JP2016506387A5 - - Google Patents
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- Publication number
- JP2016506387A5 JP2016506387A5 JP2015545840A JP2015545840A JP2016506387A5 JP 2016506387 A5 JP2016506387 A5 JP 2016506387A5 JP 2015545840 A JP2015545840 A JP 2015545840A JP 2015545840 A JP2015545840 A JP 2015545840A JP 2016506387 A5 JP2016506387 A5 JP 2016506387A5
- Authority
- JP
- Japan
- Prior art keywords
- phenyl
- optionally substituted
- carboxylic acid
- amide
- dioxin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 CC*c1cc(*)c(*)c(*)c1* Chemical compound CC*c1cc(*)c(*)c(*)c1* 0.000 description 3
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261734184P | 2012-12-06 | 2012-12-06 | |
| US61/734,184 | 2012-12-06 | ||
| PCT/US2013/073319 WO2014089296A2 (en) | 2012-12-06 | 2013-12-05 | Functionalized benzamide derivatives as antiviral agents against hbv infection |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018109976A Division JP2018162272A (ja) | 2012-12-06 | 2018-06-08 | Ｈｂｖ感染に対する抗ウイルス剤としての官能化ベンズアミド誘導体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016506387A JP2016506387A (ja) | 2016-03-03 |
| JP2016506387A5 true JP2016506387A5 (OSRAM) | 2016-07-21 |
| JP6353460B2 JP6353460B2 (ja) | 2018-07-04 |
Family
ID=50884140
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015545840A Expired - Fee Related JP6353460B2 (ja) | 2012-12-06 | 2013-12-05 | Ｈｂｖ感染に対する抗ウイルス剤としての官能化ベンズアミド誘導体 |
| JP2018109976A Pending JP2018162272A (ja) | 2012-12-06 | 2018-06-08 | Ｈｂｖ感染に対する抗ウイルス剤としての官能化ベンズアミド誘導体 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018109976A Pending JP2018162272A (ja) | 2012-12-06 | 2018-06-08 | Ｈｂｖ感染に対する抗ウイルス剤としての官能化ベンズアミド誘導体 |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US20150307443A1 (OSRAM) |
| EP (1) | EP2928459A4 (OSRAM) |
| JP (2) | JP6353460B2 (OSRAM) |
| KR (1) | KR20150090219A (OSRAM) |
| CN (2) | CN104918612B (OSRAM) |
| AU (2) | AU2013355220B2 (OSRAM) |
| BR (1) | BR112015013121A2 (OSRAM) |
| CA (1) | CA2892606A1 (OSRAM) |
| IL (1) | IL238930B (OSRAM) |
| NZ (2) | NZ748966A (OSRAM) |
| PH (1) | PH12015501276A1 (OSRAM) |
| SG (2) | SG10201900695PA (OSRAM) |
| WO (1) | WO2014089296A2 (OSRAM) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9938236B2 (en) | 2012-12-27 | 2018-04-10 | Drexel University | Antiviral agents against HBV infection |
| PH12016501762B1 (en) | 2014-03-13 | 2023-01-11 | Assembly Biosciences Inc | Hepatitis b core protein allosteric modulators |
| WO2016177655A1 (en) * | 2015-05-04 | 2016-11-10 | F. Hoffmann-La Roche Ag | Tetrahydropyridopyrimidines and tetrahydropyridopyridines as inhibitors of hbsag (hbv surface antigen) and hbv dna production for the treatment of hepatitis b virus infections |
| TW201720802A (zh) | 2015-09-15 | 2017-06-16 | 艾森伯利生物科學公司 | B型肝炎核心蛋白質調節劑 |
| EP4653462A2 (en) | 2016-08-22 | 2025-11-26 | Arbutus Biopharma Corporation | Anti-pd-1 antibodies, or fragments thereof, for treating hepatitis b |
| JOP20190024A1 (ar) | 2016-08-26 | 2019-02-19 | Gilead Sciences Inc | مركبات بيروليزين بها استبدال واستخداماتها |
| US11001564B2 (en) | 2016-09-13 | 2021-05-11 | Arbutus Biopharma Corporation | Substituted chromane-8-carboxamide compounds and analogues thereof, and methods using same |
| CA3037151A1 (en) | 2016-09-15 | 2018-03-22 | Assembly Biosciences, Inc. | Hepatitis b core protein modulators |
| CN116751200A (zh) | 2016-11-07 | 2023-09-15 | 爱彼特生物制药公司 | 含有取代的吡啶酮的三环化合物以及使用其的方法 |
| JP2020511436A (ja) | 2017-03-02 | 2020-04-16 | アッセンブリー バイオサイエンシズ，インコーポレイテッド | 環状スルファミド化合物およびその使用方法 |
| EP3601216B1 (en) | 2017-03-21 | 2023-10-25 | Arbutus Biopharma Corporation | Substituted dihydroindene-4-carboxamides and analogs thereof, and methods using same for the treatment of hepatitis b virus infection |
