JP2016500681A5 - - Google Patents

Download PDF

Info

Publication number
JP2016500681A5
JP2016500681A5 JP2015536990A JP2015536990A JP2016500681A5 JP 2016500681 A5 JP2016500681 A5 JP 2016500681A5 JP 2015536990 A JP2015536990 A JP 2015536990A JP 2015536990 A JP2015536990 A JP 2015536990A JP 2016500681 A5 JP2016500681 A5 JP 2016500681A5
Authority
JP
Japan
Prior art keywords
responsive
polycation
hydrogel
methacrylate
acrylate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
JP2015536990A
Other languages
English (en)
Japanese (ja)
Other versions
JP2016500681A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2013/064887 external-priority patent/WO2014059430A1/en
Publication of JP2016500681A publication Critical patent/JP2016500681A/ja
Publication of JP2016500681A5 publication Critical patent/JP2016500681A5/ja
Ceased legal-status Critical Current

Links

JP2015536990A 2012-10-14 2013-10-14 膜破壊性の応答性ナノスケールヒドロゲルによる低分子干渉rna及びマイクロrnaの送達 Ceased JP2016500681A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261713610P 2012-10-14 2012-10-14
US61/713,610 2012-10-14
PCT/US2013/064887 WO2014059430A1 (en) 2012-10-14 2013-10-14 Delivery of small interfering rna and micro rna through membrane-disruptive, responsive nanoscalle hydrogels

Publications (2)

Publication Number Publication Date
JP2016500681A JP2016500681A (ja) 2016-01-14
JP2016500681A5 true JP2016500681A5 (https=) 2016-12-22

Family

ID=49510546

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2015536990A Ceased JP2016500681A (ja) 2012-10-14 2013-10-14 膜破壊性の応答性ナノスケールヒドロゲルによる低分子干渉rna及びマイクロrnaの送達

Country Status (6)

Country Link
US (1) US20150216814A1 (https=)
EP (1) EP2906242A1 (https=)
JP (1) JP2016500681A (https=)
CA (1) CA2888135A1 (https=)
IL (1) IL238245A0 (https=)
WO (1) WO2014059430A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016073706A1 (en) * 2014-11-06 2016-05-12 Board Of Regents, The University Of Texas System Delivery of small interfering rna and micro rna through nanogels containing hydrophobic pseudo-peptides
MX2018005146A (es) * 2015-10-30 2018-08-23 Bonac Corp Composicion que contiene de manera estable molecula de acido nucleico de un solo filamento que suprime la expresion de gen tgf-b1.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4060678A (en) * 1975-02-11 1977-11-29 Plastomedical Sciences, Inc. Cationic hydrogels based on hydroxyalkyl acrylates and methacrylates
JP3713841B2 (ja) * 1996-10-08 2005-11-09 荒川化学工業株式会社 カチオン性微粒子ゲルおよびその製造方法
US7378479B2 (en) * 2002-09-13 2008-05-27 Lubrizol Advanced Materials, Inc. Multi-purpose polymers, methods and compositions
AU2009256423A1 (en) * 2008-06-03 2009-12-10 Novartis Ag Pulsatile release of valsartan
GB201010831D0 (en) * 2010-06-28 2010-08-11 Ct Angewandte Nanotech Can A micellular combination comprising a nanoparticle and a plurality of surfmer ligands

Similar Documents

Publication Publication Date Title
Ghaffari et al. Surface functionalized dendrimers as controlled-release delivery nanosystems for tumor targeting
Pandey et al. Polyethylenimine: A versatile, multifunctional non-viral vector for nucleic acid delivery
Li et al. New route to amphiphilic core− shell polymer nanospheres: graft copolymerization of methyl methacrylate from water-soluble polymer chains containing amino groups
Cao et al. Recent advances of zwitterionic carboxybetaine materials and their derivatives
Ulbrich et al. Structural and chemical aspects of HPMA copolymers as drug carriers
Wong et al. Modulating antimicrobial activity and mammalian cell biocompatibility with glucosamine-functionalized star polymers
Zurick et al. Recent biomedical advances with polyampholyte polymers
CN105250214B (zh) 一种氨基酸修饰的聚合物纳米水凝胶药物载体的制备方法
US20150283254A1 (en) Polymeric nanoparticles
RU2017129933A (ru) Доставка частиц гидрофобного активного средства
Varkouhi et al. Polyplexes based on cationic polymers with strong nucleic acid binding properties
JP2017513596A5 (https=)
RU2013135454A (ru) Системы доставки лекарств
KR20050025164A (ko) pH-민감성 중합체
Ahmed et al. Cell line dependent uptake and transfection efficiencies of PEI–anionic glycopolymer systems
Forbes et al. Polycationic nanoparticles synthesized using ARGET ATRP for drug delivery
JP2017535581A5 (https=)
MX341715B (es) Polímeros anfifílicos de autoensamblaje como agentes anticáncer.
JP2015120756A5 (https=)
Plamper et al. Star-shaped poly [2-(dimethylamino) ethyl methacrylate] and its derivatives: toward new properties and applications
JP2017514005A5 (https=)
CN102973488A (zh) 具有氧化还原/pH双重刺激响应性的纳米水凝胶及其制备方法和应用
Tripathi et al. Polyethylenimine-polyacrylic acid nanocomposites: type of bonding does influence the gene transfer efficacy and cytotoxicity
JP2016500681A5 (https=)
Malcolm et al. Diblock copolymer hydrophobicity facilitates efficient gene silencing and cytocompatible nanoparticle-mediated siRNA delivery to musculoskeletal cell types