JP2016506387A5 - - Google Patents
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- Publication number
- JP2016506387A5 JP2016506387A5 JP2015545840A JP2015545840A JP2016506387A5 JP 2016506387 A5 JP2016506387 A5 JP 2016506387A5 JP 2015545840 A JP2015545840 A JP 2015545840A JP 2015545840 A JP2015545840 A JP 2015545840A JP 2016506387 A5 JP2016506387 A5 JP 2016506387A5
- Authority
- JP
- Japan
- Prior art keywords
- phenyl
- optionally substituted
- carboxylic acid
- amide
- dioxin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 CC*c1cc(*)c(*)c(*)c1* Chemical compound CC*c1cc(*)c(*)c(*)c1* 0.000 description 3
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261734184P | 2012-12-06 | 2012-12-06 | |
| US61/734,184 | 2012-12-06 | ||
| PCT/US2013/073319 WO2014089296A2 (en) | 2012-12-06 | 2013-12-05 | Functionalized benzamide derivatives as antiviral agents against hbv infection |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018109976A Division JP2018162272A (ja) | 2012-12-06 | 2018-06-08 | Ｈｂｖ感染に対する抗ウイルス剤としての官能化ベンズアミド誘導体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016506387A JP2016506387A (ja) | 2016-03-03 |
| JP2016506387A5 true JP2016506387A5 (OSRAM) | 2016-07-21 |
| JP6353460B2 JP6353460B2 (ja) | 2018-07-04 |
Family
ID=50884140
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015545840A Expired - Fee Related JP6353460B2 (ja) | 2012-12-06 | 2013-12-05 | Ｈｂｖ感染に対する抗ウイルス剤としての官能化ベンズアミド誘導体 |
| JP2018109976A Pending JP2018162272A (ja) | 2012-12-06 | 2018-06-08 | Ｈｂｖ感染に対する抗ウイルス剤としての官能化ベンズアミド誘導体 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018109976A Pending JP2018162272A (ja) | 2012-12-06 | 2018-06-08 | Ｈｂｖ感染に対する抗ウイルス剤としての官能化ベンズアミド誘導体 |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US20150307443A1 (OSRAM) |
| EP (1) | EP2928459A4 (OSRAM) |
| JP (2) | JP6353460B2 (OSRAM) |
| KR (1) | KR20150090219A (OSRAM) |
| CN (2) | CN110642741A (OSRAM) |
| AU (2) | AU2013355220B2 (OSRAM) |
| BR (1) | BR112015013121A2 (OSRAM) |
| CA (1) | CA2892606A1 (OSRAM) |
| IL (1) | IL238930B (OSRAM) |
| NZ (2) | NZ708392A (OSRAM) |
| PH (1) | PH12015501276A1 (OSRAM) |
| SG (2) | SG11201503997VA (OSRAM) |
| WO (1) | WO2014089296A2 (OSRAM) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HK1217649A1 (zh) * | 2012-12-27 | 2017-01-20 | 德雷克塞尔大学 | 針對hbv感染的新型抗病毒劑 |
| ES2748029T3 (es) | 2014-03-13 | 2020-03-12 | Univ Indiana Res & Tech Corp | Moduladores alostéricos de proteína núcleo de hepatitis B |
| CN107624113B (zh) * | 2015-05-04 | 2020-10-23 | 豪夫迈·罗氏有限公司 | 作为HBsAg (HBV 表面抗原)和HBV DNA 生成的抑制剂用于治疗乙型肝炎病毒感染的四氢吡啶并嘧啶和四氢吡啶并吡啶类化合物 |
| TWI786639B (zh) | 2015-09-15 | 2022-12-11 | 美商艾森伯利生物科學公司 | B型肝炎核心蛋白質調節劑 |
| US20210284733A1 (en) | 2016-08-22 | 2021-09-16 | Arbutus Biopharma Corporation | Anti-pd-1 antibodies, or fragments thereof, for treating hepatitis b |
| JOP20190024A1 (ar) | 2016-08-26 | 2019-02-19 | Gilead Sciences Inc | مركبات بيروليزين بها استبدال واستخداماتها |
| WO2018052967A1 (en) * | 2016-09-13 | 2018-03-22 | Arbutus Biopharma, Inc. | Substituted chromane-8-carboxamide compounds and analogues thereof, and methods using same |
| CA3037151A1 (en) | 2016-09-15 | 2018-03-22 | Assembly Biosciences, Inc. | Hepatitis b core protein modulators |
| SG11201902944TA (en) | 2016-11-07 | 2019-05-30 | Arbutus Biopharma Corp | Substituted pyridinone-containing tricyclic compounds, and methods using same |
| SG11201908012SA (en) | 2017-03-02 | 2019-09-27 | Assembly Biosciences Inc | Cyclic sulfamide compounds and methods of using same |
| CA3056886A1 (en) | 2017-03-21 | 2018-09-27 | Arbutus Biopharma Corporation | Substituted dihydroindene-4-carboxamides and analogs thereof, and methods using same |