| CA3091142C (en) | 2018-02-26 | 2023-04-11 | Gilead Sciences, Inc. | Substituted pyrrolizine compounds and uses thereof |
| CN109627182B (zh) * | 2018-06-13 | 2021-04-02 | 浙江大学 | 一种羟苯水杨胺羟基化物、制备方法及其应用 |
| TWI826492B (zh) | 2018-07-27 | 2023-12-21 | 加拿大商愛彼特生物製藥公司 | 經取代四氫環戊[c]吡咯、經取代二氫吡咯，其類似物及使用其之方法 |
| KR20210095143A (ko) | 2018-10-22 | 2021-07-30 | 어셈블리 바이오사이언시스, 인크. | Hbv의 치료를 위한 5원 헤테로아릴 카르복스아미드 화합물 |
| US20210395751A1 (en) | 2018-10-31 | 2021-12-23 | The University Of Sydney | Compositions and methods for treating viral infections |
| TWI827760B (zh) | 2018-12-12 | 2024-01-01 | 加拿大商愛彼特生物製藥公司 | 經取代之芳基甲基脲類及雜芳基甲基脲類、其類似物及其使用方法 |
| EP3975996A1 (en) | 2019-05-24 | 2022-04-06 | Assembly Biosciences, Inc. | Pharmaceutical compositions for the treatment of hbv |
| EP4077473A4 (en) | 2019-12-20 | 2024-05-01 | Arbutus Biopharma Corporation | SYNTHETIC PROCESSES AND INTERMEDIATE PRODUCTS |
| WO2021216661A1 (en) | 2020-04-22 | 2021-10-28 | Assembly Biosciences, Inc. | Pyrazole carboxamide compounds for treatment of hbv |
| WO2021216642A1 (en) | 2020-04-22 | 2021-10-28 | Assembly Biosciences, Inc. | Pyrazole carboxamide compounds for treatment of hbv |
| EP4139292A1 (en) | 2020-04-22 | 2023-03-01 | Assembly Biosciences, Inc. | 5-membered heteroaryl carboxamide compounds for treatment of hbv |
| WO2021216660A1 (en) | 2020-04-22 | 2021-10-28 | Assembly Biosciences, Inc. | 5-membered heteroaryl carboxamide compounds for treatment of hbv |
| US20210371388A1 (en) * | 2020-05-12 | 2021-12-02 | Baruch S. Blumberg Institute | Bicyclic Carboxamide with Exocyclic Urea Derivatives as Antivirals for the Treatment of HBV Infection |
| TW202214574A (zh) * | 2020-06-08 | 2022-04-16 | 加拿大商愛彼特生物製藥公司 | 經取代之(呔-1-基甲基)脲類、經取代之n-(呔-1-基甲基)醯胺類及其類似物 |
| WO2023069547A1 (en) | 2021-10-20 | 2023-04-27 | Assembly Biosciences, Inc. | 5-membered heteroaryl carboxamide compounds for treatment of hbv |
| WO2023069545A1 (en) | 2021-10-20 | 2023-04-27 | Assembly Biosciences, Inc. | 5-membered heteroaryl carboxamide compounds for treatment of hbv |
| WO2023069544A1 (en) | 2021-10-20 | 2023-04-27 | Assembly Biosciences, Inc. | 5-membered heteroaryl carboxamide compounds for treatment of hbv |
| WO2023164179A1 (en) | 2022-02-25 | 2023-08-31 | Assembly Biosciences, Inc. | Benzothia(dia)zepine compounds for treatment of hbv and hdv |
| WO2023164186A1 (en) | 2022-02-25 | 2023-08-31 | Assembly Biosciences, Inc. | Benzothia(dia)zepine compounds for treatment of hbv and hdv |
| WO2023164183A1 (en) | 2022-02-25 | 2023-08-31 | Assembly Biosciences, Inc. | Benzothia(dia)zepine compounds for treatment of hbv and hdv |
| WO2023164181A1 (en) | 2022-02-25 | 2023-08-31 | Assembly Biosciences, Inc. | Benzothia(dia)zepine compounds for treatment of hbv and hdv |
| EP4635523A1 (en) | 2022-12-14 | 2025-10-22 | Maruemu Works Co., Ltd. | Base material for screw, screw, and method for producing same |
| WO2025043094A1 (en) | 2023-08-23 | 2025-02-27 | Assembly Biosciences, Inc. | Benzothia(dia)zepine compounds for treatment of hbv and hdv |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL108459A0 (en) * | 1993-02-05 | 1994-04-12 | Opjohn Company | 4-Hydroxy-benzopyran-2-ones and 4-hydroxy-cycloalkyl [B] pyran-2-ones useful for treating infections due to hiv and other retroviruses |
| JPH06297860A (ja) * | 1993-04-14 | 1994-10-25 | New Oji Paper Co Ltd | 感熱記録体 |
| AU9318298A (en) * | 1997-11-14 | 1999-06-07 | Warner-Lambert Company | Small molecule intervention in hiv-1 replication |
| HUP0100860A3 (en) * | 1997-12-11 | 2003-03-28 | Janssen Pharmaceutica Nv | Retinoic acid mimetic anilides, process for their preparation and pharmaceutical compositions containing them |
