JP2016501844A5 - - Google Patents
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- Publication number
- JP2016501844A5 JP2016501844A5 JP2015540743A JP2015540743A JP2016501844A5 JP 2016501844 A5 JP2016501844 A5 JP 2016501844A5 JP 2015540743 A JP2015540743 A JP 2015540743A JP 2015540743 A JP2015540743 A JP 2015540743A JP 2016501844 A5 JP2016501844 A5 JP 2016501844A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutically acceptable
- compound according
- acceptable salt
- compound
- phenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 150000001875 compounds Chemical class 0.000 claims 9
- 150000003839 salts Chemical class 0.000 claims 6
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 2
- 125000001559 cyclopropyl group Chemical group [H]C1([H])C([H])([H])C1([H])* 0.000 claims 1
- 239000003085 diluting agent Substances 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 229910052736 halogen Inorganic materials 0.000 claims 1
- 150000002367 halogens Chemical class 0.000 claims 1
- 208000006575 hypertriglyceridemia Diseases 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
- 0 C[C@](*1)(SC)[U]CCCc2c1cc(*)cc2 Chemical compound C[C@](*1)(SC)[U]CCCc2c1cc(*)cc2 0.000 description 5
- MEFBFOAEVCSUND-UHFFFAOYSA-N C[I](C)[N-](CCc1ccccc11)C1=O Chemical compound C[I](C)[N-](CCc1ccccc11)C1=O MEFBFOAEVCSUND-UHFFFAOYSA-N 0.000 description 1
- NUBQPEPTQRWIPT-UHFFFAOYSA-N O=C1OC2C=CC=CC2NC1 Chemical compound O=C1OC2C=CC=CC2NC1 NUBQPEPTQRWIPT-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12382431 | 2012-11-06 | ||
| EP12382431.0 | 2012-11-06 | ||
| US201361748935P | 2013-01-04 | 2013-01-04 | |
| US61/748,935 | 2013-01-04 | ||
| PCT/US2013/067466 WO2014074365A1 (en) | 2012-11-06 | 2013-10-30 | Novel benzyl sulfonamide compounds useful as mogat-2 inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016501844A JP2016501844A (ja) | 2016-01-21 |
| JP2016501844A5 true JP2016501844A5 (cg-RX-API-DMAC7.html) | 2016-11-24 |
Family
ID=47143796
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015540743A Ceased JP2016501844A (ja) | 2012-11-06 | 2013-10-30 | ＭｏＧＡＴ−２阻害剤として有用な新規のベンジルスルホンアミド化合物 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US9416138B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2917194B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2016501844A (cg-RX-API-DMAC7.html) |
| KR (1) | KR20150063519A (cg-RX-API-DMAC7.html) |
| CN (1) | CN104768941B (cg-RX-API-DMAC7.html) |
| AU (1) | AU2013341584A1 (cg-RX-API-DMAC7.html) |
| BR (1) | BR112015009567A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2886831A1 (cg-RX-API-DMAC7.html) |
| EA (1) | EA201590696A1 (cg-RX-API-DMAC7.html) |
| MX (1) | MX2015005739A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2014074365A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2807147A1 (en) | 2012-01-23 | 2014-12-03 | Eli Lilly and Company | Phenyl methanesulfonamide derivatives useful as mgat - 2 inhibitors |
| CA2859992A1 (en) | 2012-01-31 | 2013-08-08 | Eli Lilly And Company | Novel morpholinyl derivatives useful as mogat-2 inhibitors |
| WO2017110841A1 (ja) * | 2015-12-21 | 2017-06-29 | 塩野義製薬株式会社 | Ｍｇａｔ２阻害活性を有する非芳香族複素環誘導体 |
| TWI782056B (zh) | 2017-07-14 | 2022-11-01 | 日商鹽野義製藥股份有限公司 | 具有ｍｇａｔ２抑制活性的縮合環衍生物 |
| EP3909583A4 (en) | 2019-01-11 | 2022-08-17 | Shionogi & Co., Ltd | DIHYDROPYRAZOLOPYRAZINONE DERIVATIVES WITH MGAT2 INHIBITORY ACTIVITY |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0784612A1 (en) * | 1994-10-04 | 1997-07-23 | Fujisawa Pharmaceutical Co., Ltd. | Urea derivatives and their use as acat-inhibitors |
| GB9702194D0 (en) | 1997-02-04 | 1997-03-26 | Lilly Co Eli | Sulphonide derivatives |
| CA2472021C (en) * | 2002-01-29 | 2012-08-14 | Applied Research Systems Ars Holding N.V. | Substituted methylene amide derivatives as modulators of protein tyrosine phosphatases (ptps) |
| NZ550114A (en) * | 2004-04-20 | 2011-02-25 | Transtech Pharma Inc | Substituted thiazole and pyrimidine derivatives as melanocortin receptor modulators |
| EP1655283A1 (en) * | 2004-11-08 | 2006-05-10 | Evotec OAI AG | 11beta-HSD1 Inhibitors |
| EP1659113A1 (en) * | 2004-11-08 | 2006-05-24 | Evotec AG | Inhibitors of 11beta-hydroxy steroid dehydrogenase type 1 (11beta-HSD1) |
| JPWO2008038768A1 (ja) | 2006-09-28 | 2010-01-28 | 大日本住友製薬株式会社 | 二環性ピリミジン構造を有する化合物及びそれを含有する医薬組成物 |
| TW200831092A (en) * | 2006-12-21 | 2008-08-01 | Astrazeneca Ab | Therapeutic agents |
| WO2010095767A1 (en) * | 2009-02-23 | 2010-08-26 | Banyu Pharmaceutical Co.,Ltd. | Pyrimidin-4(3h)-one derivatives |
| CA2757866A1 (en) * | 2009-04-20 | 2010-10-28 | Abbott Laboratories | Novel amide and amidine derivatives and uses thereof |
| US8507493B2 (en) | 2009-04-20 | 2013-08-13 | Abbvie Inc. | Amide and amidine derivatives and uses thereof |
| EP2807147A1 (en) | 2012-01-23 | 2014-12-03 | Eli Lilly and Company | Phenyl methanesulfonamide derivatives useful as mgat - 2 inhibitors |
| CA2859992A1 (en) | 2012-01-31 | 2013-08-08 | Eli Lilly And Company | Novel morpholinyl derivatives useful as mogat-2 inhibitors |
| TW201343629A (zh) | 2012-01-31 | 2013-11-01 | Lilly Co Eli | 可作為ｍｏｇａｔ－２抑制劑之新穎芐磺醯胺衍生物 |
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2013
- 2013-10-30 KR KR1020157011222A patent/KR20150063519A/ko not_active Ceased
- 2013-10-30 CA CA2886831A patent/CA2886831A1/en not_active Abandoned
- 2013-10-30 MX MX2015005739A patent/MX2015005739A/es unknown
- 2013-10-30 US US14/438,435 patent/US9416138B2/en not_active Expired - Fee Related
- 2013-10-30 EA EA201590696A patent/EA201590696A1/ru unknown
- 2013-10-30 EP EP13789443.2A patent/EP2917194B1/en active Active
- 2013-10-30 WO PCT/US2013/067466 patent/WO2014074365A1/en not_active Ceased
- 2013-10-30 AU AU2013341584A patent/AU2013341584A1/en not_active Abandoned
- 2013-10-30 JP JP2015540743A patent/JP2016501844A/ja not_active Ceased
- 2013-10-30 CN CN201380057789.8A patent/CN104768941B/zh not_active Expired - Fee Related
- 2013-10-30 BR BR112015009567A patent/BR112015009567A2/pt not_active IP Right Cessation