| US10836769B2 (en) | 2018-02-26 | 2020-11-17 | Gilead Sciences, Inc. | Substituted pyrrolizine compounds and uses thereof |
| CN112724037B (zh) * | 2018-06-13 | 2022-03-11 | 浙江大学 | 一种羟苯水杨胺羟基化物、制备方法及其应用 |
| TWI826492B (zh) | 2018-07-27 | 2023-12-21 | 加拿大商愛彼特生物製藥公司 | 經取代四氫環戊[c]吡咯、經取代二氫吡咯，其類似物及使用其之方法 |
| CN113195055A (zh) | 2018-10-22 | 2021-07-30 | 组装生物科学股份有限公司 | 用于hbv治疗的5元杂芳基甲酰胺化合物 |
| ES3023937T3 (en) | 2018-10-31 | 2025-06-03 | The Westmead Institute For Medical Res | Pharmaceutical compositions for use in treating an hbv or hdv infection |
| TWI827760B (zh) | 2018-12-12 | 2024-01-01 | 加拿大商愛彼特生物製藥公司 | 經取代之芳基甲基脲類及雜芳基甲基脲類、其類似物及其使用方法 |
| BR112021023622A2 (pt) | 2019-05-24 | 2022-04-19 | Assembly Biosciences Inc | Composições farmaceuticas para o tratamento de hbv |
| IL294064A (en) | 2019-12-20 | 2022-08-01 | Arbutus Biopharma Corp | Artificial processes and intermediates |
| BR112022021419A2 (pt) | 2020-04-22 | 2023-03-07 | Assembly Biosciences Inc | Compostos de heteroaril carboxamida de 5 membros para o tratamento de hbv |
| WO2021216661A1 (en) | 2020-04-22 | 2021-10-28 | Assembly Biosciences, Inc. | Pyrazole carboxamide compounds for treatment of hbv |
| EP4139000A1 (en) | 2020-04-22 | 2023-03-01 | Assembly Biosciences, Inc. | Pyrazole carboxamide compounds for treatment of hbv |
| WO2021216660A1 (en) | 2020-04-22 | 2021-10-28 | Assembly Biosciences, Inc. | 5-membered heteroaryl carboxamide compounds for treatment of hbv |
| US20210371388A1 (en) * | 2020-05-12 | 2021-12-02 | Baruch S. Blumberg Institute | Bicyclic Carboxamide with Exocyclic Urea Derivatives as Antivirals for the Treatment of HBV Infection |
| TW202214574A (zh) * | 2020-06-08 | 2022-04-16 | 加拿大商愛彼特生物製藥公司 | 經取代之(呔-1-基甲基)脲類、經取代之n-(呔-1-基甲基)醯胺類及其類似物 |
| WO2023069545A1 (en) | 2021-10-20 | 2023-04-27 | Assembly Biosciences, Inc. | 5-membered heteroaryl carboxamide compounds for treatment of hbv |
| WO2023069547A1 (en) | 2021-10-20 | 2023-04-27 | Assembly Biosciences, Inc. | 5-membered heteroaryl carboxamide compounds for treatment of hbv |
| WO2023069544A1 (en) | 2021-10-20 | 2023-04-27 | Assembly Biosciences, Inc. | 5-membered heteroaryl carboxamide compounds for treatment of hbv |
| WO2023164179A1 (en) | 2022-02-25 | 2023-08-31 | Assembly Biosciences, Inc. | Benzothia(dia)zepine compounds for treatment of hbv and hdv |
| WO2023164181A1 (en) | 2022-02-25 | 2023-08-31 | Assembly Biosciences, Inc. | Benzothia(dia)zepine compounds for treatment of hbv and hdv |
| WO2023164183A1 (en) | 2022-02-25 | 2023-08-31 | Assembly Biosciences, Inc. | Benzothia(dia)zepine compounds for treatment of hbv and hdv |
| WO2023164186A1 (en) | 2022-02-25 | 2023-08-31 | Assembly Biosciences, Inc. | Benzothia(dia)zepine compounds for treatment of hbv and hdv |
| JPWO2024128244A1 (OSRAM) | 2022-12-14 | 2024-06-20 | ||
| WO2025043094A1 (en) | 2023-08-23 | 2025-02-27 | Assembly Biosciences, Inc. | Benzothia(dia)zepine compounds for treatment of hbv and hdv |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL108459A0 (en) * | 1993-02-05 | 1994-04-12 | Opjohn Company | 4-Hydroxy-benzopyran-2-ones and 4-hydroxy-cycloalkyl [B] pyran-2-ones useful for treating infections due to hiv and other retroviruses |
| JPH06297860A (ja) * | 1993-04-14 | 1994-10-25 | New Oji Paper Co Ltd | 感熱記録体 |
| WO1999025327A2 (en) * | 1997-11-14 | 1999-05-27 | Warner-Lambert Company | Small molecule intervention in hiv-1 replication |
| DE69824885T2 (de) * | 1997-12-11 | 2005-07-21 | Janssen Pharmaceutica N.V. | Anilide als vitamin-a-säure-mimetika |
| US6653309B1 (en) * | 1999-04-26 | 2003-11-25 | Vertex Pharmaceuticals Incorporated | Inhibitors of IMPDH enzyme technical field of the invention |