| US6653309B1 (en) * | 1999-04-26 | 2003-11-25 | Vertex Pharmaceuticals Incorporated | Inhibitors of IMPDH enzyme technical field of the invention |
| AU2001269092A1 (en) * | 2000-06-27 | 2002-01-08 | Axxima Pharmaceuticals Ag | Inhibitors of hepatitis b virus infection |
| DE10109856A1 (de) * | 2001-03-01 | 2002-09-05 | Bayer Ag | Arzneimittel gegen virale Erkrankungen |
| KR100863667B1 (ko) * | 2002-09-11 | 2008-10-15 | 가부시끼가이샤 구레하 | 아민 화합물 및 그 용도 |
| WO2004110352A2 (en) * | 2003-05-16 | 2004-12-23 | The Regents Of The University Of California | Compounds having activity in increasing ion transport by mutant-cftr and uses thereof |
| SE0401342D0 (sv) * | 2004-05-25 | 2004-05-25 | Astrazeneca Ab | Therapeutic compounds |
| US20070161648A1 (en) * | 2005-10-14 | 2007-07-12 | Hughes Terry V | Substituted dihydro-isoindolones useful in treating kinase disorders |
| CN1951932B (zh) * | 2005-10-20 | 2010-11-24 | 北京科莱博医药开发有限责任公司 | [n-(3',4'亚甲二氧基)苯基乙基]甲酰胺基苯甲酸衍生物,它们的制备方法及其用途 |
| KR101391900B1 (ko) * | 2005-12-13 | 2014-05-02 | 인사이트 코포레이션 | 야누스 키나아제 억제제로서의 헤테로아릴 치환된 피롤로［2,3-ｂ］피리딘 및 피롤로［2,3-ｂ］피리미딘 |
| WO2007143557A2 (en) * | 2006-06-02 | 2007-12-13 | Brandeis University | Compounds and methods for treating mammalian gastrointestinal parasitic infections |
| DE102006060598A1 (de) * | 2006-12-21 | 2008-06-26 | Merck Patent Gmbh | Tetrahydrobenzoisoxazole |
| KR101561292B1 (ko) * | 2007-04-09 | 2015-10-19 | 메틸진 인코포레이티드 | 히스톤 탈아세틸화효소의 억제제 |
| US8309340B2 (en) * | 2007-12-27 | 2012-11-13 | Hoffmann-La Roche Inc. | Insulin degrading enzyme crystals |
| CN104163816A (zh) * | 2008-12-03 | 2014-11-26 | 普雷西迪奥制药公司 | Hcv ns5a的抑制剂 |
| EP2377850A1 (en) * | 2010-03-30 | 2011-10-19 | Pharmeste S.r.l. | TRPV1 vanilloid receptor antagonists with a bicyclic portion |
| WO2012058378A1 (en) * | 2010-10-29 | 2012-05-03 | Romark Laboratories L.C. | Pharmaceutical compositions and methods of use of salicylanilides for treatment of hepatitis viruses |
| WO2012126881A1 (en) * | 2011-03-22 | 2012-09-27 | Syngenta Participations Ag | Insecticidal compounds |
| WO2012135697A2 (en) * | 2011-03-30 | 2012-10-04 | H. Lee Moffitt Cancer Center & Research Institute Inc. | Novel rho kinase inhibitors and methods of use |
-
2013
- 2013-12-05 KR KR1020157017223A patent/KR20150090219A/ko not_active Ceased
- 2013-12-05 WO PCT/US2013/073319 patent/WO2014089296A2/en not_active Ceased
- 2013-12-05 SG SG10201900695PA patent/SG10201900695PA/en unknown
- 2013-12-05 CN CN201380065824.0A patent/CN104918612B/zh not_active Expired - Fee Related
- 2013-12-05 US US14/650,159 patent/US20150307443A1/en not_active Abandoned
- 2013-12-05 BR BR112015013121A patent/BR112015013121A2/pt not_active IP Right Cessation
- 2013-12-05 JP JP2015545840A patent/JP6353460B2/ja not_active Expired - Fee Related
- 2013-12-05 CA CA2892606A patent/CA2892606A1/en not_active Abandoned
- 2013-12-05 CN CN201910903071.5A patent/CN110642741A/zh active Pending
- 2013-12-05 AU AU2013355220A patent/AU2013355220B2/en not_active Ceased
- 2013-12-05 NZ NZ748966A patent/NZ748966A/en not_active IP Right Cessation
- 2013-12-05 SG SG11201503997VA patent/SG11201503997VA/en unknown
- 2013-12-05 NZ NZ708392A patent/NZ708392A/en not_active IP Right Cessation
- 2013-12-05 EP EP13859675.4A patent/EP2928459A4/en not_active Withdrawn
-
2015
- 2015-05-20 IL IL238930A patent/IL238930B/en not_active IP Right Cessation
- 2015-06-05 PH PH12015501276A patent/PH12015501276A1/en unknown
-
2018
- 2018-06-08 JP JP2018109976A patent/JP2018162272A/ja active Pending
- 2018-11-01 AU AU2018256602A patent/AU2018256602A1/en not_active Abandoned
- 2018-11-28 US US16/202,822 patent/US20190092720A1/en not_active Abandoned
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