 약물 전달 및 유효성 향상 방법 |
| WO2011121453A2 (en) * | 2010-03-30 | 2011-10-06 | Clavis Pharma Asa | Methods and compositions for treating or ameliorating cancer using gemcitabine-5'-elaidate |
| ES2639038T3 (es) * | 2010-06-02 | 2017-10-25 | Abraxis Bioscience, Llc | Métodos para el tratamiento de cáncer de vejiga |
| EP2739290A4 (en) * | 2011-08-02 | 2015-04-15 | Clovis Oncology Inc | METHOD FOR SELECTION OF CHEMOTHERAPEUTICS AGAINST ADENOCARCINOMAS |
-
2013
- 2013-03-11 US US13/794,486 patent/US20140199404A1/en not_active Abandoned
-
2014
- 2014-01-10 MX MX2015008888A patent/MX2015008888A/es unknown
- 2014-01-10 EP EP14737533.1A patent/EP2943191A4/en not_active Withdrawn
- 2014-01-10 JP JP2015552798A patent/JP2016513075A/ja active Pending
- 2014-01-10 HK HK16105218.7A patent/HK1217180A1/zh unknown
- 2014-01-10 WO PCT/US2014/011006 patent/WO2014110345A1/en not_active Ceased
- 2014-01-10 CA CA2897673A patent/CA2897673A1/en not_active Abandoned
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