| AU2001269092A1 (en) * | 2000-06-27 | 2002-01-08 | Axxima Pharmaceuticals Ag | Inhibitors of hepatitis b virus infection |
| DE10109856A1 (de) * | 2001-03-01 | 2002-09-05 | Bayer Ag | Arzneimittel gegen virale Erkrankungen |
| US7176227B2 (en) * | 2002-09-11 | 2007-02-13 | Kureha Corporation | Amine compounds and use thereof |
| WO2004110352A2 (en) * | 2003-05-16 | 2004-12-23 | The Regents Of The University Of California | Compounds having activity in increasing ion transport by mutant-cftr and uses thereof |
| SE0401342D0 (sv) * | 2004-05-25 | 2004-05-25 | Astrazeneca Ab | Therapeutic compounds |
| WO2007047646A2 (en) * | 2005-10-14 | 2007-04-26 | Janssen Pharmaceutica, N.V. | Substituted dihydro-isoindolones useful in treating kinase disorders |
| CN1951932B (zh) * | 2005-10-20 | 2010-11-24 | 北京科莱博医药开发有限责任公司 | [n-(3',4'亚甲二氧基)苯基乙基]甲酰胺基苯甲酸衍生物,它们的制备方法及其用途 |
| EP2343298B9 (en) * | 2005-12-13 | 2020-05-06 | Incyte Holdings Corporation | Heteroaryl substituted pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrimidines as Janus kinase inhibitors |
| WO2007143557A2 (en) * | 2006-06-02 | 2007-12-13 | Brandeis University | Compounds and methods for treating mammalian gastrointestinal parasitic infections |
| DE102006060598A1 (de) * | 2006-12-21 | 2008-06-26 | Merck Patent Gmbh | Tetrahydrobenzoisoxazole |
| EP2139850B1 (en) * | 2007-04-09 | 2018-09-12 | MethylGene Inc. | Inhibitors of histone deacetylase |
| JP2011507537A (ja) * | 2007-12-27 | 2011-03-10 | エフ．ホフマン−ラ ロシュ アーゲー | インシュリン分解酵素結晶 |
| EP2682393A1 (en) * | 2008-12-03 | 2014-01-08 | Presidio Pharmaceuticals, Inc. | Inhibitors of HCV NS5A comprising a bicyclic core. |
| EP2377850A1 (en) * | 2010-03-30 | 2011-10-19 | Pharmeste S.r.l. | TRPV1 vanilloid receptor antagonists with a bicyclic portion |
| WO2012058378A1 (en) * | 2010-10-29 | 2012-05-03 | Romark Laboratories L.C. | Pharmaceutical compositions and methods of use of salicylanilides for treatment of hepatitis viruses |
| WO2012126881A1 (en) * | 2011-03-22 | 2012-09-27 | Syngenta Participations Ag | Insecticidal compounds |
| WO2012135697A2 (en) * | 2011-03-30 | 2012-10-04 | H. Lee Moffitt Cancer Center & Research Institute Inc. | Novel rho kinase inhibitors and methods of use |
-
2013
- 2013-12-05 EP EP13859675.4A patent/EP2928459A4/en not_active Withdrawn
- 2013-12-05 CN CN201910903071.5A patent/CN110642741A/zh active Pending
- 2013-12-05 NZ NZ708392A patent/NZ708392A/en not_active IP Right Cessation
- 2013-12-05 CN CN201380065824.0A patent/CN104918612B/zh not_active Expired - Fee Related
- 2013-12-05 KR KR1020157017223A patent/KR20150090219A/ko not_active Ceased
- 2013-12-05 BR BR112015013121A patent/BR112015013121A2/pt not_active IP Right Cessation
- 2013-12-05 JP JP2015545840A patent/JP6353460B2/ja not_active Expired - Fee Related
- 2013-12-05 CA CA2892606A patent/CA2892606A1/en not_active Abandoned
- 2013-12-05 SG SG11201503997VA patent/SG11201503997VA/en unknown
- 2013-12-05 SG SG10201900695PA patent/SG10201900695PA/en unknown
- 2013-12-05 NZ NZ748966A patent/NZ748966A/en not_active IP Right Cessation
- 2013-12-05 WO PCT/US2013/073319 patent/WO2014089296A2/en not_active Ceased
- 2013-12-05 AU AU2013355220A patent/AU2013355220B2/en not_active Ceased
- 2013-12-05 US US14/650,159 patent/US20150307443A1/en not_active Abandoned
-
2015
- 2015-05-20 IL IL238930A patent/IL238930B/en not_active IP Right Cessation
- 2015-06-05 PH PH12015501276A patent/PH12015501276A1/en unknown
-
2018
- 2018-06-08 JP JP2018109976A patent/JP2018162272A/ja active Pending
- 2018-11-01 AU AU2018256602A patent/AU2018256602A1/en not_active Abandoned
- 2018-11-28 US US16/202,822 patent/US20190092720A1/en not_active Abandoned
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